Parkinson's disease - University of Minnesota Continuing Medical ...
Parkinson's disease - University of Minnesota Continuing Medical ...
Parkinson's disease - University of Minnesota Continuing Medical ...
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Glutamate Modulating Medications<br />
Symmetrel® (amantadine)<br />
<br />
Natural History <strong>of</strong> Parkinson’s <strong>disease</strong><br />
Neuroprotective Rx Research Symptomatic Medication Rx<br />
DBS surgery<br />
-5 0 .5 - 1 1-1.51.5 4-10<br />
8-15<br />
12-20<br />
20<br />
rimantadine<br />
Flumadine®<br />
(rimantadine)<br />
Leg swelling,<br />
livedo reticularis,<br />
confusion, etc.<br />
Livedo reticularis<br />
Skin changes<br />
Symptoms<br />
Treatment<br />
Falls, swallowing,<br />
first<br />
begins<br />
bladder, cognitive<br />
appear<br />
problems, etc.<br />
Onset <strong>of</strong><br />
Diagnosis is<br />
<strong>disease</strong><br />
made<br />
Motor Complications<br />
(dyskinesias/fluctuations) begin<br />
Walker,<br />
cane,<br />
wheelchair<br />
for balance<br />
Motor Features As PD<br />
Advances<br />
Motor fluctuations: varying states <strong>of</strong><br />
mobility, which may or may not occur at<br />
a specific time in relation to their<br />
medication<br />
Dyskinesias: involuntary movements (not<br />
tremor), record when they occur -<br />
specifically in relation to their medication<br />
& time <strong>of</strong> day<br />
Often after 5-10 years<br />
motor fluctuations and dyskinesias occur
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