Drug Eluting Balloons will Drug-Eluting Balloons ... - summitMD.com

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(4) Particulate Coating Formation Local Tissue Effects Transit Drug Loss Acute Drug Transfer Micro-Particles DCB Acute Drug Transfer Macro-Particles • Vascular occlusions. • Tissue drug effect. • End-organ effects.
Conclusions: PCB Technologies • PCB technologies continue to show efficacy in reducing restenosis in specific clinical scenarios (i.e., ISR). • However, the synergistic use of stents must be carefully studied in a prospective manner in a larger population. • Newer generations of PCB appear to offer improved coating platforms providing more precise drug transfer to the tissue. • Preliminary data suggests that specific features of the coating regulates the long-term transfer and retention ti of the drug. • The real clinical effect of micro-particle drug release into distal tissues needs to be carefully evaluated against the potential therapeutic benefit of this technology. • If proper technical balance is achieved (acute transfer-tissue ti levels-particulate formation), PCB have the potential to become a strong competitor in the PCI arena.
Page 1 and 2: Drug-Eluting Balloons will Have an
Page 3 and 4: Drug Coated Balloon Technologies A
Page 5 and 6: PCB for the Treatment of ISR Angiog
Page 7 and 8: Clinical Outcomes Among 250 Patient
Page 9 and 10: PCB for the Treatment of De Novo SF
Page 11 and 12: Vascular Healing Following PCB Use
Page 13 and 14: Synergistic Use of PCB and BMS Less
Page 15 and 16: (1) Systemic Release of Paclitaxel
Page 17 and 18: Deposition of a Drug Delivery Biofi
Page 19: (3) Local Tissue Effects (Safety) V

Drug Eluting Balloons will Drug-Eluting Balloons ... - summitMD.com

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