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Antiphospholipid Syndrome.

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Thrombosis and aPL Antibodies<br />

• SLE:<br />

aCL in 12-30% of patients<br />

LA in 15-34% of patients<br />

aCl and LA in 38% of pts with aPL<br />

• Prevalence of thrombosis in SLE patient with aPL:<br />

50% (venous, arterial, small vessel)<br />

• Incidence of thrombosis in SLE patient with aPL:<br />

Two per 100 person years of followup<br />

(Petri M: Scand J Rheumatol 1996;25:191)<br />

New event in 7% of pts over 5 years<br />

(Cervera R et al: Medicine (Baltimore) 1999;78:167)

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