CV - Department of Molecular and Cellular Biology - Harvard ...

Rachelle Gaudet, PhD
Curriculum Vitae
RESEARCH PUBLICATIONS (CONTINUED)
K. Artavanis-Tsakonas, W. A. Weihofen, J. M. Antos, B. I. Coleman, C. A. Comeaux, M. T.
Duraisingh, R. Gaudet, H. L. Ploegh (2010) Characterization and structural studies of the
Plasmodium falciparum ubiquitin and Nedd8 hydrolase UCHL3. Journal of Biological
Chemistry 285, 6857-66. PMCID: PMC2825479
C. B. Phelps, R. R. Wang, S. S. Choo and R. Gaudet (2010) Differential Regulation of TRPV1,
TRPV3 and TRPV4 Sensitivity through a Conserved Binding Site on the Ankyrin Repeat
Domain. Journal of Biological Chemistry, 285, 731-40. PMCID: PMC2804222
E. Procko and R. Gaudet (2008) Functionally Important Interactions between the Nucleotide-
Binding Domains of an Antigenic Peptide Transporter. Biochemistry 47, 5699-708.
C. B. Phelps, R. J. Huang, P. V. Lishko, R. R. Wang and R. Gaudet (2008) Structural analyses of
the ankyrin repeat domain of TRPV6 and related TRPV ion channels. Biochemistry 47, 2476-
2484. PMCID: PMC3006163
C. B. Phelps and R. Gaudet (2007) The Role of the N-Terminus and Transmembrane Domain of
TRPM8 in Channel Localization and Tetramerization. Journal of Biological Chemistry 282,
36474-80.
P. C. Sabeti, P. Varilly, B. Fry, J. Lohmueller, E. Hostetter, C. Cotsapas, X. Xie, E. H. Byrne, S.
A. McCarroll, R. Gaudet, S. F. Schaffner, E. S. Lander & The International HapMap Consortium
(2007) Genome-wide detection and characterization of positive selection in human populations.
Nature 449, 913-918. PMCID: PMC2687721
C. B. Phelps, E. Procko, P. V. Lishko, R. R. Wang, and R. Gaudet (2007) Insights into the Roles
of Conserved and Divergent Residues in the Ankyrin Repeats of TRPV Ion Channels. Channels
1, 148-151.
P. V. Lishko, E. Procko, X. Jin, C. B. Phelps and R. Gaudet (2007) The Ankyrin Repeats of
TRPV1 Bind Multiple Ligands and Modulate Channel Sensitivity. Neuron 54, 905-918.
C. Schlieker, W. A. Weihofen, E. Frijns, L. M. Kattenhorn, R. Gaudet and H. L. Ploegh (2007)
Structure of a Herpesvirus-Encoded Cysteine Protease Reveals a Unique Class of
Deubiquitinating Enzymes. Mol. Cell 25, 677-687.
E. Procko, I. Ferrin-O’Connell, S.-L. Ng, and R. Gaudet (2006) Distinct structural and functional
properties of the ATPase sites in an asymmetric ABC transporter. Mol. Cell 24, 51-62.
X. Jin, J. Touhey, and R. Gaudet (2006). Structure of the N-terminal ankyrin repeat domain of
the TRPV2 ion channel. J. Biol. Chem. 281, 25006-25010.
E. Procko, G. Raghuraman, D. C. Wiley, M. Raghavan, and R. Gaudet (2005) Domain
boundaries are identified within the N-termini of TAP1 and TAP2 important for tapasin binding
and tapasin-mediated increase in peptide loading of MHC class I. Immunol. Cell Biol. 83, 475-
82.
S. Misaghi, P. J. Galardy, W. J. N. Meester, H. Ovaa, H. L. Ploegh, and R. Gaudet (2005)
Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate. J. Biol. Chem.
280, 1512-1520.
S. Misaghi, Z.-Y. J. Sun, P. Stern, R. Gaudet, G. Wagner and H. L. Ploegh (2004) A structural
and functional analysis of the human cytomegalovirus US3 protein. J. Virol. 78, 413-423.
PMCID: PMC303419
Page 4 of 13