12.3 MELISSA OFFICINALIS and relaxation Authoritative bodies ...

12.3 MELISSA OFFICINALIS and relaxation
Authoritative bodies
- European Agency for the Evaluation of Medicinal Products, Working Party on Herbal Medicinal
Products. Draft proposal for a core data for Melissa leaf. 31/03/2000. EMEA/HMPWP/19/00.
Monographs
- The Complete German Commission E Monographs. Therapeutic guide to herbal medicines.
Ed. By M. Blumenthal, W. Busse, A. Goldberg, J. Gruenwald, T. Hall, C. Riggins & R. Rister.
American Botanical Council, USA, 1998
- Herbal Medicine, Expanded Commission E monographs. Ed. By M. Blumenthal, A. Goldberg &
J. Brinckmann. American Botanical Council, USA, 2000
- ESCOP monographs. The scientific foundation for herbal medicinal products. 2nd ed. The
European Scientific Cooperative on Phytotherapy, Georg Thieme Verlag, Germany, 2003
- British Herbal Pharmacopoeia, British Herbal Medicine Asociation, 1983
- Blumenthal M, Goldberg A, Brinckmann J. Herbal Medicine, Expanded Commission E
Monographs. 2000, American Botanical Council, Austin TX, pages 230-2.
- Swedish Medical Center. Herbs&Supplements: Lemon Balm, Melissa officinalis
http://www.swedish.org/body_frameset.cfm?id=1009 (03-10-2006)
- University of Maryland Medical centre. Lemon Balm
http://www.umm.edu/altmed/ConsHerbs/print/lemonbalmch.html (20-07-2006).
- WHO Monographs on selected medicinal plants, vol. 2, 2002, page 180-7, Folium Melissae
Textbooks
- European Pharmacopoeia 5.0, vol. 2, 2005, monograph Melissa leaf (01/2005:1447).
- Gruenwald J, Brendler T, Jaenicke C. PDR for herbal medicines, first edition. 1998, Medical
Economics Company, Montvale NJ, pages 967-9.
Critical review
- CKF. Master file Melissae Folium, October 2006
140
- Wheatley D. Medicinal plants for insomnia: a review of their pharmacology, efficacy and
tolerability. J Pschychopharmacol. 2005;19(4):414-21.
Individual studies
- Akhondzadeh S, Noroozian M, Mohammadi M, Ohadinia S, Jamshidi AH, Khani M. Melissa
officinalis extract in the treatment of patients with mild to moderate Alzheimer’s disease: a
double blind, randomized, placebo controlled trial. J Neurol Neurosurg Psychiatry.
2003;74(7):863-6.
- Allahverdiyev A, Duran N, Ozguven M, Koltas S. Antiviral activity of the volatile oils of Melissa
officinalis L. against Herpes Simplex virus type-2, Phytomedicine. 2004;11(7-8):657-61.
- Ballard CG, O’Brien JT, Reichelt K, Perry EK. Aromatherapy as a save and effective treatment
for the management of agitation in severe dementia: the results of a double-blind, placebocontrolled
trial with Melissa. J Clin Psychiatry. 2002;63(7):553-8.
- Bolkent S, Yanardag R, Karabulut-Bulan O, Yesilyaprak B. Protective role of Melissa officinalis
L. extract on liver of hyperlipidemic rats: A morphological and biochemical study. J
Ethnoparmacol. 2005;99:391-8.
- Cerny A, Schmid K. Tolerability and efficacy of valerian/lemon balm in healthy volunteers (a
double-blind, placebo controlled, multicentre study). Fitoterapia. 1999;70:221-8.
- Ferreira A, Proenca C, Serralheiro MLM, Araujo MEM. The in vitro screening for
acetylcholinesterase inhibition and antioxidant activity of medicinal plants from Portugal. J
Ethnopharm. 2006;[Epub Ahead of print].
- Kennedy DO, Little W, Haskell CF, Scholey AB. Anxiolytic effects of a combination of Melissa
officinalis and valeriana officinalis during laboratory induced stress. Phytother Res. 2006;20:96-
102.
- Kennedy DO, Scholey AB, Tildesley NTJ, Perry EK, Wesnes KA. Modulation of mood and
cognitive performance following acute administration of Melissa officinalis (lemon balm).
Pharmacol Biochem Behav. 2002;72(4):953-64.
- Kennedy DO, Wake G, Savelev S, Tildesley NTJ, Perry EK, Wesnes KA, Scholey AB.
Modulation of mood and cognitive performance following acute administration of single doses
of Melissa officinalis (Lemon Balm) with human CNS nicotinic and muscarinic receptor-binding
properties. Neuropsychopharmacology. 2003;28(10):1871-81.
- Kennedy DO, Little W, Scholey AB. Attenuation of laboratory-induced stress in humans after
acute administration of Melissa officinalis (Lemon Balm). Psychosom Med. 2004;66(4):607-13.
- Madisch A, Holtmann G, Mayr G, Vinson B, Hotz J. Treatment of functional dyspepsia with a
herbal preparation. A double-blind, randomized, placebo-controlled multicenter trial. Digestion.
2004;69(1):45-52.
- Müller SF, Klement S. A combination of valerian and lemon balm is effective in the treatment of
restlessness and dyssomnia in children. Phytomedicine. 2006;13:383-7.
- Sadraei H, Ghannadi A, Malekshahi K. Relaxant effect of essential oil of Melissa officinalis and
citral on rat ileum contractions. Fitotherapia. 2003;74:445-52.
- Savino F, Cresi F, Castagno E, Silvestro L, Oggero R. A randomized double-blind placebocontrolled

trial of a standardized extract of Matricariae recutita, Foeniculum vulgare and
Melissa officinalis (ColiMil) in the treatment of breastfed colicky infants. Phytother Res.
2005;19(4):335-40.
- Schemann M, Michel K, Zeller F, Hohenester B, Rühl A. Region-specific effects of STW-5
(Iberogast) and its components in gastric fundus, corpus and antrum. Phytomedicine.
2006;[Epub Ahead of print].
141
- Sibaev A, Yuece B, Kelber O, Weiser D, Schirra J, Göke B, Allescher HD, Storr M. STW-5
(Iberogast) and its individual herbal components modulate intestinal electrophysiology of mice.
Phytomedicine. 2006;[Epub Ahead of print].