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Acute Coronary Syndrome

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Antiplatelet Therapy<br />

I<br />

IIa IIb III<br />

See recommendation for LOE<br />

Major<br />

Change<br />

For UA/NSTEMI patients treated medically<br />

without stenting, aspirin* (75 to 162 mg per day)<br />

should be prescribed indefinitely (Level of<br />

Evidence: A)<br />

clopidogrel† †( (75 mg gp per day) should be<br />

prescribed for at least 1 month (Level of<br />

Evidence: A) and ideally for up to 1 year. (Level of<br />

Evidence: B)<br />

*For ASA-allergic patients, use clopidogrel alone (indefinitely), or try aspirin desensitization.<br />

†For clopidogrel-allergic patients, use ticlopidine 250 mg by mouth twice daily.<br />

46

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