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Ethnic differences - intrinsic and extrinsic factors

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Exon 7 NOS3 in afro-american (AA) pts<br />

A-HeFT <strong>and</strong> GRACE registry<br />

NOS3<br />

exon 7<br />

GRACE<br />

Non-AA<br />

GRACE<br />

A-A<br />

A-<br />

HeFT<br />

Asp-Asp<br />

(%)<br />

Asp-Glu<br />

(%)<br />

Glu-Glu<br />

(%)<br />

14 2 1<br />

45 31 20<br />

41 67 79<br />

Taylor A et al , Circulation 2007<br />

McNamara DM et al. Journal of<br />

Cardiac Failure Vol. 15 No. 3 2009

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