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Ethnic differences - intrinsic and extrinsic factors

Ethnic differences - intrinsic and extrinsic factors

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Conclusions<br />

• Globalization of trials is a necessity<br />

• Regional <strong>differences</strong> should not play against<br />

globalization of clinical trials<br />

• Subgroup analyses based on regions have<br />

rarely changed the main results of HF trials (No<br />

interaction found)<br />

• Balance among regions represented in a trial is<br />

important in order to avoid over-representation<br />

of a region <strong>and</strong> interpretation bias.

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