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<strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

Annual Report 2010<br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

NewYork-Presbyterian Hospital<br />

Annual Report 2011 103


Dear Colleagues and Friends:<br />

I am pleased to present the 3rd Annual Report <strong>of</strong> the <strong>Department</strong> <strong>of</strong><br />

<strong>Medicine</strong> <strong>of</strong> <strong>Weill</strong> <strong>Cornell</strong> Medical College and the NewYork-Presbyterian<br />

Hospital/<strong>Weill</strong> <strong>Cornell</strong> Medical Center. The past calendar year (2010)<br />

was one <strong>of</strong> remarkable progress. Many <strong>of</strong> our 2010 groundbreaking<br />

initiatives are highlighted in this report.<br />

Table <strong>of</strong> Contents<br />

Welcome from the Chairman 1<br />

Creating New Beginnings Out <strong>of</strong> Chaos: 2<br />

Dr. Jean W. Pape, A Distinguished Career<br />

Building a Defense Against Resistance: 6<br />

Hospital-acquired Infections<br />

Promoting Better Sleep for Better Overall Health: 8<br />

<strong>Weill</strong> <strong>Cornell</strong> Center for Sleep <strong>Medicine</strong> Opens<br />

Establishing Hospital <strong>Medicine</strong>: 10<br />

A New System Within the System<br />

ADVANCE Trial Advances: 12<br />

Superior Viral Response Rates Using Telaprevir<br />

A Front-runner <strong>of</strong> Personalized <strong>Medicine</strong>: 15<br />

Dr. Marcus Reidenberg Receives ASPET Award<br />

GHESKIO Research Leads to Change in WHO Guidelines: 16<br />

Earlier Treatment is Better for HIV/AIDS<br />

Where do Medical Research and Social Media Meet? 16<br />

The Physician-Scientist? 18<br />

Endangered but not Vanishing<br />

New Leadership Appointments 20<br />

Honors and Awards 23<br />

Division Pr<strong>of</strong>iles 35<br />

Faculty Members 69<br />

Research Highlights 77<br />

Medical Education 95<br />

Residents and Fellows on the Move 96<br />

Educational Opportunities in Global Health 114<br />

Alumni: Then and Now 119<br />

Financial Report 121<br />

Donors 124<br />

Contacts 136<br />

In the latter half <strong>of</strong> 2010, within a compressed period <strong>of</strong> six months, the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> crafted<br />

a comprehensive Strategic Plan, entitled Building Cohesion and Driving Value in the 21st Century. Our Strategic<br />

Plan was the product <strong>of</strong> an intensive, faculty-driven analysis <strong>of</strong> the department’s current position, coupled with<br />

prioritized recommendations and timelines for implementing strategic directions moving forward. The process<br />

culminated in a series <strong>of</strong> four <strong>of</strong>f-campus retreats encompassing all <strong>of</strong> our missions and involving over 140 faculty<br />

and staff participants. In response to powerful economic, political and scientific forces driving reform <strong>of</strong> the<br />

U.S. health care system, the Strategic Plan embraced two essential ideas, as its title suggests: (1) achieving high<br />

value for patients as the overarching goal, and (2) promoting cohesion and real teamwork in achieving this goal.<br />

These principles were applied, not only to our clinical mission, but also to our educational and research missions,<br />

all <strong>of</strong> which must exist interdependently.<br />

Among the year’s highlights: initiated an innovative Faculty Development Program, under the leadership<br />

<strong>of</strong> Dr. Art Evans; launched a clinical research infrastructure to catalyze and facilitate high-impact clinical and<br />

patient-oriented research in the department, under the leadership <strong>of</strong> Dr. John Leonard; expanded our vibrant<br />

new educational and clinical partnership with the Cayuga Medical Center in Ithaca; opened a beautiful, 12-bed,<br />

state-<strong>of</strong>-the-art interdisciplinary Sleep Center, under the direction <strong>of</strong> Dr. Ana Krieger and in partnership with the<br />

<strong>Department</strong> <strong>of</strong> Neurology; and completed the build-out <strong>of</strong> new Hematology-Oncology suites on two floors<br />

<strong>of</strong> the <strong>Weill</strong> Greenberg Building.<br />

Among new major leadership positions: we welcomed Dr. Lia Logio, recruited from Indiana University to be<br />

Vice Chair for Education and Director <strong>of</strong> the Internal <strong>Medicine</strong> Residency Program; Tipton (“Tip”) Ford, recruited<br />

from the University <strong>of</strong> Cincinnati to be Chief Administrative Officer and Vice Chair for Business Affairs; and<br />

Dr. Mary Crow as Chief <strong>of</strong> the Rheumatology Division and Physician-in-Chief <strong>of</strong> the Hospital for Special Surgery.<br />

The <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> also created 7 new endowed chairs (bringing the total to 43) and 5 new Clinical<br />

Scholar Awards (bringing the total to 18).<br />

So, it is with great pride that I share with you the accomplishments <strong>of</strong> the past year by an extraordinarily dedicated<br />

and gifted group <strong>of</strong> faculty, staff and trainees. I welcome your comments and thank you for your support.<br />

Andrew I. Schafer, M.D.<br />

The E. Hugh Luckey Distinguished Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Chair, <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Physician-in-Chief<br />

NewYork-Presbyterian Hospital/<strong>Weill</strong> <strong>Cornell</strong> Medical Center<br />

Cover Photo: Dr. Barbara L. Hempstead (center),<br />

104 Co-Chief <strong>Department</strong> <strong>of</strong> the Division <strong>of</strong> <strong>Medicine</strong> <strong>of</strong> Hematology and Medical Oncology.<br />

Annual Report 2011 1


Creating<br />

New Beginnings Out <strong>of</strong> Chaos<br />

Dr. Jean W. Pape: An Ongoing Journey, A Distinguished Career<br />

Dr. Pape is smiling because he just received an email from<br />

Vincent, a Lieutenant with the US Army 82nd Airborne Division.<br />

“Vincent and his platoon were attached to GHESKIO following<br />

the earthquake in Haiti. I gave him a plaque to thank him for his<br />

service,” explains Dr. Pape. “He’s a very nice and humane person<br />

who really helped us.” Completing the loop, Dr. Pape forwards<br />

Vincent’s email to Dr. Eric Goosby, the US Global AIDS Ambassador<br />

who facilitated the 82nd Airborne’s assistance in supporting<br />

GHESKIO’s post-earthquake field hospital.<br />

Anyone who has followed Dr. Pape’s career since his early days at<br />

<strong>Weill</strong> <strong>Cornell</strong> – four decades ago – knows that he has a knack for enlisting<br />

support and can create a functional operation out <strong>of</strong> chaos. Working in Haiti,<br />

the poorest country in the Western Hemisphere, he has faced epidemics<br />

<strong>of</strong> HIV/AIDS, tuberculosis, and cholera; high magnitude earthquakes resulting<br />

in the “worst injuries” he has “ever seen in his life”; hurricanes; floods;<br />

22 different changes in the Haitian government between 1986 and 2010;<br />

malnutrition; and gender violence.<br />

On the recent cholera outbreak, he affirms: “We were ready for this one<br />

because <strong>of</strong> our experience at GHESKIO in managing and treating the spread<br />

<strong>of</strong> HIV-AIDS. Preventing and treating this will be a huge undertaking. We will<br />

need – clean water, 200,000 gallons per day for 40,000 families, at least<br />

100 centers for rehydration, a patient education campaign, sanitation – four<br />

very important components. But, we’ll do it.”<br />

From “day one” Dr. Pape, Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong>, WCMC, knew that he would<br />

return to Haiti. He has since traveled a global journey <strong>of</strong> progress and credits<br />

<strong>Weill</strong> <strong>Cornell</strong> for providing the launching pad. “One <strong>of</strong> the greatest reasons I like<br />

<strong>Cornell</strong> is the interview I had for medical school. I had been told by my college<br />

advisor at Columbia that they will never accept you if you tell them you want to<br />

go back to Haiti. There were fewer slots for physicians at that time. Most <strong>of</strong> those<br />

had to go to U.S. physicians.<br />

So, I went for my interview at <strong>Cornell</strong>. They told me right away that they liked<br />

me, but they had one question: Do you plan to go back? I said yes. They looked<br />

at each other and went outside <strong>of</strong> the room. Well, that’s when I knew – that’s<br />

what I should not have said. Then they came back and told me: We heard you,<br />

we understand you want to go back to help, and we will not hold this against<br />

you. If you want to come here, we’ll accept you. A very nice interview.”<br />

Dr. Pape was also dedicated to improving the political future <strong>of</strong> Haiti,<br />

which had experienced 30 years <strong>of</strong> dictatorship from 1957 to 1986. Former<br />

Dean <strong>of</strong> Student Affairs, Cuban-born Dr. Charles Santos-Buch, asked to<br />

meet with Dr. Pape and advised: You seek “two very important things” –<br />

Dr. Pape with Lt. Mullen and Dr. Marie Marcelle Deschamps<br />

From Lt. Vincent Mullen, 82nd Airborne:<br />

“Dr. Pape,Congratulations on receiving the Gates<br />

Award and the Clinton Global Citizen Award. I don’t<br />

think they could have picked a better man, faculty, and<br />

organization to award such high accolades. First, it was<br />

the earthquake, then cholera, and finally Hurricane<br />

Tomas. These are trying times for Haiti, but I have no<br />

doubt in my mind that all <strong>of</strong> you will endure, especially<br />

with people like the GHESKIO team to lead. I see you<br />

have set up cholera treatment centers across Haiti.<br />

I wish only that I was there to help … still have these<br />

soccer balls and would like to send if it would not be<br />

a big inconvenience … just let me know the best<br />

way to send them.”<br />

“We heard you, we understand<br />

you want to go back to help ...<br />

we’ll accept you. A very nice<br />

interview.“<br />

2 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 3


Bittersweet,<br />

the earthquake<br />

brought mammoth<br />

destruction, but<br />

also served as<br />

a catalyst for<br />

positive change.<br />

“We showed in<br />

a study that<br />

those who were<br />

wasted became<br />

normal. We<br />

were able to<br />

stop it in time.”<br />

one studying medicine and the other being<br />

a revolutionary – but you cannot do both and will<br />

have to choose. “If you really want to help your<br />

people,” he said, “you have to learn and become<br />

the best physician you can be.” Dr. James Curtis,<br />

former Dean <strong>of</strong> Minority Students, also gave support:<br />

“You should always go back to your community and<br />

never forget where you came from and do good<br />

there.” For Dr. Pape, this experience was “very very<br />

powerful” causing him “to focus” on being the best<br />

physician he could be.<br />

He began working in the laboratory <strong>of</strong> Dr. Warren<br />

Johnson, Jr., B. H. Kean Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong>,<br />

WCMC, his medical school advisor and former chief<br />

<strong>of</strong> infectious diseases, while preparing to return<br />

to Haiti. “Working with Warren has been amazing.<br />

He’s been my advisor, collaborator, friend. I know<br />

his family well and he knows mine. We started with<br />

Warren here and myself in Haiti. In a very small<br />

program, I studied infantile diarrhea.” This small<br />

study <strong>of</strong> infantile diarrhea led to Dr. Pape’s landmark<br />

paper in The New England Journal <strong>of</strong> <strong>Medicine</strong>,<br />

for which he is credited with the recognition and<br />

first comprehensive description <strong>of</strong> AIDS in the<br />

developing world.<br />

In 1982, with a staff <strong>of</strong> two, Dr. Pape and<br />

Dr. Johnson established the HIV-AIDS research<br />

and treatment center, GHESKIO, which by 2010<br />

has treated hundreds <strong>of</strong> thousands <strong>of</strong> patients.<br />

Dr. Pape introduced oral rehydration in Haiti,<br />

ultimately decreasing infant mortality by 50%. He<br />

and his team had created a treatment model, using<br />

the <strong>Cornell</strong> unit at GHESKIO and mobile units as<br />

a training base –14,000 healthcare workers were<br />

trained. In 2003, the Haitian government asked the<br />

team to extend AIDS treatment nationally. “So, we<br />

did it. It is exactly the same model we used for the<br />

children with diarrhea and dehydration – a model<br />

oriented towards prevention, patient care, centered<br />

around the family. We now work at 22 sites across<br />

Haiti; 52% <strong>of</strong> all patients in Haiti receiving antiviral<br />

therapy, about 16,000, receive it through our<br />

network.” GHESKIO has developed breakthrough<br />

antiviral therapy and investigated the use <strong>of</strong> vaccines;<br />

recently, Dr. Daniel Fitzgerald, Associate Pr<strong>of</strong>essor <strong>of</strong><br />

<strong>Medicine</strong>, WCMC, and the team published research<br />

that changed the World Health Organization guidelines<br />

for the treatment <strong>of</strong> HIV-AIDS.<br />

With continuous funding from the NIH since 1983,<br />

GHESKIO has expanded its work in HIV-AIDS, and<br />

is now pursuing tuberculosis and cervical cancer, the<br />

major cancer in Haitian women.<br />

Just as GHESKIO was reaping the benefits <strong>of</strong><br />

decades <strong>of</strong> work, a natural disaster loomed. Haiti<br />

would be struck by a 7.0 magnitude earthquake<br />

on January 12, 2010. Bittersweet, the earthquake<br />

brought mammoth destruction, but also served<br />

as a catalyst for positive change.<br />

“The earthquake presented a lot <strong>of</strong> challenges,”<br />

says Dr. Pape, “as well as opportunities. Seven<br />

thousand people spontaneously landed on the<br />

doorstep <strong>of</strong> GHESKIO. For 15 years I had tried to find<br />

a partner to work in the slums <strong>of</strong> Port-au-Prince to<br />

help me build a better life for these people. They live<br />

across the street from GHESKIO (250,000 persons) in<br />

two large slums called, ironically, the City <strong>of</strong> God and<br />

the City <strong>of</strong> Eternity. They lead miserable lives because<br />

there is no work, they are subject to gangs, and do<br />

not have adequate food, housing or education. Now<br />

they had come to us. They had no choice.”<br />

With assistance from the Clinton Bush Fund,<br />

among other sources, Dr. Pape and his team built<br />

a tent-city for the 7,000 displaced persons. The<br />

tents stood on a soccer field, muddy from the rainy<br />

season. The solution was to obtain a piece <strong>of</strong> land<br />

from the Haitian president. “We got a piece <strong>of</strong> land<br />

and prepared the place. We drained it and moved it<br />

to above street level – so it doesn’t flood.” Medical<br />

care, food, and shelter are provided, while GHESKIO<br />

continues to treat patients with antiretroviral<br />

treatment for HIV-AIDS. Dr. Pape thanks the Clinton<br />

Bush Fund for its swift action and “flexibility.”<br />

Dr. Pape is now implementing a long list <strong>of</strong><br />

improvements. Experienced in treating horrendous<br />

earthquake injuries, what started as a field hospital<br />

is now a rehabilitation center. “The rehab center<br />

is functioning very well with 1,200 patients being<br />

followed and we’re training many people to become<br />

physical therapists.” A tent-city committee <strong>of</strong> 15<br />

people has been assembled. Dr. Pape insisted that<br />

four women be included: “To include women on the<br />

committee is the only way we can eliminate gender<br />

Rebecca Heidkamp (PhD candidate at the <strong>Cornell</strong> University-<br />

Ithaca, Division <strong>of</strong> Nutrition), Dr. Marie Marcelle Deschamps<br />

(GHESKIO), Dr. Pape<br />

“Dr. Pape’s integrity makes him someone I aspire to model<br />

my life vision and character after.”<br />

– Rebecca<br />

violence.” An increase in the number <strong>of</strong> rapes<br />

<strong>of</strong> young women occurred after the earthquake.<br />

Including women on the committee, along with Solar<br />

Lights in the camp to improve safety at night, has<br />

curbed the problem. “Just two little things like that<br />

– not complicated, not rocket science.” GHESKIO<br />

also created a rape crisis center where women are<br />

encouraged to report rape and be tested for HIV-AIDS.<br />

“Now the next move is to create a Global Village,”<br />

says Dr. Pape. “We’ve partnered with <strong>Cornell</strong><br />

University and have received enormous support from<br />

the BioMerieux Foundation in France. The idea is that<br />

everybody will do what they do best – engineers,<br />

teachers, and more.” A school currently exists at<br />

GHESKIO, but “the kids are sitting in classrooms that<br />

are not ideal.” With support from the Principality<br />

<strong>of</strong> Monaco, GHESKIO is taking education to the<br />

next level. A new school, to be called the Prince<br />

Albert <strong>of</strong> Monaco School, will upgrade facilities and<br />

organization <strong>of</strong> programs. “This will be a real school.”<br />

Peanuts? Peanut butter – rich in protein and<br />

made in Haiti – turns out to be the solution to<br />

another problem – malnutrition in children. GHESKIO<br />

has received one million dollars from the MAC AIDS<br />

Fund to create a nutrition center. “We started out<br />

creating a club for mothers, an interesting idea, not<br />

from me but from Rebecca Heidkamp, an Ithaca<br />

PhD candidate.” Ms. Heidkamp explains: “We call<br />

it the Caregivers Club, as there are mothers, dads,<br />

and other caregivers. I developed the initial plan and<br />

drew heavily on what I’ve learned from my mentors<br />

in <strong>Cornell</strong> University’s Division <strong>of</strong> Nutritional Sciences.<br />

We deliver preventive health services and nutrition<br />

support for children under two, through a clubbased<br />

model to improve clinical health outcomes and<br />

empowerment for GHESKIO parents.” In urban Haiti,<br />

children under two are at highest risk <strong>of</strong> malnutrition<br />

and mortality due to infectious diseases. More than<br />

one-third <strong>of</strong> child deaths due to these conditions are<br />

preventable with simple interventions, such as clean<br />

water, nutritional supplements and vaccinations.<br />

By giving children “manba fotifye” (between<br />

6 and 11 months) reversal <strong>of</strong> two major nutrition<br />

outcomes has been achieved: stunting and wasting.<br />

Dr. Pape Receives Clinton Global Citizen Award<br />

A recipient <strong>of</strong> the French Legion <strong>of</strong> Honor Award and the 2010 Gates Award for Global Health,<br />

Dr. Jean W. Pape was honored with the Clinton Global Citizen Award on September 23, 2010 in<br />

a ceremony televised on CNBC. Established by President William J. Clinton and the Clinton Global<br />

Initiative in 2007, the award recognizes individuals who have championed innovative solutions<br />

to pressing global problems. President Clinton introduced Dr. Pape, stating, “Your dedication<br />

to helping Haitians develop their public health system stands as a testament to your visionary<br />

leadership. For nearly 30 years, you’ve set an outstanding example through your work on primary<br />

care and integrated HIV-AIDS treatment in Haiti. In addition, your work in emergency care since<br />

the devastating earthquake has been tremendous.”<br />

“We showed in a study that those who were wasted<br />

became normal. We were able to stop it in time,”<br />

Dr. Pape reports. “Manba fotifye” in Haitian Creole<br />

means fortified peanut butter – it has its own song.<br />

Utilizing a new concept called “photo<br />

sensitization,” mothers are given disposable cameras<br />

and asked to take photos <strong>of</strong> their environment, good<br />

or bad images, then explore what the images mean<br />

to them and their family’s future. “You empower<br />

them so they are not passive. They are being actors to<br />

change the environment.” And the team is working<br />

on a “Good Habitat” project: “We are building a<br />

school to teach people how to be carpenters and<br />

masons. These are the same people who will build<br />

their own Global Village; they will have a vested<br />

interest. You give them tools for a business – the<br />

construction business is a booming industry.”<br />

In late 2010, an outbreak <strong>of</strong> cholera emerged in<br />

Haiti. Dr. Macarthur Charles, one <strong>of</strong> a cadre <strong>of</strong> young<br />

physicians with GHESKIO who trained in the <strong>Weill</strong><br />

<strong>Cornell</strong> Division <strong>of</strong> Infectious Diseases, and currently<br />

an Assistant Pr<strong>of</strong>essor, WCMC, is heading one <strong>of</strong><br />

the cholera medical centers. “Dr. Charles has taken<br />

a lot <strong>of</strong> initiative with this,” says Dr. Pape. With help<br />

from UNICEF and other partners, Dr. Charles, set to<br />

work treating patients the week the outbreak began.<br />

Doctors Without Borders had called at that time<br />

asking for help, as their treatment tents were being<br />

blown apart by hurricane winds. There are special<br />

concerns in the slums because <strong>of</strong> lack <strong>of</strong> clean water.<br />

Drs. Pape and Charles will work with the government<br />

to formulate a plan to make clean water available<br />

to the communities.<br />

Dr. Pape’s work – step by step – has led to a new<br />

beginning for Haiti. Guiding a new generation <strong>of</strong><br />

physicians and researchers, providing life-saving<br />

treatments that impact world health, and forming<br />

dynamic collaborations across the globe distinguish<br />

his career. These advancements are culminating in<br />

a dream realized – a Global Village where people can<br />

live in better health, share an improved quality <strong>of</strong> life,<br />

and receive the tools they need to determine their<br />

own future.<br />

“We’ve partnered<br />

with <strong>Cornell</strong><br />

University and<br />

have received<br />

enormous<br />

support from<br />

the BioMerieux<br />

Foundation in<br />

France. The idea is<br />

that everybody will<br />

do what they do<br />

best – engineers,<br />

teachers, and<br />

more.”<br />

4 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 5


Building<br />

a Defense Against Resistance: Hospital-acquired Infections<br />

Hospital-acquired infections can result from numerous different factors, and the relative contribution <strong>of</strong> each<br />

depends largely on the type <strong>of</strong> infection. Certain infections are caused by the insertion <strong>of</strong> medical devices into the<br />

body, which interrupts a patient’s normal defense mechanisms and provides bacteria greater-than-usual access.<br />

Germ in the Machine?<br />

Examples include ventilator-associated<br />

pneumonias, central line-associated bloodstream<br />

infections (caused by catheters inserted into<br />

the large veins <strong>of</strong> the neck, chest or groin) and<br />

catheter-associated urinary tract infections.<br />

Particular surgeries and procedures add their own<br />

additional risk factors. For example, bone marrow,<br />

Dr. Wilson envisions a future when computers will be a more integral part <strong>of</strong><br />

infection control. A geographic information system could one day be used<br />

to configure a three-dimensional model <strong>of</strong> the hospital that could then be<br />

populated with data collected by the infection control team to display current<br />

infections in every unit <strong>of</strong> the hospital, along with what types <strong>of</strong> bacteria are<br />

there and when each first appeared.<br />

“A picture is worth a thousand words, and such a system could quickly<br />

produce short-term as well as longitudinal analyses <strong>of</strong> the pattern <strong>of</strong> spread<br />

<strong>of</strong> infections. It’s a far more advanced system than most hospitals have, but<br />

geographic information systems are used to analyze and solve problems in<br />

many other industries. This is the future <strong>of</strong> hospital epidemiology, and it’s<br />

very exciting.”<br />

stem cell and solid organ transplant surgeries can<br />

compromise the patients’ immune systems, leading<br />

to a further increased risk <strong>of</strong> infection.<br />

For reasons that are not entirely understood, but<br />

perhaps due in part to high population density and<br />

world travel, hospitals in the Northeast <strong>of</strong>ten see the<br />

first outbreaks <strong>of</strong> new pathogens – or old pathogens<br />

with new antibiotic resistance patterns – before they<br />

spread to the rest <strong>of</strong> the country. In any hospital,<br />

however, infection risk can be compounded by many<br />

factors, including hand hygiene among healthcare<br />

staff; thoroughness <strong>of</strong> environmental cleaning and<br />

laundry service; and antibiotic use and misuse.<br />

Hospital visitors, though healthy, may unknowingly<br />

bring with them any number <strong>of</strong> harmful microbes<br />

that can then spread to patients. And patient age<br />

can be a factor, as both young and elderly patients<br />

usually have more delicate immune systems.<br />

There is also the issue <strong>of</strong> bacterial resistance. The<br />

appearance within the last decade <strong>of</strong> a class <strong>of</strong> superresistant<br />

bacteria that survive every known antibiotic<br />

means that prevention is now more essential<br />

than ever. As David P. Calfee, MD, MS, NewYork-<br />

Presbyterian’s new Chief Hospital Epidemiologist,<br />

explains, drug-resistant strains <strong>of</strong> bacteria can<br />

emerge periodically in everyday life, but in hospitals,<br />

they can exhibit a kind <strong>of</strong> Darwinian selection on<br />

overdrive. A patient may be prescribed a broadspectrum<br />

antibiotic that kills <strong>of</strong>f a large proportion <strong>of</strong><br />

the bacteria, but if some <strong>of</strong> the remaining bacteria<br />

are resistant to that antibiotic, the spread <strong>of</strong> those<br />

organisms is actually accelerated.<br />

Infection prevention and control, as a field <strong>of</strong><br />

study, began in the late 1960s, as more and more<br />

hospitals opened intensive care units and physicians<br />

made the connection between intensive use <strong>of</strong> lifesustaining<br />

equipment and unforeseen infections.<br />

In 1970, Lewis M. Drusin, MD, MPH, <strong>Department</strong><br />

<strong>of</strong> <strong>Medicine</strong>, became the college’s first hospital<br />

epidemiologist, a position he held for 40 years.<br />

Today, hospital epidemiologist Stephen J. Wilson,<br />

MD, MPH – another new <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

recruit – works with Dr. Calfee and five infection<br />

control nurses to monitor infections that occur in<br />

the hospital, analyzing which microbes are present,<br />

when and where, how they appeared, and where<br />

they may show up next. Drs. Calfee and Wilson also<br />

participate in the hospital’s antibiotic stewardship<br />

program, evaluating and reevaluating antibiotic<br />

prescriptions for hospital patients, to make informed<br />

decisions about the best use <strong>of</strong> antibiotics that will<br />

help curb the growth and spread <strong>of</strong> resistant strains<br />

<strong>of</strong> bacteria. “You don’t want to give a two-week<br />

course <strong>of</strong> antibiotics if the patient’s illness only<br />

requires a one-week course,” says Dr. Calfee. “<br />

Or if you empirically prescribe a broad-spectrum<br />

antibiotic and then the patient’s culture comes<br />

back positive for a bacterium that is susceptible to<br />

a variety <strong>of</strong> antibiotics, it’s usually best to switch<br />

to a more narrow-spectrum antibiotic.”<br />

Drs. Calfee and Wilson are also developing formal<br />

hospital epidemiology training for the Infectious<br />

Diseases Fellowship Program. Infection control<br />

training initiatives will include medical students,<br />

residents, faculty and staff. “While many infectious<br />

diseases programs have the ability to train fellows<br />

in hospital epidemiology, we are hoping to become<br />

one <strong>of</strong> the few that <strong>of</strong>fers this as a formal track with<br />

the master’s degree work seamlessly integrated into<br />

the fellowship years,” says Dr. Wilson.<br />

Drs. Calfee and Wilson are exploring numerous<br />

research and patient safety initiatives, in collaboration<br />

with sister institutions (including <strong>Cornell</strong> University,<br />

Ithaca, Memorial Sloan-Kettering Cancer Center, The<br />

Rockefeller University and the Hospital for Special<br />

Surgery) to investigate device-associated infections,<br />

surgical site infections, information technology and<br />

super-resistant bacteria. They are also developing<br />

ideas in less traditional avenues including a project<br />

with the <strong>Weill</strong> <strong>Cornell</strong> <strong>Department</strong> <strong>of</strong> Public Health<br />

on how to mathematically model various hospital<br />

infection control scenarios in search <strong>of</strong> new solutions.<br />

Preliminary discussions with microbiologists at<br />

the <strong>Cornell</strong> College <strong>of</strong> Veterinary <strong>Medicine</strong> focus<br />

on antibiotic resistance across the spectrum <strong>of</strong><br />

agricultural and human use <strong>of</strong> antibiotics.<br />

“The questions that are out there waiting to be taken up – along<br />

with the technology now available to address them – provide<br />

innumerable opportunities for research that can directly affect<br />

the health not just <strong>of</strong> hospital patients, but <strong>of</strong> the public,” says<br />

Dr. Wilson. “We intend to keep <strong>Weill</strong> <strong>Cornell</strong> at the leading<br />

edge <strong>of</strong> this frontier.”<br />

NewYork-Presbyterian Hospital has a long<br />

record <strong>of</strong> relatively low infection rates compared<br />

to other hospitals in the state.<br />

Research conducted by Dr. Wilson* showed that infection control is good for<br />

the financial health <strong>of</strong> a medical center. Adjusting for severity <strong>of</strong> illness, length<br />

<strong>of</strong> hospital stay and other variables, the average direct cost to the hospital <strong>of</strong><br />

a single Acinetobacter baumannii infection in the burn unit was over $98,000 per<br />

hospitalization. *American Journal <strong>of</strong> Infection Control, 2004<br />

6 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

Dr. Stephen Wilson (L) Dr. David Calfee (R)<br />

Annual Report 2011 7


Promoting<br />

Better Sleep for Better Overall Health…<br />

The <strong>Weill</strong> <strong>Cornell</strong> Center for Sleep <strong>Medicine</strong> Opens<br />

Nine thousand square feet dedicated to a good night’s sleep …<br />

Newly renovated and relocated, the <strong>Weill</strong> <strong>Cornell</strong> Center for Sleep <strong>Medicine</strong> opened its doors in March<br />

<strong>of</strong> 2010. Scheduling 100 patients per week for one <strong>of</strong> the nation’s leading health problems – lack <strong>of</strong> normal<br />

sleep – Medical Director, Ana Krieger, MD (<strong>Medicine</strong>) and Co-Director, Arthur Spielman, PhD (Neurology),<br />

are diagnosing and treating patients from all walks <strong>of</strong> life. Patients include truck drivers, assembly line<br />

workers, Wall Street employees, politicians, celebrities, the elderly, and babies too. The Center <strong>of</strong>fers a<br />

multidisciplinary team <strong>of</strong> experts, a high-tech control room, sound-pro<strong>of</strong>ed accommodations designed with<br />

comfort in mind, sweeping views <strong>of</strong> New York City, and convenient on-site parking.<br />

“Sleep is a vital physical function for the body,” says Dr. Krieger. “The most frequent question we are<br />

asked is how many hours <strong>of</strong> sleep does a person need to function well. There’s no exact answer to that.<br />

Some people think they are functioning on a very short amount <strong>of</strong> sleep, but when we investigate, we<br />

usually see that the person perceives their state <strong>of</strong> sleep as being much shorter than it really is. It’s very<br />

individualized and personal. A host <strong>of</strong> health issues, stress, poor eating habits, medications, genetics and<br />

other factors, may be interfering with sound sleep. ”<br />

Lack <strong>of</strong> sleep, or poor sleep, has been linked as a contributor to a long list <strong>of</strong> negative health outcomes:<br />

cardiovascular disease, stroke, the worldwide obesity epidemic, and even a person’s longevity. Effective<br />

treatment requires a multidisciplinary team to uncover the exact cause <strong>of</strong> a sleep disorder. The Center’s<br />

team provides the expertise <strong>of</strong> many: sleep medicine specialists, and consultants in neurology, internal<br />

medicine, pulmonary medicine, ENT (ear, nose and<br />

throat ), pediatrics, psychiatry, psychology, bariatric<br />

surgery, cardiology, endocrinology, and nutrition.<br />

Sophisticated tools allow for the diagnosis <strong>of</strong> the full<br />

spectrum <strong>of</strong> sleep disorders, including sleep apnea<br />

(sleep-disordered breathing), restless legs syndrome,<br />

narcolepsy, parasomnias, circadian rhythm sleep<br />

disorders, excessive sleepiness, and insomnia.<br />

“The initial evaluation we use is non-invasive,”<br />

explains Dr. Spielman, a leading authority in<br />

the field <strong>of</strong> insomnia. “We understand that it’s<br />

important that the patient be able to trust their<br />

environment as we’re monitoring their sleep. Any<br />

fears or concerns a patient may have are addressed<br />

immediately. Polysomnography, a study performed<br />

overnight or during the daytime, is employed using<br />

non-invasive electrodes placed on the patient’s<br />

skin and scalp to monitor changes in brain activity,<br />

respiration, oxygen levels, heart rhythm and muscle<br />

activity. This monitoring may be a little annoying at<br />

first, but we find it does not actually interfere with<br />

the patient falling asleep.”<br />

“Lack <strong>of</strong> sleep predisposes the body to a certain<br />

type <strong>of</strong> inflammatory response,” according to<br />

Dr. Krieger. “We know there are systemic<br />

manifestations going on throughout the body<br />

due to lack <strong>of</strong> sleep. It is known that sleep<br />

apnea, involving a breathing disorder, creates an<br />

inflammatory response in the body that also affects<br />

the circulation. We see sleep apnea affecting the<br />

blood vessels. The vessels can close down, thrombosis<br />

may occur and impaired blood supply (ischemia) to<br />

areas <strong>of</strong> the body may develop. This can be a major<br />

concern if it affects brain function. Even a little<br />

bit <strong>of</strong> ischemia in the brain can cause significant<br />

neurological changes. Many studies have shown that<br />

leaving sleep apnea untreated can lead to stroke,<br />

other cardiovascular manifestations, and increased<br />

morbidity and mortality. But once patients with sleep<br />

apnea are treated, things get pretty close to normal.”<br />

A head mask to provide continuous positive<br />

airway pressures during sleep is <strong>of</strong>ten prescribed as<br />

the remedy for sleep apnea. “Masks are afforded<br />

in lots <strong>of</strong> different types for the patient’s comfort:<br />

over the nose, in the nose, around the face,” says<br />

Dr. Spielman. “The patient selects from<br />

one <strong>of</strong> many styles,” adds Dr. Krieger, and<br />

airway pressures are continually adjusted for<br />

personalized need as determined by the results<br />

<strong>of</strong> the sleep study.<br />

At the forefront <strong>of</strong> research in the relatively<br />

new field <strong>of</strong> sleep medicine, Dr. Krieger is taking<br />

a “mechanistic approach” to sleep apnea with<br />

funding from the National Institutes <strong>of</strong> Health.<br />

“We are researching the low oxygen levels at<br />

night and its effect on vascular function. We<br />

are asking what happens to the walls <strong>of</strong> blood<br />

vessels, the so-called endothelial cells. What<br />

happens to blood platelets which are supposed to<br />

coagulate the blood only when needed? Are they<br />

hyperfunctioning, being inappropriately activated<br />

because <strong>of</strong> inadequate sleep? We are trying to<br />

make that bridge in the mechanism to see how<br />

we can decrease this hemostatic and inflammatory<br />

response. Perhaps, we could give some patients<br />

something as simple as aspirin. Is giving a patient<br />

a mask with CPAP (continuous positive airway<br />

pressure) enough for the best treatment? Or could<br />

giving them a medicine ‘X’ ameliorate the overall<br />

inflammatory response effectively?”<br />

Combining expertise, in this collaborative<br />

initiative between the <strong>Department</strong>s <strong>of</strong> <strong>Medicine</strong><br />

and Neurology, Drs. Spielman and Krieger are<br />

melding front-line research with top-line patient<br />

care. Dr. Spielman, who had served as director<br />

<strong>of</strong> the sleep center at another location, says,<br />

“We were fortunate indeed to have recruited Ana.<br />

She is the original renaissance woman. She has<br />

truly raised the standards for everyone at the sleep<br />

center.” Dr. Krieger adds, “Everyone respects<br />

Art so much. He’s a world authority in the field.<br />

I always had the ‘Dr. Spielman’ slides on insomnia<br />

in my presentations.”<br />

Poised to enter a breakthrough era in the<br />

understanding and treatment <strong>of</strong> sleep disorders,<br />

Co-Directors Krieger and Spielman have established<br />

a premier partnership at the <strong>Weill</strong> <strong>Cornell</strong> Center<br />

for Sleep <strong>Medicine</strong> that will help patients achieve<br />

a good night’s sleep and better health for many<br />

years to come.<br />

“The next step<br />

in sleep<br />

medicine<br />

research will<br />

be clinical<br />

trials,” affirms<br />

Dr. Krieger.<br />

Left to Right:<br />

Arthur Spielman, PhD;<br />

Amit Patel, MD;<br />

Nitin Sethi, M.B. B.S.;<br />

Ana Krieger, MD, MS;<br />

Alan Segal, MD;<br />

and Matthew Ebben, PhD<br />

8 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

Annual Report 2011 9


Establishing<br />

Hospital <strong>Medicine</strong>: A New System Within the System<br />

Hospital <strong>Medicine</strong> – providing specialized medical care to hospitalized patients – is the<br />

fastest-growing specialty in the history <strong>of</strong> American medicine. The number <strong>of</strong> physicians<br />

(“hospitalists”) engaged in this specialty has increased over 30-fold since 1997.<br />

Hospitalists now have an established presence<br />

across the United States at hospitals large and small,<br />

teaching and non-teaching. This sudden growth<br />

suggests that hospitalists are successfully addressing<br />

three pervasive and interrelated needs: the needs<br />

<strong>of</strong> individual patients, the needs <strong>of</strong> primary care<br />

physicians, and the needs <strong>of</strong> hospitals. These needs<br />

are interrelated because they share the common<br />

objective <strong>of</strong> improved health outcomes. Hospitalists<br />

meet those needs by not only providing timely<br />

effective and efficient clinical care but also by leading<br />

efforts to improve services within the hospital. This<br />

requires skills not typically taught at most medical<br />

schools. In their role as clinician-investigators and<br />

clinician-leaders, they are asked to design and test<br />

targeted interventions to improve the processes and<br />

outcomes <strong>of</strong> hospital care, for example, preventing<br />

unnecessary returns to the hospital, sparing patients<br />

another round <strong>of</strong> bills and saving hospitals billions<br />

<strong>of</strong> dollars each year.<br />

“There are three forces behind hospital medicine:<br />

quality, costs, and education,” explains Dr. Arthur<br />

T. Evans. “Hospitalists are leading the effort to<br />

improve systems <strong>of</strong> inpatient care, increase safety,<br />

reduce waste and unnecessary costs, and teach<br />

“Hospitalists are leading the effort to improve<br />

systems <strong>of</strong> inpatient care, increase safety, reduce<br />

waste and unnecessary costs, and teach the next<br />

generation <strong>of</strong> physicians advanced clinical skills.”<br />

the next generation <strong>of</strong> physicians advanced clinical<br />

skills. Because their practice is focused solely on<br />

the inpatient setting, hospitalists have an intimate<br />

knowledge <strong>of</strong> the complex workings <strong>of</strong> the hospital<br />

and understand how to work the system to maximize<br />

their patients’ wellbeing. Hospital administrators<br />

also benefit from this intimate knowledge, because<br />

to improve a hospital’s systems <strong>of</strong> care you need<br />

people who are spending most <strong>of</strong> their time inside<br />

the hospital and who are totally invested.”<br />

Recruited in 2009, Dr. Evans, Chief <strong>of</strong> Hospital<br />

<strong>Medicine</strong> and Vice Chair for Faculty Development,<br />

launched the <strong>Department</strong>’s new Division <strong>of</strong> Hospital<br />

<strong>Medicine</strong> with 10 hospitalists on board. As <strong>of</strong> 2010,<br />

the Division has grown to 21 faculty members<br />

responsible for the daily care <strong>of</strong> 125 inpatients. Nine<br />

<strong>of</strong> the faculty have advanced training in specialized<br />

fields <strong>of</strong> medicine, including infectious diseases,<br />

medical informatics, nephrology, emergency<br />

medicine, geriatrics, critical care, and medical ethics.<br />

Two <strong>of</strong> the faculty are “nocturnists,” working<br />

only nights to care for critically ill patients on the<br />

Leukemia and Bone Marrow Transplant services.<br />

Because <strong>of</strong> the group’s collective expertise in<br />

medical informatics, the Division has been able to<br />

use the hospital’s electronic medical record system<br />

to measure and track improvements in patient<br />

safety and quality <strong>of</strong> care. For example, one project<br />

is identifying the factors that predict hospital<br />

readmission within 30 days. Other ongoing projects<br />

include using evidence-based guidelines to better<br />

control pain in the hospital and optimize care for<br />

a wide range <strong>of</strong> conditions, from pneumonia, heart<br />

failure and s<strong>of</strong>t tissue infections, to alcohol and<br />

narcotic withdrawal.<br />

Studies indicate that hospitalists in America are<br />

helping to reduce overall hospital costs by up to<br />

20 percent and are reducing the average length <strong>of</strong><br />

hospital stays by up to 30 percent. Although reducing<br />

costs is important, the major goal is improving<br />

quality and safety. Reducing waste, however, can<br />

accomplish both goals. Some studies also suggest<br />

that hospitalists can lower mortality rates, decrease<br />

readmissions, and improve resident training.<br />

“Seventy-five percent <strong>of</strong> our time is working with<br />

and teaching residents,” says Dr. Evans. “Hospitalists<br />

advance the academic mission at <strong>Weill</strong> <strong>Cornell</strong><br />

by demonstrating best-practice in the care <strong>of</strong> the<br />

hospitalized patient and by coaching students and<br />

residents in the interpersonal, communication,<br />

clinical reasoning, and technical skills that define<br />

good doctoring.”<br />

How did the hospitalist movement evolve?<br />

Beginning in the 1990s, primary care physicians,<br />

who once visited hospitals regularly to care for their<br />

hospitalized patients, were facing bourgeoning case<br />

loads that tied them to the outpatient setting. In turn,<br />

their patients who required hospitalization were now<br />

more acutely ill, more complex, and more in need <strong>of</strong><br />

intensive care than in years past. At the same time,<br />

hospitals themselves had become more complicated,<br />

with time-consuming mazes <strong>of</strong> processes that were<br />

increasingly difficult for a physician outside the<br />

system to navigate. So the hospitalist emerged –<br />

an on-site, continuously available physician, wellversed<br />

in hospital technology, procedures, high-quality<br />

acute care, and up-to-date clinical decision-making.<br />

“The skilled hospitalist will involve the patient’s<br />

primary care physician as an integral part <strong>of</strong> the<br />

team,” emphasizes Dr. Evans. “We recognize that<br />

we don’t know the patient as well as the patient’s<br />

primary care physician. This is an ongoing challenge<br />

that hasn’t quite been ironed out. Another<br />

challenge is meeting the growing need to build and<br />

lead teams within the hospital to improve systems<br />

<strong>of</strong> care. The necessary leadership and management<br />

skills are not taught in most medical schools or<br />

residency programs. Therefore, there is a continuous<br />

need to train hospitalists in these crucially important<br />

nonclinical skills.”<br />

The Division <strong>of</strong> Hospital <strong>Medicine</strong> is meeting<br />

these challenges by strengthening ties with<br />

primary care physicians, building relationships with<br />

community resources, and developing innovative<br />

faculty mentorship programs.<br />

“When the patient is in the hospital, we will<br />

soon test the use <strong>of</strong> laptop computers with video<br />

capability to allow face-to-face communication<br />

over the Internet with the primary care physician or<br />

with the relative living across the country or on the<br />

other side <strong>of</strong> the world. We are also partnering with<br />

visiting nurse organizations. After discharge, for<br />

patients unable to see their primary care physician<br />

within the first week, we will work with a visiting<br />

nurse to assure the patient’s first days at home<br />

are safe and be available to make adjustments in<br />

treatments until their primary care physician can<br />

resume responsibility. A well-trained visiting nurse<br />

can be the doctor’s eyes and ears.”<br />

A newly established system within the system, the<br />

Division <strong>of</strong> Hospital <strong>Medicine</strong> in the <strong>Department</strong> <strong>of</strong><br />

<strong>Medicine</strong> at NYP/<strong>Weill</strong> <strong>Cornell</strong> is set to address the<br />

challenges that a new era in healthcare reform will<br />

undoubtedly present. The Division’s interdisciplinary<br />

approach, coupled with its faculty’s ease in using the<br />

hospital’s organizational and information systems,<br />

make them a uniquely qualified force in inpatient<br />

careand residency training. Their specialized mission to<br />

enhance value for patients in the hospital will involve<br />

a balance between negotiating the high-tech world<br />

<strong>of</strong> the modern hospital with the high-touch needs <strong>of</strong><br />

sick individuals who are at their most vulnerable.<br />

Dr. Sean Pickering (L) with<br />

Dr. Arthur Evans<br />

10 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 11


Advancing<br />

the Advance Trial<br />

Superior Viral Response Rates Using Telaprevir<br />

Dr. Ira M. Jacobson, Chief <strong>of</strong> Gastroenterology<br />

and Hepatology and the lead investigator <strong>of</strong><br />

the ADVANCE trial, reported breakthrough<br />

findings at the 61st Annual Meeting <strong>of</strong> the<br />

American Association for the Study <strong>of</strong> Liver<br />

Disease in Boston on November 2, 2010.<br />

Adding a protease inhibitor – telaprevir – to the<br />

standard first-time treatment given to patients infected<br />

with hepatitis C virus (HCV) resulted in a superior<br />

success rate in patients with genotype 1, the most<br />

common and most difficult-to-cure strain. In fact,<br />

75% <strong>of</strong> patients who received 12 weeks <strong>of</strong> therapy<br />

with telaprevir, in combination with the current<br />

standard drug treatment <strong>of</strong> peginterferon and ribavirin<br />

achieved a viral cure in this Phase 3 study compared<br />

with 44% <strong>of</strong> patients who received peginterferon and<br />

ribavirin alone. Telaprevir is now on the map as a new<br />

therapy that dramatically improves the treatment <strong>of</strong><br />

hepatitis C, a highly contagious blood borne disease<br />

which can progress to cirrhosis and liver cancer.<br />

Dr. Jacobson was a coauthor on a presentation at<br />

the same meeting showing that boceprevir, another<br />

protease inhibitor, is also associated with a highly<br />

significant improvement in viral cure rates.<br />

A Vision to Cure Hepatitis C, Before it had<br />

a Name<br />

A leader in the treatment <strong>of</strong> hepatitis B and C,<br />

Dr. Jacobson was already aggressively investigating<br />

antiviral therapies during the late 1980s and<br />

1990s. He has served as the Principal Investigator<br />

<strong>of</strong> numerous clinical trials, including the original<br />

studies done with interferon, as well as subsequent<br />

studies utilizing combination therapies <strong>of</strong> a new<br />

formulation <strong>of</strong> interferon, known as pegylated<br />

interferon, with ribavirin.<br />

“In the 1980s, I had a vision that I wanted<br />

to be on the cutting edge <strong>of</strong> what was then the<br />

barely nascent field <strong>of</strong> antiviral therapy for what<br />

we called non-A and non-B hepatitis, and which by<br />

1989, came to be called hepatitis C. When I started<br />

out, we didn’t actually have a name for what we<br />

were investigating. We knew, though, that a virus<br />

was causing this disease, via such routes as blood<br />

transfusions or sharing <strong>of</strong> needles, resulting in<br />

progressive liver damage.<br />

By 1999, Dr. Jacobson worked with NewYork-Presbyterian Hospital to expand<br />

the shared vision <strong>of</strong> “establishing a major clinical and scientific center for the<br />

treatment and investigation <strong>of</strong> hepatitis C towards achieving a cure.”<br />

(L to R) Drs. Andrew Talal, Ira Jacobson, Ype de Jong, Charles Rice<br />

The center represents a collaboration between <strong>Weill</strong> <strong>Cornell</strong><br />

Medical College, NewYork-Presbyterian Hospital, and The<br />

Rockefeller University, where Dr. Charles Rice, Adjunct Pr<strong>of</strong>essor,<br />

<strong>Weill</strong> <strong>Cornell</strong>, directs one <strong>of</strong> the world’s leading scientific<br />

laboratories dedicated to the study <strong>of</strong> hepatitis C virus.<br />

12 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

Annual Report 2011 13


Advancing the Advance Trial continued<br />

Dr. Reidenberg Receives ASPET’s Torald Sollmannn Award<br />

(American Society for Pharmacology and Experimental Therapeutics )<br />

Dr. Jacobson with Pete Pizzuti<br />

“I was what they call a partial responder to treatment,”<br />

says Pete Pizzuti. “But Dr. Jacboson was aggressive with<br />

my case and advised an increase in the number <strong>of</strong> imaging<br />

tests, from one to two per year. He also adjusted my<br />

medications. Because <strong>of</strong> the increased number <strong>of</strong> imaging<br />

tests, Dr. Jacobson caught my liver cancer in time. I couldn’t<br />

enter his trial, though, because I was a liver transplant<br />

candidate. He really listens to you and he guided me<br />

through the process, sending me to all the right doctors<br />

for the transplant. You are treated as more than a number<br />

here. There is real concern for the patient, concern for<br />

your life, and your quality <strong>of</strong> life. ”<br />

By 1999, Dr. Jacobson worked with NewYork-<br />

Presbyterian Hospital to expand the shared vision <strong>of</strong><br />

“establishing a major clinical and scientific center<br />

for the treatment and investigation <strong>of</strong> hepatitis<br />

C towards achieving a cure.” This vision became<br />

a reality with the opening <strong>of</strong> The Center for the<br />

Study <strong>of</strong> Hepatitis C in 2000, which today receives<br />

patients from around the world. The center is<br />

dedicated to a new era in the treatment <strong>of</strong> hepatitis<br />

C in which direct-acting antiviral drugs will play a<br />

central role. The Center also features a translational<br />

research program, directed by Dr. Andrew Talal,<br />

central to which is a database and large repository<br />

<strong>of</strong> patient-derived samples. The center represents<br />

a collaboration between <strong>Weill</strong> <strong>Cornell</strong> Medical<br />

