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Quality Control in Clinical Trials

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2. Outlier test (Tukey)<br />

a. Rank data, divide <strong>in</strong>to percentiles<br />

(quartiles)<br />

b. Identify 25th, 75th percentiles,<br />

difference between them<br />

(<strong>in</strong>terquartile range)<br />

c. Def<strong>in</strong>e upper limit as 75th<br />

percentile plus <strong>in</strong>terquartile range<br />

d. Def<strong>in</strong>e lower limit as 25th percentile<br />

m<strong>in</strong>us <strong>in</strong>terquartile til range<br />

e. Reanalyze without outliers, report<br />

both

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