Acute Coronary Syndrome
Acute Coronary Syndrome
Acute Coronary Syndrome
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Pravastatin Or atorVastatin Evaluation and<br />
Infection Therapy–Thrombolysis Thrombolysis In Myocardial<br />
Infarction 22 (PROVE-IT TIMI 22)<br />
• 4,162 patients within 10 d of ACS<br />
•40 mg pravastatin vs 80 mg atorvastatin daily<br />
•↓ All-cause death, MI, UA requiring hosp, revasc & stroke @ 2 y by<br />
atorvastatin<br />
― Median LDL-C ↓ (62 vs 95 mg/dL)<br />
Cannon CP, et al. N Engl J Med 2004;350:1495–504.