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Read it in pdf format - Baystate Health

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a transseptal catheterization. Dur<strong>in</strong>g this procedure,<br />

a needle is used to make small hole <strong>in</strong> the septum<br />

divid<strong>in</strong>g the two atria. The catheter is then threaded<br />

from one atrium to the other. After the procedure,<br />

the hole closes on <strong>it</strong>s own.<br />

“Access from the right atrium to the left is more<br />

difficult and takes longer,” says Dr. Stoenescu. “Also,<br />

try<strong>in</strong>g to isolate the pulmonary ve<strong>in</strong>s by go<strong>in</strong>g <strong>in</strong> a<br />

po<strong>in</strong>t-to-po<strong>in</strong>t fashion so the electrical current can’t<br />

slip through is tedious work.”<br />

The average PVI procedure takes four to five hours<br />

to complete compared to other ablation procedures,<br />

which typically take less than two hours.<br />

Outcomes and Risks<br />

PVI is most effective <strong>in</strong> the <strong>in</strong><strong>it</strong>ial stages of atrial<br />

fibrillation — paroxysmal AF — dur<strong>in</strong>g which the<br />

heart beats <strong>in</strong> a normal rhythm w<strong>it</strong>h occasional<br />

episodes of arrhythmia. Dr. Fox says patients w<strong>it</strong>h<br />

paroxysmal AF respond well to the procedure, w<strong>it</strong>h<br />

a 70 to 80 percent success rate.<br />

The procedure’s effectiveness goes down <strong>in</strong> cases of<br />

persistent AF, when the arrhythmia is usually present<br />

w<strong>it</strong>h <strong>in</strong>frequent, short-lived episodes of normal s<strong>in</strong>us<br />

rhythm, and <strong>in</strong> permanent AF, <strong>in</strong> which patients are<br />

almost always <strong>in</strong> atrial fibrillation. “In the latter two<br />

stages of AF,” says Dr. Stoenescu, “the success rate<br />

drops to around 60 percent.”<br />

While PVI is effective at stopp<strong>in</strong>g atrial fibrillation,<br />

<strong>it</strong> is not w<strong>it</strong>hout risk. As w<strong>it</strong>h any catheterization,<br />

there is a slight risk of damag<strong>in</strong>g blood vessels when<br />

the catheter is <strong>in</strong>serted and directed toward the heart.<br />

Ablat<strong>in</strong>g <strong>in</strong> or near the pulmonary ve<strong>in</strong>s can, <strong>in</strong> some<br />

cases, lead to stenosis and reduced blood flow to the<br />

heart. In add<strong>it</strong>ion, cauteriz<strong>in</strong>g the tissue can <strong>in</strong>crease<br />

the risk of blood clots, which if dislodged, can lead<br />

to stroke.<br />

Pulmonary ve<strong>in</strong> isolation is<br />

<strong>in</strong>creas<strong>in</strong>gly be<strong>in</strong>g used to treat<br />

AF, w<strong>it</strong>h excellent results.<br />

Perhaps the most serious complication of PVI is<br />

atrial-esophageal fistula between the left atrium and<br />

the adjacent esophagus caused by the RF energy used<br />

to ablate abnormal tissue. Dr. Fox says that while<br />

atrial-esophageal fistula is a “dangerous” complication,<br />

<strong>it</strong> is rare, occurr<strong>in</strong>g <strong>in</strong> less than one percent of patients.<br />

The biggest challenge doctors face <strong>in</strong> controll<strong>in</strong>g<br />

atrial fibrillation is learn<strong>in</strong>g more about the cond<strong>it</strong>ion.<br />

“Ablation for other forms of arrhythmia has a 90 to<br />

100 percent success rate,” says Dr. Fox, “because we<br />

know more about and understand these types of<br />

arrhythmias and how to get rid of them. We’re still<br />

learn<strong>in</strong>g about AF and how <strong>it</strong> responds to ablation.”<br />

For more <strong>in</strong><strong>format</strong>ion<br />

or to refer a patient, call 413-794-7246.<br />

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