College, New York Presbyterian Hospital, and<br />

The Rockefeller University, where Dr. Charles Rice,<br />

Adjunct Pr<strong>of</strong>essor, <strong>Weill</strong> <strong>Cornell</strong>, directs one <strong>of</strong> the<br />

world’s leading scientific laboratories dedicated to<br />

the study <strong>of</strong> hepatitis C virus.<br />

“We really do believe this virus is curable and<br />

you cannot say that in medicine about too many<br />

viruses. Some viruses, like hepatitis B and HIV, have<br />

ways <strong>of</strong> hiding out in cells, archiving themselves<br />

and embedding their genome deep inside <strong>of</strong> cells.<br />

Even if you suppress completely the virus’s ability<br />

to reproduce, it’s still there and may wake up some<br />

other time. But we think hepatitis C does not have<br />

that biological avenue. We’re not aware <strong>of</strong> an<br />

archival form which can remain dormant.”<br />

The Willing Participation <strong>of</strong> Patients and<br />

a Successful Clinical Trial<br />

“Most patients joining our trials have come from<br />

the faculty’s clinical practices. Patients are worried<br />

about what the cure rate is. What would make it<br />

worth it to them to embark on therapy? The biggest<br />

obstacle is fear <strong>of</strong> the unknown. Once they are over<br />

that hurdle and make the decision to be treated,<br />

they stick with it. A few must stop, mostly because<br />

<strong>of</strong> side effects from interferon or ribavirin. So, we’re<br />

not only dedicated to increasing the cure rate,<br />

we want to improve tolerability and reduce side<br />

effects.”<br />

A Quarter-Century Long Focus on Hepatitis and<br />

Liver Disease in the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

After twenty-five years <strong>of</strong> focused work in the<br />

field <strong>of</strong> hepatis C and liver disease, Dr. Jacobson<br />

played a role instrumental in the first liver transplant<br />

at NewYork-Presbyterian Hospital/<strong>Weill</strong> <strong>Cornell</strong><br />

Medical Center. “One <strong>of</strong> my patients became the<br />

first person to receive a liver transplant here,” says<br />

Dr. Jacobson.<br />

Currently coined “Personalized <strong>Medicine</strong>,” Dr. Marcus Reidenberg was already researching<br />

the field – defining it as “Individualized <strong>Medicine</strong>”– as early as the 1960s.<br />

He directed a course for the American College <strong>of</strong><br />

Physicians (1973) and prepared a book on the topic<br />

for The Medical Clinics <strong>of</strong> North America (1974).<br />

By 1972, he had assessed: “Clinical pharmacologists<br />

working in the area <strong>of</strong> individual differences in drug<br />

response have learned enough about the causes<br />

<strong>of</strong> these variations to make this information known<br />

to the practicing community.”<br />

A pioneer in many areas <strong>of</strong> clinical pharmacology<br />

– with more than 50 years as a physician-scientist<br />

continually pressing the boundaries <strong>of</strong> discovery –<br />

Dr. Reidenberg embodies the full meaning <strong>of</strong> the<br />

Torald Sollmann Award (ASPET), an award that<br />

honors “imaginative persons dedicated to hard<br />

work and self-development.” His advancements<br />

in pharmacology have directly benefited patients<br />

in the clinical setting. After preparing The Medical<br />

Clinics <strong>of</strong> North America book on “Individualization<br />

<strong>of</strong> Drug Therapy,” he directed another ACP course in<br />

1982, preparing a second Medical Clinics <strong>of</strong> North<br />

America book, “Clinical Pharmacology <strong>of</strong> Symptom<br />

Control,” which helped to make symptomatic therapy<br />

more acceptable to the medical pr<strong>of</strong>ession.<br />

Not only had Dr. Reidenberg conceptualized<br />

“Individualized <strong>Medicine</strong>,” he was driving a number<br />

<strong>of</strong> other advancements in research. His studies<br />

showed that: proper controls are equally important<br />

when studying adverse drug reactions as in studying<br />

beneficial reactions; impaired renal function changes<br />

the dose-response relationships <strong>of</strong> drugs; and age is<br />

an important independent variable affecting doseresponse.<br />

The latter conclusion has since influenced<br />

the care <strong>of</strong> the elderly.<br />

“The individualization <strong>of</strong> drug therapy, now called<br />

personalized medicine, is to try to make the response<br />

more predictable. We can tailor the choice and dose<br />

<strong>of</strong> a drug depending on how well we understand<br />

an individual’s state – how best can we predict their<br />

response.”<br />

A Neglected New Frontier in Pharmacology<br />

Dr. Reidenberg’s ASPET talk focuses on the<br />

question: What can happen “after” a drug is<br />

discontinued? As an example, he will explore a study<br />

based on patients admitted to a hospital who had<br />

Acute Coronary Syndromes; some were on statins<br />

prior to admission, some not. For those who entered<br />

the hospital and were on statins, when the statins<br />

were discontinued, there was a greater incidence <strong>of</strong><br />

mortality. “We talk about withdrawal for opioids or<br />

barbiturates, but if it’s not a mood affecting drug,<br />

we tend to neglect withdrawal reactions. Today, the<br />

science has advanced enough that we have both<br />

laboratory and clinical ways to assess if there are<br />

these withdrawal responses – either biochemically<br />

in the lab or by seeing what happens to patients in<br />

the clinical trials for the week or two after the drug<br />

was stopped and the trial was over.”<br />

New Horizons in Clinical Pharamacology<br />

“When I was starting out, genes were something<br />

in peas researched in an Austrian monastery. Before<br />

the explosion <strong>of</strong> knowledge in genetics, we were<br />

looking at disease interactions – liver disease, kidney<br />

disease and different rates <strong>of</strong> drug metabolism and<br />

how to address it. We dealt with more or less,<br />

more <strong>of</strong> a drug or less <strong>of</strong> it. But today, because <strong>of</strong><br />

advancements in genetics, we’re looking at an all<br />

or nothing response. We’re seeing that a particular<br />

gene or mutation, when present, can give either<br />

an all or nothing response – either you respond to<br />

a drug, or not. We first started to understand this<br />

all or nothing response with respect to bacterial<br />

resistance. We saw certain changes in bacteria<br />

(in response to a drug) in those people who were<br />

receiving an antibiotic that selected for bacteria<br />

genetically resistant to the antibiotic. The antibiotic<br />

had to be changed in order to treat the infection<br />

that did not respond to the first drug.”<br />

“We have advanced to the point that,<br />

today, personalized medicine is working on the<br />

individualization <strong>of</strong> therapy (meaning choice <strong>of</strong><br />

drug and the best dose) using a patient’s genetics,”<br />

says Dr. Reidenberg. “It’s a great time to be<br />

a pharmacologist.”<br />

“When I was<br />

starting out, genes<br />

were something<br />

in peas researched<br />

in an Austrian<br />

monastery.”<br />

Dr. Marcus Reidenberg (L)<br />

Dr. Sandeep Kishore (R)<br />

Not only had<br />

Dr. Reidenberg<br />

conceptualized<br />

“Individualized<br />

<strong>Medicine</strong>,” he<br />

was driving a<br />

number <strong>of</strong> other<br />

advancements in<br />

research.<br />

14 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 15


GHESKIO Research Leads to Change<br />

WHO Treatment Guidelines: Earlier Is Better for HIV Treatment<br />

Early initiation <strong>of</strong> antiretroviral therapy significantly<br />

increases survival rates among HIV-1 patients.<br />

Published in The New England Journal <strong>of</strong> <strong>Medicine</strong>,<br />

researchers at GHESKIO, <strong>Weill</strong> <strong>Cornell</strong>’s research,<br />

training and clinical service operation in Haiti,<br />

produced data between 2005 and 2008 based on 816<br />

HIV-1 infected subjects. Their results led to changes<br />

in treatment guidelines published by WHO in 2010.<br />

The United States <strong>Department</strong> <strong>of</strong> Health and Human<br />

Services also updated treatment recommendations.<br />

The researchers, who include several <strong>of</strong> <strong>Weill</strong> <strong>Cornell</strong><br />

Medical College’s top infectious and tropical disease<br />

experts, also showed that early intervention is linked<br />

to a decreased rate <strong>of</strong> incident tuberculosis, a leading<br />

cause <strong>of</strong> death among HIV patients in resource-poor<br />

countries. Previous to this most recent GHESKIO study, standard treatment practice<br />

for HIV patients indicated beginning antiretroviral therapy (ART) only at a certain<br />

clinical threshold: when the measure <strong>of</strong> a patient’s CD4+ T cell count – a critical<br />

immune-system cell – dips below 200 cells per cubic millimeter. Clinical evidence<br />

has long shown that HIV patients become vulnerable to life-threatening illness<br />

long before their CD4 count hits 200, but no one had yet definitively established<br />

that antiretroviral therapy (ART) is effective before that crucial number. Because<br />

antiretroviral medications are prone – much like antibiotics – to eliciting drug<br />

resistance in the target disease, establishing that evidence was essential. GHESKIO<br />

researchers concluded that for HIV-1-infected patients, ART is best initiated as<br />

early as at a CD4 count <strong>of</strong> 350 or lower in order to improve survival and to reduce<br />

co-infection with TB, creating a new paradigm for the treatment <strong>of</strong> AIDS.<br />

L to R: Drs. Fitzgerald (senior author), Johnson,Gulick,<br />

and Severe (lead author).<br />

The paper’s authors include Senior Physician at GHESKIO<br />

Patrice Severe, MD, a graduate student in the WCMC<br />

Program in Clinical Epidemiology and Health Services<br />

Research; Associate Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> Daniel W.<br />

Fitzgerald, MD, who leads clinical research and public<br />

health initiatives in Haiti and Tanzania; Pr<strong>of</strong>essor <strong>of</strong><br />

<strong>Medicine</strong> and Chief <strong>of</strong> the Division <strong>of</strong> Infectious Diseases<br />

Roy M. Gulick, MD, an early champion <strong>of</strong> antiretroviral<br />

“cocktail” therapy for HIV; B.H. Kean Pr<strong>of</strong>essor <strong>of</strong> Tropical<br />

<strong>Medicine</strong> Warren D. Johnson, Jr., MD, who is Director <strong>of</strong><br />

the Center for Global Health; and Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Jean W. Pape, MD, Founding Director <strong>of</strong> GHESKIO.<br />

Where do Medical Research and Social Media Meet?<br />

Dr. Robert Kaner (L)<br />

Physician-scientists in the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> are implementing a complex <strong>of</strong> technological strategies<br />

tailored to educating potential recruits on clinical trials. Robert Hagerty, Subject Recruitment Manager, has<br />

joined the <strong>Department</strong> after 15 years at New York University serving as Senior Research<br />

Coordinator. He has spearheaded the development <strong>of</strong> a database-driven website where<br />

patients and healthy volunteers can find a wealth <strong>of</strong> information on all clinical trials<br />

conducted within the department.<br />

Mr. Hagerty and Robert J. Kaner, MD, Associate Pr<strong>of</strong>essor <strong>of</strong> Clinical <strong>Medicine</strong> and<br />

an investigator in idiopathic pulmonary fibrosis (IPF), have developed a recruitment<br />

strategy for Dr. Kaner’s current studies centered around social media. A blog and a<br />

Facebook page with patient-friendly information about IPF and <strong>Weill</strong> <strong>Cornell</strong>’s research<br />

and treatment services has been created. “Each <strong>of</strong> these efforts helps widen our net <strong>of</strong><br />

potential subjects, and they are all linked to each other on the web, so views <strong>of</strong> the blog<br />

increase hits to the Facebook page, which leads to more traffic on the <strong>of</strong>ficial website,<br />

and so on,” says Mr. Hagerty.<br />

Social media is relatively new in the realm <strong>of</strong> academic medicine, but it appears to<br />

be a tool well suited to the task <strong>of</strong> broadening a subject recruitment base. Traditionally, investigators have relied<br />

largely on physicians referring their own patients to studies. The Internet brings the study right to the patient’s<br />

fingertips, while allowing researchers direct access to a much wider pool <strong>of</strong> potential recruits. “This is especially<br />

helpful in a market like New York City,” says Dr. Kaner, “where there are several academic medical centers<br />

appealing to the same population base and where physician-referral patterns are fairly entrenched.”<br />

The “first” to use social media ...<br />

Dr. Kaner, whose IPF trial is part <strong>of</strong> a larger, nationwide IPF study funded by the National Institutes <strong>of</strong> Health,<br />

was the first <strong>of</strong> the study’s 21 principal investigators to utilize social media for patient recruitment. In a meeting<br />

<strong>of</strong> the study principals and NIH overseers in November 2010, Dr. Kaner presented his new strategy. “The whole<br />

roomful <strong>of</strong> investigators was very excited, and the people from the NIH were definitely paying attention.”<br />

16 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 17


The Physician-Scientist?<br />

Endangered but not Vanishing<br />

Editor <strong>of</strong> the book, The Vanishing Physician-Scientist?, Dr. Andrew Schafer is focused<br />

on a departmental goal <strong>of</strong> paramount importance – to foster the careers <strong>of</strong> young<br />

physician-scientists.<br />

Dr. Schafer (L); Dr. Karl Pillemer (C), Pr<strong>of</strong>essor <strong>of</strong> Human Development and Associate Dean<br />

for Extension and Outreach, College <strong>of</strong> Human Ecology, and Dr. Alan Mathios, Dean <strong>of</strong> the<br />

College <strong>of</strong> Human Ecology (<strong>Cornell</strong> University, Ithaca)<br />

As a medical student, Dr. Schafer discovered that<br />

it is “exhilarating to be able to take a clinical question<br />

into the laboratory to try to understand its underlying<br />

basis.” He was spurred by an inspiring clinical<br />

pr<strong>of</strong>essor to devise and perform experiments with<br />

blood samples from a patient with sickle cell anemia<br />

who had unusual infectious problems to determine<br />

if the patient had a defect in his white blood cells<br />

that interfered with their ability to absorb bacteria.<br />

“This experience helped me decide not only to<br />

become a clinical hematologist but also a scientist.”<br />

As in Dr. Schafer’s case, physicians can directly<br />

bring to the medical research laboratory the unique<br />

perspective <strong>of</strong> being able to ask questions inspired<br />

by their personal experience <strong>of</strong> caring for patients.<br />

In this way, they ideally complement the scientific<br />

perspective <strong>of</strong> PhD medical investigators. Entering<br />

the 21st century, however, the extraordinary pace<br />

<strong>of</strong> discovery in biomedical sciences and the rapid<br />

technological advances in clinical practice have<br />

created a widening knowledge gap – and even<br />

language barrier – between practicing physicians and<br />

laboratory scientists. It is important to understand<br />

other contemporary factors – demographic,<br />

sociologic and economic – that have increasingly<br />

discouraged physicians from entering research<br />

careers. As a result, the number <strong>of</strong> medical doctors<br />

seeking research grants has been in relatively steep<br />

decline.<br />

A collaboration between the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> and scientists at <strong>Cornell</strong> Ithaca is paving the way<br />

for advancements in polycythemia vera, a myeloproliferative disease that causes excess production <strong>of</strong> red<br />

blood cells, white blood cells, and platelets. The disease impairs blood flow to the brain by thickening the<br />

blood itself. Dr. Andrew Schafer and Dr. Richard Silver, Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> and a renowned authority<br />

in polycythemia vera, are collaborating with Dr. Chris Schaffer and Dr. William Olbricht (<strong>Department</strong> <strong>of</strong><br />

Biomedical Engineering) at <strong>Cornell</strong> Ithaca.<br />

The techniques being developed in the laboratory (<strong>Cornell</strong> Ithaca) involve physiologically-based<br />

numerical models <strong>of</strong> blood flow. Ultimately, the goal is to determine if reduced cerebral blood flow, due to<br />

polycythemia vera, can cause neural dysfunction; for instance, cognitive decline or dementia. Results may<br />

also open the door to new insights in the fields <strong>of</strong> stroke and cardiovascular diseases.<br />

“As medicine moves increasingly into<br />

a time when treatment modalities<br />

will be more targeted and personalized,<br />

the observations and insights doctors<br />

make while caring for patients will<br />

become increasingly invaluable,”<br />

says Dr. Schafer. “The goal is to infect<br />

young physicians with a passion<br />

to research.”<br />

Dr. Andrew Schafer visiting<br />

Dr. Christopher Schaffer in the<br />

Schaffer laboratory (<strong>Cornell</strong><br />

University, Ithaca). They are<br />

working with a femtosecond<br />

laser system used to visualize<br />

the structure and function<br />

<strong>of</strong> individual cells, and to<br />

target structures <strong>of</strong> the brain,<br />

towards uncovering cellular<br />

dynamics that underlie<br />

neurological disease.<br />

(L to R) Drs. Schafer, William Olbricht (Biomedical Engineering, <strong>Cornell</strong> University),<br />

Christopher Schaffer; (2nd from R) Thom Puifai Santisakultarm (in the Biomedical<br />

Engineering PhD program at <strong>Cornell</strong> University) has received mentorship from<br />

Dr. Andrew Schafer and Dr. Richard Silver (<strong>Weill</strong> <strong>Cornell</strong> Medical College) on the<br />

polycythemia vera research project (see page 19).<br />

Revitalizing and Strengthening the Physician-<br />

Scientist Career Pipeline<br />

The <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> is committed to<br />

creating an intellectually stimulating and highly<br />

collaborative environment, one that joins MD and<br />

PhD investigators in productive medical research<br />

teams. With the <strong>Weill</strong> <strong>Cornell</strong>’s NIH-funded Clinical<br />

and Translational Science Award (CTSA), under<br />

the directorship <strong>of</strong> Dr. Julianne Imperato-McGinley<br />

(Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> and Chief <strong>of</strong> the Division <strong>of</strong><br />

Endocrinology, Diabetes and Metabolism) serving as<br />

a programmatic core – along with the new medical<br />

research building under construction providing an<br />

extraordinary opportunity for research expansion –<br />

the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> is well positioned to<br />

revitalize the physician-scientist work force.<br />

18 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 19


New Leadership Appointments<br />

David Calfee, MD, MS<br />

Chief Hospital Epidemiologist<br />

David Calfee serves as the new Chief Hospital Epidemiologist at NewYork-Presbyterian/<strong>Weill</strong> <strong>Cornell</strong> Medical<br />

Center. He earned his medical degree from West Virginia University School <strong>of</strong> <strong>Medicine</strong> and completed an<br />

internship and residency in internal medicine and a fellowship in infectious diseases at the University <strong>of</strong> Virginia.<br />

He also received a master <strong>of</strong> science degree in health evaluation sciences from the University<br />

<strong>of</strong> Virginia. After completing fellowship training, he served on the faculty <strong>of</strong> the University<br />

<strong>of</strong> Virginia School <strong>of</strong> <strong>Medicine</strong>. In 2003, he relocated to New York City to become the Hospital<br />

Epidemiologist and Infection Control Officer for The Mount Sinai Hospital, where he was<br />

an Associate Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> in the Division <strong>of</strong> Infectious Diseases. His research interests<br />

include the epidemiology and prevention <strong>of</strong> healthcare-associated infections and antibiotic<br />

resistance. He is currently receiving research funding from the Centers for Disease Control<br />

and Prevention to study the clinical and molecular epidemiology <strong>of</strong> carbapenem-resistant<br />

Enterobacteriaceae in healthcare facilities in New York City. He is on the Editorial Advisory<br />

Board for Infection Control and Hospital Epidemiology and serves as an advisor to the<br />

USAID-sponsored Program to Improve the Quality and Safety <strong>of</strong> Healthcare in Egypt.<br />

He has a secondary appointment in the <strong>Department</strong> <strong>of</strong> Public Health at <strong>Weill</strong> <strong>Cornell</strong><br />

Medical College.<br />

Ana C. Krieger, MD<br />

Medical Director <strong>of</strong> the <strong>Weill</strong> <strong>Cornell</strong> Center for Sleep <strong>Medicine</strong><br />

Dr. Ana C. Krieger has been appointed Medical Director <strong>of</strong> the new <strong>Weill</strong> <strong>Cornell</strong> Center for Sleep <strong>Medicine</strong>,<br />

holding concurrent appointments in the <strong>Department</strong>s <strong>of</strong> <strong>Medicine</strong> and Neurology. Under her leadership, the<br />

Center has focused on a multidisciplinary approach to sleep disorders, having achieved full accreditation by<br />

the American Academy <strong>of</strong> Sleep <strong>Medicine</strong> in 2010. Dr. Krieger has been actively involved<br />

in patient care and innovative educational and research initiatives. She is the principal<br />

investigator on NIH sponsored translational research projects investigating the mechanisms<br />

<strong>of</strong> cardiovascular disease and thrombosis in sleep apnea. Dr. Krieger obtained her MD from<br />

the Universidade Federal do Rio Grande do Sul in Brazil and completed residency training<br />

at the University <strong>of</strong> Chicago and a fellowship at New York University. At New York<br />

University, she also received an MPH with a focus on healthcare management and policy.<br />

She is a Robert Wood Johnson Foundation Scholar and serves as a Healthcare Policy<br />

Advisor for the New York Academy <strong>of</strong> <strong>Medicine</strong>.<br />

Mary K. Crow, MD<br />

Chief <strong>of</strong> Division <strong>of</strong> Rheumatology<br />

Mary K. Crow, M.D. is a Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> and the new Chief <strong>of</strong> the Division <strong>of</strong><br />

Rheumatology in the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong>, as well as a Pr<strong>of</strong>essor <strong>of</strong> Immunology in the<br />

<strong>Weill</strong> <strong>Cornell</strong> Graduate School <strong>of</strong> Medical Sciences. Dr. Crow became Physician-in-Chief and<br />

Chair <strong>of</strong> the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> at the Hospital for Special Surgery (HSS) in 2010, where<br />

she holds the Joseph P. Routh Endowed Chair in <strong>Medicine</strong>, is Senior Scientist, Co-Director<br />

<strong>of</strong> the Mary Kirkland Center for Lupus Research, and the Director <strong>of</strong> the Autoimmunity and<br />

Inflammation Program in the Research Division. A leader in research concerning the induction<br />

and regulation <strong>of</strong> autoimmune diseases, she was among the first to characterize the functional<br />

properties <strong>of</strong> human dendritic cells and has studied self-reactive T cells in the prototype<br />

systemic autoimmune diseases, systemic lupus erythematosus and rheumatoid arthritis. She<br />

continues to investigate the underlying triggers <strong>of</strong> autoimmune disease and the cellular and<br />

cytokine mediators <strong>of</strong> immune system activation and inflammation in those disorders, and<br />

has led advancements in the identification <strong>of</strong> the central role <strong>of</strong> type I interferon in the pathogenesis <strong>of</strong> systemic<br />

autoimmune diseases. Dr. Crow has served on the Medical and Scientific Committee <strong>of</strong> the Arthritis Foundation,<br />

on the S.L.E. Foundation’s Medical Advisory Committee, and is Chair <strong>of</strong> the Scientific Advisory Board <strong>of</strong> the Alliance<br />

for Lupus Research. She is a past president <strong>of</strong> the American College <strong>of</strong> Rheumatology and the Henry Kunkel Society<br />

and was named an “Arthritis Hero” by the Arthritis Foundation in 2001. Dr. Crow received her M.D. at <strong>Weill</strong> <strong>Cornell</strong><br />

Medical College; Internal <strong>Medicine</strong> and Rheumatology subspecialty training at NewYork-Presbyterian; and postdoctoral<br />

research training at Rockefeller University in the laboratory <strong>of</strong> Dr. Henry Kunkel.<br />

Lia Logio, MD<br />

Vice Chair for Education and Residency Program Director<br />

Dr. Lia Logio is the Vice Chair for Education and Director <strong>of</strong> the Internal <strong>Medicine</strong> Residency<br />

Program. She is also the Herbert J. and Ann L. Siegel Distinguished Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong>.<br />

Previously, Dr. Logio served as the Program Director for the Internal <strong>Medicine</strong> Residency Program<br />

at Indiana University School <strong>of</strong> <strong>Medicine</strong>, where she was also the Assistant Dean <strong>of</strong> Faculty<br />

Affairs and Pr<strong>of</strong>essional Development. She received her MD from Johns Hopkins and completed<br />

residency training in internal medicine at Duke. Her teaching honors include: the Sol Goldman<br />

Award in Geriatrics from Johns Hopkins; nomination (twice) for the Eugene A. Stead Teaching<br />

Award as well as the Golden Apple Teaching Award at Duke; the Haskill Schiff Award for<br />

Excellence in Clinical <strong>Medicine</strong> and an Engel Society Faculty Inductee at Duke; Outstanding<br />

Teacher Award in General Internal <strong>Medicine</strong> and Geriatrics from Indiana University; Indiana<br />

University’s <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Distinguished Teacher Award; and the Society <strong>of</strong> General<br />

Internal <strong>Medicine</strong> Clinician Educator Award. She has served as an Associate Editor <strong>of</strong> Board<br />

Basics and as a Content Contributor to its Medical Knowledge Self-Assessment Program through the American<br />

College <strong>of</strong> Physicians. Dr. Logio has earned a national reputation as an innovator in curriculum in graduate medical<br />

education as well as in patient safety and inter-pr<strong>of</strong>essional education, and has been an invited speaker at the<br />

national level, including the Institute <strong>of</strong> <strong>Medicine</strong>’s Forum on Quality.<br />

20 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 21


New Leadership Appointments continued<br />

Honors<br />

and Awards<br />

Judy Tung, MD<br />

Director <strong>of</strong> <strong>Weill</strong> <strong>Cornell</strong> Internal <strong>Medicine</strong> Associates (WCIMA)<br />

Dr. Judy Tung has been appointed Director <strong>of</strong> <strong>Weill</strong> <strong>Cornell</strong> Internal <strong>Medicine</strong> Associates (WCIMA), within<br />

the general medicine division <strong>of</strong> the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong>. WCIMA’s longstanding excellence in clinical<br />

care and medical education stems from its distinctively blended faculty-resident practice model, rich patient<br />

diversity and unique balance <strong>of</strong> payors. WCIMA’s faculty are amongst the most highly rated clinical teachers<br />

in the medical college and comprise close to a third <strong>of</strong> the faculty serving in college leadership positions. An<br />

NCQA recognized Patient Centered Medical Home and Diabetes<br />

Center <strong>of</strong> Excellence, WCIMA also leads in clinical quality. Dr. Tung<br />

also serves as both an associate director <strong>of</strong> the internal medicine<br />

residency program and the director <strong>of</strong> the primary care track.<br />

A graduate <strong>of</strong> Albert Einstein Medical College, she completed her<br />

residency training at the University <strong>of</strong> California, San Francisco, and<br />

her chief residency at New York University/Bellevue Hospital. Her<br />

teaching awards at <strong>Weill</strong> <strong>Cornell</strong> include the J.J Smith Award (given<br />

by the house staff to an outstanding educator), the <strong>Weill</strong> <strong>Cornell</strong><br />

Medical College Award for Teaching Excellence (for the Primary Care<br />

Clerkship), and the Dean’s List.<br />

Stephen J. Wilson, MD, MPH<br />

Hospital Epidemiologist<br />

Stephen J. Wilson serves as a new Hospital Epidemiologist and is looking forward to working with<br />

Dr. Dave Calfee to build a robust academic hospital epidemiology program at NewYork-Presbyterian/<strong>Weill</strong><br />

<strong>Cornell</strong> Medical Center. Dr. Wilson received his medical degree from Duke University School <strong>of</strong> <strong>Medicine</strong><br />

and an MPH in epidemiology from the University <strong>of</strong> North Carolina School<br />

<strong>of</strong> Public Health, and completed clinical infectious diseases training at the<br />

University <strong>of</strong> California, San Francisco, Medical Center. He has held faculty<br />

positions at Duke University School <strong>of</strong> <strong>Medicine</strong> and Indiana University School<br />

<strong>of</strong> <strong>Medicine</strong> where he was a hospital epidemiologist for nine years. He has<br />

conducted epidemiologic research on a wide variety <strong>of</strong> infection control<br />

issues and mentored numerous medical students, residents, and fellows<br />

during his time at Indiana University.<br />

22 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 23


Research Awards<br />

<strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Investigator Award<br />

This award is presented annually to members <strong>of</strong> the <strong>Department</strong> <strong>of</strong><br />

<strong>Medicine</strong> below the rank <strong>of</strong> pr<strong>of</strong>essor who perform on outstanding<br />

levels in the areas <strong>of</strong> clinical and/or basic biomedical research.<br />

The award has been generously supported by the Michael Wolk<br />

Foundation.<br />

Winner<br />

Dr. Jonathan W. Weinsaft<br />

Topic: A Novel Segmentation Algorithm for Automated Cardiac<br />

MRI Assessment <strong>of</strong> Left Ventricular Diastolic Function<br />

Division: Cardiology<br />

Runners Up<br />

Dr. Richard R. Furman<br />

Topic: Interim Results from a Phase I Study <strong>of</strong> CAL-101, a Selective<br />

Oral Inhibitor <strong>of</strong> Phosphatidylinositol 3-Kinase P110 Is<strong>of</strong>orm, in<br />

Patients with Relapsed or Refractory Hematologic Malignancies<br />

Division: Hematology and Medical Oncology<br />

Dr. Scott T. Tagawa<br />

Topic: Radiolabeled Anti-Prostate Specific Membrane Angigen<br />

(PSMA) Monoclonal Antibody J591 for Castration-resistant Prostate<br />

Cancer (CRPC)<br />

Division: Hematology and Medical Oncology<br />

The David E. Rogers Memorial Research Award<br />

This award was established in 1995 to encourage medical<br />

residents to continue their investigative research in internal<br />

medicine. This grant was made possible through an endowment<br />

by the education division <strong>of</strong> Marion Merril Dow, Inc., in honor<br />

<strong>of</strong> Dr. David E. Rogers, a scholar dedicated to the education and<br />

training <strong>of</strong> young physicians for nearly 50 years. Senior medical<br />

residents submit research abstracts for consideration to the David<br />

E. Rogers Research Committee in the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong>.<br />

Four finalists are then chosen to present their work during Medical<br />

Grand Rounds and each receives a monetary prize. The award<br />

is bestowed on the senior medical resident who performs and<br />

presents the most outstanding research.<br />

Winner<br />

Dr. Jason S. Chinitz<br />

Topic: In Vivo Detection <strong>of</strong> Subclinical Papillary Muscle Infarction<br />

by Cardiac MRI — A Novel Structural Predictor <strong>of</strong> Post-MI Mitral<br />

Regurgitation<br />

Second Place<br />

Dr. James J. Harding<br />

Topic: Determination <strong>of</strong> Circulating Serum Cytokine Pr<strong>of</strong>iles in<br />

Patients with B Cell Chronic Lymphocytic Leukemia<br />

Fellows Research Award<br />

Initiated in 2002, this award is presented annually to fellows within<br />

the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> who have presented outstanding<br />

research.<br />

Winner<br />

Dr. Elizabeth L. Alexander<br />

Topic: A Metabolomics-based Approach to Vancomycinheteroresistant<br />

Staphylococcus aureus<br />

Division: Infectious Diseases<br />

Runners Up<br />

Dr. Himisha Beltran<br />

Topic: The Molecular Basis <strong>of</strong> Neuroendocrine Prostate Cancer<br />

Division: Hematology and Medical Oncology<br />

Dr. Jessica K. Gordon<br />

Topic: Imatinib Mesylate (Gleevec) Treatment <strong>of</strong> Patients with<br />

Diffuse Cutaneous Systemic Sclerosis: Changes in Histopathology<br />

and Gene Expression<br />

Division: Rheumatology<br />

2010 Teaching Awards<br />

Senior List<br />

This award was established by the WCMC Class <strong>of</strong> 1994 to<br />

recognize 17 faculty members who have made a commitment<br />

to and demonstrated excellence in teaching. Of those 17, the<br />

following faculty members were selected from the <strong>Department</strong> <strong>of</strong><br />

<strong>Medicine</strong>.<br />

Dr. Charles L. Bardes<br />

Dr. Morton D. Bogdon<strong>of</strong>f<br />

Dr. Heather X. Cereste<br />

Dr. Salvatore Cilmi<br />

Dr. Byron P. Demopoulos<br />

Dr. Veronica M. LoFaso<br />

Dr. Susana R. Morales<br />

Dr. Anthony Ogedegbe<br />

Dr. Judy Tung<br />

Dr. Hooman Yaghoobzadeh<br />

Dr. Dana Zappetti<br />

Volunteer Clinical Faculty Award<br />

<strong>of</strong> Alpha Omega Alpha<br />

Recommended by the graduating class and selected by student<br />

members <strong>of</strong> the AOA chapter, this award is given to a voluntary<br />

faculty member who effectively and generously donates his/her<br />

time, skill and experience to teaching clinical skills.<br />

Recipient: Dr. Timothy C. Dutta<br />

House Staff Teaching Award<br />

This award was established by the Class <strong>of</strong> 1990 and the Alumni<br />

Association to honor the <strong>Weill</strong> <strong>Cornell</strong>-affiliated house <strong>of</strong>ficer who<br />

best demonstrates clinical excellence and dedication to teaching.<br />

Recipient: Dr. Won Kim<br />

The Charles L. Bardes, MD Teaching Prize<br />

This award was established in 2000 by David and Betty Cooper<br />

Wallerstein in gratitude for the excellent and compassionate<br />

medical care provided by Dr. Bardes to three generations <strong>of</strong> the<br />

Cooper-Wallerstein family. The prize is awarded annually to a<br />

member <strong>of</strong> the faculty who, in the opinion <strong>of</strong> the prize committee,<br />

has been an outstanding teacher at the <strong>Weill</strong> <strong>Cornell</strong> Medical<br />

College, demonstrating leadership, dedication and concern for the<br />

students.<br />

Recipient: Dr. B. Robert Meyer<br />

The Leonard P. Tow Humanism Award<br />

Presented by the Gold Foundation<br />

This award was first given in 1998 to recognize medical education<br />

that is compassionate and humanistic. By vote <strong>of</strong> a committee <strong>of</strong><br />

faculty members and students, the award is presented to recognize<br />

and honor one faculty member and one graduating student at<br />

WCMC who demonstrate the highest standard <strong>of</strong> compassion and<br />

sensitivity in their interaction with patients.<br />

Faculty Recipient: Dr. Veronica M. LoFaso<br />

The Richard A. Herrmann, MD Teaching Award<br />

This award was established in 2000 by Ms. Marilyn N. Herrmann in<br />

loving memory <strong>of</strong> her late husband. A member <strong>of</strong> the <strong>Department</strong><br />

<strong>of</strong> <strong>Medicine</strong> for many years, Dr. Herrmann was considered a gifted<br />

clinical teacher. The award is given to an outstanding teacher in<br />

the third year and is chosen by members <strong>of</strong> the third-year medical<br />

school class.<br />

Recipient: Dr. Salvatore Cilmi<br />

Excellence in Teaching Award<br />

Dr. Joseph J. Fins<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Dr. Keith A. LaScalea<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Dr. Eliot J. Lazar<br />

Associate Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Dr. Anthony Ogedegbe<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Runners Up<br />

Dr. Brendan J. Carolan<br />

Topic: Quantification <strong>of</strong> Cystic Fibrosis Transmembrane<br />

Conductance Regulator Gene mRNA Transcripts in Human Small<br />

Airway Epithelium<br />

Dr. Konstantinos Charitakis<br />

Topic: Defective Perinatal Myosin Produces Nemaline Myopathy<br />

and Embryonic Lethality: A New Role for Perinatal Myosin in<br />

Mammalian Growth and Development<br />

Dr. David N. Posnett<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Dr. Arun Rao<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Clinical <strong>Medicine</strong><br />

Dr. Bruce W. Stewart<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Clinical <strong>Medicine</strong><br />

Dr. Joseph Fins<br />

24 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 25


Endowed Chairs and Pr<strong>of</strong>essorships in the<br />

<strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

Emilie Roy Corey Pr<strong>of</strong>essor in Geriatrics and<br />

Gerontology<br />

Dr. Ronald D. Adelman<br />

Ralph A. Baer Pr<strong>of</strong>essor <strong>of</strong> Medical Research<br />

Dr. Phyllis August<br />

Gladys and Roland Harriman Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Dr. Craig T. Basson (end date 9/2010)<br />

Dr. Brendan M. Reilly<br />

Virginia F. and William R. Salomon Chair in Musculoskeletal<br />

Research (HSS)<br />

Dr. Carl Blobel<br />

William T. Foley Distinguished Pr<strong>of</strong>essor in <strong>Medicine</strong><br />

Dr. Mary E. Charlson<br />

Joseph P. Routh Pr<strong>of</strong>essor <strong>of</strong> Rheumatic Diseases in <strong>Medicine</strong><br />

Dr. Mary K. Crow<br />

Dr. Stephen A. Paget (end date 3/2010)<br />

Benjamin M. Rosen Chair in Immunology and Inflammation<br />

Research (HSS)<br />

Dr. Mary K. Crow<br />

The Bruce Webster Pr<strong>of</strong>essor <strong>of</strong> Internal <strong>Medicine</strong><br />

Dr. Ronald G. Crystal<br />

Henry R. Erle, MD–Roberts Family Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Dr. Andrew J. Dannenberg<br />

Lisa and Sanford B. Ehrenkranz Pr<strong>of</strong>essor in Women’s Health<br />

Dr. Orli R. Etingin<br />

Dr. Manikkam Suthanthiran (2nd from L)<br />

in his laboratory.<br />

E. William Davis, MD Pr<strong>of</strong>essorship <strong>of</strong> Medical Ethics<br />

Dr. Joseph J. Fins<br />

St. Giles Research Chair (HSS)<br />

Dr. Steven R. Goldring<br />

Stephen and Suzanne Weiss Dean<br />

Dr. Antonio M. Gotto, Jr.<br />

Revlon Pharmaceutical Pr<strong>of</strong>essor <strong>of</strong> Pharmacology and Toxicology<br />

Dr. Lorraine J. Gudas<br />

O. Wayne Isom Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Dr. Barbara L. Hempstead<br />

Abby Rockefeller Mauzé Distinguished Pr<strong>of</strong>essorship in<br />

Endocrinology in <strong>Medicine</strong><br />

Dr. Julianne L. Imperato-McGinley<br />

David H. Koch Chair for Arthritis and Tissue Degeneration Research<br />

(HSS)<br />

Dr. Lionel B. Ivashkiv<br />

Vincent Astor Distinguished Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Dr. Ira M. Jacobson<br />

B.H. Kean Pr<strong>of</strong>essor <strong>of</strong> Tropical <strong>Medicine</strong><br />

Dr. Warren D. Johnson, Jr.<br />

Richard P. Cohen, MD Associate Pr<strong>of</strong>essor <strong>of</strong> Medical Education<br />

Dr. Yoon Kang<br />

David S. Blumenthal Assistant Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Dr. Robert J. Kim<br />

The William S. Paley Pr<strong>of</strong>essor <strong>of</strong> Clinical <strong>Medicine</strong><br />

Dr. Harvey Klein<br />

Irene F. and I. Roy Psaty Distinguished Pr<strong>of</strong>essor <strong>of</strong><br />

Clinical <strong>Medicine</strong><br />

Dr. Mark S. Lachs<br />

Richard T. Silver Distinguished Pr<strong>of</strong>essor <strong>of</strong> Hematology and<br />

Medical Oncology<br />

Dr. John P. Leonard<br />

Hilda Altschul Master Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Dr. Bruce B. Lerman<br />

Herbert J. and Ann L. Siegel Distinguished Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

(as <strong>of</strong> Jan 2011)<br />

Dr. Lia S. Logio<br />

Morton Coleman Assistant Pr<strong>of</strong>essor in Multiple Myeloma<br />

Dr. Tomer M. Mark<br />

Ehrenkranz Family/Orli R. Etingin, MD Associate Pr<strong>of</strong>essor in<br />

Women’s Health<br />

Dr. Shari R. Midoneck<br />

Arthur R. Ashe, Jr. Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Dr. Henry W. Murray<br />

Nanette Laitman Distinguished Pr<strong>of</strong>essor <strong>of</strong> Public Health<br />

Dr. Alvin I. Mushlin<br />

Lewis Thomas University Pr<strong>of</strong>essor<br />

Dr. Ralph L. Nachman<br />

Mark W. Pasmantier Pr<strong>of</strong>essor <strong>of</strong> Hematology and Oncology in<br />

<strong>Medicine</strong><br />

Dr. David M. Nanus<br />

Stephen A. Paget, MD, Chair in Rheumatology (HSS)<br />

Dr. Stephen A. Paget<br />

Louis and Gertrude Feil Pr<strong>of</strong>essor <strong>of</strong> Clinical <strong>Medicine</strong><br />

Dr. R.A. Rees Pritchett<br />

Arthur B. Belfer Pr<strong>of</strong>essor in Genetic <strong>Medicine</strong><br />

Dr. Shahin A. Rafii<br />

The Ida and Theo Rossi Distinguished Pr<strong>of</strong>essor <strong>of</strong> Clinical <strong>Medicine</strong><br />

Dr. Isadore Rosenfeld<br />

Collette Kean Research Chair (HSS)<br />

Dr. Jane E. Salmon<br />

The E. Hugh Luckey Distinguished Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Dr. Andrew I. Schafer<br />

Jill Roberts Associate Pr<strong>of</strong>essor <strong>of</strong> Inflammatory Bowel Disease<br />

Dr. Ellen J. Scherl<br />

Franchellie M. Cadwell Chair (HSS)<br />

Dr. Sergio Schwartzman<br />

Mason Adams Pr<strong>of</strong>essor <strong>of</strong> Geriatric <strong>Medicine</strong><br />

Dr. Eugenia L. Siegler<br />

Rochelle Belfer Pr<strong>of</strong>essor in <strong>Medicine</strong><br />

Dr. Kendall A. Smith<br />

Howard and Carol Holtzmann Pr<strong>of</strong>essor in Clinical <strong>Medicine</strong><br />

Dr. Charles R. Steinberg<br />

Jack Fishman Pr<strong>of</strong>essor <strong>of</strong> Cancer Prevention<br />

Dr. Kotha Subbaramaiah<br />

Stanton Griffis Distinguished Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Dr. Manikkam Suthanthiran<br />

Clinical Scholar Endowments<br />

The Clinical Scholar Endowment is designed to provide outstanding<br />

junior faculty members in the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> with<br />

financial support early in their careers. Support is provided<br />

specifically to help young physicians balance patient care with<br />

research and teaching. The awards allow junior faculty to make<br />

a commitment to academic medicine and, as a result, support<br />

promising new talent.<br />

Nanette Laitman Clinical Scholar in Public Health/Prevention–<br />

Women’s Health<br />

Dr. William B. Borden<br />

Anne and Ken Estabrook Clinical Scholar in Gastroenterology<br />

Dr. Brian P. Bosworth<br />

Nanette Laitman Clinical Scholar in Public Health/Community Health<br />

Dr. Carla Boutin-Foster<br />

Dr. Carla Boutin-Foster<br />

Charles, Lillian and Betty Neuwirth Clinical Scholar in Oncology<br />

Dr. Richard R. Furman<br />

Dr. Rebecca Elstrom (as <strong>of</strong> October 2010)<br />

James P. Smith Clinical Scholar Award<br />

Dr. Ben-Gary Harvey<br />

Bonnie Johnson Sacerdote Clinical Scholar in Women’s Health<br />

Dr. Elizabeth Leef Jacobson<br />

Bruce B. Lerman, MD Clinical Scholar<br />

Dr. Troy LaBounty<br />

The Joachim Silbermann Family Clinical Scholar<br />

Dr. Taryn Yeon S. Lee (ended January 2010)<br />

Abby Joseph Cohen Clinical Scholar<br />

Dr. Fay Yu-Huei Lin (as <strong>of</strong> January 2011)<br />

Thomas H. Meikle, Jr. Pr<strong>of</strong>essor <strong>of</strong> Medical Education<br />

Michael Wolk Heart Foundation Clinical Scholar in Cardiology<br />

Dr. Alan M. Weinstein<br />

Dr. Jonathan W. Weinsaft (until end <strong>of</strong> 2010)<br />

Dr. Christopher F. Liu (2009 – present)<br />

The Irving Sherwood Wright Pr<strong>of</strong>essor <strong>of</strong> Geriatrics<br />

Dr. Marc E. Weksler<br />

26 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 27


Joachim Silbermann Family Clinical Scholar in Geriatrics<br />

Dr. Veronica M. LoFaso<br />

Helen and Robert Appel Clinical Scholar<br />

Dr. Bassem M. Masri<br />

Anne Moore, MD Clinical Scholar in Hematology/Oncology<br />

Dr. Allyson J. Ocean (as <strong>of</strong> October 2010)<br />

Joachim Silbermann Family Clinical Scholar in Geriatric Palliative Care<br />

Dr. M. Cary Reid, Jr.<br />

William Randolph Hearst Foundation Clinical Scholar in<br />

Microbiology and Infectious Diseases<br />

Dr. Kyu Y. Rhee<br />

Mad<strong>of</strong>f Family Clinical Scholar in Hematology/Oncology<br />

Dr. Gail J. Roboz<br />

Dr. Ellen Ritchie (as <strong>of</strong> October 2010)<br />

Madeline and Stephen Anbinder Clinical Scholar in Hematology/<br />

Oncology<br />

Dr. Linda T. Vahdat<br />

Dr. Bryan J. Schneider (as <strong>of</strong> October 2010)<br />

Linda Horowitz Cancer Research Foundation Clinical Scholar in<br />

Gastroenterology<br />

Dr. Felice Schnoll-Sussman<br />

The Lila A. Wallis, MD Distinguished Visiting<br />

Pr<strong>of</strong>essor in Women’s Health<br />

May 25, 2010<br />

Carolyn D. Runowicz, MD<br />

Pr<strong>of</strong>essor <strong>of</strong> Obstetrics and Gynecology<br />

Division <strong>of</strong> Gynecologic Oncology<br />

Northeast Utilities Chair in Experimental Oncology<br />

Director, Carole and Ray Neag Comprehensive Cancer Center<br />

University <strong>of</strong> Connecticut Health Center<br />

The Holly Andersen Visiting Pr<strong>of</strong>essor<br />

in Integrative <strong>Medicine</strong><br />

September 28, 2010<br />

Bruce S. McEwen, PhD<br />

Alfred E. Mirsky Pr<strong>of</strong>essor<br />

Head, Harold and Margaret Milliken Hatch Laboratory<br />

<strong>of</strong> Neuroendocrinology<br />

The Rockefeller University<br />

Dr. Holly Andersen<br />

Visiting Pr<strong>of</strong>essors<br />

The Richard T. Silver, MD Visiting Pr<strong>of</strong>essor<br />

January 12, 2010<br />

Clara D. Bloomfield, MD<br />

Distinguished University Pr<strong>of</strong>essor<br />

William G. Pace III Pr<strong>of</strong>essor <strong>of</strong> Cancer Research<br />

Cancer Scholar and Senior Advisor<br />

The Ohio State University Comprehensive Cancer Center;<br />

James Cancer Hospital; Solove Research Institute<br />

The Rogosin Institute Lecture<br />

March 9, 2010<br />

Richard P. Lifton, MD, PhD<br />

Chairman, <strong>Department</strong> <strong>of</strong> Genetics<br />

Sterling Pr<strong>of</strong>essor <strong>of</strong> Genetics<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> (Nephrology)<br />

Yale School <strong>of</strong> <strong>Medicine</strong><br />

Investigator, Howard Hughes Medical Institute<br />

The Isadore Rosenfeld Visiting Pr<strong>of</strong>essor<br />

April 13, 2010<br />

Michael J. Landzberg, MD<br />

Director, Boston Adult Congenital Heart (BACH)<br />

and Pulmonary Hypertension Service<br />

Associate in Cardiology<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Children’s Hospital Boston<br />

Dr. Joseph Ruggiero<br />

The Stephen Scheidt, MD Distinguished Visiting Pr<strong>of</strong>essor<br />

Sponsored by the New York Cardiology Foundation<br />

October 26, 2010<br />

David A. Kass, MD<br />

Abraham and Virginia Weiss Pr<strong>of</strong>essor <strong>of</strong> Cardiology<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong>, Pr<strong>of</strong>essor <strong>of</strong> Biomedical Engineering<br />

The Johns Hopkins University School <strong>of</strong> <strong>Medicine</strong><br />

The B.H. Kean–Boxer Family Foundation Lecture<br />

in Global Health<br />

November 2, 2010<br />

Julio Frenk, MD, MPH, PhD<br />

Dean, Harvard School <strong>of</strong> Public Health<br />

The Aaron Feder Visiting Pr<strong>of</strong>essor<br />

November 9, 2010<br />

W. Michael Scheld, MD<br />

The Bayer–Gerald L. Mandell Pr<strong>of</strong>essor <strong>of</strong> Internal <strong>Medicine</strong><br />

Division <strong>of</strong> Infectious Diseases<br />

Clinical Pr<strong>of</strong>essor <strong>of</strong> Neurosurgery<br />

Director, Pfizer Initiative in International Health<br />

University <strong>of</strong> Virginia Health System<br />

The Arthur Ashe Endowment–Christopher L. Barley, MD<br />

Lecture<br />

November 16, 2010<br />

Seth Berkley, MD<br />

President and CEO<br />

International AIDS Vaccine Initiative<br />

The Ralph L. Nachman, MD Distinguished Visiting Pr<strong>of</strong>essor<br />

November 30, 2010<br />

David Ginsburg, MD<br />

James V. Neel Distinguished University Pr<strong>of</strong>essor <strong>of</strong><br />

Internal <strong>Medicine</strong> and Human Genetics<br />

Research Pr<strong>of</strong>essor, Life Sciences Institute<br />

University <strong>of</strong> Michigan Medical School<br />

Investigator, Howard Hughes Medical Institute<br />

The Daniel G. Miller, MD Endowed Lecture in Cancer<br />

Prevention<br />

December 14, 2010<br />

Douglas R. Lowy, MD<br />

Chief, Laboratory <strong>of</strong> Cellular Oncology<br />

Head, Signaling and Oncogenesis Section<br />

Center for Cancer Research<br />

National Cancer Institute<br />

National Institutes <strong>of</strong> Health<br />

28 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 29


New York Magazine (Best Doctors) & Castle Connolly<br />

Note: * In Castle Connolly; ** In both New York Magazine & Castle Connolly.<br />

