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Exhibitors at UBIFRANCE French Pavilion

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SYNTHELIS<br />

B<strong>at</strong>iment Biopolis<br />

5 avenue du Grand Sablon<br />

38700 LA TRONCHE - FRANCE<br />

Phone: +33 4 76 54 95 37<br />

Fax: +33 4 76 54 95 36<br />

Email: bruno.tillier@synthelis.fr<br />

Web site: www.synthelis.fr<br />

Contact: Bruno TILLIER<br />

Synthelis SAS is a start-up company providing a solution to a well known challenge<br />

in terms of biotechnological production, namely the development, characteriz<strong>at</strong>ion<br />

and production of customized membrane proteins and associ<strong>at</strong>ed service offerings.<br />

The company is also working on its own R&D programs with a view to developing<br />

innov<strong>at</strong>ive therapeutic and vaccine approaches based on membrane protein carried<br />

into liposomes<br />

TB DRUG BOOST<br />

3 rue du Professeur Laguesse<br />

59000 LILLE - FRANCE<br />

Phone: +33 3 20 96 40 24<br />

Fax: +33 3 20 96 49 07<br />

Web site: www.deprezlab.fr<br />

Anti-infective drug discovery. We have developed a pl<strong>at</strong>form specialized in screening<br />

for bacterial repressor inhibitiors. Our first program has produced several series<br />

specific nanomolar, bioavailable inhibitors of EthR, a myco-bacterial repressor. In vivo,<br />

these compounds boost the activity of ethionamide, a key antibiotic used in TB. Our<br />

series has reached the level of regul<strong>at</strong>ory development. We are seeking a partnership<br />

for the development of these compounds th<strong>at</strong> have a clinical utility in the tre<strong>at</strong>ment of<br />

MDR strains of tuberculosis.<br />

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