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L A M B I O T T E & C I E S. A. 1 , 3 - D I O X O L A N E Description Molecular formula C 3 H 6 O 2 Chemical structure Synonym 1,3-dioxacyclopentane CAS N° 646-06-0 EINECS N° 211-463-5 INCI name Elcotal DX Physical Properties Molecular weight 74.08 Density (g/cm 3 ) 20°C 1.06 Vapour density 2.6 Boiling point (°C) 101 325 Pa 74-75 Freezing point (°C) -95 Flash point (°C) Closed cup (Pensky-Martens) -6 Open cup (Cleveland) 2 Vapour pressure (bar) 20°C (ASTM D 323 modified) 0.09 Kinematic viscosity (10 -7 m 2 /s) 25°C 5.53 Refractory index η 20 D 1.4005 Explosion limits (Vol%) LEL 45 : 2.1 UEL 65 : 20.5 Autoignition temperature (°C) (ASTM E 659) 274 Surface tension (mN/m) 25°C 34.3 Evaporation rate compared to Diethyl ether (= 1) 3.60 (Following DIN 53170) Butyl acetate (= 1) 0.29 Solubility of the acetal in water (%) Fully miscible Solubility of water in the acetal (%) Fully miscible Solvent power Kauri-butanol index (ASTM D 1133-90) measured with gum 4938 >218 gum 4939 >207 Solubility parameters (MPa 1/2 ) Hildebrand: Total δ 22.07 Hansen: Dispersion δ d 16.95 Polarity δ p 7.85 Hydrogen bond δ h 11.76 Azeotrope Binary (homogeneous) % Weight 1,3-dioxolane % Weight water B.P. temperature (°C) Pressure (Pa) 91.30 8.70 71.7 102 390 10
Toxicological Information Inhalation, rabbit: Inhalation, male rat: Inhalation, Sprague-Dawley rat: Inhalation, guinea pig: Oral, mouse: Oral, rat: Dermal, albino rabbit: Subchronic inhalation, rat (13 weeks): LC 50 = 118 mg / l LC 50 = 87mg / l / 4 hours LC 50 = 68.4 mg / l LC 50 = 166 mg / l / 4 hours LD 50 = 7460 mg / kg LD 50 = 5800 mg / kg LD 50 = 15 000 mg / kg NOEL = 300 ppm Teratogenicity, oral, 10 or 20% of the LD 50 one each day 5 days/week (8 weeks): Teratogenicity, inhalation, rat, no loss of foetuses occurred 10 and 20% of the LC 50 : no increases in pre- or post-implantation foetal losses Teratogenicity, intragastric, rat, 10 and 20% of the LD 50 : no increases in pre- or post-implantation foetal losses Ames test up to 10 μl: Ames test at the equivalent of 50 μl / plate: no mutagenic activity both in presence or in absence of microsomal enzyme preparation no mutagenic activity both in presence or in absence of metabolic activation Carcinogenicity: not listed by ACGIH, IARC, NTP or CA Prop 65 Ecological Information Terrestrial: Aquatic: Atmospheric: High mobility in soil and leaching may occur. 1,3-dioxolane may volatilize from moist soil. Volatilization half-lives of 34 hr and 15 days have been estimated for a model river and a model environmental pond, respectively. Adsorption to sediment and bioconcentration in aquatic organisms may not be important. Expected to exist almost entirely in the vapour phase in the ambient atmosphere. Will not bioconcentrate but may slightly biodegrade. Regulatory Information Europe EINECS (European Inventory of Existing Commercial chemical Substances) 211-463-5 Germany WGK (Wassergefährdungsklasse) 1 USA TSCA (Toxic Substances Control Act) Listed on the TSCA inventory California Prop 65 Not listed California No Significant Risk Level Canada DSL/NDSL (Domestic Substances List) (Non-Domestic Substances List) Listed on DSL List WHMIS (Workplace Hazardous Materials Information System) This product has a WHMIS classification of B2 Japan ENCS Japanese Gazette 5-500 Korea ECL (Korean Existing Chemicals List) KE-12027 Philippines PICCS (Philippines Inventory of Chemicals and Chemical Substances) Listed on the PICCS inventory 11
Page 1 and 2: L A M B I O T T E & C I E S . A . A
Page 3 and 4: A C E T A L S P R O D U C T R A N G
Page 5 and 6: Toxicological Information Inhalatio
Page 7 and 8: Azeotropes Binary (non homogeneous)
Page 9: Toxicological Information Oral, rat
Page 13 and 14: Toxicological Information Oral, mou
Page 15 and 16: S O L V E N T P R O P E R T Y T A B

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