Society Memberships<br />

Allergy<br />

Dr. Gillian Shepherd*<br />

Dr. Daniel Burton*<br />

Cardiac Electrophysiology<br />

Dr. Bruce B. Lerman**<br />

Dr. Steven Markowitz*<br />

Dr. Miguel Valderrabano (Texas Methodist)*<br />

Cardiovascular Disease<br />

Dr. Holly S. Andersen**<br />

Dr. James Blake*<br />

Dr. David S. Blumenthal**<br />

Dr. Adam Deutch*<br />

Dr. Richard Devereux*<br />

Dr. Richard Fuchs*<br />

Dr. Harvey Goldberg*<br />

Dr. Antonio Gotto, Jr.*<br />

Dr. David Guyer*<br />

Dr. Evelyn M. Horn**<br />

Dr. Lawrence A. Inra**<br />

Dr. Matteethra C. Jacob (Texas Methodist)*<br />

Dr. Mazen Kamen*<br />

Dr. Paul Kligfield*<br />

Dr. Karla M. Kurrelmeyer (Texas Methodist)*<br />

Dr. Eliot Lazar*<br />

Dr. John J. Mahmarian (Texas Methodist)*<br />

Dr. Bassem Masri*<br />

Dr. David Miller*<br />

Dr. Sherif F. Nagueh (Texas Methodist)*<br />

Dr. Martin Post*<br />

Dr. Craig M. Pratt (Texas Methodist)*<br />

Dr. Miguel A. Quinones (Texas Methodist)*<br />

Dr. Howard S. Rubin (Texas Methodist)*<br />

Dr. Richard Steingart (MSKCC)*<br />

Dr. Theodore Tyberg*<br />

Dr. Michael Wolk*<br />

Dr. William A. Zoghbi (Texas Methodist)*<br />

Endocrinology, Diabetes and<br />

Metabolism<br />

Dr. Richard S. Bockman (HSS)**<br />

Dr. David J. Brillon**<br />

Dr. Willa Hsueh (Texas Methodist)*<br />

Dr. Barry Klyde*<br />

Dr. Richard Mahler (Lenox)*<br />

Dr. Richard J. Robbins (Texas Methodist)*<br />

Dr. R. Michael Tuttle (MSKCC)**<br />

Dr. Kathleen L. Wyne (Texas Methodist)*<br />

Dr. Robert Kurtz (MSKCC)**<br />

Dr. Arnon Lambroza*<br />

Dr. Arnold Markowitz (MSKCC)*<br />

Dr. Franklin Marsh*<br />

Dr. Paul Miskovitz**<br />

Dr. Jerry Nagler*<br />

Dr. Mark Pochapin**<br />

Dr. Paul F. Miskovitz (MSKCC)**<br />

Dr. Ian L. Sachs (Texas Methodist)*<br />

Dr. Ellen Scherl*<br />

Dr. Moshe Shike*<br />

Geriatrics<br />

Dr. Ronald Adelman*<br />

Dr. Mark S. Lachs*<br />

Dr. Bharathi Raman*<br />

Dr. Eugenia Siegler*<br />

Dr. George E. Taffet (Texas Methodist)*<br />

Hematology<br />

Dr. Mark Brower*<br />

Dr. John Leonard*<br />

Dr. Peter Maslak (MSKCC)*<br />

Dr. John J. McCarthy (Texas Methodist)*<br />

Dr. Stephen D. Nimer (MSKCC)**<br />

Dr. David Wolf*<br />

Infectious Diseases<br />

Dr. Barry Brause (HSS)*<br />

Dr. Arthur Brown (MSKCC)*<br />

Dr. Barry J. Hartman**<br />

Dr. David Helfgott*<br />

Dr. Jonathan Jacobs*<br />

Dr. Henry Murray*<br />

Dr. Tobias C. Samo (Texas Methodist)*<br />

Dr. Kent Sepkowitz (MSKCC)*<br />

Dr. Paul Smith (HSS)*<br />

Dr. Rosemary Soave*<br />

Internal <strong>Medicine</strong><br />

Dr. Louis Aronne*<br />

Dr. Christopher Barley*<br />

Dr. Richard Cohen*<br />

Dr. Symra Cohn*<br />

Dr. Orli Etingin*<br />

Dr. Laura Fisher*<br />

Dr. Flavia Golden*<br />

Dr. Catherine Hart*<br />

Dr. Margaret Lewin*<br />

Dr. Bruce Logan*<br />

Dr. C. Ronald Mackenzie (HSS)*<br />

Dr. Samuel Mann*<br />

Dr. Deena Nelson*<br />

Dr. Mark Pecker*<br />

Dr. Ward Cunningham Rundles*<br />

Dr. David Zackson*<br />

Dr. Susan M. Escudier (Texas Methodist)*<br />

Dr. Clifford Hudis (MSKCC)*<br />

Dr. David Ilson (MSKCC)*<br />

Dr. Joseph Jurcic (MSKCC)*<br />

Dr. David Kelsen (MSKCC)*<br />

Dr. Nancy E. Kemeny (MSKCC) **<br />

Dr. Mark Kris (MSKCC)*<br />

Dr. Vincent A. Miller (MSKCC)**<br />

Dr. Anne Moore**<br />

Dr. Robert Motzer (MSKCC)*<br />

Dr. David Nanus*<br />

Dr. Larry Norton (MSKCC)**<br />

Dr. Kenneth Offit (MSKCC)*<br />

Dr. Eileen M. O’Reilly (MSKCC)**<br />

Dr. Mark W. Pasmantier**<br />

Dr. David G. Pfister (MSKCC)**<br />

Dr. Naiyer Rizvi (MSKCC)*<br />

Dr. Mark Robson (MSKCC)*<br />

Dr. Joseph T. Ruggiero**<br />

Dr. Leonard Saltz (MSKCC)*<br />

Dr. David Scheinberg (MSKCC)*<br />

Dr. Howard I. Scher (MSKCC)**<br />

Dr. Nancy Sklarin (MSKCC)*<br />

Dr. Susan Slovin (MSKCC)*<br />

Dr. David R. Spriggs (MSKCC)*<br />

Dr. David Straus (MSKCC)*<br />

Dr. Scott Tagawa*<br />

Dr. Jeffrey Tepler*<br />

Dr. Linda Vahdat*<br />

Dr. Andrew D. Zelenetz (MSKCC)**<br />

Nephrology<br />

Dr. Phyllis August**<br />

Dr. Jon D. Blumenfeld (Rogosin)**<br />

Dr. Stuart Saal (Rogosin)*<br />

Dr. Raymond Sherman*<br />

Dr. John Wang (Rogosin)*<br />

Pulmonary<br />

Dr. Joseph T. Cooke **<br />

Dr. Daniel M. Libby**<br />

Dr. Thomas W. Nash**<br />

Dr. David Posner (Lenox, Adjunct)*<br />

Dr. Abraham Sanders *<br />

Dr. Diane Stover-Pepe (MSKCC)*<br />

Institute <strong>of</strong> <strong>Medicine</strong> <strong>of</strong> the National Academy <strong>of</strong> Sciences<br />

Dr. Joseph J. Fins<br />

Dr. Antonio M. Gotto, Jr.<br />

Dr. Ralph L. Nachman<br />

Dr. Jean W. Pape<br />

Dr. David J. Skorton<br />

Association <strong>of</strong> American Physicians<br />

Dr. Jeremiah A. Barondess<br />

Dr. Morton D. Bogdon<strong>of</strong>f<br />

Dr. Mary E. Charlson<br />

Dr. Bayard D. Clarkson (MSKCC Affiliate)<br />

Dr. Ronald G. Crystal<br />

Dr. Andrew J. Dannenberg<br />

Dr. James A. Fagin (MSKCC Affiliate)<br />

Dr. Antonio M. Gotto, Jr.<br />

Dr. Katherine A. Hajjar (secondary appointment)<br />

Dr. Barbara L. Hempstead<br />

Dr. Jules Hirsch (Rockefeller Affiliate)<br />

Dr. Alan N. Houghton (MSKCC Affiliate)<br />

Dr. Julianne L. Imperato-McGinley<br />

Dr. Warren D. Johnson, Jr.<br />

Dr. Attallah Kappas (Rockefeller Emeritus)<br />

Dr. Mary Jeanne Kreek (Rockefeller Affiliate)<br />

Dr. Aaron J. Marcus<br />

Dr. Paul A. Marks (MSKCC Affiliate)<br />

Dr. Henry W. Murray<br />

Dr. Ralph L. Nachman<br />

Dr. David M. Nanus<br />

Dr. Carl F. Nathan (secondary appointment)<br />

Dr. Marcus M. Reidenberg<br />

Dr. Jane E. Salmon (HSS Affiliate)<br />

Dr. Charles L. Sawyers (MSKCC Affiliate)<br />

Dr. Andrew I. Schafer<br />

Dr. David A. Scheinberg (MSKCC Affiliate)<br />

Dr. Manikkam Suthanthiran<br />

Dr. Babette B. Weksler<br />

Dr. Marc E. Weksler<br />

Dr. Sidney J. Winawer (MSKCC Affiliate)<br />

Dr. Alastair J.J. Wood (Courtesy)<br />

The American Society for Clinical Investigation<br />

Dr. John D. Baxter (Texas Methodist Hospital Affiliate)<br />

Dr. Richard S. Bockman (HSS Affiliate)<br />

Dr. Morton D. Bogdon<strong>of</strong>f (Emeritus)<br />

Dr. Ralph Carmel (New York Methodist Hospital Affiliate)<br />

Dr. Bayard D. Clarkson (MSKCC Affiliate)<br />

Dr. Ronald G. Crystal<br />

Dr. Andrew J. Dannenberg<br />

Dr. James A. Fagin (MSKCC Affiliate)<br />

Dr. Michael S. Glickman (MSKCC Affiliate)<br />

Dr. Antonio M. Gotto, Jr.<br />

Dr. Roy M. Gulick<br />

Dr. Katherine A. Hajjar (secondary appointment)<br />

Dr. Barbara L. Hempstead<br />

Dr. Jules Hirsch (Rockefeller Affiliate)<br />

Dr. Peter R. Holt (Rockefeller Affiliate)<br />

Dr. Alan N. Houghton (MSKCC Affiliate)<br />

Dr. Lionel B. Ivashkiv (HSS Affiliate)<br />

Dr. Eric A. Jaffe (Adjunct)<br />

Dr. Lawrence J. Kagen (HSS Affiliate)<br />

Dr. Attallah Kappas (Rockefeller Emeritus)<br />

Dr. Richard N. Kolesnick (MSKCC Affiliate)<br />

Dr. Ione A. Kourides<br />

Dr. Jeffrey C. Laurence<br />

Dr. John P. Leonard<br />

Dr. Martin Lipkin<br />

Dr. Aaron J. Marcus<br />

Dr. Paul A. Marks (MSKCC Affiliate)<br />

Dr. Ari M. Melnick<br />

Dr. Henry W. Murray<br />

Dr. James M. Musser (Texas Methodist Hospital Affiliate)<br />

Dr. Ralph L. Nachman<br />

Dr. David M. Nanus<br />

Dr. Carl F. Nathan (secondary appointment)<br />

Dr. Stephen D. Nimer (MSKCC Affiliate)<br />

Dr. Kenneth Offit (MSKCC Affiliate)<br />

Dr. Eric G. Pamer (MSKCC Affiliate)<br />

Dr. David N. Posnett<br />

Dr. Shahin Rafii<br />

Dr. Marcus M. Reidenberg<br />

Dr. Arleen B. Rifkind<br />

Dr. Michel Sadelain (MSKCC Affiliate)<br />

Dr. Charles L. Sawyers (MSKCC Affiliate)<br />

Dr. Andrew I. Schafer<br />

Dr. David A. Scheinberg (MSKCC Affiliate)<br />

Dr. Kendall A. Smith<br />

Dr. Manikkam Suthanthiran<br />

Dr. Marcel van den Brink (MSKCC Affiliate)<br />

Dr. Alan M. Weinstein<br />

Dr. Babette B. Weksler<br />

Dr. Marc E. Weksler<br />

Dr. Alastair J.J. Wood (Courtesy)<br />

Rheumatology (HSS affiliates)<br />

Dr. Theodore R. Fields**<br />

Dr. Allan Gib<strong>of</strong>sky*<br />

Dr. Susan Goodman*<br />

Gastroenterology<br />

Dr. Paul Basuk*<br />

Dr. Michael Cantor*<br />

Dr. Bradley Connor*<br />

Dr. Robert Cooper*<br />

Dr. Gulchin A. Ergun (Texas Methodist)*<br />

Dr. Hans Gerdes (MSKCC)**<br />

Dr. Howard Goldin*<br />

Dr. Ira M. Jacobson**<br />

Medical Oncology<br />

Dr. Dean F. Bajorin (MSKCC)**<br />

Dr. Michael D. Lockshin**<br />

Dr. Steven Magid*<br />

Dr. Joseph Markenson*<br />

Dr. Stephen Paget*<br />

Dr. Edward Parrish*<br />

Dr. Jane Salmon*<br />

Dr. Serio Schwartzman*<br />

Dr. Sandra L. Sessoms (Texas Methodist)*<br />

Dr. Robert Spiera*<br />

Dr. George J. Bosl (MSKCC)**<br />

Dr. Richard Stern*<br />

Dr. Morton Coleman*<br />

Dr. Arthur Yee*<br />

30 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 31


Dr. Juliet B. Aizer: Member, CARE 2010 Development Group,<br />

American College <strong>of</strong> Rheumatology; Medical Knowledge Self<br />

Assessment Program Committee, Rheumatology Section, American<br />

College <strong>of</strong> Physicians<br />

Dr. Elizabeth L. Alexander: Program Committee Choice Award<br />

and Plenary Presentation, 48th Annual Meeting <strong>of</strong> the Infectious<br />

Diseases Society <strong>of</strong> America, Canada<br />

Dr. Phyllis August: Elected Member, American Clinical and<br />

Climatological Association<br />

Dr. Susan Clark Ball: Inaugural Andrew Swanson Memorial<br />

Lecturer, Hospital for Special Surgery<br />

Dr. Anne R. Bass: Chair, Training Resources Subcommittee<br />

<strong>of</strong> the Committee on Workforce and Training, American College<br />

<strong>of</strong> Rheumatology<br />

Dr. William B. Borden: Young Hearts Award for Achievement in<br />

Cardiovascular Science and <strong>Medicine</strong>, American Heart Association<br />

Young Pr<strong>of</strong>essionals<br />

Dr. Brian P. Bosworth: Invited speaker, American College <strong>of</strong><br />

Gastroenterology Fellows Forum; Chair, Small Bowel Abstract<br />

Review Committee, Education Committee, and Chair, Peer Review<br />

Subcommittee, American College <strong>of</strong> Gastroenterology<br />

Dr. Carla Boutin-Foster: Member, Public Health Council,<br />

New York State <strong>Department</strong> <strong>of</strong> Health<br />

Dr. David J. Brillon: Chair, Research Review Committee, EDIC<br />

Dr. David P. Calfee: Advisor, Program to Improve the Quality and<br />

Safety <strong>of</strong> Healthcare in Egypt, U.S. Naval Medical Research Unit and<br />

U.S. Agency for International Development, Cairo, Egypt; Invited<br />

speaker, National Academy <strong>of</strong> Infusion Therapy<br />

Dr. Mary E. Charlson: Invited speaker, NHLBI Conference “Future<br />

Research Directions to Prevent Cardiovascular Disease and its Risk<br />

Factors among Latinos”; Member, Scientific Review Committee,<br />

NIH Cardiovascular and Sleep Epidemiology Study Section;<br />

Invited speaker, NIH-sponsored Workshop “Translating Ideas into<br />

Intervention”<br />

Dr. David J. Christini: Invited speaker, Heart Rhythm Society<br />

Scientific Sessions<br />

Dr. Joseph T. Cooke: Invited speaker, Member, Medical Advisory<br />

Board, and Award <strong>of</strong> Appreciation for Efforts in Donation after<br />

Cardiac Death, New York Organ Donor Network; Center for the<br />

Performing Artist Symposium; Institute <strong>of</strong> Labor Relations, <strong>Cornell</strong><br />

University; Association <strong>of</strong> American Medical College Quality<br />

Symposium; NYC Council Subcommittee on Quality and Safety<br />

in Our City Hospitals;<br />

Dr. Carl Crawford: Rudin Foundation Award<br />

Dr. Mary K. Crow: Honorary member, Interurban Clinical Club;<br />

Paul J. Bilka Endowed Lecturer, Mayo Foundation; Invited speaker,<br />

Ninth International Congress on Systemic Lupus Erythematosus;<br />

Chair, Scientific Advisory Board, Alliance for Lupus Research; Grand<br />

Opportunities Study Section, National Institute <strong>of</strong> Arthritis and<br />

Musculoskeletal and Skin Diseases, National Institutes <strong>of</strong> Health;<br />

Member, Board <strong>of</strong> Trustees, Arthritis Foundation, New York Chapter;<br />

Scientific Advisory Board, Arthritis National Research Foundation<br />

Dr. Ronald G. Crystal: Reviewer, Simone and Cino Del<br />

Luca Prize, French Academy <strong>of</strong> Sciences; Co-Chair, Program<br />

Committee, American Society <strong>of</strong> Gene and Cell Therapy<br />

2010 – 2011 Annual Meeting<br />

Dr. Andrew J. Dannenberg: Gilda’s Club New York City<br />

Advancement <strong>of</strong> Cancer Research Award; Co-Chair, Scientific<br />

Program Committee, American Association for Cancer Research<br />

Frontiers in Cancer Prevention Research Conference; Chair, Head<br />

and Neck Cancer SPORE External Scientific Advisory Board,<br />

The Johns Hopkins University School <strong>of</strong> <strong>Medicine</strong><br />

Dr. Maria T. DeSancho: Invited presenter, Women’s Health 2010:<br />

The 18th Annual Congress <strong>of</strong> the American Medical Women’s<br />

Association<br />

Dr. Richard B. Devereux: Chair, Observational Study Monitoring<br />

Board for the Multiethnic Study <strong>of</strong> Atherosclerosis (MESA), National<br />

Heart Lung and Blood Institute; Director, Eastern Regional Chapter,<br />

American Society <strong>of</strong> Hypertension; Invited lecturer, 39th Annual<br />

Meeting <strong>of</strong> the Association <strong>of</strong> American Indian Physicians<br />

Dr. Jennifer Downs: Invited presenter, American Society <strong>of</strong> Tropical<br />

<strong>Medicine</strong> and Hygiene Meeting; Invited speaker, Female Genital<br />

Schistosomiasis Workshop, Bill and Melinda Gates Foundation,<br />

Denmark<br />

Dr. Rebecca Elstrom: Member, Lymphoma Committee, Cancer and<br />

Leukemia Group B, National Cancer Institute<br />

Dr. Doruk Erkan: Co-Chair, Abstract Review Committee,<br />

Antiphospholipid Syndrome, Annual Scientific Meeting, American<br />

College <strong>of</strong> Rheumatology; Executive Committee, New York<br />

Rheumatism Association; Member, Grant Review Committee, Annual<br />

Scientific Grant Application, Dutch Arthritis Foundation; Member,<br />

Medical and Scientific Committee, New York Chapter, Arthritis<br />

Foundation<br />

Dr. Theodore R. Fields: Member, Abstract Selection Committee:<br />

Quality Measures and Innovations in Practice Management and Care<br />

Delivery, American College <strong>of</strong> Rheumatology<br />

Dr. Maria E. Figueroa De Alcaide: Special Fellow Award, Leukemia<br />

and Lymphoma Society; Invited speaker, Hematology-in-Focus<br />

Session on Myelodysplastic Syndromes, Fifteenth Congress <strong>of</strong> the<br />

European Hematology Association, Spain<br />

Dr. Joseph J. Fins: Elected member, Institute <strong>of</strong> <strong>Medicine</strong> (IOM);<br />

Elected member, American Clinical and Climatological Association;<br />

President-Elect, American Society for Bioethics and Humanities;<br />

Council Member, Europaische Akademie Bad Neuenahr-Ahrweiler<br />

GmbH (The European Academy), Germany; John P. McGovern<br />

Award Lecture in the Medical Humanities, Institute for the Medical<br />

Humanities, University <strong>of</strong> Texas Medical Branch; Vice Chair, Fellows<br />

Council, and Member <strong>of</strong> the Board <strong>of</strong> Trustees, The Hastings Center<br />

Dr. Daniel W. Fitzgerald: Invited speaker, Haiti: A Case Study for<br />

Advancing Global Health, American Society <strong>of</strong> Tropical medicine and<br />

Hygiene Global Health Pre-Annual Meeting<br />

Dr. Richard R. Furman: Chair, CLL Education Session, 2010 ASH<br />

Meeting, American Society <strong>of</strong> Hematology; Member, CLL Steering<br />

Committee, National Cancer Institute<br />

Dr. Joy Gelbman: Member, Medical Leadership Committee,<br />

American Heart Association Go Red For Women Campaign<br />

Dr. Paraskevi Giannakakou: Ad hoc member and Invited member,<br />

Basic Mechanisms <strong>of</strong> Cancer Therapeutics Study Section, National<br />

Cancer Institute<br />

Dr. Allan Gib<strong>of</strong>sky: Chair, U.S. Committee for the International<br />

Treat-to-Target Rheumatoid Arthritis Initiative; Consultant, Arthritis<br />

Advisory Committee, U.S. Food and Drug Administration<br />

Dr. Marshall J. Glesby: Invited speaker, 17th Conference on<br />

Retroviruses and Opportunistic Infections; Royal Society <strong>of</strong> <strong>Medicine</strong><br />

Meeting, United Kingdom<br />

Dr. Steven R. Goldring: Invited speaker, European Workshop <strong>of</strong><br />

Rheumatology Research; Visiting pr<strong>of</strong>essor and speaker, University<br />

<strong>of</strong> Massachusetts Medical Center; Chair, Basic Science Program<br />

Committee, Annual Meeting, American College <strong>of</strong> Rheumatology<br />

Dr. Jessica K. Gordon: Arthritis Foundation Fellowship Award in<br />

Inflammatory Arthritis; National Scleroderma Foundation Award;<br />

Charles L. Christian Musculoskeletal Research Award<br />

Dr. Roy M. Gulick: Member, Organizing Committee, 10th<br />

International Congress on HIV and Drug Therapy in HIV Infection,<br />

Scotland, and Scientific Committee, 6th International AIDS Society<br />

Conference on HIV Pathogenesis, Treatment and Prevention, Rome;<br />

Chairman, International AIDS Society-USA Annual CME Meeting;<br />

Invited speaker, 48th Annual Meeting <strong>of</strong> the Infectious Diseases<br />

Society <strong>of</strong> America, Vancouver, and 11th Annual International<br />

Symposium on HIV/AIDS, Mexico; Plenary speaker: 10th National<br />

Conference on Infectious Diseases and Clinical Microbiology,<br />

Portugal; Speaker, Satellite Symposium on Hepatitis, HIV/AIDS and<br />

Influenza, Open Medical Institute, Almaty, Kazashstan; Visiting<br />

Pr<strong>of</strong>essor, University <strong>of</strong> Kwazulu-Natal, South Africa<br />

Dr. Monica L. Guzman: Director’s New Innovator Award, National<br />

Institutes <strong>of</strong> Health; Scientific Reviewer, Breast Cancer Research<br />

Program, 2010 Congressionally Directed Medical Research Program;<br />

Invited speaker, Translational Science Roundtable discussion on<br />

cancer stem cells, Life Sciences Summit 2010<br />

Dr. Barbara L. Hempstead: Member, Board <strong>of</strong> Scientific<br />

Counselors, National Institute <strong>of</strong> Child Health and Development,<br />

National Institutes <strong>of</strong> Health<br />

Dr. Evelyn M. Horn: Workforce Leader, Pulmonary Hypertension<br />

Council Standards and Guidelines Committee, International Society<br />

for Heart and Lung Transplantation; Co-Chair, International Society<br />

for Heart & Lung Transplantation Symposium; Visiting Pr<strong>of</strong>essor and<br />

Distinguished Panelist, American Heart Association Fellows Society<br />

<strong>of</strong> Greater New York<br />

Dr. Julianne L. Imperato-McGinley: Urban Health Conference<br />

2010; From Bench to Bedside to Community – Translating Medical<br />

Research into Action; Member, Clinical Research Forum<br />

Dr. Ira M. Jacobson: Invited speaker, American Association for the<br />

Study <strong>of</strong> Liver Diseases 2010 Postgraduate Course<br />

Dr. Steven G. Jenkins: President, New York City Branch, American<br />

Society <strong>of</strong> Microbiology; President, Medical Mycology Society<br />

<strong>of</strong> New York<br />

Dr. Warren D. Johnson, Jr: Tribute held in Salvador, Brazil, March<br />

2010, honoring 40 years <strong>of</strong> contribution to global health and<br />

research in Brazil<br />

Dr. George D. Kalliolias: The SLE Foundation Research Award<br />

Dr. Robert J. Kaner: Outstanding Clinician Award, New York<br />

State Thoracic Society; Chairman, Adjudication Committee for<br />

IPFNET, National Heart, Lung and Blood Institute, National Institutes<br />

<strong>of</strong> Health; Session Co-Chair, 2010 American Thoracic Society<br />

International Conference on Cases from the IPFNET Adjudication<br />

Committee<br />

Dr. Kyriakos A. Kirou: Member, Medical and Scientific Committee<br />

and Planning Committee, Stavros Niarchos International Fellowship<br />

Exchange Program, Arthritis Foundation<br />

Dr. Jorge R. Kizer: Invited presenter, American Heart Association<br />

Epidemiology and Prevention Scientific Sessions; Invited presenter,<br />

American Heart Association Scientific Sessions<br />

Dr. Paul D. Kligfield: President, International Society for<br />

Computerized Electrocardiology; Member, Board <strong>of</strong> Directors,<br />

Computing in Cardiology; Member, Executive Committee, Member,<br />

FDA ECG Warehouse Working Group, Cardiac Safety Research<br />

Consortium<br />

Dr. Ana C. Krieger: Invited speaker, Third International Congress on<br />

Sleep <strong>Medicine</strong>; New York State Representative, Board <strong>of</strong> Directors,<br />

and Interim President, Northeastern Sleep Society; Research<br />

Committee Officer, American Academy <strong>of</strong> Sleep <strong>Medicine</strong>; Health<br />

Policy Committee Officer, New York State Society <strong>of</strong> Sleep <strong>Medicine</strong><br />

Dr. Jeffrey C. Laurence: Invited speaker, TREAT Asia AIDS<br />

Symposium (sponsored by NIH and amFAR/Dutch government),<br />

Indonesia; Plenary speaker, International Maternal Pediatric<br />

Adolescent AIDS Clinical Trials Impact Group, National Institutes<br />

<strong>of</strong> Health; Invited speaker, Keystone Conference on AIDS<br />

Pathogenesis, NIH<br />

Dr. John P. Leonard: Chair-Elect, Scientific Advisory Board,<br />

Lymphoma Research Foundation; Invited lecturer, Meet the Pr<strong>of</strong>essor,<br />

American Society <strong>of</strong> Clinical Oncology Annual Meeting; Coordinating<br />

Abstract Reviewer, Oral Abstract Session Chair, and Invited speaker,<br />

Education Session, American Society <strong>of</strong> Hematology; Invited speaker,<br />

Aggressive Lymphoma Symposium, Italy; Invited lecturer, Wake<br />

Forest University; Invited lecturer, Tufts University<br />

Dr. Bruce B. Lerman: Invited speaker, Heart Rhythm Society; Invited<br />

speaker, International Conference <strong>of</strong> Arrhythmias, Venice; Co-Editor,<br />

Topics <strong>of</strong> Arrhythmia and Ischemic Heart Disease; Co-Editor, Topics in<br />

Structural Heart Disease<br />

Dr. Michael D. Lockshin: Ira M. Goldstein Memorial Lecture,<br />

New York University; Member, Organizing Committee, and<br />

Invited speaker, 13th International Congress on Antiphospholipid<br />

Antibodies; Editor, Arthritis and Rheumatism<br />

Dr. C. Ronald MacKenzie: Chair, Committee on Ethics and Conflict<br />

<strong>of</strong> Interest, American College <strong>of</strong> Rheumatology<br />

Dr. Lisa A. Mandl: Young Investigator Subcommittee, Committee<br />

on Research, American College <strong>of</strong> Rheumatology; Translational<br />

Research Advisory Committee, Study Section, National Institutes <strong>of</strong><br />

Health and Study Section, Arthritis Foundation<br />

Dr. Aaron J. Marcus: Counselor, New York Society for the Study<br />

<strong>of</strong> Blood; Featured speaker, One Hundredth Anniversary, Interurban<br />

Clinical Club; Invited speaker, American Society <strong>of</strong> Hematology;<br />

Invited speaker, Gordon Conference on Hemostasis and Thrombosis<br />

Dr. Peter Martin: Lymphoma Core Committee, Cancer and<br />

Leukemia Group B, National Cancer Institute; Invited speaker,<br />

West Virginia Oncology Society Annual Meeting; Invited speaker,<br />

Cancer and Leukemia Group B; Invited speaker, Lymphoma and<br />

Myeloma 2010<br />

Dr. Ari M. Melnick: Member, Executive Committee, Scientific<br />

Advisory Board, and Chair, Awards Committee, Lymphoma Research<br />

Foundation; External Advisory Board, Lymphoma SPORE,<br />

MD Anderson Cancer Center<br />

Dr. James K. Min: Abstract <strong>of</strong> the Year, Society <strong>of</strong> Cardiovascular<br />

Computed Tomography Scientific Sessions; Vice-President and<br />

President-Elect, Society <strong>of</strong> Cardiovascular Computed Tomography;<br />

Member, Medicare Coverage Advisory Committee<br />

Dr. Anne Moore: Lifetime Achievement honoree, Cancer Survivors<br />

Hall <strong>of</strong> Fame, Cancer Research and Treatment Fund<br />

Dr. David M. Nanus: 2010 Gold DOC Award, The Arnold P. Gold<br />

Foundation; Program Director, Oncology Practice Reviews 2010;<br />

Co-Program Director, Seventh Annual Current Trends in Genitourinary<br />

Malignancies; Faculty member, ASCO University Renal Cell Cancer<br />

Tumor Board, American Society for Clinical Oncology<br />

Dr. Ruben Niesvizky: Honorary Chairman, Laugh for Life, Multiple<br />

Myeloma Research Foundation; Chair and Vice Chair, Onyx 003/004<br />

Independent Response Review Committee; Member, Abstract<br />

Review Committee, American Society <strong>of</strong> Hematology; Invited<br />

presenter, 2010 American Society <strong>of</strong> Clinical Oncology Annual<br />

Meeting; Invited presenter, American Society <strong>of</strong> Hematology 2010<br />

Annual Meeting and Exposition<br />

32 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 33


Dr. Stephen A. Paget: Consultant, The Rockefeller University<br />

Hospital; Member, National Scientific Advisory Council; American<br />

Federation for Aging Research; Editorial Board, Rheumatology News;<br />

Advisory Editor and Co-Editor, Arthritis and Rheumatism; Associate<br />

Editor, Clinical and Experimental Rheumatology<br />

Dr. Jean W. Pape: Clinton Global Citizen Award, Clinton Global<br />

Initiative; <strong>Weill</strong> <strong>Cornell</strong> Medical College Alumni Association Award;<br />

Lifetime Award for work on tuberculosis, International Union<br />

Against Tuberculosis and Lung Disease, North American Chapter;<br />

Jonathan Mann Health Human Rights Award, International<br />

Association <strong>of</strong> Physicians in AIDS Care; Prix Christophe Meireux,<br />

Institute de France; Carlos Slim Health 2010 Award, Research<br />

Career, Carlos Slim Health Institute<br />

Dr. Janey C. Peterson: Invited speaker, NHLBI Conference “The<br />

Sixth Mixed Methods International Conference”; Invited speaker,<br />

NIH-sponsored Workshop “Translating Ideas into Interventions”<br />

Dr. Karl Pillemer (PhD): 2010 M. Powell Lawton Award, Polisher<br />

Research Institute <strong>of</strong> the Madlyn and Leonard Abramson Center for<br />

Jewish Life/Gerontological Society <strong>of</strong> America<br />

Dr. Mark Pochapin: Member, Board <strong>of</strong> Trustees, American College<br />

<strong>of</strong> Gastroenterology; Co-Chair, Evidence-Based Education and<br />

Outreach Task Group, National Colorectal Cancer Roundtable;<br />

Co-Chair, Education and Outreach Committee, New York Citywide<br />

Colon Cancer Control Coalition (C5); Co-Chair, Colorectal Cancer<br />

Task Group, American College <strong>of</strong> Obstetricians and Gynecologists<br />

Dr. Marcus M. Reidenberg: Torald Sollmann Award, American<br />

Society for Pharmacology and Experimental Therapeutics<br />

Dr. Kyu Y. Rhee: Grand Challenges Explorations Grant and Grand<br />

Challenges TB Drug Accelerator Program Grant, Bill and Melinda<br />

Gates Foundation; Invited speaker, Novartis Institute for Tropical<br />

Diseases Symposium on Tuberculosis, Yaounde, Cameroon; U.S.-<br />

Japan Cooperative Medical Sciences Program, 45th Tuberculosis and<br />

Leprosy Research Conference, Broad Institute; World TB Day, Public<br />

Health Research Institute<br />

Dr. Richard B. Roberts: Honorary Membership, Polish Society<br />

<strong>of</strong> Epidemiology and Infectious Diseases; Austrian Cross <strong>of</strong> Honor<br />

for Science and Art, First Class<br />

Dr. Gail J. Roboz: Invited member, Leukemia Core Committee,<br />

Cancer and Leukemia Group B, National Cancer Institute;<br />

Coordinating Reviewer for abstracts on acute myeloid leukemia<br />

(AML) and AML session chair, American Society <strong>of</strong> Hematology;<br />

Invited speaker, Super-Friday Symposium, Invited member, Consult<br />

a Colleague Program, and Invited speaker, Highlights <strong>of</strong> ASH Series,<br />

American Society <strong>of</strong> Hematology<br />

Dr. Mary J. Roman: Invited speaker, North American Artery<br />

Inaugural Symposium; Invited speaker, American Society <strong>of</strong><br />

Hypertension Annual Meeting; Member, Editorial Board, Arthritis<br />

& Rheumatism; Member, Executive Committee, Board <strong>of</strong> Directors,<br />

National Marfan Foundation<br />

Dr. Howard E. Rosenberg: Medical Director <strong>of</strong> Health Services,<br />

The Juilliard School<br />

Dr. Joseph T. Ruggiero: Member, Cancer Education Committee,<br />

and Associate Editor, ASCO Self-Evaluation Program, American<br />

Society <strong>of</strong> Clinical Oncology<br />

Dr. Jane E. Salmon: Pfizer Visiting Pr<strong>of</strong>essor in Rheumatology,<br />

University <strong>of</strong> Kentucky; Invited speaker, Opening Plenary<br />

Session, 2010 European League Against Rheumatism Meeting;<br />

Laura J. Haddad Lectureship, Georgetown University Hospital;<br />

Invited speaker, Ninth International Congress on Systemic Lupus<br />

Erythematosus; Secretary-Treasurer and Member, Centers <strong>of</strong><br />

Excellence Committee, Federation <strong>of</strong> Clinical Immunology Societies;<br />

Member, Scientific Programme Committee, European League<br />

Against Rheumatism; Scientific Councilor, The Henry Kunkel Society<br />

Dr. Andrew I. Schafer: Elected President, Association <strong>of</strong> Pr<strong>of</strong>essors<br />

<strong>of</strong> <strong>Medicine</strong>; Elected Master, American College <strong>of</strong> Physicians;<br />

Councilor, American Clinical and Climatological Association;<br />

Physician-Pro-Tempore, Northwestern University<br />

Dr. Felice Schnoll-Sussman: Co-Chair, Quality in Endoscopy<br />

Initiative, New York City <strong>Department</strong> <strong>of</strong> Health and Citywide<br />

Colon Cancer Control Coalition (C5); President, New York Society<br />

for Gastrointestinal Endoscopy; Co-Director, American College <strong>of</strong><br />

Gastroenterology Regional Postgraduate Course<br />

Dr. Richard T. Silver: Invited lecturer, Investigators Board<br />

Meeting, Bristol-Myers Squibb, Czech Republic; Invited lecturer,<br />

Nineteenth International European LeukemiaNet CML Workshop,<br />

German National CML Study Group, Germany; Invited lecturer,<br />

European School <strong>of</strong> Hematology International Conference on<br />

Myeloproliferative Disorders, Portugal; Fifth Annual Houston<br />

Conference on Myelodysplastic Syndromes and Myeloproliferative<br />

Neoplasms<br />

Dr. Robert F. Spiera: President, New York Rheumatism Association;<br />

International Network for the Study <strong>of</strong> Systemic Vasculitis<br />

Dr. Manikkam Suthanthiran: Elected Member, American Clinical<br />

and Climatological Association; Councilor, The Transplantation<br />

Council; Editor, Transplantation; Plenary orator, 23rd International<br />

Congress <strong>of</strong> the Transplantation Society; Andrew Lazarovitz Lecturer,<br />

Canadian Society <strong>of</strong> Transplantation; Inaugural lecturer, University <strong>of</strong><br />

Toronto Transplant Institute<br />

Dr. Scott T. Tagawa: Co-Chair, Genitourinary Working Group,<br />

New York Cancer Consortium<br />

Dr. Ann Tilley: Clinical Research Award in COPD and AAT<br />

Deficiency, Alpha-1 Foundation and The CHEST Foundation<br />

Dr. Judy Tung: Recognition for Diabetes Excellence, National<br />

Committee for Quality Assurance<br />

Dr. Mary A. Vogler: Invited expert, Updated guidelines on<br />

antiretroviral therapy for prevention <strong>of</strong> maternal-to-child<br />

transmission <strong>of</strong> HIV and cholera, GHESKIO and the Haitian Ministry<br />

<strong>of</strong> Health<br />

Dr. Thomas J. Walsh: 2010 san<strong>of</strong>i-aventis ICAAC Award and<br />

Lecture, American Society for Microbiology; Gilbert B. Forbes<br />

Visiting Scholar, Strong Children’s Research Center, University <strong>of</strong><br />

Rochester Medical Center; First Miller Children’s Hospital Visiting<br />

Pr<strong>of</strong>essor <strong>of</strong> Pediatric Infectious Diseases; Teaching Award, Divisions<br />

<strong>of</strong> Medical Microbiology and Infectious Diseases, The Johns Hopkins<br />

University School <strong>of</strong> <strong>Medicine</strong>; Chairman, Medical Mycology, and<br />

Member, Planning Committee, 2011 Annual Meeting, American<br />

Society for Microbiology; Moderator and invited speaker, Focus on<br />

Fungal Infections 20; Invited speaker, 12th International Symposium<br />

on Febrile Neutropenia; 110th Annual Meeting <strong>of</strong> the American<br />

Society for Microbiology<br />

Dr. Jonathan W. Weinsaft: Invited reviewer, National Institute<br />

for Health Research Trainees Coordinating Center, UK; Invited<br />

lecturer, American College <strong>of</strong> Cardiology Scientific Sessions; Invited<br />

presenter, American College <strong>of</strong> Cardiology<br />

Dr. Arthur M. Yee: Member, Advisory Board, Lupus Asian Network;<br />

Medical and Scientific Committee, New York Chapter, Arthritis<br />

Foundation; Contributing Editor, The Medical Letter<br />

Dr. Dana Zappetti: Invited speaker, Multiple Small Feedings <strong>of</strong> the<br />

Mind, American College <strong>of</strong> Physicians International Conference<br />

Dr. Yuan-Shan Zhu: Editorial Board Member, The Open Andrology<br />

Journal and The Open Prostate Cancer Journal<br />

Division Pr<strong>of</strong>iles<br />

34 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 35


Division <strong>of</strong> Cardiology<br />

The Maurice R. and Corrine P. Greenberg Division<br />

<strong>of</strong> Cardiology is a leader in cardiovascular research,<br />

education and clinical care. The Division’s mission is<br />

to be at the forefront <strong>of</strong> scientific and technological<br />

developments that are revolutionizing cardiology<br />

and to translate these findings to the clinical<br />

bedside. As part <strong>of</strong> our commitment to advancing<br />

the discipline, we have assembled internationally<br />

renowned programs that investigate the basic<br />

mechanisms <strong>of</strong> cardiovascular disease, including<br />

the genetics <strong>of</strong> heart disease, the cellular signals<br />

and transcription factors responsible for cardiac<br />

development, the transformation and homing <strong>of</strong> stem<br />

cells for myocardial regeneration and the delineation<br />

<strong>of</strong> the molecular bases for cardiac arrhythmias.<br />

Clinically, our priorities are to develop and deliver<br />

cutting-edge therapies for heart disease and<br />

to advance clinical investigation. Expert faculty<br />

provide mentoring, training and supervision<br />

that prepare medical students, internal medicine<br />

residents and fellows in cardiology to be tomorrow’s<br />

leaders. The faculty also provide a host <strong>of</strong> weekly<br />

conferences for internal and external colleagues.<br />

Three clinical fellowship programs are <strong>of</strong>fered and<br />

the division partners with Brooklyn Hospital Center<br />

for an additional fellowship. Strategies are being<br />

implemented to enhance physical space, expand<br />

comprehensive clinical programs and continue our<br />

history <strong>of</strong> cutting-edge research.<br />

The Division’s mission is to be at the forefront <strong>of</strong><br />

scientific and technological developments that are<br />

revolutionizing cardiology and to translate these<br />

findings to the clinical bedside.<br />

Dr. Bruce Lerman (L)<br />

Nurse Barbara Aerni, NYP (R)<br />

Clinically, our priorities are to develop and deliver<br />

cutting-edge therapies for heart disease and to<br />

advance clinical investigation.<br />

36 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 37


Division <strong>of</strong> Cardiology continued<br />

Division <strong>of</strong> Clinical Epidemiology and<br />

Evaluative Sciences Research<br />

Bruce B. Lerman, MD<br />

Chief, Maurice R. and<br />

Corinne P. Greenberg Division<br />

<strong>of</strong> Cardiology<br />

Hilda Altschul Master<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Attending Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

Patient care<br />

covers all types<br />

<strong>of</strong> heart and<br />

vascular diseases,<br />

including, but<br />

not limited to,<br />

arrhythmias,<br />

coronary and<br />

peripheral arterial<br />

disease, valve<br />

disease, the<br />

Marfan syndrome<br />

and inherited<br />

heart diseases.<br />

From basic science investigating the mechanisms<br />

<strong>of</strong> arrhythmias and large population-based studies<br />

<strong>of</strong> new diagnostic and therapeutic approaches, to a<br />

vast array <strong>of</strong> cardiovascular conditions and diseases,<br />

the focus is on improving patient care. This involves<br />

a majority <strong>of</strong> faculty and almost all <strong>of</strong> cardiology<br />

fellows-in-training, as well as postdoctoral trainees<br />

and graduate and medical students, creating a rich<br />

intellectual milieu in which trainees can develop into<br />

experienced investigators. Clinical services achieve<br />

superior outcomes in all areas, ranging from cuttingedge<br />

interventional and imaging laboratories to<br />

outpatient consultative and ongoing care. Patient<br />

care covers all types <strong>of</strong> heart and vascular diseases,<br />

including, but not limited to, arrhythmias, coronary<br />

and peripheral arterial disease, valve disease, the<br />

Marfan syndrome and inherited heart diseases. To<br />

allow immediate treatment <strong>of</strong> patients presenting<br />

in the early stages <strong>of</strong> a heart attack, there exists<br />

24-hour, in-hospital coverage <strong>of</strong> the Cardiac Intensive<br />

Care Unit, Telemetry and Step-Down Unit and the<br />

interventional laboratory.<br />

Dr. William Borden was selected to develop,<br />

lead and direct the Atkins Curriculum in Metabolic<br />

Diseases as a new component <strong>of</strong> the medical school<br />

curriculum. Dr. Robert Kim was named the new<br />

Director <strong>of</strong> Consultative Cardiology. Many <strong>of</strong> our<br />

faculty maintained high-pr<strong>of</strong>ile leadership positions<br />

in local, national and international organizations<br />

such as the American College <strong>of</strong> Cardiology, the<br />

American Heart Association, the European Heart<br />

Rhythm Association, the Society for Cardiovascular<br />

Angiography and Intervention and the New York<br />

Cardiological Society.<br />

It was a stellar year in research funding, for both<br />

new and ongoing grants. The Division received<br />

funding from a wide array <strong>of</strong> sources covering the<br />

full spectrum <strong>of</strong> cardiovascular research.<br />

Dr. Jonathan Weinsaft was awarded a five-year K23<br />

Career Development Award from NHLBI to elucidate<br />

novel structural mechanisms and predictive indices<br />

<strong>of</strong> post-myocardial infarction mitral regurgitation,<br />

with a focus on papillary muscle infarction detected<br />

by DE-MRI tissue characterization as a longitudinal<br />

predictor <strong>of</strong> mitral regurgitation.<br />

Dr. Jorge Kizer was awarded a grant from<br />

the NHLBI to study adipocyte- and hepatocytederived<br />

biomarkers, as well as advanced glycation<br />

endproducts and fibrotic pathways, in the<br />

pathogenesis <strong>of</strong> diabetes and its cardiovascular<br />

complications.<br />

Dr. James Min received a grant from the Qatar<br />

National Research Foundation to evaluate the<br />

prevalence <strong>of</strong> coronary artery plaque characteristics<br />

in a population-based study, and to determine the<br />

relationship <strong>of</strong> those characteristics to age, gender,<br />

ethnicity, race and cardiovascular risk factors.<br />

Dr. David Christini was awarded a four-year R01<br />

grant from NHLBI to develop a framework that will<br />

enable the evaluation <strong>of</strong> potential pharmacological<br />

and device-based atrial fibrillation therapies. He was<br />

also awarded a supplement to his NHLBI grant to<br />

extend RTXI, a s<strong>of</strong>tware resource for drug screening<br />

applications developed under his leadership.<br />

Dr. William Borden was awarded a New York<br />

Community Impact grant from the American Heart<br />

Association/American Stroke Association to educate<br />

middle school students about risk factors for heart<br />

disease and engage them as leaders in improving<br />

both their own cardiovascular health and that <strong>of</strong><br />

their family members.<br />

Dr. Fay Lin was awarded a career development<br />

grant form the American Heart Association to<br />

determine the association among Heart Failure with<br />

Normal Ejection Fraction (HFNEF) patients <strong>of</strong> CAD<br />

extent and severity with LV filling pressure, and to<br />

determine the association <strong>of</strong> CAD extent and severity<br />

with HFNEF morbidity.<br />

Dr. Evelyn Horn continued to expand the<br />

Ventricular Assist Device Program, and accreditation<br />

for destination therapy from the Joint Commission<br />

on Accreditation <strong>of</strong> Healthcare Organizations granted<br />

in early 2010.<br />

Drs. Richard Devereux, Mary Roman and Jonathan<br />

Weinsaft have continued to play critical leadership<br />

roles in the NHLBI-sponsored Genetically Associated<br />

Thoracic Aortic Aneurysm (GenTAC) Registry, a new<br />

six-year phase <strong>of</strong> which was awarded in 2010. This<br />

multicenter registry has enrolled over 2,200 patients<br />

with genetically associated thoracic aortic aneurysms,<br />

with <strong>Weill</strong> <strong>Cornell</strong> contributing the largest number<br />

<strong>of</strong> participants. New findings include delineation <strong>of</strong><br />

a role <strong>of</strong> aortic annular dilatation in causing aortic<br />

regurgitation, clarification <strong>of</strong> systematic differences<br />

among methods <strong>of</strong> measuring aortic size, and<br />

estimation <strong>of</strong> rates <strong>of</strong> dissection/surgery in the distal<br />

aorta after aortic root replacement.<br />

Dr. James Min is the Principal Investigator <strong>of</strong> the<br />

Coronary CT Angiography Evaluation for Clinical<br />

Outcomes: An International Multicenter (CONFIRM)<br />

Registry, a 12-site, six-country, 27,125-patient<br />

consecutive cohort <strong>of</strong> patients undergoing coronary<br />

CT angiography and followed for downstream<br />

clinical outcomes.<br />

The new Division <strong>of</strong> Clinical Epidemiology and<br />

Evaluative Sciences Research draws upon the talents<br />

and experience <strong>of</strong> a multidisciplinary group <strong>of</strong> faculty<br />

based at <strong>Weill</strong> <strong>Cornell</strong> Medical College, <strong>Cornell</strong><br />

University, Ithaca and other institutions. Faculty<br />

members are expert in qualitative and quantitative<br />

research methodology, health services research,<br />

clinical epidemiology, medical informatics, decision<br />

sciences, health disparities research, communitybased<br />

participatory research, clinimetrics, outcomes<br />

research, behavioral science and health education.<br />

They work together in a series <strong>of</strong> activities designed<br />

to encourage and systematically support the<br />

development <strong>of</strong> new research initiatives within, as<br />

well as outside, the division. Several related are<br />

as <strong>of</strong> investigation encompass: studies to improve<br />

clinical outcomes; behavioral science research;<br />

health disparities research (under the leadership<br />

<strong>of</strong> Dr. Carla Boutin-Foster); research on complex<br />

patients with a significant burden <strong>of</strong> comorbidity;<br />

and comparative effectiveness. In order to stimulate<br />

and support new clinical, health services and<br />

outcomes research, the division houses consultative<br />

services to investigators, including informatics and<br />

data management support, as well as the currently<br />

existing training programs in clinical epidemiology<br />

and research methodology.<br />

The division has continued to expand in the area<br />

<strong>of</strong> health disparities and community-based research<br />

under the auspices <strong>of</strong> two large NIH grants: the<br />

Comprehensive Center for Excellence in Disparities<br />

Research and Community Engagement (CEDREC)<br />

grant and the Small Changes and Lasting Effects<br />

(SCALE) grant. The establishment <strong>of</strong> CEDREC<br />

resulted in the expansion <strong>of</strong> partnerships between<br />

<strong>Weill</strong> <strong>Cornell</strong>, Lincoln Hospital and Mental Health<br />

Center, Hunter College School <strong>of</strong> Nursing-City<br />

University <strong>of</strong> New York, and The Center for Healthful<br />

Behavior Change at NYU School <strong>of</strong> <strong>Medicine</strong>. As<br />

a result <strong>of</strong> SCALE, the division has a new community<br />

partner, the Northern Manhattan Perinatal Partnership<br />

(NMPP), an organization that focuses on improving<br />

health conditions such as diabetes and obesity<br />

in families who reside in Northern Manhattan. In<br />

addition to NMPP, several faith-based organizations<br />

in Harlem and the South Bronx have become<br />

critical partners in initiatives to develop health<br />

disparities research.<br />

Mary E. Charlson, MD<br />

Chief, Division <strong>of</strong> Clinical<br />

Epidemiology and Evaluative<br />

Sciences Research<br />

Executive Director, Center<br />

for Complementary and<br />

Integrative <strong>Medicine</strong><br />

William T. Foley Distinguished<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Attending Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

