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Antiphospholipid Syndrome.

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<strong>Antiphospholipid</strong> <strong>Syndrome</strong><br />

Thrombotic Manifestations<br />

• Venous thrombosis<br />

55% of cases, half of whom have PE<br />

- Predominantly lower limb<br />

• Arterial thrombosis<br />

45% of cases<br />

- 50% CNS (TIA, stroke)<br />

- 25% coronary arteries<br />

- 25% eye, kidney, limb vessels<br />

(Asherson RA et al: Medicine (Baltimore) 1989;68:366. Alarcon-Segovia D et al: Semin<br />

Arthritis Rheum 1992;21:275. Vianna JL et al: Am J Med 1994;96:3)

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