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Is treating Blood pressure alone enough to protect your

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Treating a Single Risk Fac<strong>to</strong>r is Not Enough:<br />

Event (%)<br />

f Primary E<br />

Risk of<br />

100<br />

90<br />

80<br />

70<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

Risk reduction (%) Events not avoided (%)<br />

CV Risk 64<br />

Remains Even After<br />

75<br />

72<br />

86<br />

Antihypertensive Therapy in<br />

Placebo-Controlled 36<br />

Studies<br />

SHEP (chlorthalidone<br />

+/- atenolol)<br />

25<br />

MRC-O (HCTZ +<br />

atenolol)<br />

14<br />

Syst-Eur (nitrendipine,<br />

enalapril, HCTZ)<br />

28<br />

PROGRESS<br />

(perindopril +/-<br />

diuretic)<br />

SHEP Cooperative Research Group. JAMA. 1991;265:3255-3264. MRC Working Party. BMJ. 1992;304:405-412.<br />

Staessen JA et al, for the Syst-Eur Trial Investiga<strong>to</strong>rs. Lancet. 1997;350<br />

350:757-764. PROGRESS Collaborative Group.<br />

Lancet. 2001;358:1033-1041.

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