Faculty members are expert in qualitative and quantitative research<br />

methodology, health services research, clinical epidemiology, medical<br />

informatics, decision sciences, health disparities research, communitybased<br />

participatory research, clinimetrics, outcomes research,<br />

behavioral science and health education.<br />

38 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> (L to R) Drs. Mihir Patel, Stephen Williams, Regina Jacob (fellows); Drs. James Hollenberg, Janey Peterson, Carol Mancuso (faculty) Annual Report 2011 39


Division <strong>of</strong> Clinical Epidemiology and Evaluative Sciences Research continued<br />

Division <strong>of</strong> Clinical Pharmacology<br />

Ginger Winston, MD, who also sees patients at<br />

<strong>Weill</strong> <strong>Cornell</strong> Internal <strong>Medicine</strong> Associates (WCIMA),<br />

was appointed Assistant Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

after receiving a National Institutes <strong>of</strong> Health<br />

Minority Investigator Research Supplement to<br />

Dr. Mary Charlson’s multimillion dollar SCALE grant.<br />

Dr. Winston served her internal medicine residency<br />

and a Chief Residency at NYU Medical Center and<br />

completed a general medicine fellowship at Columbia<br />

University. She plans to become an independent<br />

clinician-investigator in cardiovascular healthcare<br />

disparities research with a focus on obesity reduction<br />

in minority communities. The NHLBI-funded SCALE<br />

research project involves small changes in eating and<br />

physical activity behavior. Body image discrepancy<br />

and risk knowledge about obesity are key constructs<br />

that will enhance our understanding and prediction<br />

<strong>of</strong> who will fare well with a small-change approach<br />

to weight loss.<br />

Home to its administrative, research, education<br />

and informatics infrastructure, the division moved<br />

to a new 8,000 square foot facility at 338 East 66th<br />

Street. The new space reunites division faculty and<br />

staff previously located at multiple sites and provides<br />

space for the additional faculty and staff recruited<br />

as a result <strong>of</strong> the CEDREC and SCALE grants.<br />

There is a conference room with teleconferencing<br />

capabilities and many other features that provide<br />

excellent resources for the division.<br />

The division has continued to expand in the area <strong>of</strong> health<br />

disparities and community-based research.<br />

Marcus M. Reidenberg, MD<br />

Chief, Division <strong>of</strong> Clinical<br />

Pharmacology<br />

Pr<strong>of</strong>essor <strong>of</strong> Pharmacology<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> Public Health<br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

The Division <strong>of</strong> Clinical Pharmacology remains actively involved in the World Health<br />

Organization (WHO) Essential <strong>Medicine</strong>s program. This important global effort evaluates, updates<br />

and publishes a list <strong>of</strong> about 300 medicines that address the world’s major medical problems.<br />

The program is designed to advise countries about which drugs should be considered priority<br />

purchases when health care resources are limited. Since 1975, the concept <strong>of</strong> prioritizing the<br />

purchase <strong>of</strong> essential medicines has been accepted in principle by 156 WHO member states.<br />

Dr. Reidenberg mentored and supervised a group <strong>of</strong> <strong>Weill</strong> <strong>Cornell</strong> students who prepared<br />

three applications for adding drugs to the Model List <strong>of</strong> Essential <strong>Medicine</strong>s and one application<br />

to change the status <strong>of</strong> a class <strong>of</strong> drugs. These were discussed at the Committee meeting at<br />

WHO headquarters in Geneva, Switzerland, in March 2011.<br />

Dr. Reidenberg is an inventor <strong>of</strong> a drug with a near-complete phase 2 clinical trial for treating<br />

hormone-refractory prostate cancer and ongoing trials in several other cancers. He continues<br />

to advise the present sponsor on further development <strong>of</strong> this drug. He also is the principal<br />

investigator <strong>of</strong> a study to discover a new drug to reduce fatal arrhythmias in patients with<br />

heart attacks.<br />

The prestigious Torald Sollmann Award (American Society <strong>of</strong> Pharmacology and Experimental<br />

Therapeutics) was given to Dr. Reidenberg based upon his outstanding and productive research<br />

career, significant contributions to medicine utilizing education, research and public service,<br />

as well as his unparalleled service to ASPET and the discipline it represents.<br />

40 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

(L) Dr. Regina Jacob (fellow) (R) Dr. Janey Peterson Annual Report 2011 41


Division <strong>of</strong> Emergency <strong>Medicine</strong><br />

We see over 76,000 patients annually, with<br />

more than 18,000 subsequently admitted to<br />

inpatient services.<br />

The Division <strong>of</strong> Emergency <strong>Medicine</strong> provides<br />

state-<strong>of</strong>-the-art emergency care to all patients,<br />

while teaching residents from all specialties how to<br />

provide that care. We are a designated 911 Receiving<br />

Hospital, a Level I Trauma Center, a Psychiatric<br />

Emergency Receiving (9.39) Center, a Burn Center<br />

for the City <strong>of</strong> New York, a Chest Pain Center<br />

accredited by the Society <strong>of</strong> Chest Pain Centers<br />

and a designated Stroke Center. Our disaster<br />

preparedness includes extensive Hazmat, and we<br />

provide biological and chemical decontamination<br />

and treatment facilities. We see over 76,000 patients<br />

annually, with more than 18,000 subsequently<br />

admitted to inpatient services. We also receive,<br />

evaluate, and stabilize patients who are transferred<br />

to us from all over the world. The <strong>Weill</strong> <strong>Cornell</strong><br />

Adult emergency department ended the year with<br />

a patient satisfaction score <strong>of</strong> 82.4, 2.8 points<br />

ahead <strong>of</strong> 2009. In February 2010, an all-time high<br />

mean score <strong>of</strong> 84.8 – the 90th percentile for “best<br />

hospital” emergency departments – was reached.<br />

The division’s Medical Toxicology Service began<br />

<strong>of</strong>fering bedside and telephone consultations<br />

throughout the hospital for all acutely or potentially<br />

poisoned patients, and to those patients experiencing<br />

the effects <strong>of</strong> chronic overdoses, withdrawal<br />

syndromes, medication errors, adverse drug reactions<br />

and other toxicologic concerns. Since its inception<br />

in 2009, the “toxicology” service has consulted on<br />

over 300 patients. The group consists <strong>of</strong> four faculty<br />

members: Dr. Flomenbaum, Drs. Jane Prosser,<br />

Brenna Farmer, and Dr. Rama Rao (director <strong>of</strong> the<br />

toxicology service). Drs. Prosser and Farmer are<br />

currently conducting local and national research<br />

in acetaminophen overdoses. Dr. Prosser holds<br />

a grant for funded research on cocaine-induced chest<br />

pain. All members <strong>of</strong> this service contribute to peer<br />

review publications and textbook chapters. Lectures<br />

in medical toxicology are <strong>of</strong>fered to all services.<br />

The service is currently developing a proposal for<br />

a rotation in medical toxicology for housestaff from<br />

several academic departments and disciplines.<br />

Our program in Geriatric Emergency <strong>Medicine</strong><br />

(GEM), the first such fellowship in the country, is<br />

supported by a new state-<strong>of</strong>-the-art emergency<br />

department facility. Major collaborative research<br />

efforts have been initiated with colleagues at the<br />

University <strong>of</strong> Toronto and the one year clinical GEM<br />

fellowship has expanded to include a second year<br />

option culminating in a Master’s degree in Clinical<br />

Investigation from <strong>Weill</strong> <strong>Cornell</strong> Graduate School <strong>of</strong><br />

Medical Sciences. GEM members have co-authored<br />

and presented abstracts at the annual American<br />

Geriatric Society national meetings and Michael<br />

Stern, Co-Director <strong>of</strong> the fellowship, co-authored<br />

a publication on orthogeriatrics. In addition to our<br />

existing didactic curriculum for EM residents, our<br />

educational content has been augmented with a<br />

monthly GEM journal club and GEM topic morning<br />

report. Dr. Halpern (and GEM group) have created<br />

a Palliative Care protocol for the ED. Development/<br />

implementation is underway for three other clinical<br />

protocols: falls prevention, urinary tract infection<br />

prevention, management <strong>of</strong> agitation/delirium.<br />

Continuing our partnership with <strong>Cornell</strong> Outdoor<br />

Education (COE) on the Ithaca campus, our unique<br />

Wilderness <strong>Medicine</strong> Program is advancing in medical<br />

education, clinical research, and clinical care, with<br />

new courses and experiences for resident and<br />

attending physicians, <strong>Cornell</strong> undergraduates and<br />

<strong>Weill</strong> <strong>Cornell</strong> medical students. Student electives<br />

continue to draw participants from all over North<br />

America and Europe and we established a residency<br />

track for those seeking an elective rotation in<br />

wilderness medicine. We also <strong>of</strong>fer an annual<br />

CME in Wilderness <strong>Medicine</strong> in Alaska and other<br />

locations for our faculty. We are collaborating with<br />

the <strong>Department</strong> <strong>of</strong> Botany (Ithaca) in translational<br />

research on botanicals throughout the world that<br />

may be useful medically. For the future: a training<br />

program for humanitarian first responders.<br />

Our department launched a Global Emergency<br />

<strong>Medicine</strong> Program. In 2010, over 23 doctors, nurses<br />

and PAs from our department served at the Disaster<br />

Recovery Center in Haiti. Overseas teaching activities<br />

expanded to Qatar and Lebanon, while ongoing<br />

research and resident electives in Guatemala and India<br />

continued. Global EM faculty organized Mumbai’s<br />

second city-wide disaster drill in collaboration with<br />

UN agencies, and federal and city institutions.<br />

The <strong>Weill</strong> <strong>Cornell</strong> Adult emergency department ended the<br />

year with a patient satisfaction score <strong>of</strong> 82.4, 2.8 points<br />

ahead <strong>of</strong> 2009.<br />

Educational activities in the medical school<br />

continue. In addition to elective courses, we serve<br />

on the medical school’s Global Health Curriculum<br />

Working Committee. Our capstone academic<br />

activity is the inaugural session <strong>of</strong> the Global<br />

Health Emergencies Course, a rigorous two-week<br />

CME-approved initiative to train doctors, nurses<br />

and mid-level providers engaged in international<br />

work. The Emergency <strong>Department</strong> implemented an<br />

electronic medical record (EMR) that it developed<br />

based on the hospital-wide Eclipsys EMR. Although<br />

components <strong>of</strong> Eclipsys had been previously utilized<br />

in the <strong>Weill</strong> <strong>Cornell</strong> ED for several years, now all<br />

nursing, physician and mid-level provider (NP, PA)<br />

documentation is done in Eclipsys, streamlining<br />

communications with all hospital staff and specialty<br />

services.<br />

Neal E. Flomenbaum, MD<br />

Chief, Division <strong>of</strong> Emergency<br />

<strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> Clinical <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Medical Director<br />

Emergency Medical Services<br />

Emergency Physician-in-Chief<br />

NewYork-Presbyterian Hospital<br />

42 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

Annual Report 2011 43


Division <strong>of</strong> Endocrinology, Diabetes<br />

and Metabolism<br />

Julianne L. Imperato-<br />

McGinley, MD<br />

Chief, Division <strong>of</strong><br />

Endocrinology, Diabetes,<br />

and Metabolism<br />

Associate Dean for<br />

Translational Research and<br />

Educational <strong>Medicine</strong><br />

Director, Clinical and<br />

Translational Science Center<br />

(CTSC)<br />

The Abby Rockefeller Mauzé<br />

Distinguished Pr<strong>of</strong>essor <strong>of</strong><br />

Endocrinology in <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical<br />

College<br />

Attending Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

As part <strong>of</strong> a world-class academic medical<br />

center, the Division <strong>of</strong> Endocrinology, Diabetes and<br />

Metabolism is committed to excellence in providing<br />

the best quality <strong>of</strong> care to patients with endocrine<br />

and metabolic disorders; in conducting promising<br />

research to advance the frontiers <strong>of</strong> endocrinology<br />

and diabetes treatment; and in training highly<br />

dedicated physicians to become successful clinicians<br />

and physician-scientists.<br />

Faculty members are dedicated to fulfilling<br />

our mission <strong>of</strong> excellence in education. The<br />

subspecialty fellowship program in endocrinology,<br />

diabetes and metabolism is designed to provide<br />

the training and experience necessary to acquire<br />

all competencies required <strong>of</strong> an expert in this field.<br />

The two-year fellowship is a joint program <strong>of</strong><br />

NewYork-Presbyterian (<strong>Weill</strong> <strong>Cornell</strong>) and Memorial<br />

Sloan-Kettering Cancer Center. Our faculty also<br />

trains internal medicine residents and leads the<br />

endocrinology section <strong>of</strong> the Basis <strong>of</strong> Disease course<br />

for medical students.<br />

Faculty conduct promising state-<strong>of</strong>-the-art<br />

research to generate new knowledge with the<br />

ultimate goal <strong>of</strong> applying the latest scientific and<br />

medical advances for the prevention, detection<br />

and treatment <strong>of</strong> patients with endocrine diseases.<br />

A hospital-wide glycemic order set was launched.<br />

The purpose <strong>of</strong> this order set is to improve overall<br />

inpatient diabetes management and decrease the<br />

rate <strong>of</strong> hyper- and hypoglycemia. Insulin is the<br />

number one cause <strong>of</strong> medical errors in the hospital<br />

setting. This order set required the collaboration<br />

<strong>of</strong> many departments including Pharmacy, Nursing,<br />

Nutrition, Laboratory, Information Technology<br />

and <strong>Medicine</strong>.<br />

Aaron Schulman, MD, who completed his<br />

fellowship at <strong>Weill</strong> <strong>Cornell</strong> in 2010 and was<br />

awarded a Certificate in Clinical Investigation,<br />

joined the Division <strong>of</strong> Endocrinology as Assistant<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong>. Dr. Schulman is significantly<br />

involved in the development, planning and execution<br />

<strong>of</strong> a research project studying the relationship<br />

<strong>of</strong> sex steroids to cardiovascular disease risk.<br />

Faculty conduct promising state-<strong>of</strong>-the-art research to generate<br />

new knowledge with the ultimate goal <strong>of</strong> applying the latest<br />

scientific and medical advances.<br />

44 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Dr. Aaron Schulman (R) with a fellow in training.<br />

Annual Report 2011 45


Division <strong>of</strong> Gastroenterology<br />

and Hepatology<br />

Dr. Jacobson visiting Dr. Rice’s lab at The Rockefeller University. (L to R) Drs. Charles Rice, Ype deJong, Ira Jacobson, Andrew Talal<br />

Ira M. Jacobson, MD<br />

Chief, Division <strong>of</strong><br />

Gastroenterology and<br />

Hepatology<br />

Vincent Astor Distinguished<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Attending Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

The Division <strong>of</strong> Gastroenterology and Hepatology<br />

provides outstanding and compassionate patient<br />

care, its faculty being active in research and education,<br />

as well as clinical care. First-rate clinical services<br />

are <strong>of</strong>fered in a wide range <strong>of</strong> subspecialty areas,<br />

including hepatology, inflammatory bowel disease,<br />

gastrointestinal reflux disease, endoscopic ultrasound<br />

and ERCP, functional bowel disorders, gastrointestinal<br />

infections and gastrointestinal cancer prevention<br />

and treatment. Numerous research studies and clinical<br />

trials are underway to study prevention and treatment<br />

<strong>of</strong> viral hepatitis, gastrointestinal cancers, Barrett’s<br />

esophagus, inflammatory bowel disease, pancreatic<br />

lesions, and other gastrointestinal diseases and<br />

ailments. Centers housed within the division include<br />

the Jay Monahan Center for Gastrointestinal Health,<br />

the Center for the Study <strong>of</strong> Hepatitis C, and The<br />

Jill Roberts Center for Inflammatory Bowel Disease.<br />

Dr. Ira M. Jacobson, Division Chief, presented<br />

pivotal phase 3 ADVANCE trial results at the 61st<br />

Annual Meeting <strong>of</strong> the American Association for the<br />

Study <strong>of</strong> Liver Diseases (AASLD) in Boston: 75 percent<br />

<strong>of</strong> treatment-naïve HCV genotype 1-infected patients<br />

treated with a telaprevir-based combination regimen<br />

for 12 weeks, followed by 12 or 36 weeks <strong>of</strong> the<br />

standard therapy <strong>of</strong> pegylated-interferon alfa-2a and<br />

ribavirin alone, achieved a viral cure; this compared<br />

to 44 percent <strong>of</strong> people treated with 48 weeks <strong>of</strong><br />

pegylated-interferon and ribavirin alone. Additionally,<br />

62 percent <strong>of</strong> patients with advanced liver fibrosis<br />

(cirrhosis or scarring <strong>of</strong> the liver) achieved a viral<br />

cure with the telaprevir regimen, compared to<br />

33 percent who were treated with pegylated-interferon<br />

and ribavirin alone. These groundbreaking data<br />

highlight telaprevir as a potential new therapy that,<br />

if approved by the FDA, could dramatically improve<br />

the future treatment <strong>of</strong> hepatitis C. The results<br />

confirm and amplified upon the findings <strong>of</strong> the U.S.<br />

phase 2 PROVE1 study, which was co-authored by<br />

Dr. Jacobson, and the European PROVE2 study; both<br />

studies were published in The New England Journal<br />

<strong>of</strong> <strong>Medicine</strong> (2009). The PROVE3 study, evaluating<br />

telaprevir in nonresponders to previous therapy,<br />

was published with Dr. Jacobson and his colleagues<br />

in 2010. He also coauthored the SPRINT-1 study<br />

<strong>of</strong> boceprevir in treatment naïve HCV genotype<br />

1 patients, published in The Lancet in 2010.<br />

At the 2010 AASLD, Dr. Jacobson was coauthor<br />

<strong>of</strong> a plenary paper on the phase 3 trial results<br />

(SPRINT-2) <strong>of</strong> another HCV protease inhibitor,<br />

boceprevir, added to peginterferon and ribavirin,<br />

demonstrating (as with telaprevir) a highly significant<br />

increase in sustained virologic response compared<br />

with standard-<strong>of</strong>-care therapy with peginterferon<br />

and ribavirin alone. A critical finding in both<br />

studies was that half a year <strong>of</strong> therapy appears to<br />

be sufficient in patients receiving either protease<br />

inhibitor (when the virus becomes undetectable<br />

after four weeks <strong>of</strong> triple therapy).<br />

These studies are critical elements <strong>of</strong> an emerging<br />

body <strong>of</strong> data signifying a new era in the treatment<br />

<strong>of</strong> chronic hepatitis C. It is fitting that <strong>Weill</strong> <strong>Cornell</strong><br />

has played a leading role in these trials, as the<br />

institution has participated in most <strong>of</strong> the key trials<br />

that have moved the field <strong>of</strong> HCV therapy forward<br />

since the initial trials with interferon monotherapy<br />

in the late 1980s. The division’s clinical trials unit<br />

remains active in a number <strong>of</strong> ongoing development<br />

programs involving a variety <strong>of</strong> classes <strong>of</strong> antiviral<br />

agents, including other protease inhibitors,<br />

polymerase inhibitors, host-targeting agents and<br />

immunotherapies.<br />

The Jay Monahan Center for Gastrointestinal<br />

Health was featured on The CBS Early Show, which<br />

aired a live broadcast <strong>of</strong> anchor Harry Smith’s<br />

colonoscopy performed by Dr. Mark Pochapin,<br />

Director <strong>of</strong> the Jay Monahan Center. CBS Evening<br />

News anchor, Katie Couric,, was on hand to support<br />

Harry Smith through the procedure, which coincided<br />

with National Colorectal Cancer Awareness Month.<br />

The Monahan Center partnered with the New York<br />

City <strong>Department</strong> <strong>of</strong> Health, Colon Cancer Challenge<br />

Foundation, Prevent Cancer Foundation, American<br />

College <strong>of</strong> Obstetricians and Gynecologists and<br />

others in numerous efforts to advance awareness<br />

and prevention <strong>of</strong> colorectal cancer. Moderated<br />

by Monahan Center social worker, Lauren Shaffer,<br />

LCSW, the center <strong>of</strong>fers an ongoing support group<br />

every 6 to 8 weeks for colorectal cancer survivors,<br />

this in addition to regular health seminars in GI<br />

health (open to patients, families, the public) and<br />

a weekly CME Case Conference in GI Cancer<br />

Prevention, Treatment and Support.<br />

At the Jill Roberts Center for Inflammatory Bowel<br />

Disease, Director Dr. Ellen Scherl has implemented<br />

five new programs: The Scherl/Roberts IBD<br />

Biobank; a monthly support group for patients<br />

and families; the New York-Moscow IBD Journal<br />

Club, conducted via Skype and accredited by the<br />

ACG; research with Dr. Richard Silver on the role<br />

<strong>of</strong> certain immune cells and pathways on IBD as<br />

seen in myeloproliferative disorders; and research<br />

with Dr. Judy Cho <strong>of</strong> Yale School <strong>of</strong> <strong>Medicine</strong> on<br />

the genetics <strong>of</strong> IBD. Collaborations continue with<br />

institutes across the globe in efforts to establish<br />

international biobanks; explore the relationship<br />

between vitamin D and IBD health; and explore IBD<br />

genotypes. Under the leadership <strong>of</strong> Dr. Scherl, the<br />

Jill Roberts IBD Center continues to collaborate with<br />

Dr. Andrew Dannenberg, Director <strong>of</strong> the WCMC-<br />

NYP Cancer Center, Dr. Kenneth Simpson at <strong>Cornell</strong><br />

University, Ithaca exploring the Microbiome in IBD,<br />

and researchers at <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

investigating NOD 2 genotyping, hemangiogenesis<br />

and animal models <strong>of</strong> colon cancer and IBD.<br />

There have been a number <strong>of</strong> developments<br />

in education. Dr. Scherl directs weekly IBD case<br />

discussions and Journal Clubs at both <strong>Weill</strong> <strong>Cornell</strong><br />

and the Columbia Campus (GI division); a monthly<br />

case correlation conference with GI pediatrics, GI<br />

pathologists, surgeons and radiologists at NYP/<br />

WCMC; and the Ellen Scherl/Jill Roberts International<br />

Scholar Program which invites an international IBD<br />

scholar to speak at the winter course each year.<br />

Dr. Brian P. Bosworth, the Anne and Ken<br />

Estabrook Clinical Scholar in Gastroenterology, was<br />

named Program Director <strong>of</strong> the Gastroenterology<br />

and Hepatology Fellowship. He was also named<br />

a Key Clinical Faculty member to the <strong>Department</strong><br />

<strong>of</strong> <strong>Medicine</strong> Residency Training Program, currently<br />

sits on the Residency Evaluation and Curriculum<br />

committees, and has served as the Chair <strong>of</strong> the Small<br />

Bowel Abstract Review Committee/American College<br />

<strong>of</strong> Gastroenterology Education Committee, leading the<br />

selection <strong>of</strong> posters and oral presentations at the ACG<br />

Annual Meeting. His other charge on the ACG was as<br />

Chair <strong>of</strong> the Peer Review Sub-committee to ensure lack<br />

<strong>of</strong> bias in presentations at ACG events.<br />

Dr. Bosworth’s clinical research resulted in five<br />

presentations each at Digestive Disease Week (including<br />

an oral presentation in the Surgical Society for the<br />

Alimentary Tract) and the ACG annual meeting.<br />

Through this work, he mentored both gastroenterology<br />

fellows and residents on a path towards a clinical<br />

research career. He also led a “Meet the Pr<strong>of</strong>essor”<br />

luncheon on “Dysplasia in Inflammatory Bowel Disease –<br />

What’s an Endoscopist to Do?”<br />

The division welcomed University <strong>of</strong> Amsterdam<br />

Medical School alumnus Ype De Jong, MD, PhD,<br />

to its faculty as an Assistant Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong>.<br />

Dr. de Jong has conducted research into the<br />

immunopathogenesis <strong>of</strong> Crohn’s disease at the<br />

Beth Israel Deaconess Medical Center in Boston.<br />

He completed his internal medicine internship, residency<br />

training, and a fellowship in gastroenterology at The<br />

Mount Sinai Medical Center. Dr. de Jong plays a key<br />

role at the Center for the Study <strong>of</strong> Hepatitis C, both<br />

as a physician at New York-Presbyterian Hospital<br />

and as a Visiting Clinical Fellow at The Rockefeller<br />

University. Trained in general gastroenterology, including<br />

endoscopy and colon cancer screening, his patient<br />

practice interests include viral hepatitis, primary biliary<br />

cirrhosis, non-alcoholic fatty liver disease and liver<br />

disease associated with inflammatory bowel disease.<br />

His research interests are geared to illuminating how<br />

hepatitis viruses can evade the immune system and are<br />

able to chronically persist in a subset <strong>of</strong> those infected.<br />

To this end, he is working on developing new models<br />

for hepatitis C virus infection in the laboratories <strong>of</strong> the<br />

Center for the Study <strong>of</strong> Hepatitis C.<br />

Dr. Mark Pochapin chaired the Evidence-Based<br />

Education and Outreach Task Group <strong>of</strong> the National<br />

Colorectal Cancer Roundtable, which developed<br />

an Evaluation Toolkit to assist community-based<br />

organizations to evaluate and report outcomes <strong>of</strong><br />

their efforts to increase colorectal cancer awareness<br />

and screening.<br />

Numerous<br />

research studies<br />

and clinical trials<br />

are underway to<br />

study prevention<br />

and treatment<br />

<strong>of</strong> viral hepatitis,<br />

gastrointestinal<br />

cancers, Barrett’s<br />

esophagus,<br />

inflammatory<br />

bowel disease,<br />

pancreatic<br />

lesions,<br />

and other<br />

gastrointestinal<br />

diseases and<br />

ailments.<br />

Dr. Brian Bosworth (2nd from R)<br />

with fellows in training.<br />

Groundbreaking<br />

data highlight<br />

telaprevir as a<br />

potential new<br />

therapy that,<br />

if approved by<br />

the FDA, could<br />

dramatically<br />

improve the<br />

future treatment<br />

<strong>of</strong> hepatitis C.<br />

46 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 47


Division <strong>of</strong> Geriatrics and Gerontology<br />

(L) Al Greenberg, <strong>of</strong> the Upper West Side, returns home after hospitalization to enjoy going to the opera<br />

48 once <strong>Department</strong> again. (R) Dr. <strong>of</strong> Eugenia <strong>Medicine</strong> Siegler, recipient <strong>of</strong> the Mason Adams Pr<strong>of</strong>essorship <strong>of</strong> Geriatric <strong>Medicine</strong>.<br />

The Center sees an increasing number <strong>of</strong> geriatric<br />

outpatients annually (average age over 80 and many<br />

vibrant centenarians).<br />

The Division <strong>of</strong> Geriatrics and Gerontology<br />

improves the quality <strong>of</strong> life for older people through<br />

the integration <strong>of</strong> high-quality clinical care, teaching<br />

geriatric medicine, and advancing knowledge<br />

through scientific research. Federal and foundation<br />

grants continue and several new research awards<br />

were received. 2010 showed a steady increase in<br />

patient volumes, both inpatient and outpatient<br />

services. U.S. News & World Report ranked NewYork-<br />

Presbyterian Hospital (NYP) seventh in the nation in<br />

geriatric medicine.<br />

The Irving Sherwood Wright Center on Aging,<br />

our ambulatory practice site, received the NYP<br />

Patient Centered Care Award for the highest-rated<br />

<strong>Department</strong> in Ambulatory Care. The Center sees an<br />

increasing number <strong>of</strong> geriatric outpatients annually<br />

(average age over 80 and many vibrant centenarians).<br />

Within the Ambulatory Care Network, the Center<br />

excels as one <strong>of</strong> the highest-ranking practices<br />

in patient satisfaction. Established by Dr. Sharda<br />

Ramsaroop, the division’s Hospital Discharge<br />

Follow-up Program has vastly improved patient<br />

care (200 patients seen since 2009). This program<br />

recognizes that the transition from hospital to<br />

home is a vulnerable time for patients.<br />

With generous support from the Gruss-Lipper<br />

Family Foundation, there has been significant<br />

progress in expanding our multidisciplinary and<br />

community-based House Call Program led by<br />

Dr. Veronica LoFaso, providing comprehensive services<br />

to the most frail, homebound elderly patients. The<br />

program maintains a collaborative relationship with<br />

DOROT, a highly regarded social services agency.<br />

Activities on the Palliative Care Consultation Service<br />

have expanded under new leadership: Division<br />

Co-Chief, Dr. Ronald Adelman, is Acting Director;<br />

Dr. Sonal Mehta, Assistant Director.<br />

Our NYC Elder Abuse Center is advancing in<br />

the field <strong>of</strong> elder justice. There are multidisciplinary<br />

team activities in Manhattan and Brooklyn, including<br />

partnerships with Maimonides Medical Center’s<br />

Division <strong>of</strong> Geriatrics and the Brooklyn VA. Funding<br />

for this new center includes: Fan Fox and Leslie<br />

R. Samuels Foundation, FJC, A Foundation <strong>of</strong><br />

Philanthropic Funds, Laura B. Vogler Foundation,<br />

and Vladimir and Araxia Buckhantz Foundation.<br />

ThisCaringHome.org, a new interactive multimedia<br />

website <strong>of</strong>fers tips for caregivers on adapting<br />

residences to the special needs <strong>of</strong> Alzheimer’s<br />

patients. Virtual tours <strong>of</strong> each type <strong>of</strong> room address<br />

the varying safety and quality-<strong>of</strong>-life issues that can<br />

arise as dementia progresses. Rosemary Bakker,<br />

Research Associate in Gerontologic Design in<br />

<strong>Medicine</strong>, published the AARP Guide to Revitalizing<br />

Your Home. Division Co-Chief, Dr. Lachs, published<br />

Treat Me, Not My Age, a book for “baby boomers”<br />

and beyond on navigating the healthcare system.<br />

The division received two five-year Geriatric<br />

Academic Career Awards (Drs. Ramsaroop and Sonal<br />

Mehta). Two new endowed pr<strong>of</strong>essorships began –<br />

the Emilie Roy Corey Pr<strong>of</strong>essorship in Geriatrics and<br />

Gerontology and the Mason Adams Pr<strong>of</strong>essorship <strong>of</strong><br />

Geriatric <strong>Medicine</strong> – held by Dr. Ronald Adelman and<br />

Dr. Eugenia Siegler, respectively. Educational initiatives<br />

and physician services in palliative care continue;<br />

funding sources include the Altman Foundation, the<br />

Ronald D. Adelman, MD<br />

Co-Chief, Division <strong>of</strong><br />

Geriatrics and Gerontology<br />

Medical Director, Irving<br />

Sherwood Wright Center<br />

on Aging<br />

The Emilie Roy Corey<br />

Pr<strong>of</strong>essor in Geriatrics and<br />

Gerontology<br />

Pr<strong>of</strong>essor <strong>of</strong> Clinical <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Attending Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

Mark S. Lachs, MD, MPH<br />

Co-Chief, Division <strong>of</strong> Geriatrics<br />

and Gerontology Director,<br />

Geriatrics for the NewYork-<br />

Presbyterian Health System<br />

The Irene F. and I. Roy Psaty<br />

Distinguished Pr<strong>of</strong>essor <strong>of</strong><br />

Clinical <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Attending Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

New York Community Trust, the Y.C. Ho/Helen and<br />

Michael Chiang Foundation and the Pincus Family<br />

Fund. Our Consortium for Psychosocial Education<br />

in Geriatrics, held a conference <strong>of</strong> 18 metropolitanarea<br />

geriatric fellowship training programs. The<br />

successful medicine clerkship Fast Forward Rounds<br />

teaches third-year medical students key aspects <strong>of</strong><br />

the discharge planning process for older adults with<br />

chronic illness.<br />

As one <strong>of</strong> 12 such centers nationally, we are in<br />

year two <strong>of</strong> the National Institute on Aging’s award<br />

(Edward R. Roybal Center for Research on Applied<br />

Gerontology), a grant that has created the <strong>Cornell</strong>-<br />

Columbia Translational Research Institute on Pain in<br />

Later Life (TRIPLL). TRIPLL is expected to reach more<br />

than 300,000 New York metro-area seniors. The new<br />

institute is an expansion <strong>of</strong> the <strong>Cornell</strong> Institute for<br />

Translational Research on Aging (CITRA) in Ithaca, NY,<br />

a Roybal Center since 2003. The Division <strong>of</strong> Geriatrics<br />

and Gerontology serves as the program’s hub,<br />

with other principal members comprising <strong>Cornell</strong><br />

University College <strong>of</strong> Human Ecology in Ithaca, and,<br />

for the first time, Columbia University Mailman<br />

School <strong>of</strong> Public Health, a leader in healthy aging<br />

and palliative care research. Other newly added<br />

members include Memorial Sloan-Kettering Cancer<br />

Center, the Hospital for Special Surgery and the<br />

Visiting Nurse Service <strong>of</strong> New York.<br />

A new interactive<br />

multimedia<br />

website <strong>of</strong>fers<br />

tips for caregivers<br />

on adapting<br />

residences to the<br />

special needs<br />

<strong>of</strong> Alzheimer’s<br />

patients.<br />

Visit ThisCaringHome.org for<br />

helpful tips on safety for the<br />

elderly.<br />

Annual Report 2011 49


Division <strong>of</strong> Hematology and<br />

Medical Oncology<br />

The Division <strong>of</strong> Hematology and Medical Oncology<br />

currently consists <strong>of</strong> three full-time clinicians (including<br />

one hospitalist), 24 clinical researchers with clinical<br />

responsibilities, five physician-scientists and 11 full-time<br />

scientists with no clinical responsibilities; voluntary<br />

faculty also participate, several with significant<br />

mentorship and philanthropic roles. Clinical services<br />

are divided into five clinical programs: Solid Tumor<br />

Oncology, Leukemia, Lymphoma/Myeloma, Stem Cell<br />

Transplant and Nonmalignant Hematology, at three<br />

sites <strong>of</strong> operation--NewYork-Presbyterian Hospital<br />

Main Campus (third floor), Oxford Building and the Iris<br />

Cantor Women’s Health Center, with expansion under<br />

way at a fourth site in the <strong>Weill</strong> Greenberg Ambulatory<br />

Care Building. In addition, clinical services are divided<br />

into disease-site specific programs. In the Solid<br />

Tumor Service, the programs are: Breast Oncology,<br />

Gastrointestinal Oncology, Genitourinary Oncology and<br />

Thoracic Oncology. The Lymphoma/Myeloma Service<br />

is subdivided into several free-standing disease-specific<br />

programs, including the CLL Research Center and the<br />

Waldenstrom’s Macroglobulinemia Program. Emerging<br />

smaller programs include Head and Neck Oncology,<br />

Neuro-Oncology and Endocrine Oncology. Each <strong>of</strong> the<br />

services works closely with faculty in the corresponding<br />

surgical oncology department, division or program.<br />

The Division houses the largest group <strong>of</strong><br />

clinical investigators in the college, and basic and<br />

translational research has benefitted from newly<br />

Remarkable strides have been accomplished<br />

in the division’s basic, translational and clinical<br />

research missions.<br />

Barbara L. Hempstead,<br />

MD, PhD<br />

Co-Chief, Division <strong>of</strong><br />

Hematology and Medical<br />

Oncology<br />

O. Wayne Isom Pr<strong>of</strong>essor<br />

<strong>of</strong> <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Attending Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

David M. Nanus, MD<br />

Co-Chief, Division <strong>of</strong><br />

Hematology and Medical<br />

Oncology<br />

Medical Director<br />

Genitourinary Oncology<br />

Program<br />

Mark W. Pasmantier Pr<strong>of</strong>essor<br />

<strong>of</strong> Hematology and Oncology<br />

in <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> Urology<br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Attending Physician<br />

NewYork-Presbyterian Hospital<br />

Dr. 50 Schafer <strong>Department</strong> (L) with <strong>of</strong> Dr. <strong>Medicine</strong> David Nanus. Annual Report 2011 51


Division <strong>of</strong> Hematology and Medical Oncology continued<br />

The Division<br />

houses the largest<br />

group <strong>of</strong> clinical<br />

investigators<br />

in the college,<br />

and basic and<br />

translational<br />

research has<br />

benefitted from<br />

newly renovated<br />

research space<br />

and multiple new<br />

recruits over the<br />

last four years.<br />

Dr. Barbara Hempstead (L)<br />

in her laboratory.<br />

52 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

renovated research space and multiple new recruits<br />

over the last four years, markedly expanding the<br />

research portfolio. Plans include expanding clinical<br />

and basic science areas <strong>of</strong> expertise, with a major<br />

emphasis on translational (bench-to-bedside) studies.<br />

As such, the division is poised to play a central<br />

role in the Cancer Center Initiative, in selective<br />

recruitment <strong>of</strong> translational scientists to the new<br />

research building, and in partnering with other<br />

divisions/departments to further expand the research<br />

base through large collaborative grants.<br />

Participation in conferences included Oncology<br />

Practice Reviews, a unique multitumor CME<br />

conference for medical oncologists and hematologists<br />

presented by Physicians’ Education Resource in<br />

conjunction with <strong>Weill</strong> <strong>Cornell</strong> Medical College.<br />

Dr. David Nanus was the program director, with<br />

wide participation from the division’s faculty. This<br />

meeting provided updates on state-<strong>of</strong>-the-art<br />

clinical management <strong>of</strong> a wide variety <strong>of</strong> solid<br />

and hematologic malignancies. It also highlighted<br />

cutting-edge information and emerging treatment<br />

strategies for breast cancer, genitourinary<br />

malignancies, gastrointestinal malignancies,<br />

lung cancer, lymphoma, multiple myeloma,<br />

myelodysplastic syndromes, leukemia and chronic<br />

lymphocytic leukemia. The Congress <strong>of</strong> Lymphoma<br />

and Myeloma 2010: An International Congress<br />

on Hematologic Malignancies was chaired by<br />

Dr. Morton Coleman.Dr. John P. Leonard co-chaired<br />

the Lymphoma Session, Dr. Ruben Niesvizky<br />

co-chaired the Myeloma Session and Dr. Richard R.<br />

Furman co-chaired the Leukemia Session. This premier<br />

forum was attended by some 1,000 participants<br />

from around the world, representing the largest CME<br />

activity to target hematologic malignancies apart<br />

from the American Society <strong>of</strong> Hematology meeting.<br />

Dr. Ari Melnick has had a tremendously productive<br />

year. His group published 14 papers in the academic<br />

year 2010, including in the Proceedings <strong>of</strong> the<br />

National Academy <strong>of</strong> Sciences, Blood, Nature<br />

<strong>Medicine</strong>, Cancer Cell, Journal <strong>of</strong> Experimental<br />

<strong>Medicine</strong>, and Cancer Research – four <strong>of</strong> these cited<br />

in the Faculty <strong>of</strong> 1000. Dr. Melnick was the lead<br />

investigator <strong>of</strong> three high pr<strong>of</strong>ile studies that<br />

(a) identified new therapeutic agents for lymphomas<br />

(Cancer Cell and Nature <strong>Medicine</strong>) and (b) in<br />

a second line <strong>of</strong> investigation revealed the first<br />

epigenetic based classification and full epigenetic<br />

characterization <strong>of</strong> a human disease, in this case<br />

leukemia (Cancer Cell). These discoveries led to a new<br />

patent <strong>of</strong> a method to predict clinical outcomes in<br />

leukemia patients using an epigenetic biomarker.<br />

Dr. Melnick continues to lead the Epigenomics Core<br />

at <strong>Weill</strong> <strong>Cornell</strong> and has recruited computer scientists<br />

and a bioinformatics specialist to assist in designing<br />

new algorithms for epigenomics research.<br />

Basic and translational investigators are established<br />

in the totally renovated basic and translational research<br />

space in the Belfer Institute <strong>of</strong> Hematology and<br />

Oncology. Many <strong>of</strong> the aspects <strong>of</strong> its design, including<br />

three rooms for videoconferences, have greatly facilitated<br />

the interactions <strong>of</strong> the Belfer faculty with clinicians in<br />

our division and with faculty at <strong>Cornell</strong> University in<br />

Ithaca, as well as other institutions. This has enabled<br />

the Belfer faculty to play leadership roles in uniting new<br />

interdisciplinary groups to enhance the translational<br />

mission <strong>of</strong> the Belfer Institute. Clinical researchers in<br />

the Belfer Institute have focused on building their<br />

academic clinical studies and establishing a tissue bank<br />

for hematologic malignancies. The division focused<br />

on two major research areas: the molecular alterations<br />

that characterize malignant cells as related to cancer<br />

development; novel therapeutic targeting and<br />

response/resistance to current therapies; and promoting<br />

translational research by fostering new collaborations<br />

with investigators outside the Belfer faculty.<br />

The divisional clinical research program enrolled<br />

more than 400 research subjects in 104 different<br />

treatment studies in 2010. Of these, 27 are<br />

investigator-initiated clinical trials, developed and<br />

overseen by one <strong>of</strong> the division’s physicians. These<br />

studies include high-impact protocols across the entire<br />

spectrum <strong>of</strong> hematologic malignancies and solid<br />

tumors, as well as projects in areas <strong>of</strong> non-malignant<br />

hematology. The CLL (chronic lymphocyte leukemia)<br />

Research Center <strong>of</strong> <strong>Weill</strong> <strong>Cornell</strong> Medical Center has<br />

the largest CLL clinical research program in New York,<br />

currently conducting 12 trials. The Leukemia Program<br />

initiated research in the use <strong>of</strong> allogeneic stem cell<br />

transplant for patients with active acute leukemia,<br />

a group <strong>of</strong> patients for which allogeneic transplant<br />

has traditionally not been used. Under Dr. Usama<br />

Gergis’ direction, the division is using a transplant<br />

regimen that includes CPX-351, a novel liposomal<br />

chemotherapeutic agent. Faculty and fellows had<br />

several high-impact publications published in The New<br />

England Journal <strong>of</strong> <strong>Medicine</strong>, Blood, Lancet Oncology,<br />

and the Journal <strong>of</strong> Clinical Oncology.<br />

Our investigators are participants in National<br />

Cancer Institute clinical trials through the Cancer and<br />

Leukemia Group B, the New York Phase II consortium,<br />

and other investigator-initiated NIH- or foundationsponsored<br />

clinical studies. Drs. Rebecca Elstrom,<br />

Peter Martin and Gail Roboz are principal investigators<br />

<strong>of</strong> NCI-sponsored national clinical studies (either<br />

open or in development through the Cancer and<br />

Leukemia Group B) … Dr. Evi Giannakakou has made<br />

very significant strides in the molecular mechanisms<br />

<strong>of</strong> chemotherapeutic resistance, focusing on the<br />

biology <strong>of</strong> microtubules, the molecular target <strong>of</strong><br />

taxane chemotherapy. She has identified a new<br />

mechanism <strong>of</strong> taxane-induced myelosupression and<br />

has applied for a patent … Dr. Peter Martin worked<br />

closely with NYPH to establish a tumor registry that<br />

includes all patients diagnosed with lymphoma.<br />

This retrospective, and now prospective, registry<br />

will enable the division to analyze patients in order<br />

to identify new clinical and biologic prognostic<br />

biomarkers. Clinical databases that prospectively<br />

follow patient cohorts are operational in the leukemia<br />

and myeloma programs … The division received<br />

17 new grants, including seven NIH R01 (or<br />

equivalent level); one R21 grant for clinical<br />

investigation; three nonfederal career awards for<br />

junior investigators; and two subcontracts from<br />

Memorial Sloan-Kettering Cancer Center.<br />

Facilities are undergoing a major upgrade. The<br />

division’s hospital-based oncology and hematology<br />

practices and infusion center are undergoing a major<br />

renovation to create a state-<strong>of</strong>-the-art Center for<br />

Oncology and Hematological Care. New exam room<br />

and practice space opened in January 2011, and<br />

estimated completion for the entire project is 2013.<br />

The GI Oncology Program prepared for its move<br />

into beautifully renovated space on the 12th floor<br />

<strong>of</strong> the <strong>Weill</strong> Greenberg Center – with 11 infusion<br />

bays and 9 exam rooms, the space is a tremendous<br />

opportunity for growth. Active recruitment is<br />

underway for a senior academic GI oncologist and<br />

two junior recruits to occupy the six <strong>of</strong>fices available.<br />

New state-<strong>of</strong>-the-art technology includes:<br />

Flow Cytometer System; HiSeq 2000 and Genome<br />

Analyzer IIx (GAIIx); Axiovert Observer Epifluorescence<br />

microscope, with motorized stage and automated<br />

capabilities to take multiple channels <strong>of</strong> fluorescence,<br />

automated z stacks and deconvoluting capability to<br />

get a clearer single image or 3D perspective, and a<br />

Zeiss camera with optical thresholding for quantitative<br />

analysis; and BD LSR II (Blue laser/Red laser/Yellow-<br />

Green laser/Violet laser/UV laser configuration), which<br />

provides a solid-state Coherent Sapphire 488nm Blue<br />

laser (20mw), a solid-state 640nm Red laser (40mw),<br />

a solid-state 561nm Yellow-Green laser (50mw),<br />

a solid-state 405nm Violet laser (100mw) and a<br />

solid-state 355nm UV laser (20mw) with the ability<br />

to detect two colors from the Blue laser (plus FSC,<br />

SSC), three colors from the Red laser, five colors from<br />

the Yellow-Green laser, four colors from the Violet<br />

laser and two colors from the UV laser. Laser-control<br />

s<strong>of</strong>tware allow the adjustment <strong>of</strong> laser power settings<br />

and monitor key performance parameters <strong>of</strong> the<br />

Coherent lasers.<br />

New recruits and several faculty received<br />

promotions: Doron Betel, PhD, was appointed<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Computational Biomedicine<br />

in <strong>Medicine</strong>, and is Co-Director <strong>of</strong> the Epigenomics<br />

Core with Dr. Ari Melnick …<br />

Paraskevi Giannakakou, PhD, Associate Pr<strong>of</strong>essor<br />

<strong>of</strong> <strong>Medicine</strong>, was elected to tenure in the <strong>Department</strong><br />

<strong>of</strong> <strong>Medicine</strong>, in recognition <strong>of</strong> her accomplishments<br />

in molecular oncology and translational cancer<br />

research … Monica L. Guzman, PhD, was appointed<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Pharmacology in <strong>Medicine</strong>. The<br />

recipient <strong>of</strong> an NIH Director’s New Innovator Award,<br />

Dr. Guzman is a highly promising young investigator<br />

who works to identify specific features <strong>of</strong> malignant<br />

stem cells implicated in leukemia. She works in<br />

close collaboration with Dr. Gail Roboz, a prominent<br />

leukemia clinical investigator, and participates in<br />

a number <strong>of</strong> highly important and collaborative<br />

scientific initiatives … Christopher Hillyer, MD, was<br />

appointed Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> (Courtesy). A faculty<br />

member <strong>of</strong> Emory University and President and CEO<br />

<strong>of</strong> the New York Blood Center, he serves concurrently<br />

as the Chief Officer <strong>of</strong> the Lindsley F. Kimball Research<br />

Institute and the National Cord Blood Program.<br />

Dedicated to worldwide collaboration, academic<br />

scholarship, teaching and mentoring, he continues<br />

to advance the field <strong>of</strong> transfusion medicine. His<br />

current research includes the molecular biology <strong>of</strong><br />

allo- and autoimmune responses to blood transfusion,<br />

massive transfusion for traumatic injuries, transfusion<br />

in regions hyperendemic for malaria, the biology <strong>of</strong><br />

CMV transmission in neonates, and improvement <strong>of</strong><br />

participation by underrepresented minorities in blood<br />

donation programs …Yariv Houvras, MD, PhD, was<br />

appointed Assistant Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> (Secondary<br />

Appointment) and Assistant Attending Physician …<br />

Sebastian Mayer, MD, Assistant Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

and formerly the Division’s Hospitalist, joined the<br />

Bone Marrow Transplant Program … Khine Zin Oo,<br />

MD, was appointed Instructor in <strong>Medicine</strong>, Assistant<br />

Attending Physician, and Hospitalist for the division<br />

… Shakrokh Shariat, MD, was appointed Associate<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> (Secondary Appointment;<br />

Primary Appointment, <strong>Department</strong> <strong>of</strong> Urology).<br />

Dr. Monica Guzman (R)<br />

These discoveries<br />

led to a new<br />

patent <strong>of</strong> a<br />

method to predict<br />

clinical outcomes<br />

in leukemia<br />

patients using<br />

an epigenetic<br />

biomarker.<br />

Annual Report 2011 53


Division <strong>of</strong> Hospital<br />

<strong>Medicine</strong><br />

Arthur T. Evans, MD, MPH<br />

Chief, Division <strong>of</strong> Hospital<br />

<strong>Medicine</strong><br />

Vice Chair <strong>of</strong> Faculty<br />

Development<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Attending Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

The Division <strong>of</strong> Hospital <strong>Medicine</strong> was founded<br />

in the summer <strong>of</strong> 2009 with the arrival <strong>of</strong> Dr. Arthur<br />

Evans, who assumed the role <strong>of</strong> Division Chief after<br />

20 years spent in clinical research, teaching, and both<br />

primary care and hospital-based internal medicine<br />

at Dartmouth, University <strong>of</strong> North Carolina, Rush, and<br />

Cook County Hospital.<br />

The division is dedicated to providing compassionate,<br />

effective, and efficient inpatient medical care and<br />

to advancing the pr<strong>of</strong>ession through education,<br />

innovation, rigorous scientific inquiry, and continuous<br />

learning. With an expansion <strong>of</strong> faculty and services,<br />

the division members are responsible for the daily<br />

care <strong>of</strong> over 100 hospitalized patients. The seven<br />

new faculty members – Drs. Renuka Gupta, Rachel<br />

Dubr<strong>of</strong>f, Anna Maw, Ernie Esquivel, Margaret McNairy,<br />

Won Kim, and Sean Pickering (Assistant Division<br />

Chief) – bring a wealth <strong>of</strong> experience and talent.<br />

Nine <strong>of</strong> the division’s 21 faculty members have<br />

advanced training and degrees beyond board<br />

certification in internal medicine, including medical<br />

ethics, critical care, infectious diseases, emergency<br />

medicine, nephrology, medical informatics,<br />

pediatrics, geriatrics, molecular biology, and clinical<br />

epidemiology. These diverse talents enhance our<br />

commitment to an interdisciplinary approach to<br />

improving systems <strong>of</strong> care in the hospital.<br />

Hospital <strong>Medicine</strong> faculty worked collaboratively<br />

with members <strong>of</strong> the Division <strong>of</strong> Cardiology to<br />

efficiently triage and optimally manage patients<br />

presenting to the Emergency <strong>Department</strong> with chest<br />

pain. Dr. Jennifer Lee has partnered with General<br />

Internal <strong>Medicine</strong> and the Readmission Task Force to<br />

pilot a program to allow early follow-up appointments<br />

for patients without easy access to primary care<br />

immediately after hospital discharge. Dr. Amy Chused<br />

has developed a template to identify patients at high<br />

risk for readmission, with the goal <strong>of</strong> developing<br />

targeted initiatives to lower the risk. Dr. Chin Tang<br />

launched a new program where hospitalists work<br />

in partnership with physician assistants to meet the<br />

growing demand for inpatient clinical services.<br />

Drs. Tang, Gupta, Richard Lin and Heather Cereste<br />

have promoted innovative efforts to enhance<br />

teamwork and communication between nurses<br />

and physicians on the medicine wards.<br />

Under the leadership <strong>of</strong> Dr. Eva Flores, the <strong>Medicine</strong>-<br />

