Discovery of Potent HIV-1 Capsid Assembly Inhibitors
Discovery of Potent HIV-1 Capsid Assembly Inhibitors
Discovery of Potent HIV-1 Capsid Assembly Inhibitors
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<strong>Capsid</strong> <strong>Assembly</strong> Assay (CAA)<br />
In the context <strong>of</strong> CA-NC, nucleic acid enhances<br />
the formation <strong>of</strong> capsid-like complexes in vitro<br />
CA-NC<br />
+<br />
probe<br />
B<br />
B<br />
B<br />
Streptavidin<br />
<strong>Assembly</strong> phase wash detect<br />
Boehringer Ingelheim - CROI 2010 3