utilizing proteomics to characterize hair and hair damage
utilizing proteomics to characterize hair and hair damage
utilizing proteomics to characterize hair and hair damage
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INTRODUCTION<br />
• Proteins are the major<br />
structural component<br />
of <strong>hair</strong> (~80-90%)<br />
Component<br />
Protein<br />
Lipid<br />
Protein bound sulfur<br />
Sugars<br />
Ash<br />
Zinc<br />
Melanin (black <strong>hair</strong>)<br />
Approximate content<br />
by dry weight of <strong>hair</strong><br />
91%<br />
4%<br />
4.7%<br />
1.0%<br />
0.5%<br />
200 ppm<br />
4%<br />
Feughelman et al. J. Appl. Polm. Sci., 2002, 83,489.<br />
• Hair is not regenerative after it exits the scalp; therefore, maintaining<br />
proper <strong>hair</strong> architecture at the molecular level is an important hallmark for<br />
a healthy <strong>hair</strong> structure<br />
• Ultimately, proper <strong>hair</strong> protein structure has an important impact on the<br />
cosmetic value of the <strong>hair</strong> shaft
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