Orthopedics Trauma Service (a multidisciplinary,<br />

co-managed service for the care <strong>of</strong> patients with<br />

concurrent orthopedic injuries and complicated<br />

medical problems) was selected by the Society<br />

<strong>of</strong> Hospital <strong>Medicine</strong> to participate with nine other<br />

centers nationwide to demonstrate models <strong>of</strong><br />

excellence.<br />

The department’s goals <strong>of</strong> improving the quality and<br />

safety <strong>of</strong> patient care are a major focus <strong>of</strong> the division.<br />

As co-chairs, Dr. Jennifer Lee (Hospital <strong>Medicine</strong>) and<br />

Dr. Robert Kim (Cardiology) lead the newly expanded<br />

<strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Quality Improvement and<br />

Patient Safety Program, which works with all divisions<br />

to identify and implement measureable quality<br />

improvement and patient safety initiatives.<br />

Working globally, Dr. Kedar Mate, in association<br />

with the Institute for Healthcare Improvement, is<br />

reorganizing the delivery <strong>of</strong> healthcare in South Africa.<br />

Dr. Lin continues to lead efforts to improve pain<br />

control for inpatients and received a Clinical and<br />

Translational Science Center Planning Award for<br />

pain management research. Drs. Anthony Ogedegbe,<br />

Rachel Dubr<strong>of</strong>f, and Ernie Esquivel are helping to<br />

develop new guidelines for note writing in the era <strong>of</strong><br />

the electronic medical record. The goals are to enhance<br />

communication, reduce medical errors, and facilitate<br />

a safe transition to outpatient care at discharge.<br />

The division continues to play a pivotal role<br />

in the education <strong>of</strong> medical residents, students<br />

and physician extenders. In recognition <strong>of</strong> his<br />

outstanding teaching and for modeling compassionate<br />

pr<strong>of</strong>essionalism, Dr. Sal Cilmi was awarded the<br />

J. James Smith Memorial Award. Dr. Ogedegbe<br />

was acknowledged by the medical school for his<br />

teaching excellence. Dr. Cereste was recognized<br />

for her excellence in teaching medical ethics to<br />

second- and fourth-year medical students.<br />

As Vice Chair for Faculty Development, Dr. Evans<br />

used the results <strong>of</strong> a department-wide faculty<br />

survey to initiate the first phase <strong>of</strong> a novel Faculty<br />

Development Program. The program provides<br />

intensive mentoring to a cadre <strong>of</strong> early-career<br />

faculty using innovative group-based techniques.<br />

The program will be expanded to include a greater<br />

number <strong>of</strong> faculty across all disciplines and all<br />

stages <strong>of</strong> career.<br />

Dr. Richard Lin<br />

The program<br />

provides intensive<br />

mentoring to<br />

a cadre <strong>of</strong> earlycareer<br />

faculty<br />

using innovative<br />

group-based<br />

techniques.<br />

54 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Drs. Pickering (L) and Evans (R)<br />

Annual Report 2011 55


Division <strong>of</strong> Infectious Diseases<br />

The Division <strong>of</strong> Infectious Diseases provides<br />

expertise in research, clinical care and education.<br />

Internationally recognized physician-scientists<br />

conduct cutting-edge basic laboratory and patientoriented<br />

research in infectious diseases, both in<br />

New York City and abroad (Brazil, Haiti, India and<br />

Tanzania). In New York City, active areas <strong>of</strong> research<br />

include bacteriology (including antibiotic-resistant<br />

organisms), bioterrorism, food- and water-borne<br />

pathogens, fungi, hepatitis, HIV/AIDS, hospitalacquired<br />

infections, human papillomavirus, influenza,<br />

leishmaniasis, malaria, transplant/oncology infectious<br />

diseases and tuberculosis. The Division also leads<br />

research and training programs abroad in the areas<br />

<strong>of</strong> HIV/AIDS, HTLV-1, leishmaniasis, syphilis and<br />

tuberculosis. Divisional faculty head the <strong>Weill</strong> <strong>Cornell</strong><br />

Medical College/NewYork-Presbyterian Hospital<br />

Infectious Diseases Inpatient Consult Service, the<br />

HIV/AIDS Program and <strong>Weill</strong> <strong>Cornell</strong> Infectious<br />

Disease Associates, an outpatient practice comprising<br />

Travel <strong>Medicine</strong> and faculty and fellow consultation<br />

services. The Infectious Diseases Fellowship Training<br />

Program includes individualized training through<br />

faculty guidance, clinical rotations, mentored<br />

research and didactic course work to train the<br />

next generation <strong>of</strong> infectious diseases specialists.<br />

Infectious Diseases faculty members also teach<br />

and train medical students, internal medicine<br />

residents and peer physicians in the latest strategies<br />

for diagnosis, management and treatment <strong>of</strong><br />

infectious diseases.<br />

The division celebrated several research milestones.<br />

A study conducted at GHESKIO (its Haitian Center<br />

for the Study <strong>of</strong> Kaposi’s Sarcoma and Opportunistic<br />

Infections) published in The New England Journal<br />

<strong>of</strong> <strong>Medicine</strong> (NEJM) (authors: Drs. Daniel Fitzgerald,<br />

Roy Gulick, Warren Johnson, Jean Pape) showed<br />

that starting antiretroviral therapy earlier in the<br />

course <strong>of</strong> HIV disease is associated with a significant<br />

survival benefit. The results influenced changes in<br />

HIV treatment guidelines worldwide, including those<br />

<strong>of</strong> the World Health Organization.<br />

Division investigators also determined the efficacy<br />

<strong>of</strong> a new, single-dose (intravenous infusion) form<br />

<strong>of</strong> the drug amphotericin B in treating visceral<br />

leishmaniasis. Compared to the standard course <strong>of</strong><br />

treatment, the new treatment was effective, efficient,<br />

and ensured patient compliance. This therapeutic<br />

strategy will likely become the mainstay <strong>of</strong> the<br />

Kala-Azar (leishmaniasis) Elimination Program in<br />

India, where more than half <strong>of</strong> the world’s cases<br />

appear. The study (senior author: Dr. Henry Murray)<br />

was published in the NEJM.<br />

The division’s research in Mycobacterium<br />

tuberculosis resulted in the publication <strong>of</strong> the first<br />

biochemical descriptions <strong>of</strong> TB’s unique metabolic<br />

architecture, including the revelation <strong>of</strong> how it<br />

withstands sterilization. The papers, in Chemistry<br />

& Biology, the Proceedings <strong>of</strong> the National<br />

Academy <strong>of</strong> Sciences and Nature Communications,<br />

also demonstrate the unique potential <strong>of</strong> mass<br />

spectrometry-based metabolomics to both expand<br />

Roy M. Gulick, MD, MPH<br />

Chief, Division <strong>of</strong> Infectious<br />

Diseases<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Attending Physician<br />

NewYork-Presbyterian Hospital<br />

Division <strong>of</strong> Immunology<br />

Kendall A. Smith, MD<br />

Chief, Division <strong>of</strong><br />

Immunology<br />

Rochelle Belfer Pr<strong>of</strong>essor<br />

in <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

The Division <strong>of</strong> Immunology focuses on basic and<br />

clinical research to translate the advances that have<br />

been made over the last 30 years in immunology into<br />

new therapies for immunological disorders. Effort is<br />

ongoing to discover new molecules that can either<br />

suppress or enhance immunoreactivity. We also<br />

remain committed to developing new, more effective<br />

vaccines.<br />

The Division has focused on two research areas:<br />

the generation <strong>of</strong> an effective influenza virus vaccine<br />

that is broadly cross-reactive so that yearly vaccination<br />

would be unnecessary and pandemic influenza<br />

could be aborted; and the identification <strong>of</strong> small<br />

molecular inhibitors <strong>of</strong> transcription factors, which<br />

are important for lymphomas and myelomas, and<br />

also as inhibitors <strong>of</strong> immune reactions for the<br />

treatment <strong>of</strong> autoimmune diseases, hypersensitivity<br />

diseases as well as suppressants <strong>of</strong> allograft rejection.<br />

In the area <strong>of</strong> influenza vaccines we have<br />

successfully provided pro<strong>of</strong> <strong>of</strong> principle in murine<br />

models that vaccines aimed at activating T-cell<br />

immune responses can confer broadly cross-reactive<br />

immunity against virus strains that are not serologically<br />

cross-reactive. Thus, it should be possible to create<br />

“T-cell vaccines” for immunization <strong>of</strong> humans. In<br />

addition, we have data indicating that it should be<br />

possible to apply interleukin-2 as an adjuvant to<br />

boost immune responses so that the vaccine doses<br />

could be attenuated, thus making it possible to<br />

immunize larger numbers <strong>of</strong> people.<br />

We are committed to the education <strong>of</strong> medical<br />

students and <strong>of</strong>fer elective courses such as Host<br />

Defenses, Microbiology and Immunology, and Clinical<br />

Bone Marrow and Stem Cell Transplantation.<br />

Members <strong>of</strong> the Transplantation/Oncology Infectious Diseases Program, left to right: Drs. Michael Satlin, Maria N. Gamaletsou, David Helfgott, Rosemary Soave,<br />

Ruta Petraitiene, Thomas Walsh, and Vidmantas Petraitis<br />

56 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 57


Division <strong>of</strong> Infectious Diseases continued<br />

The Infectious<br />

Diseases<br />

Fellowship Training<br />

Program includes<br />

individualized<br />

training through<br />

faculty guidance,<br />

clinical rotations,<br />

mentored research<br />

and didactic<br />

course work to<br />

train the next<br />

generation<br />

<strong>of</strong> infectious<br />

diseases<br />

specialists.<br />

Dr. Jennifer Downs (Firstprize<br />

winner <strong>of</strong> the DOM<br />

Investigator Award (in 2011)<br />

and recipient <strong>of</strong> the CTSC<br />

second-year, KL2 Scholar<br />

Award in the amount <strong>of</strong><br />

$256,000.<br />

knowledge <strong>of</strong> the basic physiology and accelerate<br />

the TB drug development process. Dr. Kyu Rhee,<br />

an author <strong>of</strong> these papers, was one <strong>of</strong> only nine<br />

grantees in the country to receive further funding<br />

from the Bill & Melinda Gates Foundation, through<br />

the Grand Challenges Exploration Program.<br />

The division launched a Transplant-Oncology<br />

Infectious Diseases Program, which conducts<br />

multidisciplinary translational research in<br />

immunocompromised adult and pediatric patients in<br />

the areas <strong>of</strong> antimicrobial pharmacology, molecular<br />

diagnosis and innate host defenses against medically<br />

important fungal pathogens and emergent drugresistant<br />

bacteria that infect our most vulnerable<br />

patients. Program investigators identified the critical<br />

role <strong>of</strong> antifungal therapy in improving survival in<br />

patients with severe aplastic anemia; described<br />

the pharmacology <strong>of</strong> echinocandin compounds in<br />

infants and lung transplant recipients; and reported<br />

the results <strong>of</strong> a National Heart Lung and Blood<br />

Institute-sponsored study <strong>of</strong> antifungal prophylaxis<br />

in hematopoietic stem cell transplantation recipients.<br />

Papers were published (Dr. Thomas Walsh as senior<br />

or first author) in Clinical Infectious Diseases, Clinical<br />

Pharmacology Therapeutics, Antimicrobial Agents<br />

and Chemotherapy, and Blood.<br />

Infectious Diseases Associates, the outpatient<br />

practice <strong>of</strong> the Division <strong>of</strong> Infectious Diseases,<br />

expanded its hours, hired new staff members, and<br />

continued to add faculty practices that provide<br />

infectious diseases consultations. The Center for<br />

Special Studies (the HIV primary care clinic) joined the<br />

Ambulatory Care Network <strong>of</strong> NewYork-Presbyterian<br />

Hospital. The Center for Global Health secured<br />

a major three-year grant from the Mulago<br />

Foundation to support health innovations at <strong>Weill</strong><br />

Bugando Medical School in Tanzania. The Transplant-<br />

Oncology Infectious Diseases Program inaugurated<br />

its clinical service with the first full-time faculty<br />

(Drs. Rosemary Soave and Thomas Walsh) to support<br />

the Hematopoietic Stem Cell Transplant and Solid<br />

Organ Transplantation NYPH services.<br />

The division hosted the CME course Update on<br />

Infectious Diseases 2010, with presentations by<br />

WCMC faculty Drs. Anne Moscona, Henry Murray,<br />

and Audrey Scheutz; panelists Drs. Barry Hartman,<br />

David Helfgott, and Kristin Marks; and Course<br />

Directors Drs. Marshall Glesby and Roy Gulick, and<br />

attended by over 100 healthcare providers. The<br />

HIV Clinical Trials Unit hosted the Sixth Annual<br />

HIV Update Symposium: Special Populations,<br />

Special Needs – Growing Up with HIV (Dr. Mary<br />

Vogler, Course Director) attended by more than<br />

140 people. The American Austrian Foundation<br />

infectious diseases course was held in Salzburg,<br />

Austria. Divisional faculty (Course Director<br />

Dr. Richard Roberts, and including speakers<br />

Drs. Gulick, Steven Jenkins, and Rosemary Soave)<br />

supported the week-long program attended by more<br />

than 40 Eastern European physicians focusing on<br />

topics such as antibiotics, drug-resistant bacteria,<br />

infections in immunocompromised hosts, influenza,<br />

and tuberculosis. The HIV Clinical Trials Unit hosted<br />

the 13 th Annual CME Conference on Controversies<br />

in the Management <strong>of</strong> the HIV-Infected Patient,<br />

attended by more than 100 health pr<strong>of</strong>essionals<br />

from the tri-state area. Divisional speakers included:<br />

Drs. Glesby, (Course Director), Gulick, (Course<br />

Co-Director), Marks, and Timothy Wilkin. The<br />

Arthur Ashe Endowment for the Defeat <strong>of</strong> AIDS,<br />

directed by Dr. Murray, includes as its centerpiece<br />

the International Healthcare Workers Training<br />

Program in which six other division faculty<br />

participate as instructors.<br />

Collette Kean and the Rollin Browne Fund from<br />

the The Auxiliary <strong>of</strong> New York <strong>Weill</strong> <strong>Cornell</strong> Medical<br />

Center made a generous contribution to upgrade<br />

the divisional conference room to provide state-<strong>of</strong>the-art<br />

audiovisual equipment. Among other things,<br />

the division plans to develop videoconferencing<br />

<strong>of</strong> divisional clinical and research conferences with<br />

participation by fellow faculty at remote sites.<br />

Several new recruits were welcomed to the<br />

division: Drs. Elizabeth Alexander and Jennifer<br />

Downs were recruited from the division’s fellowship<br />

program, both appointed to Instructor in <strong>Medicine</strong>.<br />

Dr. Alexander conducts translational research on<br />

drug-resistant Staphylococcus aureus. Dr. Downs<br />

is based full-time at the <strong>Weill</strong> Bugando Medical<br />

Center in Mwanza, Tanzania, conducting research<br />

in female genital schistosomiasis. Dr. David Calfee,<br />

recruited from Mount Sinai Medical Center, was<br />

appointed to Chief Hospital Epidemiologist at<br />

<strong>Weill</strong> <strong>Cornell</strong>/NewYork-Presbyterian Hospital. He<br />

co-leads a new clinical and research program in<br />

hospital epidemiology and infection control with<br />

Dr. Stephen Wilson, recruited from Indiana University<br />

and appointed to Hospital Epidemiologist. Dr. Andy<br />

Miller was appointed to Assistant Pr<strong>of</strong>essor <strong>of</strong> Clinical<br />

<strong>Medicine</strong>, focusing on clinical infectious diseases at<br />

the Hospital for Special Surgery. Dr. Thomas Walsh<br />

was recruited after serving more than 25 years at<br />

the National Institutes <strong>of</strong> Health to become Director<br />

<strong>of</strong> the newly established Transplantation-Oncology<br />

Infectious Diseases Program.<br />

Division <strong>of</strong> Medical Ethics<br />

Dr. David Berlin (L) with Dr. Fins, Medical Intensive Care Unit.<br />

Joseph J. Fins, MD, FACP<br />

Chief, Division <strong>of</strong> Medical<br />

Ethics<br />

E. William Davis, Jr., M.D.<br />

Pr<strong>of</strong>essor <strong>of</strong> Medical Ethics<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> Public Health<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> in<br />

Psychiatry<br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Director <strong>of</strong> Medical Ethics and<br />

Chair, Ethics Committee<br />

Attending Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

The Division <strong>of</strong> Medical Ethics examines how to<br />

balance competing goods in health care and medical<br />

research. Our goal is to blend disciplinary approaches<br />

from the sciences and medical humanities to promote<br />

patient and subject welfare, foster integrity and<br />

innovation in medical research, and provide the next<br />

generation <strong>of</strong> physicians and biomedical researchers<br />

with the values and analytical skills necessary for<br />

ethical pr<strong>of</strong>essional lives. The Division is located in<br />

both the <strong>Department</strong>s <strong>of</strong> <strong>Medicine</strong> and Public Health,<br />

jointly administered by the two departments.<br />

Clinical faculty members direct a clinical Ethics<br />

Consultation Service at NewYork-Presbyterian/<br />

<strong>Weill</strong> <strong>Cornell</strong> Medical Center to assist clinicians,<br />

patients and their families in assessing and resolving<br />

ethical issues that arise from clinical practice. The<br />

service works with colleagues in the Patient Services<br />

Administration to help elucidate facts and issues,<br />

and resolve misunderstandings, miscommunications,<br />

and conflicts. The Clinical Ethics Consultation<br />

Service consulted on over 185 cases in 2010,<br />

assisting patients, families and staff in analyzing<br />

and mediating difficult decisions and conflicts.<br />

Taking a leadership role in the national arena, the<br />

division has become one <strong>of</strong> the first centers to<br />

credential its medical ethicists, with the support <strong>of</strong><br />

the NewYork-Presbyterian Hospital medical board.<br />

Research initiatives explore a wide range <strong>of</strong> topics<br />

both in the practice <strong>of</strong> medicine and in medical<br />

research, including neuroethics, clinical ethics, end<strong>of</strong>-life<br />

care and ethical issues in reproductive medicine<br />

and genomics. The Ethics Core <strong>of</strong> the medical<br />

Our goal is to blend disciplinary<br />

approaches from the sciences and<br />

medical humanities to promote<br />

patient and subject welfare.<br />

college’s Clinical and Translational Science Center<br />

is available to researchers and subjects to address<br />

issues involving subject rights and safety through the<br />

Research Ethics Consultation Service and Research<br />

Subject Advocacy Program. Members <strong>of</strong> the division<br />

conduct pioneering research in neuroethics,<br />

research ethics in neurology and psychiatry, ethics<br />

case consultation and the ethics <strong>of</strong> molecular<br />

medicine. The division receives funding from the<br />

Clinical and Translational Science Center to direct<br />

the Research Ethics Core.<br />

Medical ethics education is integral to the mission<br />

<strong>of</strong> the division, and all faculty members are involved<br />

in educational initiatives. The division continues to<br />

play a pivotal role in the education <strong>of</strong> our medical<br />

students, providing a longitudinal curriculum here<br />

and in Doha, coordinating the introduction to<br />

Medical Ethics in <strong>Medicine</strong>, Patient, Society II, and<br />

leading the third-year clerkship in ethics and end<strong>of</strong>-life<br />

care, which has been recognized as a singular<br />

curricular <strong>of</strong>fering. A Fellowship in Medical Ethics<br />

has been established by the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

and Rheumatology at the Hospital for Special Surgery<br />

and is being conducted in partnership with the<br />

<strong>Weill</strong> <strong>Cornell</strong> Division <strong>of</strong> Medical Ethics. The division<br />

continued its series <strong>of</strong> monthly seminars for faculty,<br />

students and clinicians with “Ethics, Technology and<br />

Dignity: What 20th-century Philosophy Can Teach<br />

Us about Medical Humanities in the 21st Century”<br />

in 2009 – 10, and for 2010 – 11, “Justice in<br />

<strong>Medicine</strong>: A Philosophical Introduction amidst<br />

Healthcare Reform.”<br />

58 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 59


Division <strong>of</strong> Nephrology and Hypertension<br />

Dr. Suthanthiran’s<br />

Research Group<br />

The Division <strong>of</strong> Nephrology and Hypertension<br />

provides compassionate, comprehensive, state-<strong>of</strong>the-art<br />

care to every patient afflicted with kidney<br />

disease and/or high blood pressure. The <strong>Weill</strong><br />

<strong>Cornell</strong> nephrology program has been consistently<br />

ranked in the top five programs in the country by<br />

U.S. News and World Report, and again in 2010.<br />

The NewYork-Presbyterian Hospital kidney disease<br />

program was ranked fourth, one <strong>of</strong> the highestranked<br />

specialties at NewYork-Presbyterian. The<br />

Hypertension Center is the only center in the greater<br />

New York metropolitan area devoted exclusively<br />

to patients with disorders <strong>of</strong> blood pressure and<br />

circulation.<br />

In November 2010, NewYork-Presbyterian/<br />

<strong>Weill</strong> <strong>Cornell</strong> was one <strong>of</strong> eleven recipients (chosen<br />

from 199 hospitals) <strong>of</strong> the Health Grades Kidney<br />

Transplant Excellence Award. Based on SRTR<br />

calculations, hospitals were recognized for statistically<br />

significantly higher three-year graft survival rates and<br />

waitlist mortality, either not significantly different<br />

than expected or significantly lower than expected.<br />

(Source: SRTR Center and OPO-Specific Report:<br />

www.ustransplants.)<br />

The division’s nephrology program excels in renal<br />

consultation services; dialysis therapy (about 6,000<br />

dialysis procedures per year at the hospital); and<br />

kidney and pancreas transplantation services (more<br />

than 200 kidney transplants per year) with patient<br />

and transplant survival rates superior to U.S. National<br />

Standards. Our faculty have achieved innovations in<br />

transplantation including: making transplant feasible<br />

for high-risk patients; minimizing the amount <strong>of</strong><br />

drugs patients need for successful transplantation;<br />

developing treatment protocols to reduce serious<br />

post-transplant complications, such as infection<br />

and malignancy; and development <strong>of</strong> noninvasive<br />

molecular assays for assessing transplant status and<br />

reducing the need for invasive biopsy procedures.<br />

The division’s clinical care for patients afflicted<br />

with acute or chronic kidney disease is evidence<br />

based. We actively investigate factors predisposing<br />

individuals with hypertension to the development <strong>of</strong><br />

kidney failure. Research pursued by the hypertension<br />

faculty include pregnancy induced hypertension, the<br />

mind-body link in hypertension, and individualized<br />

drug therapy for hypertension control. Ongoing<br />

research has identified a new and treatable mechanism<br />

for kidney injury; we hope to translate our scientific<br />

discovery into clinical practice.<br />

Molecular <strong>Medicine</strong>: The <strong>Weill</strong> <strong>Cornell</strong> Division<br />

<strong>of</strong> Nephrology and Hypertension has pioneered the<br />

development <strong>of</strong> noninvasive gene-based assays to<br />

ascertain transplant status (published in The New<br />

England Journal <strong>of</strong> <strong>Medicine</strong>), previously requiring an<br />

invasive biopsy procedure. The results from our NIHsponsored<br />

molecular studies <strong>of</strong> transplant recipients<br />

were selected for presentation at national (American<br />

Society <strong>of</strong> Nephrology and American Transplant<br />

Congress) and international (The Transplantation<br />

Society) meetings. Our original study, first conducted<br />

at WCMC, has led to an NIH-sponsored multicenter<br />

Cooperative Clinical Trial in Transplantation composed<br />

<strong>of</strong> 750 subjects from major transplant centers in<br />

the United States. Our Gene Expression Monitoring<br />

Laboratory is functioning as the molecular core for<br />

this extensive study. Based on a bench-to-bedside<br />

approach, this study should lead to state-<strong>of</strong>-theart,<br />

individualized care (personalized medicine) <strong>of</strong><br />

transplant recipients.<br />

Transplantation without Immunosuppressive<br />

Therapy: The ultimate goal in organ transplantation<br />

is transplant tolerance, that is, transplantation<br />

<strong>of</strong> organs without any drug therapy. The division<br />

contributed to the first ever report on tolerance<br />

<strong>of</strong> mismatched kidney transplants, which was<br />

published in The New England Journal <strong>of</strong> <strong>Medicine</strong>.<br />

The ability to transplant a human organ without<br />

drug therapy is <strong>of</strong> exceptional significance. In<br />

recognition <strong>of</strong> our contribution, NYP/<strong>Weill</strong> <strong>Cornell</strong><br />

has been selected by the NIH (one <strong>of</strong> three centers<br />

in the U.S. along with Harvard Medical School and<br />

University <strong>of</strong> Pennsylvania) to conduct the innovative<br />

transplant tolerance trials. Recently, we identified<br />

a molecular signature in the urine <strong>of</strong> patients who<br />

are tolerant <strong>of</strong> kidney transplants, the findings<br />

published in The Journal <strong>of</strong> Clinical Investigation.<br />

Our renal fellowship program is highly competitive<br />

with hundreds <strong>of</strong> applications received for the four<br />

available positions every year. We remain dedicated<br />

to educating and training the next generation <strong>of</strong><br />

leading renal and hypertension specialists.<br />

Manikkam Suthanthiran, MD<br />

Chief, Division <strong>of</strong> Nephrology<br />

and Hypertension<br />

Chief, <strong>Department</strong> <strong>of</strong><br />

Transplantation <strong>Medicine</strong> and<br />

Extracorporeal Therapy<br />

Stanton Griffis Distinguished<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> Biochemistry<br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> in Surgery<br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Attending Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

Our original<br />

study, first<br />

conducted at<br />

WCMC, has led to<br />

an NIH-sponsored<br />

multicenter<br />

Cooperative<br />

Clinical Trial in<br />

Transplantation<br />

composed <strong>of</strong> 750<br />

subjects from<br />

major transplant<br />

centers in the<br />

United States.<br />

60 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

Annual Report 2011 61


Division <strong>of</strong> Pulmonary and Critical Care<br />

<strong>Medicine</strong><br />

Ronald G. Crystal, MD<br />

Chief, Division <strong>of</strong> Pulmonary<br />

and Critical Care <strong>Medicine</strong><br />

Chairman, <strong>Department</strong> <strong>of</strong><br />

Genetic <strong>Medicine</strong><br />

Bruce Webster Pr<strong>of</strong>essor <strong>of</strong><br />

Internal <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> Genetic <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Attending Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

The Division <strong>of</strong> Pulmonary and Critical Care<br />

<strong>Medicine</strong> has expertise that is highly skilled in<br />

the diagnosis and treatment <strong>of</strong> patients with all<br />

types <strong>of</strong> breathing or lung disorders, as well as<br />

all disorders related to sleep. Physicians <strong>of</strong> <strong>Weill</strong><br />

<strong>Cornell</strong> Pulmonary Associates provide advanced<br />

diagnostic and therapeutic services in a state-<strong>of</strong>the-art<br />

medical facility. The division provides<br />

24-hour, in-hospital coverage <strong>of</strong> the Medical<br />

Intensive Care Unit and the Medical Step-Down<br />

Unit by both Pulmonary/Critical Care faculty<br />

and fellows. Research interests focus on genetic<br />

medicine – the development <strong>of</strong> strategies for<br />

understanding and modifying gene expression in<br />

the treatment and/or prevention <strong>of</strong> human disease.<br />

Full-time faculty members provide an outstanding,<br />

multifaceted educational program by participating<br />

in the training <strong>of</strong> students, residents, and fellows,<br />

teaching courses, and hosting weekly case<br />

conferences.<br />

It was another year <strong>of</strong> remarkable<br />

accomplishments in clinical care, education,<br />

and research. Clinical programs continued<br />

to flourish. Under the direction <strong>of</strong> Dr. David Berlin,<br />

the Medical Intensive Care Unit (MICU) realized<br />

notable advancements in patient care. Clinical<br />

care in the MICU was further enhanced by<br />

an increase in faculty attending services during<br />

overnight hours. Under the leadership <strong>of</strong><br />

Drs. Olumayowa Abe and Oren Friedman, specialists<br />

in critical care medicine, world-class care was<br />

provided to critically ill patients not only in the MICU<br />

but throughout the hospital through consultation<br />

and procedural services during overnight hours.<br />

Physicians <strong>of</strong> <strong>Weill</strong> <strong>Cornell</strong> Pulmonary Associates<br />

provide advanced diagnostic and therapeutic services<br />

in a state-<strong>of</strong>-the-art medical facility.<br />

The Pulmonary Inpatient Consult Service has<br />

developed into a robust program providing expert<br />

clinical care seven days a week. This service, which has<br />

experienced a significant increase in volume, enhances<br />

the continuity <strong>of</strong> care for patients transitioning<br />

from inpatient to outpatient management and has<br />

led to many clinically successful interdisciplinary<br />

collaborations with specialists throughout the<br />

institution. The division welcomed to the faculty<br />

Dr. Kirana Gudi, whose primary focus is the<br />

further expansion and enhancement <strong>of</strong> the consult<br />

service through the development <strong>of</strong> strong clinical<br />

partnerships throughout the institution.<br />

The Pulmonary Outpatient Service, led by Dr. Dana<br />

Zappetti, has also experienced significant growth<br />

and enhancement, beginning with its relocation to a<br />

new, beautifully appointed, state-<strong>of</strong>-the-art facility in<br />

<strong>Weill</strong> Greenberg Center. Strong emphasis has been<br />

placed on the development <strong>of</strong> a patient-centered<br />

continuum <strong>of</strong> care through which patient services<br />

are coordinated within the division and throughout<br />

the larger health system. The Pulmonary Procedure<br />

Service, under the direction <strong>of</strong> Dr. Ben-Gary Harvey,<br />

has remained cutting-edge by embracing innovations<br />

in diagnostic and treatment services such as “EBUS”<br />

(endo-bronchial ultrasound) for the diagnosis and<br />

staging <strong>of</strong> mediastinal masses, lymphadenopathy and<br />

lung cancer, in addition to traditional bronchoscopy<br />

and laryngoscopy services. The Pulmonary Function<br />

Laboratory, led by Dr. Abraham Sanders, continues as<br />

a vital component <strong>of</strong> the division’s continuum <strong>of</strong> care<br />

by providing expert and timely diagnostic services to<br />

patients throughout the institution.<br />

<strong>Weill</strong> <strong>Cornell</strong>’s newly relocated and expanded,<br />

state-<strong>of</strong>-the-art Center for Sleep <strong>Medicine</strong> (run jointly<br />

by the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong>/Division <strong>of</strong> Pulmonary<br />

and Critical Care <strong>Medicine</strong> and the <strong>Department</strong> <strong>of</strong><br />

Neurology), is staffed by a multidisciplinary team<br />

led by Medical Director Dr. Ana Krieger, expert in<br />

evaluating the full range <strong>of</strong> sleep problems, whether<br />

they arise from an underlying medical problem – such<br />

as sleep apnea or restless leg syndrome – or other<br />

underlying medical and psychiatric conditions,<br />

physical airway obstruction, or from poor sleep<br />

habits, stress or anxiety. Patients treated at the<br />

Center for Sleep <strong>Medicine</strong> are under the care <strong>of</strong><br />

a comprehensive team that includes specialists<br />

in pulmonary medicine, neurology, internal<br />

medicine, ear nose and throat (ENT), pediatrics,<br />

psychiatry, psychology, bariatric surgery, nutrition,<br />

and endocrinology. The Center accommodates<br />

patients for outpatient visits and overnight studies<br />

promptly and at their convenience. Patients are<br />

monitored by use <strong>of</strong> advanced sleep-recording<br />

equipment in private rooms. Because pediatric and<br />

bariatric patients require special care, the center has<br />

sleep study rooms with specialized furniture and<br />

monitoring equipment dedicated to their needs.<br />

By increasing the availability <strong>of</strong> physician services,<br />

the center has been able to accommodate<br />

immediate requests for evaluation, diagnosis<br />

and treatment and has become a provider <strong>of</strong> choice<br />

for patients and referring physicians on a local,<br />

national and international level. The Center welcomed<br />

Dr. Amit Patel to the faculty.<br />

A major focus <strong>of</strong> the division is the expert<br />

training <strong>of</strong> pulmonary and critical care clinical<br />

fellows in all aspects <strong>of</strong> pulmonary and critical care<br />

medicine, including sleep disorders. The division<br />

provides a multifaceted educational program and<br />

maintains a daily schedule <strong>of</strong> intensive teaching<br />

rounds in the MICU with fellows, residents, and<br />

students. Teaching award-winning faculty provide<br />

comprehensive training in pulmonary and critical<br />

care medicine to fellows, residents, and students<br />

through regular lectures, course teaching, and<br />

hosting <strong>of</strong> weekly case conferences.<br />

Dr. Dana Zappetti<br />

62 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

Annual Report 2011 63


Division <strong>of</strong> Rheumatology<br />

Mary K. Crow, MD<br />

Chief, Division <strong>of</strong><br />

Rheumatology<br />

Joseph P. Routh Pr<strong>of</strong>essor<br />

<strong>of</strong> Rheumatic Diseases in<br />

<strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Attending Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

With a 50-year<br />

tradition <strong>of</strong><br />

excellence in<br />

research, the<br />

Division is widely<br />

recognized for<br />

its contributions<br />

to defining<br />

the underlying<br />

mechanisms <strong>of</strong><br />

autoimmune and<br />

musculoskeletal<br />

conditions.<br />

Based at the Hospital for Special Surgery (HSS),<br />

the Division <strong>of</strong> Rheumatology fosters world-class<br />

rheumatology care throughout the York Avenue<br />

institutions; provides autoimmunity and musculoskeletal<br />

education at all levels; and conducts cutting-edge<br />

basic, translational, clinical, and drug trial investigations.<br />

With a 50-year tradition <strong>of</strong> excellence in research, the<br />

Division is widely recognized for its contributions to<br />

defining the underlying mechanisms <strong>of</strong> autoimmune<br />

and musculoskeletal conditions. The rheumatology<br />

training is second to none, developing superb clinical<br />

rheumatologists.<br />

Dr. Mary K. Crow became the Physician-in-Chief<br />

and Chief <strong>of</strong> the Division <strong>of</strong> Rheumatology at HSS in<br />

2010. She is also the Director <strong>of</strong> the Autoimmunity<br />

and Inflammation Program and Co-Director <strong>of</strong><br />

the Mary Kirkland Center for Lupus Research at<br />

HSS. As the new Chief <strong>of</strong> Rheumatology, her vision<br />

emphasizes leadership, innovation, standards,<br />

academic approach, optimal outcomes, opportunities<br />

for faculty advancement, collaboration, and<br />

communication. The emphasis is on disease-focused<br />

Centers <strong>of</strong> Excellence as a mechanism to organize<br />

the division’s clinical care, education, and research<br />

activities. The Systemic Lupus Erythematosus (SLE)<br />

and Antiphospholipid Syndrome (APS) Center <strong>of</strong><br />

Excellence, directed by Dr. Jane Salmon, and the<br />

Inflammatory Arthritis Center, directed by Dr. Sergio<br />

Schwartzman, are well along in their development.<br />

Planning for a Scleroderma, Vasculitis and Myositis<br />

Center <strong>of</strong> Excellence has been initiated, and other<br />

centers will follow. Dr. Crow led the development<br />

<strong>of</strong> a divisional plan that will guide clinical and<br />

academic activities to be incorporated into the<br />

overall Strategic Plan <strong>of</strong> the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong>.<br />

Quality initiatives, led by Steven Magid, MD, are<br />

a high priority and are being recommended by the<br />

Centers <strong>of</strong> Excellence and monitored by hospital<br />

administration. HSS has committed to expanding<br />

the physical space allocated to the Division <strong>of</strong><br />

Rheumatology by 50 percent in the next two years.<br />

Plans are under way for aggregation <strong>of</strong> physician<br />

practices based on disease focus and on consolidation<br />

<strong>of</strong> rheumatology education activities on a designated<br />

education floor.<br />

Academic and research achievements included<br />

the successful competitive renewal <strong>of</strong> a T32 National<br />

Institutes <strong>of</strong> Health Rheumatology Research Training<br />

Grant; election <strong>of</strong> three faculty members – Drs. Stephen<br />

Paget, Steven R. Goldring, and Joseph Markenson –<br />

as Masters <strong>of</strong> the American College <strong>of</strong> Rheumatology;<br />

recruitment <strong>of</strong> a new basic research faculty member,<br />

Dr. Alessandra Pernis, who studies mechanisms<br />

<strong>of</strong> lymphocyte function in systemic autoimmune<br />

diseases, and a new clinical research faculty member,<br />

Dr. Jessica Gordon, who is developing a Scleroderma<br />

Clinic (and pursuing studies <strong>of</strong> new therapies for<br />

patients with scleroderma); and important research<br />

advances related to mechanisms <strong>of</strong> rheumatoid<br />

arthritis and lupus, prediction <strong>of</strong> pregnancy outcomes<br />

in patients with antiphospholipid antibodies, and<br />

testing <strong>of</strong> tyrosine kinase inhibitors in patients with<br />

scleroderma.<br />

HSS scientists were awarded more than<br />

$2.8 million in research grants via the federal<br />

stimulus package (initiated in 2009), funded by the<br />

NIH. Dr. Carl Blobel has been researching ADAM<br />

family metalloproteinases, which play critical roles in<br />

rheumatoid arthritis, and Dr. Jane E. Salmon received<br />

a grant supplement for gene expression studies<br />

in patient samples from her multicenter study on<br />

pregnancy complications and loss in patients with<br />

SLE and APS, and a second grant to examine the<br />

role <strong>of</strong> antiphospholipid antibodies in pregnancy<br />

complications and loss using an animal model <strong>of</strong><br />

APS. Dr. Lionel Ivashkiv furthered his record <strong>of</strong><br />

outstanding NIH support for his studies <strong>of</strong> cytokine<br />

signaling pathways in inflammation with funding<br />

through six R01 research grants.<br />

In developing our disease-focused centers <strong>of</strong><br />

excellence, the division continues to establish links<br />

among basic, translational and clinical research<br />

investigators and providers <strong>of</strong> clinical care.<br />

Dr. Goldring, Chief Scientific Officer, is advancing<br />

the HSS research mission to translate basic science<br />

findings into new ways <strong>of</strong> treating and preventing<br />

inflammatory diseases and musculoskeletal disorders.<br />

A major focus <strong>of</strong> research efforts is the creation<br />

<strong>of</strong> disease registries that will drive improvements<br />

in patient outcomes. Among the division’s current<br />

registries are a multicenter NIH-funded registry <strong>of</strong><br />

biomarkers <strong>of</strong> pregnancy outcomes in patients with<br />

SLE and APS led by Dr. Salmon; a longitudinal lupus<br />

registry that includes disease activity data and DNA,<br />

RNA and serum samples on SLE patients directed by<br />

Drs. Kyriakos Kirou and Crow; a Scleroderma Registry<br />

and Repository directed by Drs. Robert F. Spiera<br />

and Jessica K. Gordon; and a Rheumatoid Arthritis<br />

Registry developed by Dr. Sergio Schwartzman. HSS<br />

has created an Osteoarthritis Initiative to establish an<br />

integrated basic, translational and clinical research<br />

program that focuses on each stage <strong>of</strong> the disease.<br />

Division faculty are collaborating with surgeons who<br />

perform anterior cruciate ligament and total joint<br />

arthroplasty procedures to characterize the molecular<br />

and cellular composition <strong>of</strong> synovial tissue at various<br />

stages <strong>of</strong> OA and relate those results to clinical<br />

manifestations <strong>of</strong> disease.<br />

Additional highlights include: Identification <strong>of</strong><br />

a potential biomarker to define rheumatoid arthritis<br />

patients likely to demonstrate a good response<br />

to TNF antagonist therapies (Dr. Mary K. Crow);<br />

characterization <strong>of</strong> a macrophage signaling pathway<br />

that regulates cytokine responses (Dr. Lionel B. Ivashkiv);<br />

description <strong>of</strong> the gene expression pr<strong>of</strong>ile <strong>of</strong> primary<br />

venous endothelial cells isolated from patients with<br />

SLE (a collaboration <strong>of</strong> Drs. Jane E. Salmon, Mary<br />

K. Crow, and Paolo Colombo, a cardiologist from<br />

The emphasis is on disease-focused Centers <strong>of</strong> Excellence<br />

as a mechanism to organize the division’s clinical care,<br />

education, and research activities.<br />

64 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Dr. Mary Crow<br />

Annual Report 2011 65


Division <strong>of</strong> Rheumatology continued<br />

<strong>Weill</strong> <strong>Cornell</strong> Internal <strong>Medicine</strong> Associates (WCIMA)<br />

The Quality<br />

Research Center<br />

facilitates a<br />

system to gather<br />

and share data<br />

and data sources,<br />

and link quality<br />

outcomes with<br />

laboratory<br />

systems,<br />

demographics<br />

and financial<br />

systems.<br />

(L to R) Drs. Kyriakos Kirou,<br />

Mary Crow, Jane Salmon<br />

Columbia University College <strong>of</strong> Physicians and<br />

Surgeons); development <strong>of</strong> a comprehensive gene<br />

expression and proteomics dataset derived from<br />

analysis <strong>of</strong> longitudinal blood samples from wellcharacterized<br />

lupus patients (Drs. Mary K. Crow and<br />

Kyriakos Kirou); identification <strong>of</strong> lupus anticoagulant<br />

as an informative biomarker <strong>of</strong> pregnancy outcomes<br />

in patients with APS (Drs. Jane E. Salmon and<br />

Michael D. Lockshin); completion <strong>of</strong> the first clinical<br />

study <strong>of</strong> imatinib mesylate (Gleevec), a tyrosine kinase<br />

inhibitor, in a phase II open-label study <strong>of</strong> patients<br />

with scleroderma (Drs. Robert Spiera, Jessica Gordon,<br />

Kyriakos Kirou, and Mary K. Crow); and investigation<br />

<strong>of</strong> outcomes <strong>of</strong> total joint arthroplasty based on data<br />

collected through a collaborative project between<br />

HSS and WCMC <strong>Department</strong> <strong>of</strong> Public Health, funded<br />

by the Agency for Healthcare Research and Quality<br />

Center for Education and Research on Therapeutics<br />

(Dr. Lisa Mandl).<br />

Clinical care <strong>of</strong> patients with rheumatic disease<br />

is implemented through the Mary Kirkland Center<br />

for Lupus Care, the Inflammatory Arthritis Clinic<br />

and the general rheumatology clinic. The lupus<br />

clinic, led by Drs. Doruk Erkan and Kyriakos Kirou,<br />

has incorporated novel approaches to patient<br />

access, including Lupus Fast Track, which facilitates<br />

patient triage to appropriate specialty care.<br />

The center has also developed a unique patient<br />

education program focused on prevention <strong>of</strong><br />

cardiovascular disease. The Inflammatory Arthritis<br />

Clinic, led by Dr. Sergio Schwartzman, incorporates<br />

management <strong>of</strong> patients with rheumatoid arthritis,<br />

psoriatic arthritis and ankylosing spondylitis and is<br />

developing quality indicators and research priorities<br />

relevant to those diseases. As a component <strong>of</strong> the<br />

<strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> and through collaborations<br />

with the <strong>Department</strong> <strong>of</strong> Orthopaedic Surgery, the<br />

Comprehensive Arthritis Program provides medical<br />

and surgical care in one setting for patients who<br />

have a systemic disease with a major musculoskeletal<br />

manifestation, as well as important educational<br />

experiences for residents and fellows. These patients<br />

are at higher risk <strong>of</strong> infection than the typical surgical<br />

patient and are more likely to have cardiovascular<br />

disease and other co-morbidities.<br />

Achieving the highest levels <strong>of</strong> quality care<br />

and patient safety is a high priority at Hospital<br />

for Special Surgery. In support <strong>of</strong> this mission, the<br />

hospital has created a Quality Research Center<br />

with an innovative structure for applying research<br />

methodologies to healthcare quality issues. Under<br />

the direction <strong>of</strong> Dr. Steven K. Magid, the center<br />

brings together physicians, nurses, biostatisticians<br />

and other healthcare pr<strong>of</strong>essionals to work together<br />

on research in patient care quality and safety. The<br />

Quality Research Center facilitates a system to gather<br />

and share data and data sources, and link quality<br />

outcomes with laboratory systems, demographics<br />

and financial systems.<br />

The Division <strong>of</strong> Rheumatology has created an<br />

HSS Education Council, led by Dr. Stephen A. Paget,<br />

which is dedicated to the advancement <strong>of</strong> the highest<br />

quality <strong>of</strong> medical education and educational research<br />

in the areas <strong>of</strong> rheumatology, musculoskeletal<br />

perioperative medicine, and musculoskeletal<br />

disorders. Its goals include: an educational needs<br />

assessment; enhance an educational culture <strong>of</strong><br />

excellence and best practices; ensure that expert<br />

medical care is delivered to every rheumatology<br />

patient; define the structure, content, and conduct <strong>of</strong><br />

medical education; support cutting-edge educational<br />

research; develop world-class scholar-clinicians,<br />

scholar-educators, and scholar-investigators.<br />

Dr. Juliet Aizer was been awarded a Clinician<br />

Scholar Educator Award from the Research and<br />

Education Foundation <strong>of</strong> the American College <strong>of</strong><br />

Rheumatology to develop a curriculum in metabolic<br />

bone disease for training <strong>of</strong> rheumatology fellows.<br />

Dr. Jessica Berman, a previous recipient <strong>of</strong> this<br />

award, continues to advance research in training<br />

and assessment <strong>of</strong> rheumatology trainees through<br />

her development <strong>of</strong> an Objective Structured Clinical<br />

Examination tool and basic musculoskeletal training<br />

modules that incorporate joint anatomy, physical<br />

exam <strong>of</strong> the joints and joint injections.<br />

The Rheumatic Disease Fellowship remains<br />

dedicated to training the academic rheumatology<br />

leaders <strong>of</strong> tomorrow. With in-depth interdisciplinary<br />

training in management <strong>of</strong> both common and rare<br />

autoimmune, inflammatory and musculoskeletal<br />

disorders, combined with a requirement for<br />

completion <strong>of</strong> a basic or clinical research project,<br />

HSS rheumatology fellows are competitive for faculty<br />

positions at leading academic centers. In 2010, the<br />

division successfully competed for renewal <strong>of</strong> its NIHfunded<br />

T32 Rheumatology Research Training Grant,<br />

supporting trainees headed for a career in rheumatic<br />

disease research. Nine adult rheumatology fellows –<br />

three per year <strong>of</strong> the three-year program – and one<br />

or two pediatric rheumatology fellows are accepted<br />

as trainees and gain experience in the outpatient<br />

clinics at HSS and through rotations as rheumatology<br />

consultants at NewYork-Presbyterian Hospital and<br />

Memorial Sloan-Kettering Cancer Center. Dr. Berman<br />

coordinates the educational program for secondyear<br />

medical residents, and Dr. Michael D. Lockshin<br />

is developing a course for <strong>Weill</strong> <strong>Cornell</strong> medical<br />

students on caring for patients with chronic illness.<br />

<strong>Weill</strong> <strong>Cornell</strong> Internal <strong>Medicine</strong> Associates continued<br />

its tradition <strong>of</strong> excellence in primary care and medical<br />

education. Clinical programs, such as a Heart Healthy<br />

curriculum developed and administered by our nursing<br />

staff, were added to the already rich array <strong>of</strong> patient<br />

self-management support activities. Our longstanding<br />

multidisciplinary program in diabetes care resulted in<br />

National Committee for Quality Assurance (NCQA)<br />

recognition for Diabetes Excellence. We anticipate our<br />

NCQA application as a Medical Home will shortly follow.<br />

Renovations begun last year <strong>of</strong> our exam rooms were<br />

completed in 2010 providing state-<strong>of</strong>-the-art patientcentered<br />

equipment in every exam room. Excellence<br />

in the education <strong>of</strong> medical students and residents<br />

continues to distinguish our faculty by leadership<br />

in innovations. Quality initiatives including work on<br />

improving inpatient to outpatient transitions have<br />

been added to our list <strong>of</strong> priorities.<br />

WCIMA reorganized its leadership infrastructure<br />

to enhance staff and provider engagement and<br />

accountability. Dr. Christina Harris joins Dr. Fred Pelzman<br />

as Associate Medical Director. Mission leaders to support<br />

core strategic initiatives were appointed; Dr. Robert Savillo<br />

as clinical leader, Dr. Christina Harris as educational leader,<br />

Dr. Fran Ganz as quality leader, and Dr. Carla Boutin-Foster<br />

as research leader. Area directors were also chosen to<br />

partner with WCIMA staff on practice improvement pilots;<br />

Dr. Johanna Martinez, blue director, Dr. Fred Pelzman,<br />

green director, and Ms. Stasi Lubansky, red director.<br />

New recruits include two joint recruits with the<br />

<strong>Department</strong> <strong>of</strong> Public Health, Tara Bishop, MD and<br />

Matthew Press, MD. Dr. Press recently published “The<br />

Impact <strong>of</strong> Resident Duty Hour Reform on Hospital<br />

Readmission Rates Among Medicare Beneficiaries” in the<br />

Journal <strong>of</strong> General Internal <strong>Medicine</strong>. As new Medical<br />

Director, Travis Gossey, MD has been recruited jointly with<br />

POIS (Physician’s Organization <strong>of</strong> Information Systems).<br />

Carmen Ramis, MD has joined WCIMA after serving as an<br />

experienced clinician educator at St. Vincent’s Hospital.<br />

Dr. Anne Kastor has been appointed as Director<br />

<strong>of</strong> the <strong>Weill</strong> <strong>Cornell</strong> Community Clinic (WCCC).<br />

WCCC is a <strong>Weill</strong> <strong>Cornell</strong> student initiative to provide<br />

care to patients who are under- or uninsured.<br />

WCCC, a robust student service-learning activity<br />

sponsored by a faculty steering committee, operates<br />

out <strong>of</strong> the <strong>Weill</strong> <strong>Cornell</strong> Internal <strong>Medicine</strong> Associates<br />

(WCIMA) practice on Monday evenings. Working<br />

with local social service programs, this clinic provides<br />

an important patient care service for the local<br />

community. Dr. Charles Bardes wrote a chapter, “The<br />

Doctor in Middle Age,” published in the new book<br />

Becoming a Doctor, W.W. Norton & Company, Inc.,<br />

in which doctor-writers share their experiences from<br />

“student to specialist.”<br />

Dr. Ginger Winston was awarded a four-year<br />

Minority Investigator Research Supplement (IRS)<br />

by the NHLBI as part <strong>of</strong> the parent grant, “Small<br />

Changes and Lasting Effects (SCALE).” The<br />

association between body image discrepancy, health<br />

risk knowledge <strong>of</strong> obesity and success with weight<br />

loss will be examined.<br />

The Macy Foundation awarded a 2010 planning<br />

year grant called ITEACH (Integrating Transdisciplinary<br />

Education at <strong>Cornell</strong>/Hunter), a collaboration<br />

between <strong>Weill</strong> <strong>Cornell</strong> Medical College and three<br />

schools <strong>of</strong> Hunter College (Nursing, Public Health,<br />

and Social Work). The proposal is to design and<br />

institute a program <strong>of</strong> integrated, interpr<strong>of</strong>essional<br />

educational experiences involving medical students<br />

and nursing, public health and social work<br />

students with new competencies in collaborative<br />

teamwork. Students will learn the roles <strong>of</strong> different<br />

disciplines to hospital and clinic based care,<br />

community outreach, and interdisciplinary care in the<br />

home setting at a very early point in their training.<br />

<strong>Weill</strong>/<strong>Cornell</strong>-based recipients <strong>of</strong> this grant are<br />

Drs. Carol Storey-Johnson, Byron Demopoulos, and<br />

Joseph Murray.<br />

Judy Tung, MD<br />

Director, <strong>Weill</strong> <strong>Cornell</strong><br />

Internal <strong>Medicine</strong><br />

Associates<br />

Associate Chair <strong>of</strong><br />

Educational Affairs<br />

Associate Director,<br />

Internal <strong>Medicine</strong><br />

Residency Program<br />

Program Director,<br />

Primary Care Track<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong><br />

Clinical <strong>Medicine</strong><br />

<strong>Weill</strong> <strong>Cornell</strong> Medical<br />

College<br />

Assistant Attending<br />

Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

WCCC, a robust<br />

student servicelearning<br />

activity<br />

sponsored by a<br />

faculty steering<br />

committee.<br />

Dr. Carla Boutin-Foster<br />

(table 3rd from R) with<br />

the WCCC team.<br />

66 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

Annual Report 2011 67


Iris Cantor Women’s Health Center<br />

Orli R. Etingin, MD<br />

Director, Iris Cantor Women’s<br />

Health Center<br />

Lisa and Sanford B.<br />

Ehrenkranz Pr<strong>of</strong>essor in<br />

Women’s Health<br />

Pr<strong>of</strong>essor <strong>of</strong> Clinical <strong>Medicine</strong><br />

Pr<strong>of</strong>essor <strong>of</strong> Clinical Obstetrics<br />

and Gynecology<br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Attending Physician<br />

NewYork-Presbyterian<br />

Hospital<br />

The Iris Cantor Women’s Health Center (ICWHC)<br />

<strong>of</strong>fers the most comprehensive array <strong>of</strong> healthcare<br />

services, designed specifically for women, in a<br />

single location in New York City. This facility is<br />

a collaboration between NewYork-Presbyterian<br />

Hospital and <strong>Weill</strong> <strong>Cornell</strong> Medical College.<br />

All <strong>of</strong> the Center’s physicians are full-time faculty<br />

members <strong>of</strong> <strong>Weill</strong> <strong>Cornell</strong> Medical College and<br />

attending physicians at NewYork-Presbyterian<br />

Hospital/<strong>Weill</strong> <strong>Cornell</strong> Medical Center. A team <strong>of</strong><br />

nurses, technicians and other healthcare pr<strong>of</strong>essionals<br />

provide superb coordinated care at the Center.<br />

With more than forty thousand square feet<br />

<strong>of</strong> clinical space occupying four floors under one<br />

ro<strong>of</strong>, women can access prevention, screening and<br />

treatment services in one convenient location. Over<br />

the past year, physicians at the Iris Cantor Women’s<br />

Health Center (ICWHC) continued to provide<br />

comprehensive clinical care to both women and men.<br />

A comprehensive Health Education Resource Center<br />

is also available on-site to educate and empower<br />

women to achieve their optimal level <strong>of</strong> health.<br />

In October, Dr. Cathleen London, a Family <strong>Medicine</strong><br />

practitioner, joined the Center from Boston, where<br />

she maintained a private practice for over ten<br />

years and instructed at Boston University and Tufts<br />

University School <strong>of</strong> <strong>Medicine</strong>.<br />

We continued to assist in the development <strong>of</strong><br />

the Iris Cantor Men’s Health Center, which is slated<br />

to open in summer 2012. Dr. Etingin has been<br />

intimately involved in the planning, fundraising, and<br />

implementation phases. The men’s health practice will<br />

solidify and enhance this primary care practice site<br />

within <strong>Weill</strong> <strong>Cornell</strong> and allow access to more than<br />

seven internists.<br />

Women’s Health sponsored a number <strong>of</strong><br />

community events in 2010. Monthly free-to-thepublic<br />

health education seminars were attended<br />

by more than two hundred community members.<br />

Topics include a wide array <strong>of</strong> health conditions and<br />

patient concerns, including thyroid disease, genetic<br />

testing, cosmetic surgery, memory disorders and<br />

more. A recent seminar highlighted Dr. Mark S. Lachs’<br />

new book, Treat Me, Not My Age, providing helpful<br />

advice for baby boomers and beyond. This year’s<br />

annual Women’s Health Symposium hosted over<br />

350 women in the Citicorp Center, with the topic<br />

“Accentuating the Positive – Small Changes Make Big<br />

Differences.” Drs. Lisa Callahan, Louis Aronne and<br />

Gail Saltz spoke about their respective areas <strong>of</strong> fitness,<br />

weight/nutrition management and stress. Plans<br />

are under way for next year’s symposium to cover<br />

“Nutrition in Menopause.”<br />

Faculty<br />

Members<br />

The 28th Annual Women’s Health Symposium welcomed 350<br />

guests at the Citigroup headquarters.<br />

(L to R) Ms. Charlotte Ford, Mrs. Anita Gotto, Dr. Aronne, Dr. Saltz, Mrs. Joan <strong>Weill</strong>,<br />

Dr. Herbert Pardes (President, NewYork-Presbyterian Hospital), Dr. Callahan, Dr. Orli Etingin<br />

Featured speakers at the event entitled – Accentuate the Positive:<br />

Small Changes, Big Results – included well-known authorities<br />

in their fields: Dr. Louis Aronne, an internationally recognized<br />

obesity specialist and Director <strong>of</strong> the Comprehensive Weight<br />

Control Program (affiliated with NYP/WC); Dr. Lisa Callahan,<br />

a frequently interviewed expert on women’s sports medicine;<br />

and Dr. Gail Saltz, a psychiatrist at <strong>Weill</strong> <strong>Cornell</strong> and regular<br />

contributor for CNN and NBC’s “TODAY” show.<br />

Small Changes Leading to Big Results for Better Health.<br />

68 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 69


<strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Faculty<br />

Pr<strong>of</strong>essors<br />

Ronald D. Adelman, MD<br />

Phyllis August, MD, MPH<br />

Charles L. Bardes, MD<br />

James B. Bussel, MD<br />

Mary E. Charlson, MD<br />

Pamela Charney, MD<br />

David J. Christini, PhD<br />

Ronald G. Crystal, MD<br />

Andrew J. Dannenberg, MD<br />

Richard B. Devereux, MD<br />

Lewis M. Drusin, MD, MPH<br />

Orli R. Etingin, MD<br />

Arthur T. Evans, MD, MPH<br />

Oliver T. Fein, MD<br />

Eric J. Feldman, MD<br />

Joseph J. Fins, MD<br />

Neal E. Flomenbaum, MD<br />

Linda M. Gerber, PhD<br />

Menard M. Gertler, MDCM, DSc<br />

Patricia Giardina, MD<br />

Stanley J. Goldsmith, MD<br />

Antonio M. Gotto, Jr., MD, DPhil<br />

Lorraine J. Gudas, PhD<br />

Roy M. Gulick, MD, MPH<br />

Katherine A. Hajjar, MD<br />

Barbara L. Hempstead, MD, PhD<br />

Evelyn M. Horn, MD<br />

Julianne L. Imperato-McGinley, MD<br />

Jonathan L. Jacobs, MD<br />

Ira M. Jacobson, MD<br />

Stephen G. Jenkins, PhD<br />

Warren D. Johnson, Jr., MD<br />

Harvey Klein, MD<br />

Paul D. Kligfield, MD<br />

Mark S. Lachs, MD, MPH<br />

Jeffrey C. Laurence, MD<br />

John P. Leonard, MD<br />

Bruce B. Lerman, MD<br />

Martin Lipkin, MD<br />

Lia S. Logio, MD<br />

Samuel J. Mann, MD<br />

Aaron J. Marcus, MD<br />

B. Robert Meyer, MD<br />

Anne Moore, MD<br />

Henry W. Murray, MD<br />

Alvin I. Mushlin, MD<br />

Ralph L. Nachman, MD<br />

David M. Nanus, MD<br />

Carl F. Nathan, MD<br />

Peter Michael Okin, MD<br />

Jean W. Pape, MD<br />

Mark S. Pecker, MD<br />

Karl Pillemer, PhD, MA<br />

David N. Posnett, MD<br />

R.A. Rees Pritchett, MD<br />

Shahin A. Rafii, MD<br />

Marcus M. Reidenberg, MD<br />

Brendan M. Reilly, MD<br />

Mary J. Roman, MD<br />

Isadore Rosenfeld, MD<br />

Andrew I. Schafer, MD<br />

Eugenia L. Siegler, MD<br />

Richard T. Silver, MD<br />

David J. Skorton, MD<br />

Kendall A. Smith, MD<br />

James P. Smith, MD<br />

Charles R. Steinberg, MD<br />

Kotha Subbaramaiah, PhD<br />

Manikkam Suthanthiran, MD<br />

Linda T. Vahdat, MD<br />

Alan M. Weinstein, MD<br />

Babette B. Weksler, MD<br />

Marc E. Weksler, MD<br />

Shing-Chiu Wong, MD<br />

Associate Pr<strong>of</strong>essors<br />

Ge<strong>of</strong>frey W. Abbott, PhD<br />

Holly Andersen, MD<br />

Souraya (a.k.a.)<br />

Thurayya Arayssi, MD<br />

Susan Clark Ball, MD<br />

Ge<strong>of</strong>frey W. Bergman, MBBS<br />

Carla Boutin-Foster, MD<br />

David J. Brillon, MD<br />

Carol Capello, PhD<br />

Juan Emilio Carrillo, MD, MPH<br />

Wallace A. Carter, Jr., MD<br />

Adam D. Cheriff, MD<br />

Ellen Chuang, MD<br />

Curtis Leland Cole, MD<br />

Joseph T. Cooke, MD<br />

Byron Paul Demopoulos, MD<br />

Maria T. DeSancho, MD<br />

Ruchuang Ding, MD<br />

Daniel W. Fitzgerald, MD<br />

Christine L. Frissora, MD<br />

Paraskevi Giannakakou, PhD<br />

Marshall Jay Glesby, MD, PhD<br />

Linnie M. Golightly, MD<br />

David E. Guyer, MD<br />

Ben-Gary Harvey, MD<br />

James Paul Hollenberg, MD<br />

Ingrid Hriljac, MD<br />

Nathaniel Hupert, MD, MPH<br />

Erica C. Jones, MD<br />

Robert Jeffrey Kaner, MD<br />

Yoon Kang, MD<br />

Rainu Kaushal, MD<br />

Jason S. Kendler, MD<br />

Lisa M. Kern, MD<br />

Thomas K.C. King, MD<br />

Jorge R. Kizer, MD, MSc<br />

Eliot J. Lazar, MD<br />

Hsiou Chi Liou, PhD<br />

Steven M. Lipkin, MD, PhD<br />

Veronica M. LoFaso, MD<br />

Charles Maltz, MD, PhD<br />

Carol A. Mancuso, MD<br />

Steven M. Markowitz, MD<br />

Ari M. Melnick, MD<br />

Samuel T. Merrick, MD<br />

Shari R. Midoneck, MD<br />

David H. Miller, MD<br />

Robert M. Minutello, MD<br />

Susana R. Morales, MD<br />

Ruben Niesvizky, MD<br />

Roger Niles Pearse, MD, PhD<br />

Fred N. Pelzman, MD<br />

Mark B. Pochapin, MD<br />

Barrie L. Raik, MD<br />

M. Cary Reid, Jr., MD, PhD<br />

Arleen B. Rifkind, MD<br />

Gail J. Roboz, MD<br />

Joseph T. Ruggiero, MD<br />

Abraham Sanders, MD<br />

Diana L. Santini, MD<br />

Robert A. Schaefer, MD<br />

Ellen J. Scherl, MD<br />

Stephen M. Scott, MD, MPH<br />

Tsiporah B. Shore, MD<br />

Rosemary Soave, MD<br />

Carol L. Storey-Johnson, MD<br />

Adam Reed Stracher, MD<br />

Andrew H. Talal, MD, MPH<br />

Mary A. Vogler, MD<br />

Jonathan W. Weinsaft, MD<br />

Suzanne Wenderoth, MD<br />

Timothy Wilkin, MD<br />

Hua Yang, MD<br />

Yuan-Shan Zhu, MD, PhD<br />

Michael A. Zullo, MD<br />

Assistant Pr<strong>of</strong>essors<br />

Josyann Abisaab, MD<br />

Lauren Acinapura, MD<br />

Jason Baker, MD<br />

John Thomas Barnard, MD<br />

Cindy H. Baskin, MD<br />

David Berlin, MD<br />

Doron Betel, PhD<br />

Tara F. Bishop, MD<br />

William B. Borden, MD<br />

Abraham B. Bornstein, MD<br />

Brian Bosworth, MD<br />

Risa Breckman, MSW<br />

Cynthia Bristow, PhD<br />

Juliet Caldwell, MD, BA<br />

David P. Calfee, MD<br />

Julia Cassetta, MD<br />

Heather X. Cereste, MD<br />

Macarthur Charles, MD, PhD<br />

Jim W. Cheung, MD<br />

Harold Chin, MD<br />

Amy E. Chused, MD<br />

Tessa Cigler, MD<br />

Salvatore Cilmi, MD<br />

Heidi P. Cordi, MD<br />

Carl Crawford, MD<br />

Ype P. de Jong, MD, PhD<br />

Randi R. Diamond, MD<br />

Vishal H. Dodia, MD<br />

Niels Dua, MD<br />

Rebecca Elstrom, MD<br />

Ernie L. Esquivel, MD<br />

Brenna Farmer, MD<br />

Dmitriy V. Feldman, MD<br />

Jose L. Fernandez, MD<br />

Edgar Figueroa, MD, MPH<br />

Emily S. Finkelstein, MD<br />

Eva K. Flores, MD<br />

Ann Foley, PhD<br />

Richard R. Furman, MD<br />

Maya Gambarin-Gelwan, MD<br />

Fran A. Ganz-Lord, MD<br />

Flavio G. Gaudio, MD<br />

Joy Gelbman, MD<br />

Usama Gergis, MD<br />

John Travis Gossey, MD<br />

Peter W. Greenwald, MD<br />

Kelly Griffin, MD<br />

Rebekah G. Gross, MD<br />

Kirana Gudi, MD<br />

Renuka Gupta, MBBS<br />

Monica L. Guzman, PhD<br />

Sandra M. Hall-Ross, MD<br />

Alexis Halpern, MD<br />

Christina Elaine Harris, MD<br />

Cathy J. Greene Hatcher, PhD<br />

Caren Heller, MD, MBA<br />

Doodnauth Hiraman, MD<br />

Margaret L. H<strong>of</strong>fman, MD<br />

Hanson Hsu, MD<br />

Vinita E. Jacob, MD<br />

Elizabeth Leef Jacobson, MD<br />

Sian Jones, MD<br />

Sarah Kaplan, MD<br />

Helen Karakelides, MD<br />

Anne S. Kastor, MD<br />

Melissa Dee Katz, MD<br />

Robert J. Kim, MD<br />

Laura Kirkman, MD<br />

Ronald B. Kraft, MD<br />

Ana C. Krieger, MD<br />

Trine Krogh-Madsen, PhD, MSc<br />

Charles O. Kwon, MD<br />

Troy LaBounty, MD<br />

Maureen E. Lane, PhD<br />

Richard I. Lappin, MD, PhD<br />

Gina LaRocca, MD<br />

Keith A. LaScalea, MD<br />

Meredith F. Lash-Dardia, MD<br />

Taryn Yeon S. Lee, MD<br />

Jennifer I. Lee, MD<br />

John (Jay) M. Lemery, MD<br />

Richard Liebowitz, MD<br />

Sophia Lin, MD<br />

Fay Yu-Huei Lin, MD<br />

Richard J. Lin, MD, PhD<br />

Mei-Ling Liou, PhD<br />

Christopher F. Liu, MD<br />

Cathleen G. London, MD<br />

Mai A. Mahmoud, MBBS<br />

Tomer M. Mark, MD<br />

Kristen M. Marks, MD<br />

Peter Martin, MD<br />

Johanna Martinez, MD<br />

Bassem M. Masri, MD<br />

Kedar S. Mate, MD<br />

Sebastian Mayer, MD<br />

Margaret L. McNairy, MD<br />

Sonal S. Mehta, MD<br />

Joseph P. Mele, MD<br />

Carlyle H. Miller, MD<br />

James K. Min, MD<br />

Renu Chawla Mital, MD<br />

Thangamani Muthukumar, MD<br />

Nancy N. Nealon, MD<br />

Allyson J. Ocean, MD<br />

Anthony Ogedegbe, MD<br />

Sonja Olsen, MD<br />

Lucy N. Painter, MD<br />

Amit Vinod Patel, MD<br />

Robert N. Peck, MD<br />

Janey C. Peterson, EdD<br />

John Pfeifer, MD<br />

Erica G. Phillips, MD<br />

Sean P. Pickering, MD<br />

Ian Pinto, MBBS<br />

Elizabeta C. Popa, MD<br />

Zoran Popmihajlov, MD<br />

Matthew J. Press, MD<br />

Jane Prosser, MD<br />

Pouneh Kermani<br />

Rabbany, PhD, MSc<br />

Bharathi Raman, MD<br />

Carmen M. Ramis, MD<br />

Sharda D. Ramsaroop, MD<br />

Rama B. Rao, MD<br />

Kyu Young Rhee, MD, PhD<br />

Ellen Ritchie, MD<br />

Eric A. Rosenberg, MD<br />

Jia Ruan, MD, PhD<br />

Mirella Salvatore, MD<br />

Savreet Sarkaria, MD<br />

Robert L. Savillo, MD<br />

Joseph M. Scandura, MD, PhD<br />

Ronald J. Scheff, MD<br />

Bryan J. Schneider, MD<br />

Felice Schnoll-Sussman, MD<br />

Audrey Schuetz, MD<br />

Aaron P. Schulman, MD<br />

Marco Seandel, PhD, MD<br />

Sam Senturia, MD<br />

Rita Shaknovich, MD, PhD<br />

Shahrokh Shariat, MD<br />

Rahul Sharma, MD<br />

Harjot K. Singh, MD<br />

Naina Sinha, MD<br />

Duane M. Smith, MD<br />

Vivian Sobel, MD<br />

Irina Sobol, MD<br />

Jeremy Sperling, MD<br />

Dora J. Stadler, MD<br />

Carolyn Robb Steinberg, MD<br />

Michael E. Stern, MD<br />

Massimiliano Szulc, PhD, MS<br />

Scott Tadashi Tagawa, MD<br />

Chin C. Tang, MD<br />

Kenneth Teng, PhD<br />

George Thomas, MD<br />

Ann Tilley, MD<br />

Judy Tung, MD<br />

Carlos M. Vaamonde, MD, MS<br />

Mohamud Verjee, MBChB<br />

Jaclyn Van Lieu Vorenkamp, MD<br />

Thomas J. Walsh, MD<br />

Luise L. Weinstein, MD<br />

Stephen Wilson, MD<br />

Ginger J. Winston, MD<br />

Franklin J. Wong, MD<br />

Jennifer K. Wright-McCarthy, MD<br />

Cecilia J. Yoon, MD<br />

David A. Zackson, MD<br />

Dana Zappetti, MD<br />

Instructors<br />

Olumayowa Abe, MBBS<br />

Maria Aini, MD<br />

Elizabeth L. Alexander, MD<br />

William J. Ameres, PA-C, BS<br />

Caitlin Anderson, MD<br />

Valerie Antoine-Gustave, MD<br />

Philip Baird, MD<br />

Satchit Balsari, MBBS<br />

Gary J. Bouchard, PhD, PA-C<br />

Amanda S. Carmel, MD<br />

Leandro Cerchietti, MD<br />

Karis Cho, MD<br />

Jennifer A. Downs, MD<br />

Rachel P. Dubr<strong>of</strong>f, MD<br />

Mamoon M. Elbedawi, MBBS<br />

Ronald Englert, DO<br />

Maria E. Figueroa, MD<br />

Oren A. Friedman, MD<br />

Hina Ghory, MD<br />

Elizabeth Haskins, MD<br />

Rachana Jani, MD<br />

Won Kim, MD<br />

Thomas Lee, MD<br />

Michelle Lieberman Lubetzky, MD<br />

Jacqueline Mahal, MD<br />

Anna Myint Maw, MD<br />

Alia (a.k.a.) Maria Menezes, MD<br />

Raffaele Milizia, MD<br />

Zarina Motorwala, MD<br />

Oksana Ocheretina, PhD<br />

Matthew T. O’Neill, MD<br />

Khine Zin Oo, MBBS<br />

Anjali Tripathi Pant, MD<br />

Manisha Patel, MD<br />

Mayra Ramirez, MA, PA-C<br />

Lawrence Siegel, MD<br />

Vishwas A. Singh, MD<br />

Jonathan St. George, MD<br />

Dean Straff, MD<br />

Medea Y. Valdez, PA-C, BS<br />

Michael J. Vortmann, MD<br />

Jonathan A. Waitman, MD<br />

Robert Wilson, MD<br />

Natasha Withers, DO<br />

Christine Zink, MD<br />

Gerardo L. Zullo, MD<br />

Network, Affiliate,<br />

Voluntary, and Emeritus<br />

Faculty<br />

Theophine Abakporo, MBBS<br />

Omar I. Abdel-Wahab, MD<br />

Ahmad Salih Abdulhadi, MBChB<br />

Michael L. Abott, MD<br />

Ghassan Khaled Abou-Alfa, MD<br />

Ali Aboufares, MD<br />

Ursino S. Abucay, MD<br />

Niraj N. Acharya, MBBS, MD<br />

Katafan Achkar, MD<br />

Alberto M. Acosta, MD, PhD<br />

Dana Spivak Adler, MD<br />

Om Parkash Aggarwal, MBBS<br />

Carol A. Aghajanian, MD<br />

Jugal Agrawal, MBBS, MD<br />

Mohammad Abdul Ahad, MBBS<br />

Meena Ahluwalia, MBBS<br />

Hisham Abdul Aleem Abdul<br />

Ahmed, MBChB<br />

Juliet B. Aizer, MD<br />

Corina E. Akerele, MD<br />

Olakunle Akinboboye, MBBS<br />

David P. Akman, MD<br />

Safaa Hassan Ali Al Azewei, MBChB<br />

Salih Ali A. Hadi Al Marri, MBBCh<br />

Abdulwahab Al Musleh, MD<br />

Ibrahim Yousif Mahmood Al Omary,<br />

MBChB<br />

Buthina Ibrahim Al Owainati, MBBS<br />

Ibrahim Al Shaar, MBBCh<br />

Hussam Al Soub, MBBS<br />

Jassim Al Suwaidi, MBChB<br />

Jameela Al-Khowaiter Al-Ajmi, MD<br />

Ahmed A.R. Muhamad Al-Ani,<br />

MBChB<br />

Rafid Fayadh Mohammed Al-Aqeedi,<br />

MBChB<br />

Salah Abdul Aziz Al-Azab, MBBCh<br />

Khalid Al-Badr, MD<br />

Alaa K. Al-Badran, MBChB<br />

Ralph A. Baer, MD<br />

Michael H. Alderman, MD<br />

Louis M. Aledort, MD<br />

Samar Al-Emadi, MBBS<br />

Mushtak Talib Abbas Algherbawe,<br />

MBChB<br />

Abdulzaiz A. Al-Hashemi, MBBS<br />

Waleed Muhsin Ali, MBChB<br />

Rana Ali, MBBS<br />

Sawsan H. Al-Izzi, MBChB<br />

Abdullatif Mohamed Alkhal, MBChB<br />

Robert Allan, PhD<br />

Mona Hass Al-Langawi, MBBS<br />

John P. Allegrante, MS, PhD<br />

Muna A.S. Almaslamani, MBBS<br />

Abdelrahman Almasri, MBBCh<br />

Ahmed A.A. Al-Mohammed, MBBCh<br />

Azza Awad Al-Mujalli, MD<br />

Noora Ahmad Al-Mutawa, MBChB<br />

Abdulrahman D. Alnabti, MD<br />

Saad Abdulfatah A. Al-Nuaimi,<br />

MBChB<br />

Reynaldo H. Alonso, MD<br />

Mourhege M. Al-Saloum, MD<br />

Hashim Mohamed Al-Sayed, MBBCh<br />

Suryanarayan Anand, MBBS<br />

Nanarao Anandarao, MBBS<br />

Suzanne Anderson, MD<br />

Francis P. Arena, MD<br />

Carlos O. Arevalo, MD<br />

Farhad Arjomand, MD<br />

Louis J. Aronne, MD<br />

Jodh S. Arora, MD, MBBS<br />

Pablo A. Arteta, MD<br />

David R. Artz, MD, MBA<br />

Vijaypal Arya, MBBS<br />

Nidal Ahmed Asaad, MBBS<br />

Amanda Falick Ascher, MD<br />

70 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 71


Network, Affiliate, Voluntary, and Emeritus Faculty continued<br />

Dalit Ashany, MD<br />

Muhammad Asim, MBBS<br />

Deborah S. Asnis, MD<br />

Frederick Ast, MD<br />

TuTu Aung, MBBS<br />

Sulaiman Azeez, MBBS<br />

Christopher Gerard Azzoli, Jr., MD<br />

Philip Baird, MD<br />

Dean F. Bajorin, MD<br />

Wallace Baker, MD<br />

Jean Balzora, MD<br />

Deepa Bangalore, MBBS<br />

Juliet Barker, MBBS<br />

David Barlas, MD<br />

Christopher L. Barley, MD<br />

Jeremiah A. Barondess, MD<br />

Peter R. Barra, MD<br />

Alberto O. Barroso, MD<br />

Dorota Bartniczuk, MD<br />

Amanda W. Basford, MD<br />

Baquar Bashey, MBBS, MD<br />

Zelaikha Mohsin Bashwar, MBBS<br />

Riyad J. Basir, MBChB<br />

Anne R. Bass, MD<br />

Paul M. Basuk, MD<br />

Michael Seth Baum, MD<br />

Carol Grossman Baum, MD<br />

Thomas L. Baxter, III, MD<br />

Shamim A. Begum, MBBS<br />

Garth A. Beinart, MD<br />

Rita Bellevue, MD<br />

Paul C. Bellman, MD<br />

Katherine Bell-McGuinn, PhD, MD<br />

Ethan S. Ben-Sorek, MD<br />

Kalman J. Berenyi, MD<br />

Barbara J. Berger, MD<br />

Jack J. Berger, MD<br />

Ivan Bergstein, MD<br />

Samarth Beri, MD<br />

Israel Berkowitz, MD<br />

Arnold Berlin, MD<br />

Ellin Berman, MD<br />

Jessica Berman, MD<br />

Nathaniel Berman, MD<br />

Allan E. Beyda, MD<br />

Rekha Bhandari, MBBS<br />

Thayyullathil Bharathan, MBBS<br />

Kiran K. Bhat, MBBS<br />

Bhaswati Bhattacharya, MD, MPH<br />

Harry Bienenstock, MD<br />

Robert H. Birkhahn, MD<br />

Richard B. Birrer, MD<br />

Rachel D. Bishop, MD<br />

Ana L. Blackmon, MD<br />

James A. Blake, MD<br />

Carl P. Blobel, MD, PhD<br />

Jon David Blumenfeld, MD<br />

David S. Blumenthal, MD<br />

Mitchell J. Blutt, MD<br />

Richard S. Bockman, MD, PhD<br />

Morton D. Bogdon<strong>of</strong>f, MD<br />

Roxana M. Bologa, MD<br />

J. Scott Bomann, DO, BA<br />

Joseph Bonanno, DO, BS<br />

Marc L. Boom, MD, MBA<br />

Lisa Borg, MD<br />

George Joseph Bosl, MD<br />

Joseph Bove, MD<br />

Norman Brachfeld, MD<br />

Terence M. Brady, MD<br />

Barry D. Brause, MD<br />

Melvin Breite, MD<br />

Sorin J. Brener, MD<br />

Peter T. Brennan, MD<br />

Renier J. Brentjens, MD, PhD<br />

Donald Briscoe, MD<br />

Neil M. Brodsky, MD<br />

Jacqueline Francoise<br />

Bromberg, MD, PhD<br />

Mark S. Brower, MD<br />

Arthur E. Brown, MD<br />

John L. Brown, Jr., MD<br />

Robert S. Brown, Jr., MD, MPH<br />

Matthew L. Buchalter, MD<br />

John Buergler, MD<br />

Daniel Arthur Burton, MD<br />

Mohammed Tariq Butt, MBBS<br />

Ahmar A. Butt, MBBS<br />

Daniel J. Byrns, MD<br />

Magdalena Cadet, MD<br />

Lisa Rowland Callahan, MD<br />

Annamaria Calleo-Cross, BS, DO<br />

Robert D. Campagna, MD<br />

Salvatore J. Cannizzo, MD<br />

Michael C. Cantor, MD<br />

Elizabeth Capezuti, PhD, MSN<br />

Ralph Carmel, MD<br />

Philip Charles Caron, MD, PhD<br />

Richard Carvajal, MD<br />

Edgar Marcelino Carvalho<br />

Filho, MD, PhD<br />

David B. Case, MD<br />

Ephraim S. Casper, MD<br />

Ann Castello, MD<br />

Hugo R. Castro-Malaspina, MD<br />

Silvio Ceccarelli, MD<br />

Andrea Cercek, MD<br />

Hakim Chalabi, MD<br />

Sarat Chandarlapaty, MD, PhD<br />

Pradeep Chandra, MBBS<br />

Su Min Chang, MD<br />

Woo-Taek Chang, MD<br />

Michael L. Chang, MD<br />

Raymond Yeesung Chang, MD<br />

Fang Chang, MD, PhD<br />

Paul B. Chapman, MD<br />

Antoine V. Charles, MD<br />

Richard Charney, MD<br />

Chaim Charytan, MD<br />

Bansidhar M. Chauhan, MBBS<br />

Mohit Chawla, MD<br />

Jhoong S. Cheigh, MD, MS<br />

James Chevalier, MD<br />

Karis Cho, MD<br />

Allen Chodock, MD<br />

Edward Won Choi, MD<br />

Charles L. Christian, MD<br />

James P. Christodoulou, MD<br />

Paul J. Chrzanowski, MD<br />

Sedgundina N. Chua-Gan, MD<br />

Penelope Chun, MD<br />

Miriam Chung, MD<br />

David J. Chung, MD, PhD<br />

Bayard D. Clarkson, MD<br />

J. Marietta Clewing, MD<br />

Alana Cohen, MD<br />

Barry A. Cohen, MD<br />

Richard P. Cohen, MD<br />

Symra A. Cohn, MD<br />

Morton Coleman, MD<br />

Lara M. Colton, MD<br />

Rick Conetta, MD<br />

Bradley A. Connor, MD<br />

John Cooke, MD<br />

Robert B. Cooper, MD<br />

Engracio P. Cortes, MD<br />

Steven J. Corwin, MD<br />

Mary K. Crow, MD<br />

Ward F. Cunningham-Rundles, MD<br />

Dana M. Cutzu, MD<br />

Lisa M. Czanko, MD<br />

Wafer Amen Kasim Dabdoob, MD<br />

Clifford C. Dacso, MD, MPH<br />

David R. D’Adamo, MD, PhD<br />

Darshana M. Dadhania, MD<br />

Jane Daly, MD<br />

Gabriella M. D’Andrea, MD<br />

Chau T. Dang, MD<br />

Jean Pratt Daniel, MD<br />

Daniel C. Danila, MD<br />

James Darling, MD<br />

Lloyd A. Darlow, DMD, MD<br />

Malay Das, MBBS<br />

Anita R. Datta, MD<br />

Amish S. Dave, MD, PhD<br />

Yonette Davis, MD<br />

James Davis, MA<br />

Giovanni de Simone, MD<br />

Barbara Ann DeBuono, MD, MPH<br />

Julian A. Decter, MD<br />

Mary L. DelMonte, MD<br />

Moutaz Derbala, MBBCh, MD<br />

Sylvie D. DeSouza, MD<br />

Adam Deutsch, MD<br />

Gerard Devas, MBBS<br />

Lekshmi Dharmarajan, MBBS<br />

Maura N. Dickler, MD<br />

Bruno F. DiCosmo, MD<br />

Hajir Ely Dilmanian, MD<br />

Christopher J. DiMaio, MD<br />

Stephen J. DiMartino, MD, PhD<br />

Vihren Dimitrov, MD<br />

Leonard DiRe, MD<br />

Joshua A. Donis, MD<br />

Alan Dosik, MD<br />

David C. Dosik, MD<br />

Harvey Dosik, MD<br />

R. Gordon Douglas, Jr., MD<br />

James J. Doyle, MD<br />

Ashley L. Drews, MD<br />

Joseph Claude Dreyfus, III, MD<br />

Joan H.F. Drosopoulos, PhD<br />

Natalie J. Dryden, MD<br />

William M. Duke, MD<br />

Elinor Greenspun Dulit, MD<br />

Mark Dursztman, MD<br />

Timothy C. Dutta, MD<br />

Murray Dworetzky, MD<br />

Jay M. Edelberg, MD, PhD<br />

Brian R. Edlin, MD<br />

William T. Edwards, MD<br />

Petros Efthimiou, MD<br />

Barbara C. Egan, MD<br />

John F. Eichelberger, MD<br />

Cristiano Eirale, MD<br />

Howard B. Eison, MD<br />

Isam El Bagi, MBChB<br />

Mohamed Ezzat El Beheary, MBBCh<br />

Abdel Haleem Ahmed<br />

El Hiday, MBBS<br />

George C. Ellis, MD<br />

Ayman A. El-Menyar, MBBCh<br />

Marie Eloi-Stiven, MD<br />

Elhadi Elouzi, MBBCh<br />

Abdul M.T. El-Qawasameh, MBBCh<br />

Mohamed S. El-Tawil, MBBCh<br />

Roger Ira Emert, MD<br />

Angie M. Eng, MD<br />

Ronald Englert, DO<br />

Gulchin A. Ergun, MD<br />

Doruk Erkan, MD<br />

Henry R. Erle, MD<br />

Irina V. Erlikh, MD<br />

Mehdi Mohammed Errayes, MBBS<br />

Atilla Ertan, MD<br />

Susan M. Escudier, MD<br />

Maria T. Espejo, MD<br />

Jorge I. Esquivel, MD<br />

Jerry D. Estep, MD<br />

David G. Evelyn, MD, MPH<br />

Monte Ezratty, MD<br />

James A. Fagin, MD<br />

Thomas J. Fahey, Jr., MD<br />

Victor Fainstein, MD<br />

Samya Ahmed Falamerzi, MBBS<br />

George A. Falk, MD<br />

Albert Fano, MD<br />

Azeez Farooki, MD<br />

Arthur E. Feinerman, MD<br />

Leonard Feingold, MD<br />

Marc B. Feinstein, MD<br />

Darren Feldman, MD<br />

Stuart Feldman, MD<br />

David Feldshuh, MD<br />

Michael J. Feltovich, MD<br />

John Fernandez, MD<br />

Lauren Ferrante, MD<br />

Frederick J. Feuerbach, III, MD<br />

Theodore R. Fields, MD<br />

Stanley R. Fine, MD<br />

Wilmore B. Finerman, Jr., MD<br />

Scott A. Fink, MD<br />

Jeremy Paul Finkelstein, MD<br />

Christopher J. Finnila, MD<br />

Jeffrey D. Fisher, MD<br />

Laura L. Fisher, MD<br />

Edward Flaschner, MD<br />

Robert Fleming, MD<br />

Gloriande Fleurimont, MD<br />

Carlos D. Flombaum, MD<br />

Rebecca L. Florsheim, MD<br />

John T. Flynn, MD<br />

Arthur L. Forni, MD<br />

Monica N. Fornier, MD<br />

Susan C. Fox, MD<br />

Andrew Francella, MD<br />

Joseph A. Franciosa, MD<br />

Richard H. Frankel, DPM<br />

Kenneth W. Franklin, MD<br />

John E. Franklin, Jr., MD<br />

Mark G. Frattini, MD, PhD<br />

James Dermot Frengley, MBChB, MS<br />

Mark S. Friedman, MD<br />

Samuel Friedman, MD<br />

Erika Friedmann, PhD<br />

Todd M. Friend, DO<br />

Abraham Fruchter, MD<br />

Nancy S. Fu, MD<br />

Richard M. Fuchs, MD<br />

Matthew G. Fury, PhD, MD<br />

Jacobo Futran, MD<br />

Theodore J. Gaeta, DO, MPH<br />

Marina Gafanovich, MD<br />

Fiona E. Gallahue, MD<br />

Marilyn Galler, MD<br />

Ronald W. Galluccio, MD<br />

Boris Gambarin, MD, PhD<br />

Sandhya G. Ganti, MBBS<br />

Sandy B. Ganz, DSc, BS<br />

Aaron Garber, MD<br />

Delfino Garcia, III, MD<br />

Christopher Garrett, MD<br />

Bruce A. Garrison, MD<br />

Mitchell L. Gaynor, MD<br />

Abdurrazzak Gehani, MBBCh<br />

Mitchell Geizhals, MD<br />

Brian D. Gelbman, MD<br />

Robert M. Gelfand, MD<br />

Jeremiah Gelles, MD<br />

Edward P. Gelmann, MD<br />

Richard L. Geltman, MD<br />

Ronnie Alan Gentry, MD<br />

Liziamma George, MBBS<br />

Paul Gerardi, MD<br />

Hans Gerdes, MD<br />

John Frank Gerecitano, MD, PhD<br />

Joel R. Gernsheimer, MD<br />

Janet A. Gershengorn, PhD<br />

Wisam K. Ghadban, MBBCh<br />

Issa Mousa Ghanem, MBBCh<br />

Allan Gib<strong>of</strong>sky, MD<br />

Holly Gilbert, MD<br />

Teresa Ann Gilewski, MD<br />

Monica Girotra, MD<br />

Ellen Spielman Gitler, MD<br />

Joel S. Gitlin, MD<br />

Paul A. Glare, MBBS, MD<br />

Robert H. Glassman, MD<br />

Clifford F. Glatzer, MD<br />

Ilya G. Glezerman, MD<br />

Michael S. Glickman, MD<br />

David L. Globus, MD<br />

Isaiarasi Gnanasekaran, MBBS<br />

David H. Goddard, MD, MBBS<br />

Joshua M. Gold, MDCM, PhD<br />

Seth Goldbarg, MD<br />

Harvey L. Goldberg, MD<br />

Jenna Dey Goldberg, MD<br />

Robert S. Goldblatt, MD<br />

Flavia A. Golden, MD<br />

Owen Golden, MD<br />

Ronald A. Golden, MD<br />

Grigoriy Goldenberg, MD, PhD<br />

Shari Goldfarb, MD<br />

Daniel Goldin, MD<br />

Howard Goldin, MD<br />

Steven R. Goldring, MD<br />

Natalya Goldshteyn, MD<br />

Jonas Goldstone, MD<br />

Stephanie M. Goodman, DO<br />

Susan M. Goodman, MD<br />

Bruce R. Gordon, MD<br />

Jessica K. Gordon, MD<br />

George W. Gorham, MD<br />

Richard S. Gottfried, MD<br />

Benjamin V.G. Gozun, MD<br />

Venera Grasso, MD<br />

Michele G. Greene, DrPH<br />

Irina Gressel, MD<br />

William R. Griffo, MD, PhD<br />

Kevin A. Grimes, MD, MPH<br />

Jeffrey S. Groeger, MD<br />

Harry L. Gruenspan, MD, PhD<br />

Gregory Grunberg, MD<br />

Madhav A. Gudi, MBBS<br />

Rebecca S. Guest, MD<br />

Kim A. Guishard, MD<br />

Subhash C. Gulati, MD, PhD<br />

Ramesh S. Gulrajani, MBBS<br />

Shellie Gumbs, MD<br />

Sanjey Gupta, MD<br />

Gregory Miner Gustafson, MD<br />

Neil A. Halpern, MD<br />

Brian Halpern, MD<br />

Nachida Hamidi-Sitouah, MD<br />

Dale J. Hamilton, MD<br />

Bruce Hamilton, MBChB<br />

Paul Anthony Hamlin, MD<br />

Costas Hanjis, MD<br />

George Haralambou, MD<br />

Robert B. Harooni, MD<br />

Melanie Jane Harrison, MD<br />

Catherine C. Hart, MD<br />

Barry J. Hartman, MD<br />

Choli Hartono, MD<br />

Debra K. Harvey, MD<br />

Kristen A. Harvey, MD<br />

Shaikh Hasan, MBBS<br />

Nadyabanu Hasham, DO<br />

Elizabeth Haskins, MD<br />

Azza Adel Ibrahim Hassan,<br />

MBBCh, PhD<br />

Hani Hassoun, MD<br />

Thomas L. Hau, MD<br />

Joseph G. Hayes, MD<br />

Kirsten Healy, MD<br />

Mark Lawrence Heaney, MD, PhD<br />

David C. Helfgott, MD<br />

Arthur D. Heller, MD<br />

William F. Heneghan, MD<br />

Karen Hennessey, MD<br />

Martee L. Hensley, MD<br />

Lawrence L. Herman, MD<br />

Edmund M. Herrold, MD, PhD<br />

Robert Hesson, MD<br />

Christopher D. Hillyer, MD<br />

Jules Hirsch, MD<br />

Yashar Hirshaut, MD<br />

Stuart E. Hisler, MD<br />

Alan Loh Ho, MD, PhD<br />

Melvin C. Hochman, MD<br />

Magdelena Hohn, MD<br />

Wesley P. Hollomon, MD, MBA<br />

Peter R. Holt, MD<br />

John W. Hon, DO<br />

Thomas E. Hong, MD<br />

Lisa A. Honkanen, MD<br />

Jaleh E. Hoorfar-Nathan, DPM<br />

Steven M. Horwitz, MD<br />

Karlene Hosford, MD<br />

Alan N. Houghton, MD<br />

Katherine C. Hsu, PhD, MD<br />

John T. Hsueh, BM<br />

Willa Hsueh, MD<br />

Xiaoyu Hu, BM, PhD<br />

Zheng-Bo Huang, BM<br />

Lisa Cooper Hudgins, MD<br />

Clifford Alan Hudis, MD<br />

I-Lo Hung, MD, MS<br />

James R. Hurley, MD<br />

Barry N. Hyman, MD<br />

Chul Soo Hyun, PhD, MD<br />

Frank Michael Iacovone, Jr., MD<br />

Abdulsalam Saif Ibrahim, MBBS<br />

Wanis Hamad Ibrahim, MBBCh<br />

David H. Ilson, PhD, MD<br />

Barton Inkeles, MD<br />

Lawrence A. Inra, MD<br />

Muhammad Z. Iqbal, MBBS<br />

Lisandro Irizarry, MD, MPH<br />

Lionel B. Ivashkiv, MD<br />

Richard A. Jackson, MD<br />

Robert E. Jackson, MD<br />

Tranice D. Jackson, MD<br />

Matteethra C. Jacob, MD<br />

Michael Jacobson, MD<br />

Alan H. Jaffe, MD<br />

Eric A. Jaffe, MD<br />

Ann A. Jakubowski, MD, PhD<br />

Morris L. Jampol, MD<br />

Yelena Janjigian, MD<br />

Fernando Jara, MD<br />

Charles I. Jarowski, Jr., MD<br />

Robert Ray Jenq, MD<br />

Anil K. John, MBBS<br />

Erik Kent Johnson, MD<br />

Michelle N. Johnson, MD<br />

Edith I. Jones, MD<br />

Thomas C. Jones, MD<br />

Elaine Josephson, MD<br />

George J. Juang, MD<br />

Joseph G. Jurcic, MD<br />

Alan B. Kadet, MD<br />

Samuel K. Kajubi, MBChB, MD<br />

Marcia F. Kalin, MD<br />

Jeffrey E. Kalina, MD<br />

George Kalliolias, MD<br />

Anna Kaltsas, MD<br />

Mini Kamboj, MBBS<br />

Mazen Kamen, MD<br />

Ahmad Abd. El Moniem Kamha,<br />

MBBCh<br />

Lewis Jay Kampel, MD<br />

Aladdin Kanbour, MBChB<br />

72 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 73


Network, Affiliate, Voluntary, and Emeritus Faculty continued<br />

S. Balavenkatesh Kanna, MBBS<br />

Barry H. Kaplan, MD, PhD<br />

Morrie A. Kaplan, MD<br />

Rana Kaplan, MD<br />

Attallah Kappas, MD<br />

Stephen R. Karbowitz, MD<br />

Abdool Salim Karim, MBChB, MS<br />

Amin H. Karim, MBBS<br />

Simon G. Kassabian, MBChB, MD<br />

Moiz M. Kasubhai, MBBS<br />

Lawrence Alton Katz, MD, MPH<br />

Noah D. Kauff, MD<br />

Martin M. Kay, MD<br />

Saka A. Kazeem, MD<br />

Raymond S. Keller, MD<br />

Seth Keller, MD<br />

David P. Kelsen, MD<br />

Nancy E. Kemeny, MD<br />

Robert Owen Kenet, MD, PhD<br />

Denis J. Keohane, MD<br />

David J. Kerr, MD, PhD<br />

Todd Kerwin, MD<br />

Srinivas Kesanakurthy, MBBS<br />

Sandra Kesh, MD<br />

George J. Kessler, DO<br />

Amsale Ketema, MD<br />

Muayad Kasim Khalid, MBChB<br />

Abdul-Jabbar Asim Khan, MBBS<br />

Azeem Khan, MD, MBBS<br />

Fahmi Yousef Khan, MBBS<br />

Farida Khan, MBBS<br />

Izzat Khanjar, MD<br />

Galina Kharash, MD<br />

Dirar Shafiq Khoury, PhD<br />

Timothy E. Kiehn, PhD<br />

Back Kim, MD<br />

Chung Eun Kim, MD<br />

Robin S. Kim, MD<br />

Susan Kim, MD<br />

Woo Sup Kim, BM<br />

Yong Rak Kim, MD<br />

Kyriakos A. Kirou, MD, DSc<br />

Neal S. Kleiman, MD<br />

Ludwig Klein, MD<br />

William A. Klepack, MD<br />

Harold N. Klestzick, DO<br />

Virginia M. Klimek, MD<br />

Adam David Klotz, MD<br />

Barry J. Klyde, MD<br />

Zoulficar A. Kobeissi, MD<br />

Drew Koch, DO<br />

Guenther Koehne, MD, PhD<br />

Iosif Kolbovsky, MD<br />

Richard N. Kolesnick, MD<br />

Mary Kollakuzhiyil, MBBS<br />

Vasantha Kumari Kondamudi, MBBS<br />

Jason Konner, MD<br />

Douglas J. Koo, MD, MPH<br />

Edward Koppel, MD<br />

Beatriz Korc-Grodzicki, MD, PhD<br />

Anthony F. Korosi, MD<br />

Constantine E. Kosmas, MD, PhD<br />

Gamil S. Kostandy, MBChB<br />

Emanuel L. Kouroupos, MD<br />

Elizabeth Kozora, PhD<br />

Lawrence S. Kraftowitz, MD<br />

Robert C. J. Krasner, MD<br />

Daniel Krauser, MD<br />

Mary Jeanne Kreek, MD<br />

Mark G. Kris, MD<br />

Muthuswamy Krishnamurthy, MBBS<br />

Sarada Krishnamurthy, MBBS<br />

Padmanabhan Krishnan, MBBS<br />

Lee M. Krug, MD<br />

Bernard M. Kruger, MD<br />

Anuradha Kumar, MBBS<br />

Chhavi B. Kumar, MD<br />

Suresh Kumar, MBBS, MD<br />

Karla M. Kurrelmeyer, MD<br />

Robert C. Kurtz, MD<br />

Karen LaFace, MD<br />

Eseng Lai, MD, PhD<br />

Diana Lake, MD<br />

Nicole Lamanna, MD<br />

Arnon Lambroza, MD<br />

Heather J. Landau, MD<br />

Thomas K. Landau, MD<br />

Brian R. Landzberg, MD<br />

Edith J. Langner, MD<br />

Stephan C. Lansey, MD<br />

Jose R. Lapa e Silva, PhD, MD<br />

Janice L. Lau, MD<br />

Adam Law, MBBS, MD<br />

Mark J. Leber, MD<br />

Marvin A. Leder, MD<br />

Jun Lee, MD<br />

Robert P. Lee, MD<br />

Thomas Lee, MD<br />

David Lefkowitz, MD<br />

Daniel E. Lehane, MD<br />

Monika J. Leja, MD<br />

Herbert S. Lempel, MD<br />

Nikoletta Lendvai, MD<br />

Paul J. Leo, DO<br />

Michael Richard Leonard, MD<br />

Alfred Ba Tun Leong, MBBS<br />

Alexander M. Lesokhin, MD<br />

Wai L. Leung, MD<br />

Jay M. Levat, MD<br />

Lali Levi, MD<br />

Lawrence F. Levin, MD<br />

Ross L. Levine, MD<br />

Suzanne Marin Levine, DPM<br />

Carol J. Levy, MD<br />

Margaret Lewin, MD<br />

Daniel M. Libby, MD<br />

Warren B. Licht, MD<br />

Amy Dale Lichtenfeld, MD<br />

Stuart M. Lichtman, MD<br />

Lilli B. Link, MD<br />

Stephen H. Little, MD<br />

Frank Ming-Shi Liu, MD<br />

Philip O. Livingston, MD<br />

Michael D. Lockshin, MD<br />

Bruce D. Logan, MD<br />

Raghu S. Loganathan, MBBS<br />

George Vincent Lombardi, MD<br />

Gerard T. Lombardo, MD<br />

Juanita Lo-Ngeo, MD<br />

Olivia A. Lopez, MD<br />

Jorge A. Lopez-Ovejero, MD<br />

Daniel Louis Lorber, MD<br />

Jonathan Lorch, MD<br />

Emmy Ludwig-Miller, MD<br />

Preston Lurie, MD<br />

Jasminder Luthra, MD<br />

Joseph H. Ma, MD<br />

Luis R. Maceira-Rodriguez, MD<br />

C. Ronald MacKenzie, MD<br />

Nicholas T. Macris, MD<br />

Norman M. Magid, MD<br />

Steven K. Magid, MD<br />

Richard J. Mahler, MD<br />

John J. Mahmarian, MD<br />

Vicky Makker, MD<br />

Mariam Abdul Malik, MBBS<br />

Lisa A. Mandl, MD, MPH<br />

Debra A. Mangino, DO<br />

Jack M. Mann, MD<br />

AnnaRita Marcelli, MD<br />

Joseph A. Markenson, MD<br />

Arnold Jay Markowitz, MD<br />

Martin H. Markowitz, MD<br />

Paul A. Marks, MD<br />

Stephen J. Marks, MD<br />

Franklin Marsh, Jr., MD<br />

William A. Martimucci, MD<br />

George T. Martin, MD<br />

Melissa Martin, MD<br />

Andrew Martorella, MD, MS<br />

Robert J. Mascitelli, MD<br />

Peter G. Maslak, MD<br />

Issa Matar, MBChB<br />

Matthew J. Matasar, MD<br />

S. Anjani D. Mattai, MD<br />

Nirmal K. Mattoo, MBBS<br />

Jacqueline Mayo-Morris, MD<br />

Eileen P. McAleer, MD<br />

Heather L. McArthur, MD<br />

John J. McCarthy, MD<br />

Moira Kathleen McCarty, MD<br />

Michael R. McDevitt, PhD<br />

Carl J. McDougall, MD<br />

John C. McKechnie, MD<br />

Philip E. McPherson, MD<br />

Allen W. Mead, MD<br />

John-Paul Mead, MD<br />

Parag Mehta, MBBS, MD<br />

Kenneth R. Meisler, DPM<br />

Jennifer A. Meller, MD<br />

Adrianne H. Mellos, MD<br />

Ellen M. Mellow, MD<br />

Lawrence A. Melniker, MD<br />

Jay Ivan Meltzer, MD<br />

Laura Melville, MD<br />

Antonio Mendez, MD<br />

Charis Fan-Hui Meng, MD<br />

Raymond D. Meng, MD, PhD<br />

Chandra Menon, MBBS<br />

Jean-Paul Menoscal, MD<br />

Frank V. Meriano, MD<br />

Frank Messineo, MD<br />

David B. Messinger, MD<br />

Jennifer K. Meyer, MD<br />

Mark L. Meyer, MD<br />

Fausto S. Meza, MD<br />

Spyros G.E. Mezitis, MD, PhD<br />

Rameen M. Miarrostami, MD<br />

Ollie S. Miettinen, MD, PhD<br />

Andy O. Miller, MD<br />

Susan M. Miller, MD<br />

Vincent Amory Miller, MD<br />

Nancy E. Mills, MD<br />

Matthew Ivan Milowsky, MD<br />

Paul F. Miskovitz, MD<br />

Subhada Mithilesh, MBBS<br />

Abraham M. Mizrahi, MD<br />

Shanu Modi, MD<br />

Vinuta Mohan, MD<br />

Ana Maria Molina, MD<br />

Thomas G. Molnar, MD<br />

Abdul S. Mondul, MD<br />

Donald E. Moore, MD<br />

Michael J. Morris, MD<br />

Natalie Moryl, MD<br />

Lori J. Mosca, MD, PhD<br />

Jeffrey W. Moses, MD<br />

Eliot P. Moshman, MD<br />

Alison Moskowitz, MD<br />

Craig H. Moskowitz, MD<br />

Robert J. Motzer, MD<br />

Emmanuel N. Moustakakis, MD<br />

Lawson A. Moyer, III, MD<br />

Mary Ellen Moynahan, MD<br />

Richard L.P. Mueller, MD<br />

Brigitte Mueller-Morel, MD<br />

James E. Muntz, MD<br />

John Munyak, MD<br />

Skender Murtezani, MD<br />

Elizabeth C. Muss, MD<br />

Amy T. Mynderse, MD<br />

Faisal Nabi, MD<br />

Viswanathan Nagarajan, MBBS<br />

Jerry Nagler, MD<br />

Sherif F. Nagueh, MBBCh<br />

Parathasarathy Narasimhan, MD<br />

Laurie Claire Nash, MD<br />

Thomas W. Nash, MD<br />

George M. Nassar, MD<br />

Sam N. Natarajan, MD<br />

Ethan A. Natelson, MD<br />

Devi Navamani, DO<br />

Asha D. Nayak, MBBS<br />

Kotresha H. Neelakantappa, MBBS<br />

Deena J. Nelson, MD<br />

Christopher L.B. Nevins, MD<br />

Barney D. Newman, MD<br />

Kaman Ng, MD<br />

Kenneth K. Ng, MD<br />

Julie C. Nguyen, MD<br />

Thuyen T. Nguyen, MD<br />

Jeffrey N. Nichols, MD<br />

John P. Nicholson, Jr., MD<br />

Susan C. Nicholson, MD<br />

Aryel Nicoleau, MD<br />

Carl Andre Nicoleau, MD, PhD<br />

Stephen David Nimer, MD<br />

Rudolph H. Nisi, MD<br />

Larry Norton, MD<br />

Michelle K. Nowak-Logozzo, MD<br />

Ariela Noy, MD<br />

Parirokh Nozad, MD<br />

Steve Esfandiar Nozad, MD<br />

Michel Ernest Nussbaum, MD<br />

Irwin Nydick, MD<br />

Martin Nydick, MD<br />

Roisin O’Cearbhaill, MBBCh<br />

Herbert F. Oettgen, MD<br />

Kenneth Offit, MD, MPH<br />

Adesuwa Okesanya, MD<br />

Ion Oltean, MD<br />

Anas Ahmed Omer, MBChB<br />

Kenneth Ong, MD<br />

Eileen M. O’Reilly, MBBCh<br />

Carlos M. Orrego, MD<br />

Aneta Ostrowska, MD<br />

Laszlo Osvath, MD<br />

Vellore T. Padmanabhan, MD<br />

Stephen A. Paget, MD<br />

Joseph Thomas Paglia, MD<br />

Jeffrey E. Paley, MD<br />

Maria Lia Palomba, MD<br />

Eric G. Pamer, MD<br />

Justin Paoloni, MBBS<br />

Esperanza B. Papadopoulos, MD<br />

Genovefa A. Papanicolaou, MD<br />

Benoit Jerry Papon, MD<br />

Chong H. Park, MD<br />

Sonal Shah Parr, MD<br />

Edward J. Parrish, MD<br />

Mark W. Pasmantier, MD<br />

Mina Pastagia, MD<br />

Raymond D. Pastore, MD<br />

Stephen M. Pastores, MD<br />

Arunbhai G. Patel, MD<br />

Harish J. Patel, MBBS<br />

Hirmanshu A. Patel, MBBS<br />

Naveena Pathmakumar, MBBS<br />

Doru Paul, MD<br />

George W. Pelebecky, Jr., MD<br />

Miguel-Angel Perales, MD<br />

Orlando Perales, MD<br />

Jose A. Perez, Jr., MD<br />

Alan S. Perlman, MD<br />

Francis S. Perrone, MD<br />

Lynne V. Perry-Bottinger, MD<br />

Ralph E. Peterson, MD<br />

Manana Petrov, MD<br />

David Gerard Pfister, MD<br />

Patricia Phan, MD<br />

Maria C. Pietanza, MD<br />

Anush S. Pillai, DO, BA<br />

Riccardo Pini, MD<br />

Heidi M. Pinkert, MD<br />

John Pizzolla, MD<br />

Martin Poliak, MD<br />

Doris M. Ponce, MD<br />

Jovan M. Popovich, MD<br />

Carol S. Portlock, MD<br />

John A. Posey, Jr., MD, PhD<br />

Rock Gerard Positano, DPM<br />

David H. Posner, MD<br />

Martin R. Post, MD<br />

Craig M. Pratt, MD<br />

Jacek J. Preibisz, DMSc, MD<br />

Joanna M. Preibisz, MD<br />

Luminita Pricop, MD<br />

Fernando Arturo Pujol-Morato, MD<br />

Miguel A. Quinones, MD<br />

Sina Y. Rabbany, PhD<br />

Michael R. Rabinowitz, MD<br />

Stephen H. Rabinowitz, MD<br />

Michael Stavros Radeos, MD, MPH<br />

Allen Robert Radin, MD<br />

Arthur I. Radin, MD<br />

Russell N. Rad<strong>of</strong>f, MD<br />

Linda Radomski, MD<br />

James J. Rahal, MD<br />

Ali Rahil, MBBCh<br />

Ritesh Raichoudhury, MD<br />

Marwan Ramadan, MBChB<br />

Ramya Ramakrishnan, MD<br />

Dharmarajan Ramaswamy, MBBS<br />

Gumpeni Rammohan, MBBS<br />

Elizabeth Ramos, MD<br />

Dragos Rancea, MD<br />

James A. Rand, MD<br />

Suhail Rao<strong>of</strong>, MBBS<br />

Kakil Ibrahim Rasul, MBChB<br />

Dana Rathkopf, MD<br />

Kanwar S. Rauhila, MBBS<br />

Carroll A. Rayner, MD<br />

Tasleem Raza, MBBS<br />

Rose A. Recco, MD<br />

Steven G. Reed, PhD<br />

Abdul Rehman, MBBS<br />

J. Douglas Reich, MD<br />

Lilian M. Reich, MD<br />

Steven F. Reichert, MD<br />

Bonnie S. Reichman, MD<br />

Diane Reidy-Lagunes, MD<br />

Daniel Reingold, JD<br />

Marshal Scott Reminick, MD<br />

Michael T. Rendel, MD<br />

Gene D. Resnick, MD<br />

Charles M. Rice, PhD<br />

Lawrence Rice, MD<br />

Jack Richard, MD<br />

Jill M. Rieger, MD<br />

Gregory J. Riely, MD, PhD<br />

Robert R. Riggio, MD<br />

Lee Woodland Riley, MD<br />

Deborah L. Rimler, MD<br />

Edgardo Rivera, MD<br />

Naiyer A. Rizvi, MD<br />

Keith W. Roach, MD<br />

Christopher P. Robben, MD<br />

Laura Robbins, DSW<br />

Richard J. Robbins, MD<br />

William C. Robbins, MD<br />

Richard B. Roberts, MD<br />

Mark E. Robson, MD<br />

Arnold M. Rochwarger, MD<br />

John S. Rodman, MD<br />

A. Arturo Rodriguez, MD, MBA<br />

Steven A. Rogers, MD<br />

Nancy Roistacher, MD<br />

Herman Rosen, MD<br />

Neal Rosen, MD, PhD<br />

Howard E. Rosenberg, MD<br />

Peter M. Rosenberg, MD<br />

Todd Rosenblat, MD<br />

Michael A. Rosenbluth, MD<br />

Albert M. Ross, MD<br />

Gary E. Rothbart, MD<br />

Debasish Roychoudhury, MBBS<br />

Marina Rozenberg, MD<br />

David Scott Rubin, MD<br />

Howard S. Rubin, MD<br />

Moshe Rubin, MD<br />

Linda A. Russell, MD<br />

Carlo Russo, MD<br />

James G. Ryan, MD<br />

Mary T. Ryan, MD<br />

Mabel M. Ryder, MD<br />

Stuart D. Saal, MD<br />

Paul Joseph Sabbatini, MD<br />

Reza Sabet, MD<br />

Ian L. Sachs, MD<br />

Michel Sadelain, MD, PhD<br />

Nagham D. Sadik, MBChB<br />

R. Benjamin Saldana, DO<br />

Anthony Saleh, MD<br />

Mansoura Fawaz Salem, MBChB<br />

Jane E. Salmon, MD<br />

Leonard B. Saltz, MD<br />

Lori Beth Saltzman-Gabelman, MD<br />

Cori Salvit, MD<br />

Lisa R. Sammaritano, MD<br />

Tobias C. Samo, MD<br />

Nelson Sanchez, MD<br />

Donna Sandidge, MD<br />

Jean T. Santamauro, MD<br />

Thomas Santucci, Jr., MD<br />

Housam Aldeen Sarakabi, MD<br />

Barry I. Saul, MD<br />

Craig Sauter, MD<br />

Charles L. Sawyers, MD<br />

Wendy Schaffer, MD, PhD<br />

Liviu Schapira, MD<br />

Elaine J. Schattner, MD<br />

Mark A. Schattner, MD<br />

Jonathan Harry Schatz, MD<br />

David Schechter, MD<br />

David A. Scheinberg, MD, PhD<br />

Howard I. Scher, MD<br />

Lawrence Scherr, MD<br />

Andrew N. Schiff, MD<br />

David Ross Schifter, MD<br />

Ralph E. Schlossman, MD<br />

Michael J. Schmerin, MD<br />

H. Alan Schnall, MD<br />

William J. Schneider, MD, MPH<br />

Steven J. Schneider, MD<br />

Melissa P. Schori, MD<br />

George Schroth, MD<br />

Eliot Schuster, MD<br />

Leonard H. Schuyler, MD<br />

Ernest Schwartz, MD<br />

Fred S. Schwartz, MD<br />

Gary K. Schwartz, MD<br />

Joseph S. Schwartz, PhD<br />

Natalie Star Schwartz, MD<br />

Simeon Schwartz, MD<br />

Sergio Schwartzman, MD<br />

John C. Sciales, MD<br />

Richard F. Sc<strong>of</strong>ield, MD<br />

Corey J. Scruggs, MD<br />

Jean E. Sealey, DSc<br />

Neil H. Segal, MD, PhD<br />

Sorana Segal-Maurer, MD<br />

Andrew D. Seidman, MD<br />

Susan Seo, MD<br />

Kent A. Sepkowitz, MD<br />

74 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 75


Network, Affiliate, Voluntary, and Emeritus Faculty continued<br />

Joshua D. Septimus, MD<br />

David Serur, MD<br />

Sandra L. Sessoms, MD<br />

Kenneth K. Sha, MBBS<br />

Nehad Shabarek, MD<br />

Alpesh R. Shah, MBBS<br />

Dipan J. Shah, MD<br />

Manish A. Shah, MD<br />

Monika Kanu Shah, MD<br />

Rajendra C. Shah, MBBS<br />

Nooruldin F. Shakir, MBBS<br />

Benson H. Shalette, MD<br />

Neil F. Shallish, MD<br />

Jerome B. Shapiro, MD, PhD<br />

Neil H. Shapiro, MD<br />

Atul Sharma, MD<br />

Manish Sharma, DO<br />

Pradeep Sharma, MBBS<br />

Vijay Kumar Sharma, PhD<br />

Nitya Sharma (Srinivasan), MD<br />

Gillian M. Shepherd, MD<br />

Stanley Sherbell, MD<br />

Bruce E. Sherling, MD<br />

Eric J. Sherman, MD<br />

Raymond L. Sherman, MD<br />

Christopher P. Shields, MD<br />

Moshe Shike, MD<br />

Maurice E. Shils, MD, DSc<br />

Rony Y. Shimony, MD<br />

Tiana Shiver, MD<br />

Morris A. Shor<strong>of</strong>sky, MD<br />

Meenal Shukla, MBBS<br />

Abdul Rahim M. Siam, MBBS<br />

Jonathan Siegal, MD<br />

Steven E. Siegel, MD<br />

Vasilios Sierros, MD<br />

Samuel H. Sigal, MD<br />

Lyra Sihra, MD<br />

Steven H. Silber, DO<br />

Jeffrey I. Silberzweig, MD<br />

Todd L. Simon, MD<br />

Amit Singh, MD<br />

Ghansham Singh, MD<br />

Dinesh Chandra Sinha, MD, MBBS<br />

Steven Jay Siskind, MD<br />

Diane M. Sixsmith, MD<br />

Nancy T. Sklarin, MD<br />

Alexander J. Slotwiner, MD<br />

Susan Faith Slovin, MD, PhD<br />

Paul T. Smith, MD<br />

Stephanie M. Smith, MD<br />

Charles Smithen, MD<br />

Alan G. Snart, MBBS, MD<br />

Benny S<strong>of</strong>fer, MD, MBA<br />

Won Sohn, MD<br />

David B. Solit, MD<br />

Meyer N. Solny, MD<br />

Henry A. Solomon, MD<br />

Anthony A. Somogyi, MD<br />

Anita Soni, MBBS<br />

Prabhat Soni, MBBS<br />

Girish M. Sonpal, MBBS<br />

Alan J. Sonsky, MD<br />

Julio E. Sotelo, MD<br />

Allison Spatz, MD<br />

Gabriel Spergel, MD<br />

Harry Spiera, MD<br />

Robert Forman Spiera, MD<br />

Bruce S. Spinowitz, MD<br />

Irving M. Spitz, MD<br />

David R. Spriggs, MD<br />

Emmanuel L.G. St. Louis, MD<br />

Stacy Stabler, MD, PhD<br />

Zs<strong>of</strong>ia K. Stadler, MD<br />

Martin Stallone, MD<br />

Lawrence E. Stam, MD<br />

Ioannis A. Stathopoulos, MD, PhD<br />

Randy Stein, MD<br />

Herman Steinberg, MD<br />

Richard M. Steingart, MD<br />

Kurt H. Stenzel, MD<br />

Richard Stern, MD<br />

Mark Y. Stoeckle, MD<br />

Diane E. Stover, MD<br />

Mitchell S. Strand, MD<br />

David J. Straus, MD<br />

Joan A. Stroud, MD<br />

Sheena G. Stubbers, MD<br />

Alison E. Suarez, MD<br />

Steven M. Sugarman, MD<br />

Chang Ho Suk, MD<br />

Mohammed Abd El-Sattar Suliman,<br />

MBChB<br />

John F. Sullivan, MD<br />

Sung Wu Sun, BM<br />

Arthur W. Sung, MD<br />

Wei Fun Sung, MD<br />

Ranjit Suri, MBBS<br />

George C. Surla, MD<br />

Lynn Swisher, MD<br />

Andrew J. Szabo, MD<br />

John L. Szalyga, MD<br />

M. Javad Tabaee-Zadeh, MD<br />

George E. Taffet, MD<br />

Avraham Tal, MD<br />

Kenneth C. Tam, MD<br />

Steve C. Tam, MD<br />

Silvio Robert Tasso, MD<br />

Ying Taur, MD, MPH<br />

William John Tenet, MD<br />

Jeffrey Tepler, MD<br />

Mark J. Tessler, MD<br />

William Tew, MD<br />

Maria Theodoulou, MD<br />

George E. Thibault, MD<br />

Carolyn H. Thompson, MD<br />

Roma Tickoo, MBBS<br />

Jitendra Tolia, MBBS<br />

Alexander Tomasz, PhD<br />

Emily S. Tonorezos, MD<br />

Frantz Torchon, MD<br />

Guillermo Torre-Amione, MD, PhD<br />

Michael Torres, MD<br />

Tiffany A. Traina, MD<br />

Claude Tremblay, MD<br />

Nicholas Triantafillou, MD<br />

Theodore J. Trumble II, MD<br />

Tien-Tsai Tsai, BM<br />

Calogero Tumminello, MD<br />

Robert M. Tuttle, MD<br />

Theodore I. Tyberg, MD, MSc<br />

Sudhir P. Vaidya, MBBS, MS<br />

Miguel Valderrabano, MD<br />

Emmanuel Valery, MD<br />

Marcel Rudolf M. van den Brink,<br />

MD, PhD<br />

Nicholas Jon Vander Els, MD<br />

Nitza A. Vanga, MD<br />

Lisa Catherine Vasanth (Varley), MD<br />

Stephen R. Veach, MD<br />

Saimamba Veeramachaneni, MBBS<br />

Sindhaghatta K. Venkatram, MBBS<br />

Vasundhara Vidyarthi, MBBS<br />

Adrienne Vincenzino, MD<br />

Annette M. Visconti, MD<br />

Thomas T. Vo, MD, MBA<br />

Nicholas G. Vogiatzis, MD<br />

Rachel Waldron, MD<br />

Lila A. Wallis, MD<br />

Mary Beth Walsh, MD<br />

Frederick A. Walther, MD<br />

Rimda Wanchoo, MBBS<br />

John C.L. Wang, MD, PhD<br />

Craig Warschauer, MD<br />

Carolyn Wasserheit-Lieblich, MD<br />

Muhammad Wattoo, MBBS<br />

Ge<strong>of</strong>frey Webber, MD<br />

Arnold L. Weg, MD<br />

Wehbeh A. Wehbeh, MD<br />

Clinton G. Weiman, MD<br />

Jeremy A. Weingarten, MD<br />

Howard Weinstein, MD<br />

Jessica M. Weiser-McCarthy, MD<br />

Stephen R. Weiss, MD<br />

Gil Weitzman, MD<br />

David Wentzel, DO<br />

Mary H. White, MD<br />

Hendricks H. Whitman, III, MD<br />

Joseph Wiesel, MD<br />

Pamela G. Williams-Russo, MD, MPH<br />

Sidney J. Winawer, MD<br />

William L. Winters, Jr., MD<br />

Ruth L. Wintz, MD<br />

Natasha Withers, DO<br />

Robert E. Wittes, MD<br />

James F. Wittmer, MD<br />

Jedd Wolchok, MD, PhD<br />

David H. Woldenberg, MD<br />

David J. Wolf, MD<br />

Steven Wolinsky, MD<br />

Michael J. Wolk, MD<br />

John Eu-Li Wong, MBBS<br />

Alastair J.J. Wood, MBChB<br />

Anton Wray, MD<br />

Steven Wright, MD<br />

David Lynn Wuest, MD<br />

Kathleen L. Wyne, MD, PhD<br />

Jiaqiong Susan Xu, PhD<br />

Hooman Yaghoobzadeh, MD<br />

Henry Jiann-Cherng Yan, MBBS<br />

Anthony Yang, MD<br />

Christine Yang-Kauh, MD<br />

Mohamed Abdel Daem M. Yassin,<br />

MBBS<br />

Arthur M.F. Yee, MD, PhD<br />

Benson Yeh, MD<br />

Diana A. Yens, MD<br />

Xiaoshuang Nancy Yin, BM<br />

Linus Yoe, MBBS<br />

Bernard Yonk, MD<br />

Serena Yoon, MD<br />

James W. Young, MD<br />

Christine Yu, MD<br />

Florence Yu, MD<br />

Kenneth Ho-ming Yu, MD<br />

Howard S. Yudin, MD<br />

Tasneem Zahra, MBBS<br />

David Zakim, MD<br />

Andrew D. Zelenetz, MD, PhD<br />

Jinghua Zhang, BM<br />

Ming Zhu, MD, MS<br />

Wendy S. Ziecheck, MD<br />

Janice L. Zimmerman, MD<br />

Michael G. Zimmerman, MD<br />

Mahmoud A. Zirie, MBBS<br />

William A. Zoghbi, MD<br />

Research<br />

Highlights<br />

76 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 77


Research Highlights<br />

Christini Lab: Frances Ortega investigates electrophysiological instability<br />

in isolated cardiac myocytes using calcium fluorescence.<br />

Cardiology<br />

Molecular Mechanisms <strong>of</strong> Idiopathic Ventricular Tachycardia<br />

We identified a unique somatic mutation in the adenosine A 1<br />

receptor, originating from a focal right ventricular source that is<br />

responsible for some forms <strong>of</strong> idiopathic right ventricular outflow<br />

tract tachycardia. This arrhythmia is mediated by cAMP-mediated<br />

intracellular calcium overload.<br />

Principal Investigator: B. Lerman, MD<br />

Funding: Sackler Grant<br />

ADAPTIVE CRT Clinical Trial<br />

Multicenter, industry-sponsored trial <strong>of</strong> an investigational algorithm<br />

to optimize cardiac resynchronization therapy by altering RV-LV<br />

pacing timing cycles.<br />

Principal Investigator (<strong>Weill</strong> <strong>Cornell</strong> Site): J. Cheung, MD<br />

Funding: Medtronic<br />

Mechanisms <strong>of</strong> Cardiac Alternans<br />

Cardiac alternans is an electrophysiological instability that can<br />

trigger lethal cardiac arrhythmias. We are using a synergistic<br />

computational and experimental (patch clamping and subcellular<br />

calcium imaging) approach to determine its mechanism. In the past<br />

year we have provided new insight into the critical role that calcium<br />

dynamics play in triggering alternans at the cellular to tissue levels.<br />

Principal Investigator: D. Christini, PhD<br />

Funding: NIH<br />

Predictive Multiscale Modeling <strong>of</strong> a trial Fibrillation for<br />

Therapy Development<br />

We are using multiscale computational modeling, informed<br />

by electrophysiological experiments, to predict the efficacy <strong>of</strong><br />

pharmacological agents in controlling paroxysmal, persistent<br />

and chronic atrial fibrillation in the presence <strong>of</strong> common human<br />

ion-channel polymorphisms.<br />

Principal Investigators: D. Christini, PhD and G. W. Abbott, PhD<br />

Funding: NIH<br />

Genetics <strong>of</strong> Coronary Artery Disease in Alaska Natives,<br />

Phase II<br />

This study enrolled 1,214 western Alaskan Eskimos in extended<br />

families who had carotid ultrasound studies and computerized<br />

ECGs read at <strong>Weill</strong> <strong>Cornell</strong>, and re-evaluated them and additional<br />

key family members in the second phase. Novel analyses have<br />

shown that individual saturated fatty acids are associated with<br />

different components <strong>of</strong> insulin resistance and glucose metabolism,<br />

and that genetic variation in APOJ, LPL and TNFRSF10B genes affect<br />

plasma fatty acid distribution in Alaska Eskimos.<br />

Principal Investigator (<strong>Weill</strong> <strong>Cornell</strong> Subcontract):<br />

R. Devereux, MD<br />

Funding: NHLBI<br />

Cardiovascular Evaluation for the Strong Heart Study, Phase V<br />

This study re-evaluated by echocardiography, carotid ultrasound<br />

and computerized ECGs and performed initial popliteal ultrasound<br />

studies in ~3,200 members <strong>of</strong> 64 multigeneration American Indian<br />

families. Novel results include demonstration <strong>of</strong> closer relations <strong>of</strong><br />

central than brachial arterial pressure to cardiovascular structure<br />

and function; identification <strong>of</strong> association <strong>of</strong> the KIAA1797 gene;<br />

and development <strong>of</strong> methods to take into account relatedness<br />

within extended families in genetic epidemiology studies.<br />

Principal Investigator: R. Devereux, MD<br />

Funding: NHLBI<br />

Genetic Epidemiology <strong>of</strong> Left Ventricular Hypertrophy<br />

This study utilizes data from echocardiograms read at <strong>Weill</strong><br />

<strong>Cornell</strong> to identify genes contributing to abnormalities <strong>of</strong> left<br />

ventricular (LV) structure and function. The most recent discovery<br />

identifies strong genome-wide associations <strong>of</strong> SNPs in the NCAM1,<br />

ADAMTS14 and KIF6 genes for adverse LV phenotypes in 1,258<br />

African-American HyperGEN participants that were replicated<br />

in 989 hypertensive participants in the GENOA study whose<br />

echocardiograms had also been read at <strong>Weill</strong> <strong>Cornell</strong>.<br />

Principal Investigator (<strong>Weill</strong> <strong>Cornell</strong> Subcontract):<br />

R. Devereux, MD<br />

Funding: NHLBI<br />

Randomized Clinical Trial <strong>of</strong> Beta Blocker Therapy (Atenolol)<br />

vs. Angiotensin II Receptor Blocker Therapy (Losartan) in<br />

Individuals with Marfan Syndrome<br />

This study has enrolled all <strong>of</strong> the targeted 604 participants.<br />

Follow-up <strong>of</strong> participants has exceeded expectations and the<br />

independent Data and Safety Monitoring Board has recommended<br />

study continuation after an interim review.<br />

Principal Investigator (<strong>Weill</strong> <strong>Cornell</strong> Subcontract):<br />

M. Roman, MD<br />

Funding: NHLBI; National Marfan Foundation<br />

Genetically Associated Thoracic Aortic Aneurysm (GENTAC)<br />

Registry<br />

This multicenter registry is obtaining biological samples and<br />

longitudinal data from individuals with inherited aortic disease<br />

so as to identify biologic, imaging and clinical predictors <strong>of</strong> aortic<br />

aneurysm progression. The registry has enrolled over 2,200 patients,<br />

with <strong>Weill</strong> <strong>Cornell</strong> contributing the largest number <strong>of</strong> participants.<br />

New findings include delineation <strong>of</strong> a role <strong>of</strong> aortic annular<br />

dilatation in causing aortic regurgitation, clarification <strong>of</strong> systematic<br />

differences among methods <strong>of</strong> measuring aortic size and estimation<br />

<strong>of</strong> rates <strong>of</strong> dissection/surgery in the distal aorta after aortic root<br />

replacement.<br />

Principal Investigator (<strong>Weill</strong> <strong>Cornell</strong> Site): R. Devereux, MD<br />

Co-Investigators : M. Roman, MD, J. Weinsaft, MD<br />

Funding: NHLBI<br />

78 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 79


Research Highlights continued<br />

Near-term Downstream Outcomes <strong>of</strong> CCTA vs. Myocardial<br />

Perfusion SPECT (MPS) for Initial Diagnosis <strong>of</strong> Stable<br />

Chest Pain<br />

The downstream outcomes <strong>of</strong> CCTA versus MPS have not been<br />

directly compared. We performed a randomized, controlled pilot<br />

study <strong>of</strong> CCTA versus MPS for near-term resource utilization,<br />

quality <strong>of</strong> life, cost, and radiation exposure.<br />

Principal Investigator: J. Min, MD<br />

Funding: Tennessee Heart and Vascular Institute (subcontract)<br />

Presentation, Treatment and Outcomes <strong>of</strong> Early, Late and<br />

Very Late Stent Thrombosis: A Report from the American<br />

College <strong>of</strong> Cardiology National Cardiovascular Data Registry<br />

The goal <strong>of</strong> this study is to examine the current frequency,<br />

presenting clinical symptoms, current therapy and in-hospital<br />

outcomes in patients presenting with angiographically documented<br />

stent thrombosis in the American College <strong>of</strong> Cardiology National<br />

Cardiovascular Data Registry.<br />

Principal Investigators: D. Feldman, MD, E. Armstrong, MD<br />

(Boston)<br />

Funding: American College <strong>of</strong> Cardiology<br />

TAO (Treatment <strong>of</strong> Acute Coronary Syndrome with<br />

Otamixaban) Trial<br />

Investigation <strong>of</strong> a novel anti-Xa inhibitor (Otamixaban) in patients<br />

with acute coronary syndromes. Multicenter, randomized, doubleblind<br />

trial <strong>of</strong> otamixaban versus unfractionated heparin plus<br />

eptifibatide in patients with moderate-to-high-risk non-ST elevation<br />

acute coronary syndromes with a planned early invasive strategy.<br />

Principal Investigator: D. Feldman, MD<br />

Funding: San<strong>of</strong>i Aventis<br />

TBX5 and Histone Deacetylases in Cardiogenesis<br />

Congenital heart malformations are the most common birth<br />

defects. Mutations in the gene encoding the TBX5 transcription<br />

factor are causative for congenital cardiac septation and<br />

conduction system defects. We have identified a novel TBX5<br />

downstream target gene, HDAC2, that may be responsible<br />

for mediating some <strong>of</strong> the deleterious effects caused by TBX5<br />

haploinsufficiency during abnormal cardiac development. We seek<br />

to identify the mechanisms by which TBX5 influences HDAC2<br />

expression and activity in order to regulate cardiogenesis.<br />

Principal Investigator: C. Hatcher, PhD<br />

Funding: NIH<br />

Let-7 miRNA in Cardiac Development<br />

MicroRNAs are novel post-transcriptional regulatory elements that<br />

provide precise and subtle regulation <strong>of</strong> target genes, including<br />

transcription factors. We have identified a novel microRNA circuit<br />

that controls heart development and relates to congenital heart<br />

disease. Through experimental models, we will identify interactions<br />

between the let-7 microRNA and the TBX5 transcription factor<br />

to determine how this microRNA pathway regulates heart<br />

development.<br />

Principal Investigator: C. Hatcher, PhD<br />

Funding: NIH<br />

ATHENA-1: A Randomized, Multicenter Study <strong>of</strong><br />

Ambrisentan and Sildenafil Combination Therapy in<br />

Subjects with Pulmonary Arterial Hypertension Who Have<br />

Demonstrated a Suboptimal Response to Sildenafil<br />

This Phase 4, open-label study will evaluate the efficacy and safety<br />

<strong>of</strong> ambrisentan/PDE-5i combination therapy in patients with<br />

pulmonary arterial hypertension (PAH) who have demonstrated<br />

a suboptimal response to PDE-5i therapy alone.<br />

Principal Investigator: E. Horn, MD<br />

Funding: Gilead Sciences<br />

Rapid Switch from Intravenous Epoprostenol to Intravenous<br />

Remodulin ® (Treprostinil Sodium) Using the Crono Five<br />

Ambulatory Infusion Pump in Patients with Stable Pulmonary<br />

Arterial Hypertension: Safety, Efficacy and Treatment<br />

Satisfaction<br />

Pulmonary arterial hypertension (PAH), which is defined as an<br />

elevation in pulmonary arterial pressure and pulmonary vascular<br />

resistance, is a severe hemodynamic abnormality common to a<br />

variety <strong>of</strong> diseases and syndromes. Elevation <strong>of</strong> pulmonary arterial<br />

pressure causes an increase in right ventricular tension during heart<br />

contraction, impairing right ventricular function and ultimately<br />

leading to inactivity and death. The goal <strong>of</strong> PAH treatment is to<br />

lengthen survival time, ameliorate symptoms <strong>of</strong> PAH and improve<br />

health-related quality <strong>of</strong> life.The effects <strong>of</strong> switching from intravenous<br />

Flolan to intravenous Remodulin therapy will be compared. This<br />

eight-week study will also assess the effect that changing to<br />

Remodulin has on treatment satisfaction and patient quality <strong>of</strong> life.<br />

Principal Investigator: E. Horn, MD<br />

Funding: United Therapeutics<br />

Interagency Registry <strong>of</strong> Mechanically Assisted Circulatory<br />

Support (INTERMACS)<br />

Mechanical circulatory support devices (MCSDs) have been<br />

developed to augment or supplant failing myocardial performance.<br />

This therapy has been used most recently as permanent<br />

implantation or “destination therapy” for intractable heart failure.<br />

INTERMACS is an observational registry <strong>of</strong> patients with end-stage<br />

heart failure who receive an FDA-approved MCSD.<br />

Principal Investigator: E. Horn, MD<br />

Funding: NHLBI<br />

Lipoprotein-Associated Phospholipase A2, Myeloperoxidase<br />

and Risk <strong>of</strong> Cardiovascular Disease in American Indians: The<br />

Strong Heart Study<br />

This ancillary project <strong>of</strong> the Strong Heart Study consists <strong>of</strong> a nested<br />

case-control study to examine the role <strong>of</strong> lipoprotein-associated<br />

phospholipase A2 and myeloperoxidase as risk factors for coronary<br />

heart disease and stroke in American Indians.<br />

Principal Investigator: J. Kizer, MD<br />

Funding: DiaDexus<br />

Delayed Enhancement MRI for Detection <strong>of</strong> Sub-Clinical<br />

Papillary Muscle Infarction<br />

The goal <strong>of</strong> this study is to elucidate novel structural mechanisms<br />

and predictive indices <strong>of</strong> post-myocardial infarction mitral<br />

regurgitation (MR), with focus on papillary muscle infarction<br />

detected by DE-MRI tissue characterization as a longitudinal<br />

predictor <strong>of</strong> mitral regurgitation.<br />

Principal Investigator: J. Weinsaft, MD<br />

Funding: NHLBI; NIH<br />

Molecular Genetics <strong>of</strong> Carney Complex<br />

We seek to define the molecular genetic etiologies for human<br />

cardiac myxoma syndromes, including Carney complex. Cardiac<br />

myxomas arise from pluripotent stem cells in the heart, and<br />

deciphering the genetic mechanisms underlying their growth and<br />

differentiation not only fosters new diagnostic and treatment The PARTNER (US) Trial: Placement <strong>of</strong> AoRtic TraNscathetER<br />

strategies, but also suggests new approaches to manipulate stem Valves Trial<br />

cells for a wide variety <strong>of</strong> cardiomyopathies.<br />

Percutaneous aortic valve replacement – 30 patients.<br />

Dr. David Christini discussing the behavior <strong>of</strong> aberrant<br />

Principal Investigator: C. Hatcher, PhD<br />

Principal Investigator: S.C. Wong, MD<br />

electrical waves in a computer simulation <strong>of</strong> atrial fibrillation<br />

Funding: NIH<br />

Funding: Edwards Lifesciences<br />

80 with <strong>Department</strong> a collaborator, <strong>of</strong> <strong>Medicine</strong> Dr. Trine Krogh-Madsen. Annual Report 2011 81


Research Highlights continued<br />

Gauging Responsiveness with A VerifyNow assay – Impact<br />

on Thrombosis And Safety (GRAVITAS)<br />

Effects <strong>of</strong> single versus double dose <strong>of</strong> Plavix on patients post PCI<br />

(54 patients).<br />

Principal Investigator: R. Minutello, MD<br />

Funding: Accumetrics<br />

Closure <strong>of</strong> Atrial Septal Defects with the Amplatzer Septal<br />

Occluder Post-approval Study<br />

Evaluation <strong>of</strong> hemodynamic post closure <strong>of</strong> ASD with Amplatzer<br />

device (20 patients).<br />

Principal Investigator: G. Bergman, MBBS<br />

Funding: AGA Medical Corporation<br />

A Study <strong>of</strong> the Evalve Cardiovascular Valve Repair System<br />

(CVRS) Endovascular Valve Edge-to-Edge REpair Study II<br />

(EVEREST II) Protocol # 401 Continued Access Registry<br />

Reducing MR with a Clip (four patients).<br />

Principal Investigator: S.C. Wong, MD<br />

Funding: Abbott Vascular<br />

Clinical Epidemiology and Evaluative Sciences<br />

Research<br />

Center <strong>of</strong> Excellence in Disparities Research and Community<br />

Engagement<br />

The Center for Excellence in Health Disparities Research and<br />

Community Engagement (CEDREC) currently has over $8 million<br />

in funding from the NIH, and involves <strong>Weill</strong> <strong>Cornell</strong> Medical<br />

College, Hunter College School <strong>of</strong> Nursing, Lincoln Medical Center/<br />

Renaissance Health System and NYU Medical Center – Center for<br />

Healthful Behavior Change. Faculty from the <strong>Department</strong> <strong>of</strong> Public<br />

Health at <strong>Weill</strong> <strong>Cornell</strong> who are also collaborating on CEDREC<br />

include: Dr. Alvin Mushlin, Dr. Heejung Bang, and Dr. Linda Gerber.<br />

The specific aims <strong>of</strong> CEDREC are: to create an interdisciplinary<br />

academic and community research enterprise that will expand<br />

the capacity for conducting cutting-edge and transdisciplinary<br />

research and contribute to improving minority health and reducing<br />

health disparities in cardiovascular disease and cancer in Central<br />

Harlem and the South Bronx; to train new minority investigators<br />

to conduct original minority health and health disparities research<br />

and foster their ability to obtain independent NIH funding; to build<br />

upon existing community-academic partnerships and forge new<br />

collaborations that will accelerate the dissemination <strong>of</strong> research<br />

findings to community stakeholders, inform novel communitybased<br />

programs and build their capacity for research.<br />

Principal Investigator: C. Boutin-Foster, MD, MS<br />

Co-Principal Investigator: M. E. Charlson, MD<br />

Funding: NIH/NCMHD (2009–14)<br />

Minority Investigator Research Supplement to SCALE: Small<br />

Changes and Lasting Effects<br />

Body image discrepancy and risk knowledge about obesity are key<br />

constructs that will enhance our understanding and prediction<br />

<strong>of</strong> who will fare well with a small change approach to weight<br />

loss. We will also explore the relationship <strong>of</strong> the body size <strong>of</strong> the<br />

social network and the social network health impact <strong>of</strong> obesity/<br />

overweight in relation to success in weight loss.<br />

Principal Investigator: M. E. Charlson, MD<br />

Recipient: G. Winston, MD<br />

Funding: NIH/NHLBI (2010–14)<br />

Post-Master’s Degree Research Supplement to SCALE: Small<br />

Changes and Lasting Effects<br />

This project is largely embedded in the parent grant, SCALE: Small<br />

Changes and Lasting Effects. The classification <strong>of</strong> programs in<br />

faith-based settings is a logical extension <strong>of</strong> the parent grant that<br />

evaluates environmental influences that may be impacting the<br />

uptake <strong>of</strong> mindful eating intervention.<br />

Principal Investigator: M. E. Charlson, MD<br />

Recipient: J. Hippolyte, MPH<br />

Funding: NIH/NHLBI (2010–11)<br />

SCALE: Small Changes and Lasting Effects<br />

Part <strong>of</strong> the NIH-funded Center for Behavioral Research in Obesity,<br />

SCALE is a partnership between the <strong>Department</strong>s <strong>of</strong> Sociology,<br />

Behavioral Psychology, Nutrition and Statistics at <strong>Cornell</strong> University<br />

in Ithaca and Lincoln Medical Center/Renaissance Health System in<br />

the Bronx. It builds upon the work <strong>of</strong> Drs. Boutin-Foster and Phillips-<br />

Caesar, who are co-investigators on the project, as well as on<br />

the work <strong>of</strong> Drs. Devine, Wansink, Wethington and Wells. This<br />

multimillion dollar grant focuses on developing individual, family and<br />

faith-based mindful eating interventions targeted at reducing obesity<br />

in minority communities. The project is designed to develop and<br />

test different multilevel interventions in pro<strong>of</strong>-<strong>of</strong>-concept trials to lay<br />

the basis for evaluating its effectiveness in large-scale clinical trials.<br />

SCALE now has two minority supplements that were successfully<br />

awarded in 2010.<br />

Principal Investigator: M. E. Charlson, MD<br />

Funding: NIH/NHLBI (2009–14)<br />

Autoregulation and Systemic Blood Pressure: A New View<br />

<strong>of</strong> Normal Tension Glaucoma<br />

This study aims to determine whether a larger prospective<br />

cohort study should be undertaken, and to help define optimal<br />

monitoring strategies for patients with normal tension glaucoma.<br />

Now in the final year <strong>of</strong> the study, the division is in the process <strong>of</strong><br />

completing the follow-up data.<br />

Principal Investigator: M. E. Charlson, MD<br />

Funding: NEI (2008–11)<br />

Clinical Pharmacology<br />

New Drug to Activate Peripheral Histamine 3 Receptors<br />

Activating the histamine 3 receptor lowers the epinephrine in the<br />

ischemic heart and should reduce arrhythmias. A series <strong>of</strong> novel<br />

compounds are being made and screened to find a drug that will<br />

reduce arrhythmias in ischemic hearts.<br />

Principal Investigator: M. M. Reidenberg, MD<br />

Funding: NIH<br />

Emergency <strong>Medicine</strong><br />

Neurological Emergencies Treatment Trials (NETT)<br />

A five-year grant to create a network <strong>of</strong> tertiary care emergency<br />

departments capable <strong>of</strong> conducting research in neurological<br />

emergency care. This year the first two trials were initiated: Rapid<br />

Anticonvulsant Medication Prior to Arrival Trial (RAMPART) and<br />

Albumin in Acute Stroke (ALIAS).<br />

Principal Investigators: N. Flomenbaum, MD, and<br />

M. Fink, MD (site)<br />

Funding: NIH/ NINDS<br />

An International Multicenter Study to Evaluate a Six-Hour<br />

Observation Period for Cocaine-Associated Chest Pain<br />

A two-year grant to determine if six hours <strong>of</strong> observation<br />

combined with a six-hour troponin and ECG is an adequate<br />

length <strong>of</strong> time to determine which patients are at risk for serious<br />

complications <strong>of</strong> cocaine-associated chest pain.<br />

Principal Investigator: J. Prosser, MD<br />

Funding: American Academy <strong>of</strong> Clinical Toxicology<br />

Endocrinology, Diabetes and Metabolism<br />

American Recovery and Reinvestment Act Administrative<br />

Supplements for Comparative Effectiveness Research<br />

Workforce Development<br />

This supplement has two objectives: to strengthen current formal<br />

educational opportunities in CER by increasing the scope and<br />

<strong>of</strong>ferings in the track in outcomes and health services research;<br />

to <strong>of</strong>fer an additional year <strong>of</strong> training in CER as a KL2 scholar<br />

to students who are enrolled in, or who have obtained, either a<br />

master’s degree or certificate in clinical and translational research.<br />

These trainees will work with faculty who are developing these<br />

courses and will engage in tutorials, selective electives and<br />

personalized learning experiences. They will pursue a year <strong>of</strong><br />

mentored research with faculty in the area <strong>of</strong> CER.<br />

Principal Investigator: J. L. Imperato-McGinley, MD<br />

Co-Principal Investigator: A. Mushlin, MD<br />

Funding: NIH<br />

DEFEND‐2: Durable-response Therapy Evaluation for Earlyor<br />

New-onset Type 1 Diabetes<br />

A randomized, placebo-controlled, double-blind, international<br />

study <strong>of</strong> the efficacy and safety <strong>of</strong> otelixizumab in adolescents<br />

and adults with new-onset type 1 diabetes mellitus.<br />

Principal Investigator: H. Karakelides, MD<br />

Funding: Tolerx<br />

NIH T32 Training Grant<br />

The Endocrine Research Training Program at <strong>Weill</strong> <strong>Cornell</strong> is<br />

a Tri-Institutional endeavor with participation from Memorial<br />

Sloan-Kettering Cancer Center and The Rockefeller University.<br />

The overarching goal <strong>of</strong> this program is to provide multidisciplinary<br />

translational endocrine research training to postdoctoral trainees<br />

to prepare them for independent careers in biomedical research.<br />

The program has two tracks: a laboratory/preclinical track and<br />

a clinical research track.<br />

Principal Investigator: J. L. Imperato-McGinley, MD<br />

Funding: NIH<br />

Epidemiology <strong>of</strong> Diabetes Intervention and Complications<br />

(EDIC) Trial<br />

The EDIC trial is a continuation study involving the Diabetes<br />

Control and Complications Trial (DCCT) cohort. The EDIC study<br />

has now followed nearly 1,400 individuals with type 1 diabetes for<br />

over 30 years.<br />

Principal Investigator: D. Brillon, MD<br />

Funding: NIH/NIDDK<br />

Action to Control Cardiovascular Risk in Diabetes<br />

(ACCORD) Study<br />

The ACCORD trial compares intensive blood glucose, lipid<br />

and blood pressure control in over 10,000 persons with<br />

type 2 diabetes.<br />

Principal Investigator: D. Brillon, MD<br />

Funding: NIH/NHLBI<br />

A Randomized, Placebo-controlled, Double-blind<br />

Investigation <strong>of</strong> the Effects <strong>of</strong> Potassium Citrate on Bone<br />

Metabolism in Postmenopausal Osteopenia<br />

To determine the effects <strong>of</strong> administration <strong>of</strong> an alkaline<br />

compound, potassium citrate, on bone turnover and bone<br />

mineral density.<br />

Principal Investigator: N. Sinha, MD<br />

Funding: CTSC and Acidosis Research Fund<br />

Sex Steroids and Cardiovascular Disease Risk<br />

To study the effects <strong>of</strong> sex steroids on cardiovascular disease by<br />

examining surrogate markers <strong>of</strong> cardiovascular disease in patients<br />

with complete androgen insensitivity and 5α-reductase-2 deficiency,<br />

and comparing these to normal controls.<br />

Principal Investigator: J. L. Imperato-McGinley, MD<br />

Funding: NIH<br />

Androgen Regulation <strong>of</strong> Endothelial Progenitor Cells and<br />

Endothelial Cells<br />

The major goal <strong>of</strong> this project is to study the effects and<br />

mechanisms <strong>of</strong> androgens on the regulation <strong>of</strong> endothelial<br />

progenitor cells and endothelial cells using human and animal<br />

models with defects in androgen actions as well as in vitro cell<br />

cultures.<br />

Principal Investigator: Y.S. Zhu, MD, PhD<br />

Funding: CTSC/NIH<br />

Dual Action <strong>of</strong> NSC606985 on LAPC-4 Prostatic Tumor Cell<br />

Growth is Mediated via PKCd<br />

NSC606985 is a potential chemotherapeutic agent for prostate<br />

cancer. However, in LAPC-4 cells, NSC606985 produces a dual<br />

action on cell growth. The investigators have revealed that this<br />

dual action is mediated via PKCd, mainly due to the differential<br />

activation <strong>of</strong> PKCd in different cell compartments.<br />

Principal Investigators: Y.S. Zhu, MD, PhD and<br />

J. L. Imperato-McGinley, MD<br />

Funding: Cohen Fund<br />

Dietary Fat on the Regulation <strong>of</strong> Prostate Grp78 Expression<br />

and Prostate Tumorigenesis in the Rat<br />

A continuing exploration <strong>of</strong> dietary effect on the regulation <strong>of</strong><br />

prostate gene expression. The team has demonstrated that a high<br />

dietary fat intake increases prostate tumorigenesis and prostate<br />

Grp78 level without a significant alteration in Grp78 mRNA<br />

concentration.<br />

Principal Investigator: Y.S. Zhu, MD, PhD<br />

Funding: United Soybean Board<br />

Genotype-Phenotype Analysis <strong>of</strong> CAH in the Dominican<br />

Population<br />

A continuing effort to elucidate the genotype-phenotype<br />

relationship <strong>of</strong> CAH in the Dominican population. The team has<br />

identified various mutations in the 21-hydrolase (CYP21) gene, and<br />

a specific mutation is identified in the Dominican population.<br />

Principal Investigators: J. L. Imperato-McGinley, MD and<br />

Y.S. Zhu, MD, PhD<br />

Funding: Argenbright Research Fund<br />

82 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 83


Research Highlights continued<br />

Gastroenterology and Hepatology<br />

A Randomized, Parallel Group, Dose-ranging Study to<br />

Evaluate Efficacy, Safety, Pharmacokinetics and Antiviral<br />

Activity <strong>of</strong> VX 222 and Telaprevir in Combination with<br />

and without Peginterferon Alfa 2a (Pegasys) and Ribavirin<br />

(Copegus) in Treatment-naïve Subjects with Genotype 1<br />

Chronic Hepatitis C<br />

The primary objective <strong>of</strong> this study is to assess the safety and<br />

tolerability <strong>of</strong> combination treatment with VX-222 and telaprevir<br />

administered for 12 weeks with and without pegylated interferon<br />

alfa-2a and ribavirin.<br />

Principal Investigator: I. M. Jacobson, MD<br />

Funding: Vertex Pharmaceuticals<br />

A Randomized, Open-label, Multicenter, Dose and Duration<br />

Finding Study to Evaluate the Sustained Virologic Response<br />

<strong>of</strong> the HCV Protease Inhibitor Danoprevir Boosted with Low<br />

Dose Ritonavir (danoprevir/r) in Combination with Pegasys<br />

and Copegus vs. Pegasys and Copegus Alone in Treatment-<br />

Naïve Patients with Chronic Hepatitis C Genotype 1 or 4<br />

Virus Infection. NV22776<br />

The primary objective <strong>of</strong> this trial is to study the different doses<br />

and durations <strong>of</strong> danoprevir ritonovir treatment combination with<br />

Pegasys and Copegus on the proportion <strong>of</strong> patients who achieve<br />

sustained virological response versus the currently approved<br />

combination <strong>of</strong> Pegasys and Copegus in treatment-naïve patients<br />

with chronic hepatitis C genotype 1 or 4 virus infection.<br />

Principal Investigator: I. M. Jacobson, MD<br />

Funding: Roche/Genitech<br />

TMC435-TiDP16-C206(ASPIRE)<br />

A Phase IIb, randomized, double-blind, placebo-controlled trial to<br />

investigate the efficacy, tolerability, safety and pharmacokinetics<br />

<strong>of</strong> TMC435 as part <strong>of</strong> a treatment regimen including PegIFN -2a<br />

and ribavirin in HCV genotype 1 infected subjects who failed to<br />

respond or relapsed following at least one course <strong>of</strong> PegIFN -2a/b<br />

and RBV therapy.<br />

Principal Investigator: I. M. Jacobson, MD<br />

Funding: Johnson and Johnson<br />

Identification <strong>of</strong> Early Biomarkers/Targets for Cancer<br />

Prevention Using Metabolomic Screening<br />

The goal <strong>of</strong> this project is to identify molecular biomarkers/<br />

targets for cancer prevention using metabolomic pr<strong>of</strong>iling in<br />

morphologically normal and neoplastic tissues. The impact <strong>of</strong> a<br />

tumor-suppressor gene on the metabolic pr<strong>of</strong>ile will be defined.<br />

Principal Investigator: A.J. Dannenberg, MD<br />

Funding: NIH/NCI<br />

Molecular Determinants <strong>of</strong> Intestinal Inflammation<br />

This project seeks to elucidate the mechanisms that control<br />

mucosal homeostasis with the goal <strong>of</strong> developing new strategies to<br />

prevent or treat inflammatory bowel disease.<br />

Principal Investigator: A.J. Dannenberg, MD<br />

Funding: New York Crohn’s Foundation<br />

Mechanisms <strong>of</strong> Notch Signaling in Colon Cancer Initiating Cells<br />

This project studies the role <strong>of</strong> the NOTCH signaling pathway in<br />

colon cancer initiating cells and the potential roles <strong>of</strong> NOTCH<br />

inhibition in colon cancer chemoprevention and combination<br />

chemotherapy.<br />

Principal Investigator: S. Lipkin, MD, PhD<br />

Funding: NIH<br />

Metabolomic Biomarkers <strong>of</strong> DFMO and Sulindac in Colon<br />

Adenoma Prevention<br />

This project uses metabolomics to identify novel metabolic<br />

biomarkers and potential dietary questions to be incorporated into<br />

the SWOG S0820 phase III trial <strong>of</strong> DFMO/Sulindac in the prevention<br />

<strong>of</strong> secondary colorectal adenomas and cancers.<br />

Principal Investigator: S. Lipkin, MD, PhD<br />

Funding: NIH<br />

Pharmacogenetics <strong>of</strong> HMGCR in Colon and Prostate Cancer<br />

Chemoprevention<br />

This project studies the role <strong>of</strong> HMGCR genetic variants affecting<br />

alternative splicing in modulating efficacy <strong>of</strong> statin drugs in colon<br />

and prostate cancer risk reduction.<br />

Principal Investigator: S. Lipkin, MD, PhD<br />

Funding: NIH<br />

A Multicenter, Placebo-controlled, Dose-ranging Study to<br />

Investigate the Safety, Tolerability, Pharmacokinetics and<br />

Pharmacodynamics Following Oral Administration <strong>of</strong> PSI-<br />

7977 in Combination with Pegylated Interferon and Ribavirin<br />

in Treatment-naïve Patients with Chronic HCV Infection<br />

Genotype 1, and an Open-label Assessment <strong>of</strong> PSI-7977 in<br />

Patients with HCV Genotype 2 or 3 (Pharmasset P7977-0422)<br />

The primary objective <strong>of</strong> this study is to assess the safety and<br />

tolerability <strong>of</strong> PSI-7977 for 12 weeks, administered in combination<br />

with standard-<strong>of</strong>-care in treatment-naïve patients with HCV<br />

genotype 1, 2 or 3.<br />

Principal Investigator: I. M. Jacobson, MD<br />

Funding: Pharmasset<br />

Boceprevir and Peginterferon/Ribavirin for the Treatment<br />

<strong>of</strong> Chronic Hepatitis C in Treatment-naïve Subjects: A<br />

Comparison <strong>of</strong> Erythropoietin Use vs. Ribavirin Dose<br />

Reduction for the Management <strong>of</strong> Anemia<br />

The primary objective <strong>of</strong> this trial is to compare the effect on<br />

efficacy <strong>of</strong> erythropoietin use versus ribavirin dose reduction for the<br />

management <strong>of</strong> anemia in subjects who become anemic during<br />

the treatment <strong>of</strong> chronic hepatitis C genotype 1 infection with<br />

boceprevir plus peginterferon alfa-2b and ribavirin therapy.<br />

Principal Investigator: I. M. Jacobson, MD<br />

Funding: Merck and Company<br />

Risks Factors for AIDS among IV Drug Users<br />

These studies seek to identify the mechanism by which high-risk<br />

exposed individuals are protected from HIV infection.<br />

Co-Investigator: A. Talal, MD<br />

Funding: NIH/NIDA<br />

Assessment by Meta-analysis <strong>of</strong> Treatment <strong>of</strong> Addiction as a<br />

Determinant <strong>of</strong> Successful Treatment Response for Hepatitis<br />

C Virus Infection in Drug Users<br />

The goal <strong>of</strong> this study is to assess the effect <strong>of</strong> treatment <strong>of</strong><br />

addiction on obtaining a successful treatment outcome to therapy<br />

for hepatitis C, using techniques <strong>of</strong> meta-analysis.<br />

Co-Principal Investigator: A. Talal, MD<br />

Funding: Merck and Company<br />

Association between IL28B Genetic Variation and Sustained<br />

Response to PEG-IFN and RBV in American HIV/HCV Coinfected<br />

Patients<br />

The goal <strong>of</strong> this study is to analyze the association between IL28B<br />

and treatment outcome among HIV/HCV co-infected patients.<br />

Principal Investigator: A. Talal, MD<br />

Funding: Merck and Company<br />

Phase IIA Trial Testing Erlotinib as an Intervention against<br />

Intraductal Pancreas Mucinous Neoplasms<br />

A phase IIA observational single-arm study <strong>of</strong> 100 mg/d <strong>of</strong> erlotinib<br />

in patients with intraductal papillary mucinous neoplasms.<br />

Principal Investigator: F. Schnoll-Sussman, MD<br />

Funding: NIH<br />

Phase Ib Study <strong>of</strong> Polyphenon E in Patients with Barrett’s<br />

Esophagus<br />

A consortium study with MD Anderson Cancer Center and<br />

Columbia University to evaluate green tea extract (polyphenon E)<br />

in the potential prevention <strong>of</strong> progression to esophageal cancer in<br />

patients with Barrett’s esophagus.<br />

Principal Investigator: F. Schnoll-Sussman, MD<br />

Funding: NCI<br />

Familial Pancreatic Cancer Family Registry<br />

Evaluation <strong>of</strong> MRCP and EUS procedures as screening tools in<br />

the early detection <strong>of</strong> pancreatic cancer in people with a family<br />

history <strong>of</strong> this disease, along with collection and analysis <strong>of</strong> DNA<br />

from patients with pancreatic cancer and their families to identify<br />

potentially inherited genetic mutations that may contribute to the<br />

development <strong>of</strong> pancreatic cancer.<br />

Principal Investigator: F. Schnoll-Sussman, MD<br />

Funding: Partial funding from Hayes Foundation and Helen<br />

Kaufman Memorial Fund<br />

Study <strong>of</strong> Biomarkers <strong>of</strong> Colorectal Cancer<br />

Analysis <strong>of</strong> novel biomarkers in the blood <strong>of</strong> people diagnosed<br />

with colorectal cancer, which could contribute to the development<br />

<strong>of</strong> improved and/or less invasive colon cancer screening.<br />

Principal Investigator: F. Schnoll-Sussman, MD<br />

Funding: GeneNews<br />

The Changing Epidemiology <strong>of</strong> Clostridium difficile Infection<br />

in Inflammatory Bowel Disease Patients<br />

The purpose <strong>of</strong> this study is to identify the risk factors and<br />

incidence for C. difficile infection and its severity in the IBD<br />

population.<br />

Principal Investigator: C. Crawford, MD<br />

Funding: Rudin Foundation<br />

Clostridium difficile Infections in Patients with Hematologic<br />

Malignancies<br />

The purpose <strong>of</strong> this study is to identify and evaluate the risk factors<br />

for C. difficile infection in patients with hematologic malignancies<br />

before, during and after their treatment.<br />

Principal Investigator: C. Crawford, MD<br />

Funding: Rudin Foundation<br />

84 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 85


Research Highlights continued<br />

Geriatrics and Gerontology<br />

Edward R. Roybal Center for Research on Applied<br />

Gerontology<br />

This grant created the <strong>Cornell</strong>-Columbia Translational Research<br />

Institute on Pain in Later Life (TRIPLL), a multi-institutional and<br />

interdisciplinary collaboration focused on implementing innovative<br />

strategies for improving pain management among older adults.<br />

Principal Investigator: M. Carrington Reid, MD<br />

Funding: NIH<br />

New York City Elder Abuse Center<br />

The New York City Elder Abuse Center is using a collaborative<br />

approach to establish a much-needed multidisciplinary team (MDT)<br />

<strong>of</strong> experts to coordinate care and create solutions for the growing<br />

number <strong>of</strong> complex cases <strong>of</strong> elder abuse in NYC. The first MDT will<br />

begin work in Brooklyn and, if successful, MDTs will be instituted<br />

in other boroughs, starting next with Manhattan. As it matures<br />

and grows, the center will also serve a larger role as a training<br />

ground and central resource for technical assistance, innovative<br />

best practices, multidisciplinary training, research and policy<br />

development in NYC.<br />

Principal Investigators: M. S. Lachs, MD, MPH and<br />

R. Breckman, LCSW<br />

Funding: The Fan Fox and Leslie R. Samuels Foundation<br />

Resident-to-resident Elder Mistreatment in Long-term Care<br />

Resident-to-resident elder mistreatment (RREM) in nursing homes<br />

remains unstudied despite staff beliefs that aggressive verbal and<br />

physical interactions between residents is common. The aims <strong>of</strong><br />

this research are to develop and refine a case-finding method for<br />

identifying episodes <strong>of</strong> RREM, determine the extent and nature <strong>of</strong><br />

RREM in a sample <strong>of</strong> six nursing homes in NYC, and to conduct an<br />

observational cohort study comparing longitudinal rates <strong>of</strong> diverse<br />

outcomes.<br />

Principal Investigator: M. S. Lachs, MD, MPH<br />

Funding: NIH<br />

Hartford Center <strong>of</strong> Excellence in Geriatric <strong>Medicine</strong><br />

The overarching goal <strong>of</strong> the Hartford Center <strong>of</strong> Excellence (initially<br />

funded in 2005) is to attract and train future academic leaders in<br />

geriatric medicine.<br />

Principal Investigator: M. Carrington Reid, MD<br />

Funding: The John A. Hartford Foundation<br />

Advancing the Quality <strong>of</strong> Palliative Care through Clinician<br />

Education<br />

The goal <strong>of</strong> this work is to develop, implement and seek ways<br />

to sustain a palliative care educational program at the NewYork-<br />

Presbyterian Hospital/<strong>Weill</strong> <strong>Cornell</strong> Medical Center that will<br />

establish a campus-wide educational initiative to complement and<br />

enhance the provision <strong>of</strong> palliative care services.<br />

Principal Investigators: R. D. Adelman, MD, E. Siegler, MD<br />

Funding: Altman Foundation<br />

Hematology/Medical Oncology<br />

Targeted Inhibition <strong>of</strong> BCL6 for Leukemia Stem Cell<br />

Eradication<br />

This project tests the spectrum <strong>of</strong> lymphomas responsive to RI-BPI,<br />

translated RI-BPI for use in clinical trials.<br />

Principal Investigator: A. Melnick, MD<br />

Funding: NIH/NCI<br />

Radiolabeled Anti-PSMA Monoclonal Antibody to Target<br />

Nonprostate Solid Tumor Neovasculature<br />

We propose to use In-J591 to initially identify sites <strong>of</strong> PSMApositive<br />

metastatic disease in subjects with nonprostate cancer.<br />

It is hypothesized that an infusion <strong>of</strong> Lu-J591 will function as an<br />

anti-neovasculature agent to change tumor blood flow, which may<br />

result in regression <strong>of</strong> tumor growth.<br />

Principal Investigator: S. Tagawa, MD<br />

Funding: Pardee Foundation<br />

Targeting <strong>of</strong> Human Acute Myelogenous Leukemia<br />

Stem Cells<br />

This project aims to define putative anti-LSC-specific compounds<br />

with the potential for clinical translation from known FDAapproved<br />

drugs.<br />

Principal Investigator: M. Guzman, PhD<br />

Funding: Lauri Strauss Leukemia Foundation<br />

The Molecular Basis <strong>of</strong> Neuroendocrine Prostate Cancer<br />

The broad objectives <strong>of</strong> this proposal are to discover the genetic<br />

alterations found in NEPC, identify therapeutically targetable<br />

somatic mutations and develop new treatment strategies for<br />

patients with NEPC.<br />

Principal Investigator: H. Beltran, MD<br />

Funding: Prostate Cancer Foundation<br />

Receptor-mediated Control <strong>of</strong> Cell Differentiation<br />

To identify signal transduction pathways downstream <strong>of</strong> proNGF,<br />

to evaluate the role <strong>of</strong> sortilin ectodomain shedding in modulating<br />

proNGF function and to generate and evaluate mice overexpressing<br />

proNGF or proBDNF.<br />

Principal Investigator: B.L. Hempstead, MD, PhD<br />

Funding: NIH/NINDS<br />

Fractionated, Dual-targeted Radioimmunotherapy for<br />

Follicular Lymphoma<br />

This project aims to determine the biodistribution, tumor<br />

localization and pharmacokinetics <strong>of</strong> radiolabeled epratuzumab<br />

therapy, determine any changes in targeting due to pretreatment<br />

with veltuzumab, and establish the safety and efficacy <strong>of</strong><br />

fractionated 90Y-epratuzumab tetraxetan (anti-CD22) given<br />

in combination with veltuzumab (anti-CD20) in patients with<br />

previously untreated, intermediate or high-risk FL.<br />

Principal Investigator: R. Elstrom, MD<br />

Funding: NIH/NCI<br />

Geriatric Mental Health Integration into Primary Practice<br />

This program provides screening and assessment <strong>of</strong> all ambulatory<br />

patients at the Irving Sherwood Wright Center on Aging for<br />

depression and anxiety as well as providing mental health care<br />

for those in need. In conjunction with mental health clinical<br />

services, this program provides an opportunity to develop a unique<br />

database <strong>of</strong> mental health findings in this population, which will<br />

be a rich resource for further research.<br />

Principal Investigator: R. D. Adelman, MD<br />

Funding: New York State Office <strong>of</strong> Mental Health<br />

Characterization <strong>of</strong> Epigenomic Deregulation in Acute<br />

Myeloid Leukemia<br />

A career award project focusing on studies <strong>of</strong> epigenetic<br />

compartments <strong>of</strong> genetic material <strong>of</strong> myeloid leukemia.<br />

Principal Investigator: M. Figueroa, MD<br />

Funding: The Leukemia and Lymphoma Society<br />

Transcriptional Silencing by the BCL6 Oncoprotein<br />

This project aims to determine the mechanism <strong>of</strong> action <strong>of</strong> the<br />

BCL6 transcriptional repressor.<br />

Principal Investigator: A. Melnick, MD<br />

Funding: NIH/NCI<br />

86 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 87


Research Highlights continued<br />

HSP70 as a Novel Target to Specifically Ablate and Detect<br />

AML Stem Cells<br />

This project aims to determine whether HSP70 plays an important<br />

role in LSC maintenance during chemotherapy and therefore<br />

represents a novel target to ablate LSCs without harming HSCs.<br />

Given the cell surface presentation <strong>of</strong> HSP70 and increased HSP70<br />

expression in AML, the investigators may further determine the<br />

potential use <strong>of</strong> HSP70 as a marker to identify chemoresistant LSCs<br />

during minimal residual disease.<br />

Principal Investigator: M. Guzman, PhD<br />

Funding: The Leukemia and Lymphoma Society<br />

A Mouse Model for Human Gastrointestinal Stromal Tumor<br />

This project aims to investigate changes taking place during tumor<br />

development and progression with age in KitV558?/+ mice.<br />

Principal Investigator: J.M. Scandura, MD, PhD<br />

Funding: NIH/NCI (subcontract from MSKCC)<br />

Prostate Cancer Research at <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

This project uses a prototype PSMA-based cell-capture device to<br />

isolate and analyze circulating prostate cancer cells from the blood<br />

<strong>of</strong> patients who are receiving docetaxel and similar chemotherapy.<br />

Additionally, it will investigate the molecular basis <strong>of</strong> the clinical<br />

response <strong>of</strong> prostate cancer patients by assessing androgen<br />

receptor entrapment within the cancer cell and correlating the data<br />

with patients’ clinical progress and seeking drug-resistance-causing<br />

mutations at the site within the cancer cell where docataxel should<br />

be active.<br />

Principal Investigator: D.M. Nanus, MD<br />

Funding: Charles Henry Leach II Foundation<br />

Selection <strong>of</strong> Novel Therapies to Ablate Chemoresistant<br />

Myeloid Leukemia Stem Cell<br />

This project aims to advance the targeting <strong>of</strong> LSCs and reduction <strong>of</strong><br />

relapse by: determining whether ex vivo treatments <strong>of</strong> LSCs more<br />

realistically reflect therapeutic outcome in patients compared to<br />

AML blast populations; defining the gene expression signatures<br />

<strong>of</strong> drug sensitivity and drug resistance <strong>of</strong> LSCs to identify better<br />

therapies; identifying cell lines that best mimic the chemosensitivity<br />

<strong>of</strong> LSCs, to have a readily available LSC surrogate in drug screens.<br />

Principal Investigator: M. Guzman, PhD<br />

Funding: NIH Office <strong>of</strong> the Director<br />

Transcriptional and Epigenetic Characterization <strong>of</strong> the Drug<br />

Resistance in Acute Myelogenous Leukemia Stem Cells<br />

This project aims to understand the epigenetic mechanisms<br />

that lead to LSC chemoresistance to optimize the selection and<br />

identification <strong>of</strong> drugs that can ablate LSCs that drive leukemia<br />

relapse.<br />

Principal Investigator: M. Guzman, PhD<br />

Funding: The V Foundation for Cancer Research<br />

Mechanisms Determining Disease Relapse in Older Patients<br />

with Acute Myeloid Leukemia<br />

This is a collaborative project with Drs. Ross Levine (Memorial<br />

Sloan-Kettering Cancer Center), Christopher Park, Gail Roboz,<br />

Christopher Mason and Monica Guzman. The goal is to determine<br />

the genetic and epigenetic lesions associated with and causative<br />

<strong>of</strong> AML relapse.<br />

Principal Investigator: A. Melnick, MD<br />

Funding: The Starr Foundation<br />

Unraveling the Breast Cancer Metastasis Epigenome<br />

Large-scale characterization <strong>of</strong> the epigenetic landscapes<br />

underlying breast cancer metastasis using a human breast cancer<br />

cell line metastasis model and primary breast tumor samples.<br />

This project will determine the functional significance <strong>of</strong> genes<br />

implicated by this epigenomic analysis.<br />

Principal Investigator: L. Vahdat, MD<br />

Funding: The Starr Foundation (subcontract from Memorial<br />

Sloan-Kettering Cancer Center)<br />

Novel Therapeutics in Lymphoma<br />

This project supports further assessment <strong>of</strong> novel monoclonal<br />

antibodies in B cell malignancies; evaluation <strong>of</strong> combination regimens<br />

with rituximab and biologic agents; studies <strong>of</strong> radioimmunotherapy<br />

as part <strong>of</strong> initial therapy for lymphoma; novel initial therapies for<br />

aggressive lymphoma; new chemotherapy regimens; new efforts in<br />

evaluation <strong>of</strong> lymphoma prognosis and use <strong>of</strong> imaging.<br />

Principal Investigator: J.P. Leonard, MD<br />

Funding: The Lymphoma Foundation<br />

Hospital <strong>Medicine</strong><br />

Systemic Barriers to Quality Pain Management in General<br />

Medical Inpatients<br />

We seek to establish the current state, and to identify system level<br />

barriers, to quality pain management for adult general medical<br />

inpatients with a special focus on the geriatric population, using<br />

a qualitative approach composed <strong>of</strong> patient interviews and<br />

provider focus groups.<br />

Principal Investigator: R. Lin, MD, PhD<br />

Funding: NIH CTSA Planning Award (2010-2011) at WCMC<br />

Clinical and Translational Science Center (CTSC); NIA (National<br />

Institute on Aging) Pilot Grant (2010-2011) at <strong>Cornell</strong>-Columbia<br />

Translational Research Institute on Pain in Later Life (TRIPLL).<br />

Immunology<br />

Strategies to Prevent Death from Influenza Virus Infection<br />

This project is a collaborative project between Imperial College<br />

London and <strong>Weill</strong> <strong>Cornell</strong> Medical College focusing on the<br />

development <strong>of</strong> anti-inflammatory treatments to prevent death<br />

after influenza virus infection (London), and generating<br />

a “T-cell vaccine” for influenza virus (New York).<br />

Principal Investigators: K. A. Smith, MD (New York) and<br />

M. Feldmann, MD (London)<br />

Funding: NIH/NIAID<br />

Developing Novel Therapeutics for CLL<br />

Our previous studies have shown that tumor samples derived<br />

from chronic lymphocytic leukemia (CLL) patients constitutively<br />

express Rel/NF-kB activity, which may provide tumor cell survival<br />

advantage. This project investigates the mechanism underlying CLL<br />

tumorigenesis mediated by the constitutive Rel/NF-kB activity and<br />

develop inhibitors <strong>of</strong> Rel/NF-kB as potential therapy for CLL.<br />

Principal Investigator: H. C. Liou, PhD<br />

Funding: Leukemia & Lymphoma Society<br />

Validation <strong>of</strong> Pyrimidine Trione Compounds as Novel<br />

Therapy for Multiple Myeloma<br />

Recent studies have shown that multiple myeloma expresses high<br />

levels <strong>of</strong> Rel/NF-kB activity which contribute to tumor cell survival<br />

and drug resistance. Our team has identified several Rel/NF-kB<br />

inhibitors. We propose to optimize one class <strong>of</strong> NF-kB inhibitors as<br />

a potential lead compound for multiple myeloma.<br />

Principal Investigator: H. C. Liou, PhD<br />

Funding: Multiple Myeloma Research Foundation<br />

Infectious Diseases<br />

Gut Microbiota and Visceral Adiposity in HIV-Infected<br />

Patients<br />

This study is testing the hypothesis that there are differences in the<br />

bacterial composition <strong>of</strong> the gastrointestinal tracts <strong>of</strong> HIV-infected<br />

patients with excess abdominal fat compared to controls.<br />

Co-Principal Investigators: M. Glesby, MD, PhD and<br />

M. Kamboj, MD (MSKCC)<br />

Funding: <strong>Weill</strong> <strong>Cornell</strong> Clinical and Translational Science Center<br />

HIV/AIDS Clinical Trials Unit: New York City<br />

This seven-year ongoing project supports the design, implementation<br />

and conduct <strong>of</strong> clinical trials in HIV/AIDS centered in several areas:<br />

antiretroviral treatment, complications <strong>of</strong> HIV/AIDS and its therapies,<br />

immune-based therapies, and co-infections such as human<br />

papillomavirus (HPV) and hepatitis B and C. A newer initiative<br />

seeks to study the HIV prevention strategy <strong>of</strong> PREP (pre-exposure<br />

prophylaxis) – administering HIV drugs to at-risk HIV-uninfected<br />

individuals to prevent them from acquiring HIV infection.<br />

Principal Investigator: R. Gulick, MD, MPH<br />

Funding: NIH<br />

HIV/AIDS Clinical Trials Unit: Port-au-Prince, Haiti<br />

This seven-year ongoing project supports clinical research in HIV/<br />

AIDS on treatment strategies, prevention <strong>of</strong> mother-to-child<br />

transmission <strong>of</strong> HIV and studies <strong>of</strong> investigational HIV vaccines.<br />

Principal Investigator: J. Pape, MD<br />

Funding: NIH<br />

Human Papillomavirus (HPV) Test and Treat in HIV-Infected<br />

Women<br />

This project will conduct a clinical trial in Africa, Peru, India<br />

and Haiti. The study will randomize women to a conventional<br />

cytology-based cervical cancer screening strategy or a novel<br />

strategy using HPV testing and cervical cryotherapy. Funded in part<br />

by the President’s Emergency Plan for AIDS Relief (PEPFAR)/NIH<br />

collaboration.<br />

Principal Investigator: T. Wilkin, MD, MPH<br />

Funding: NIH<br />

Human Papillomavirus Vaccination in HIV-1-Infected Men<br />

This study evaluated the safety and immunogenicity <strong>of</strong> the<br />

quadrivalent HPV vaccine in HIV-1-infected men. The study found<br />

that the vaccine is safe and highly immunogenic. An extension <strong>of</strong><br />

the clinical trial will evaluate whether this vaccine induces immune<br />

memory. A follow-up clinical trial is being developed that will test<br />

the efficacy <strong>of</strong> this vaccine in this population.<br />

Principal Investigator: T. Wilkin, MD, MPH<br />

Funding: NIH<br />

88 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 89


Research Highlights continued<br />

Human Papillomavirus (HPV)/HIV Co-Infection in Haiti<br />

Cervical cancer is the most common cause <strong>of</strong> cancer death in HIVinfected<br />

women in Haiti (three deaths per 1,000 patient-years) and is<br />

causally linked to HPV infection. Investigators will determine the effect<br />

<strong>of</strong> antiretroviral therapy and immune reconstitution on the natural<br />

history <strong>of</strong> HPV infection in HIV-infected women, and study the<br />

effect <strong>of</strong> HIV/HPV co-infection on prostaglandin E2, an inflammatory<br />

molecule that is an important mediator <strong>of</strong> cancer development.<br />

Principal Investigator: D. W. Fitzgerald, MD<br />

Funding: NIH<br />

Immunochemotherapy for Visceral Leishmaniasis<br />

This long-term project is directed at understanding T celldependent,<br />

macrophage-mediated host defense mechanisms<br />

in experimental Leishmania donovani infection. The goal is to<br />

combine these mechanisms with conventional chemotherapy to<br />

produce more rapid, complete initial parasite killing and prevent<br />

subsequent relapse <strong>of</strong> infection.<br />

Principal Investigator: H. W. Murray, MD<br />

Funding: NIH<br />

Influenza Research Collaboration Protocol 001: A Pilot Study<br />

for Collection <strong>of</strong> High-Titer Anti-Influenza A H1N1 2009<br />

Plasma<br />

The goal <strong>of</strong> this study is to develop a plasma product for potential<br />

therapeutic use in patients with severe H1N1 influenza. Eligible<br />

subjects (who will donate plasma by undergoing apheresis) have<br />

high levels <strong>of</strong> antibodies to the 2009 H1N1 strain <strong>of</strong> influenza<br />

either due to prior infection or vaccination.<br />

Principal Investigator: M. J. Glesby, MD, PhD<br />

Funding: NIH<br />

Metabolomics Approaches to Tuberculosis Drug<br />

Development<br />

This study proposes to apply global metabolite pr<strong>of</strong>iling approaches<br />

to deduce the mycobactericidal mechanism <strong>of</strong> action <strong>of</strong> reactive<br />

nitrogen intermediates against Mycobacterium tuberculosis.<br />

Principal Investigator: K.Y. Rhee, MD, PhD<br />

Funding: NIH<br />

Metabolomics-Based Approaches to Tuberculosis Drug<br />

Development<br />

This study proposes to develop metabolomics-based tools to<br />

enable intrabacterial pharmacokinetic and pharmacodynamic<br />

analysis <strong>of</strong> novel antimycobacterial compounds identified through<br />

whole-cell screening approaches.<br />

Principal Investigator: K.Y. Rhee, MD, PhD<br />

Funding: Bill and Melinda Gates Foundation, TB Drug Accelerator<br />

Program<br />

Metabolosome-Mediated Control <strong>of</strong> Tuberculosis Latency<br />

This study represents follow-on funding <strong>of</strong> the prior Grand<br />

Challenges Exploration award, which proposed to test the<br />

hypothesis that Mycobacterium tuberculosis operates its<br />

metabolism by regulating the assembly <strong>of</strong> metabolic modules that<br />

are organized into protein microcompartments, and that these<br />

microcompartments facilitate entry into and exit from latency.<br />

Principal Investigator: K.Y. Rhee, MD, PhD<br />

Funding: Bill and Melinda Gates Foundation, Grand Challenges<br />

Exploration<br />

KPC-Producing Enterobacteriaceae (Drug-Resistant Bacterial<br />

Infections) in New York City<br />

This project is investigating the clinical and molecular epidemiology<br />

<strong>of</strong> Klebsiella pneumoniae carbapenemase (KPC)-producing<br />

Enterobacteriaceae (KPC-E) in healthcare facilities in which these<br />

organisms have become endemic, in order to provide information<br />

that can be used in developing effective prevention strategies. The<br />

project will identify the prevalence and incidence <strong>of</strong> colonization<br />

with KPC- E among patients in various types <strong>of</strong> healthcare settings<br />

in New York City; describe the transmission dynamics <strong>of</strong> KPC-E;<br />

and identify independent predictors <strong>of</strong> colonization with KPC-E<br />

among patients.<br />

Principal Investigator: D. Calfee, MD, MS<br />

Funding: Centers for Disease Control and Prevention, Association<br />

<strong>of</strong> American Medical Colleges<br />

Malaria: Genomic Instability and Copy Number Variation<br />

This study is using new techniques for manipulating the genome<br />

<strong>of</strong> the malaria parasite to directly study the effects <strong>of</strong> copy number<br />

variation <strong>of</strong> different genes found to be amplified in field and<br />

laboratory isolates. Genes <strong>of</strong> study are implicated in parasite drug<br />

resistance.<br />

Principal Investigator: L. Kirkman, MD<br />

Funding: NIH<br />

Mechanisms <strong>of</strong> Vancomycin Resistance in Staphylococcus<br />

aureus<br />

This study investigates the use <strong>of</strong> a novel mass spectrometry-based<br />

metabolite pr<strong>of</strong>iling technique (metabolomics) to elucidate the<br />

metabolic pathways involved in the expression <strong>of</strong> vancomycin<br />

resistance in Staphylococcus aureus.<br />

Principal Investigator: E. Alexander, MD, with K. Y. Rhee, MD, PhD<br />

Funding: <strong>Weill</strong> <strong>Cornell</strong> Clinical and Translational Science Center<br />

Medical Ethics<br />

Minds Apart: Severe Brain Injury and Health Policy<br />

The major goals <strong>of</strong> this project are to explore attitudes and<br />

practices toward brain injury that will yield important lessons<br />

for the care <strong>of</strong> patients with severe brain injury, as well as other<br />

marginalized populations with chronic conditions, and to produce<br />

a book-length manuscript to inform health policy.<br />

Principal Investigator: J. J. Fins, MD<br />

Funding: The Robert Wood Johnson Foundation<br />

Neuroethics and Disorders <strong>of</strong> Consciousness II: Expanding<br />

Research Infrastructure and Scholarship<br />

We seek to assess the scope <strong>of</strong> misdiagnosis and neglect <strong>of</strong><br />

patients with disorders <strong>of</strong> consciousness, address the ethical<br />

imperative to develop new measures <strong>of</strong> diagnosis and treatment,<br />

and to aid in the development <strong>of</strong> the Center for the Advanced<br />

Study <strong>of</strong> Brain Injury (CASBI) at <strong>Weill</strong> <strong>Cornell</strong> Medical College and<br />

The Rockefeller University Hospital.<br />

Principal Investigator: J. J. Fins, MD<br />

Funding: The Buster Foundation<br />

Nephrology and Hypertension<br />

Biomolecular Markers for Safe Minimization <strong>of</strong><br />

Immunosuppression<br />

The aim <strong>of</strong> this project is to investigate whether urinary cell/<br />

peripheral blood cell/allograft mRNA/miRNA pr<strong>of</strong>iles are<br />

informative <strong>of</strong> clinical outcomes in renal allograft recipients<br />

randomized to a standard dose tacrolimus versus low dose<br />

tacrolimus regimen.<br />

Principal Investigator: M. Suthanthiran, MD<br />

Funding: NIH<br />

FoxP3 Regulatory Network mRNA Pr<strong>of</strong>iles and Human Renal<br />

Transplant Outcomes<br />

The central goal is to test the hypotheses that levels <strong>of</strong> mRNA<br />

for Foxp3 and levels <strong>of</strong> mRNAs for a mechanistically linked Foxp3<br />

regulatory gene network are predictive <strong>of</strong> post-transplant allograft<br />

function, acute rejection severity and outcome and chronic<br />

allograft nephropathy.<br />

Principal Investigator:: M. Suthanthiran, MD<br />

Funding: NIH<br />

Noninvasive Prediction and Prognostication <strong>of</strong> Acute<br />

Rejection with the Use <strong>of</strong> miRNA Pr<strong>of</strong>iles<br />

The overall objective <strong>of</strong> this study is to investigate the hypothesis<br />

that levels <strong>of</strong> urinary cell miRNAs, ascertained in urine specimens<br />

collected at the time <strong>of</strong> clinically indicated renal allograft biopsies:<br />

predict acute rejection severity and prognosticate the outcome <strong>of</strong><br />

an episode <strong>of</strong> acute rejection.<br />

Principal Investigator: M. Suthanthiran, MD<br />

Funding: NIH<br />

Noninvasive Diagnosis <strong>of</strong> BKV Nephropathy<br />

The overall objective <strong>of</strong> this study is to develop a<br />

noninvasive diagnostic test that is predictive, diagnostic and<br />

prognostic <strong>of</strong> BK virus-associated nephropathy.<br />

Principal Investigator: M. Suthanthiran, MD<br />

Funding: NIH<br />

Renal Allograft Tolerance through Mixed Chimerism<br />

The objective <strong>of</strong> this study is to achieve transient mixed chimerism<br />

and induce tolerance <strong>of</strong> HLA-mismatched human renal allograft<br />

recipients.<br />

Principal Investigator: M. Suthanthiran, MD<br />

Funding: NIH<br />

90 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 91


Research Highlights continued<br />

Biomolecular Markers Predictive/Diagnostic <strong>of</strong> Renal<br />

Allograft Status<br />

The main objective <strong>of</strong> this study is to test the hypothesis that<br />

mRNA/miRNA expression patterns <strong>of</strong> intraoperative renal allograft<br />

biopsies are predictive <strong>of</strong> acute rejection and chronic allograft<br />

nephropathy.<br />

Principal Investigator: M. Suthanthiran, MD<br />

Funding: Qatar National Research Fund<br />

Clinical Trials in Organ Transplantation: Molecular Pr<strong>of</strong>iling<br />

and Immunomodulatory Intervention (CTOT-4)<br />

The aims <strong>of</strong> this project are to investigate whether systemic and/<br />

or intragraft molecular pr<strong>of</strong>iles may be used to monitor immuneand<br />

inflammatory-mediated injury to the allograft in the setting <strong>of</strong><br />

human solid organ transplantation.<br />

Principal Investigator: M. Suthanthiran, MD (<strong>Weill</strong> <strong>Cornell</strong><br />

Molecular Core)<br />

Funding: NIH<br />

Clinical Trials in Organ Transplantation: Molecular Pr<strong>of</strong>iling<br />

and Immunomodulatory Intervention<br />

The overall objective <strong>of</strong> this study is to investigate whether<br />

circulating levels <strong>of</strong> miRNAs are diagnostic <strong>of</strong>: acute rejection <strong>of</strong><br />

liver allografts and recurrent hepatitis C.<br />

Principal Investigator: M. Suthanthiran, MD (<strong>Weill</strong> <strong>Cornell</strong><br />

Molecular Core)<br />

Funding: NIH<br />

Bypass Angioplasty Revascularization Investigation in Type 2<br />

Diabetes (BARI2D)<br />

In the Bari 2D trial, 2,368 patients with both T2DM and heart<br />

disease were randomly assigned to undergo either prompt<br />

revascularization with intensive medical therapy or intensive<br />

medical therapy alone and to undergo either insulin-sensitization or<br />

insulin-provision therapy.<br />

Principal Investigator (<strong>Weill</strong> <strong>Cornell</strong> Site): P. August, MD<br />

Funding: NIH<br />

MessengerRNA Pr<strong>of</strong>iling for the Diagnosis <strong>of</strong> Acute Rejection<br />

<strong>of</strong> Human Renal Allografts: A Validation Project<br />

The overall objective <strong>of</strong> this study is to evaluate the diagnostic<br />

utility <strong>of</strong> urinary and peripheral blood cell mRNA pr<strong>of</strong>iles for the<br />

noninvasive diagnosis <strong>of</strong> acute rejection <strong>of</strong> human renal allograft.<br />

Principal Investigator: M. Suthanthiran, MD<br />

Funding: Quest Diagnostics<br />

The Action to Control Cardiovascular Risk in Diabetes Study<br />

Group: Effects <strong>of</strong> Intensive Glucose Lowering in Type 2<br />

Diabetes<br />

In the ACCORD Study, 10,000 T2DM subjects were randomly<br />

assigned to an intensive regimen for glycemic control or standard<br />

therapy and followed by investigators for five years.<br />

Principal Investigator (<strong>Weill</strong> <strong>Cornell</strong> Site): P. August, MD<br />

Funding: NIH<br />

Targeting Inflammation Using Salsalate for Type 2 Diabetes<br />

Stage II (TNSAL –T2DM)<br />

The primary objective <strong>of</strong> this study is to determine whether<br />

salicylates represent a new pharmacological option for diabetes<br />

management.<br />

Co-Principal Investigator (<strong>Weill</strong> <strong>Cornell</strong> Site): P. August, MD<br />

Funding: NIH<br />

Nebivolol vs. Metoprolol: Comparative Effects on Fatigue<br />

and Quality <strong>of</strong> Life<br />

A frequently encountered side effect <strong>of</strong> beta-blockers is fatigue.<br />

Nebivolol, a new beta-blocker with vasodilating effects due to<br />

increased secretion <strong>of</strong> nitric oxide, appears less likely to cause side<br />

effects such as fatigue, impairment <strong>of</strong> glucose metabolism and<br />

sexual dysfunction. This study is a double-blind crossover trial <strong>of</strong><br />

nebivolol versus metoprolol (the best-selling beta-blocker), eight<br />

weeks on each drug, with the end points <strong>of</strong> fatigue and treadmill<br />

time.<br />

Principal Investigator: S. J. Mann, MD<br />

Funding: Forest Research Institute<br />

Pulmonary and Critical Care <strong>Medicine</strong><br />

Smoking-Mediated Up-Regulation <strong>of</strong> GAD 67<br />

Expression in the<br />

Human Airway Epithelium<br />

Up-regulation <strong>of</strong> airway epithelium expression <strong>of</strong> GAD 67<br />

may<br />

contribute to the increase in mucus production observed in<br />

association with cigarette smoking. In the context <strong>of</strong> these<br />

observations, it is a promising pharmacological target for inhibiting<br />

airway mucus overproduction.<br />

Principal Investigator: R. G. Crystal, MD<br />

Funding: NIH<br />

Cigarette Smoking Reprograms Apical Junctional Complex<br />

Molecular Architecture in the Human Airway Epithelium<br />

This study suggests that the overall apical junctional complex<br />

molecular architecture in the airway epithelium in COPD is<br />

reprogrammed in a smoking-dependent manner from its normal<br />

gene expression pattern essential for maintaining an appropriate<br />

barrier function toward a cancer-like molecular phenotype.<br />

Principal Investigator: R. G. Crystal, MD<br />

Funding: NIH<br />

The Air-Liquid Interface and Use <strong>of</strong> Primary Cell Cultures Are<br />

Important to Recapitulate the Transcriptional Pr<strong>of</strong>ile <strong>of</strong> In<br />

Vivo Airway Epithelia<br />

The air-liquid interface and use <strong>of</strong> primary cell cultures are<br />

important to recapitulate the transcriptional pr<strong>of</strong>ile <strong>of</strong> in vivo<br />

airway epithelia. This study focuses on the high level <strong>of</strong> similarity<br />

between cells <strong>of</strong> tracheal and bronchial origin within and between<br />

different human donors, which suggests a very robust expression<br />

pr<strong>of</strong>ile that is specific to airway. Use <strong>of</strong> primary cells for culture and<br />

the presence <strong>of</strong> an air-liquid interface play an important role in cell<br />

differentiation. These data also establish a baseline for comparing<br />

airway epithelia in health and disease.<br />

Principal Investigator: R. G. Crystal, MD<br />

Funding: NIH<br />

Smoking-Induced Up-Regulation <strong>of</strong> AKR1B10 Expression in<br />

the Airway Epithelium <strong>of</strong> Healthy Individuals<br />

The up-regulation <strong>of</strong> AKR1B10 (an aldo-keto reductase that<br />

eliminates retinals) and its function in detoxification and the<br />

retinoic acid pathway are suggestive that it may play an early role<br />

in carcinogenesis.<br />

Principal Investigator: R. G. Crystal , MD<br />

Funding: NIH<br />

Threshold <strong>of</strong> Biologic Responses <strong>of</strong> the Small Airway<br />

Epithelium to Low Levels <strong>of</strong> Tobacco Smoke<br />

This study adds to the field that an analysis <strong>of</strong> the small airway<br />

epithelial transcriptome <strong>of</strong> individuals exposed to low-dose tobacco<br />

smoke versus those not exposed demonstrates biologic changes<br />

that are likely the earliest biologic abnormalities in the lung leading<br />

to lung disease.<br />

Principal Investigator: R. G. Crystal, MD<br />

Funding: NIH and the Flight Attendant’s Medical Research Institute<br />

AAVrh.10-Mediated Genetic Delivery <strong>of</strong> Bevacizumab to the<br />

Pleura to Provide Local Anti-VEGF to Suppress Growth <strong>of</strong><br />

Metastatic Lung Tumors<br />

Study to test that AAV-mediated genetic delivery <strong>of</strong> bevacizumab<br />

(humanized monoclonal anti-VEGF antibody, approved as a<br />

treatment for non-squamous, non-small cell lung cancer) to the<br />

pleura, to deliver locally to the lung, represents a novel alternative<br />

approach to conventional monoclonal antibody therapy for<br />

metastatic lung cancer.<br />

Principal Investigator: R. G. Crystal, MD<br />

Funding: NIH<br />

Do Airway Epithelium Air-Liquid Cultures Represent the In<br />

Vivo Airway Epithelium Transcriptome?<br />

This study adds to the field that air-liquid interface cultures are<br />

useful tools to study the airway epithelium in vitro.<br />

Principal Investigator: R. G. Crystal, MD<br />

Funding: NIH and The Starr Foundation/Starr Cancer Consortium<br />

Predictors <strong>of</strong> Oxidative Stress in Heart Failure Patients with<br />

Cheyne-Stokes Respiration<br />

Study <strong>of</strong> the role <strong>of</strong> increased levels <strong>of</strong> oxidative stress in patients<br />

with heart failure and Cheyne-Stokes respiration compared with<br />

healthy controls.<br />

Principal Investigator: A. C. Krieger, MD<br />

Funding: American Heart Association National Center and NIH<br />

Acoustic Rhinometry in Pediatric Sleep Apnea<br />

This study tests the difference between obstructive sleep apnea<br />

(OSA) and primary snoring groups during acoustic rhinometry<br />

measurements <strong>of</strong> the nasopharynx. Positional airway changes were<br />

previously reported in adults with OSA and further evaluation <strong>of</strong><br />

the airway function in pediatric OSA is warranted.<br />

Principal Investigator: A. C. Krieger, MD<br />

Funding: NIH<br />

Prednisone, Azathioprine and N-Acetylcysteine: A Study<br />

That Evaluates Response in Idiopathic Pulmonary Fibrosis<br />

(PANTHER-IPF)<br />

The purpose <strong>of</strong> the PANTHER study is to determine how effective<br />

the drug N-acetylcysteine (NAC), alone and in combination with<br />

prednisone and azathioprine, is in preventing the loss <strong>of</strong> lung<br />

function in people with idiopathic pulmonary fibrosis (IPF).<br />

Principal Investigator: R. Kaner, MD<br />

Funding: NIH/NHLBI<br />

Anticoagulant Effectiveness in Idiopathic Pulmonary Fibrosis<br />

(ACEIPF)<br />

This is a randomized, double-blind, placebo-controlled, multicenter<br />

study that will compare warfarin and placebo in subjects with<br />

idiopathic pulmonary fibrosis (IPF).<br />

Principal Investigator: R. Kaner, MD<br />

Funding: NIH/NHLBI<br />

92 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 93


Research Highlights continued<br />

Adenovirus Vectors Block Human Immunodeficiency Virus-1<br />

Replication in Human Alveolar Macrophages by Inhibition <strong>of</strong><br />

the Long Terminal Repeat<br />

Study is based on our finding that Ad vectors are inhibitory to<br />

HIV-1 replication in human alveolar macrophages based, in part, on<br />

their ability to inhibit long terminal repeat-driven transcription.<br />

Principal Investigator: R. Kaner, MD<br />

Funding: NIH and the Will Rogers Memorial Fund<br />

Mechanisms <strong>of</strong> Endothelial Cell Dysfunction in Sleep Apnea<br />

Sleep apnea is a common sleep disorder characterized by<br />

temporary stops in breathing during sleep and has been associated<br />

with the development <strong>of</strong> cardiovascular disease. This research will<br />

investigate potential mechanisms leading to the development <strong>of</strong><br />

vascular problems in patients with sleep apnea.<br />

Principal Investigator: A.C. Krieger, MD, MPH<br />

Funding: NIH<br />

Sleep Bruxism and Central Sensitization in My<strong>of</strong>ascial<br />

Face Pain<br />

The purpose <strong>of</strong> this project is to evaluate the presence <strong>of</strong> sleeprelated<br />

bruxism in patients with my<strong>of</strong>ascial face pain. Patients<br />

recruited for this study undergo a battery <strong>of</strong> tests to evaluate the<br />

potential underlying mechanism for their face pain under the<br />

guidance <strong>of</strong> the Project’s Principal Investigator (Karen Raphael,<br />

PhD), followed by an overnight sleep study to assess the presence<br />

<strong>of</strong> bruxism while qualifying and quantifying facial movements.<br />

Principal Investigator (<strong>Weill</strong> <strong>Cornell</strong> Site):<br />

A.C. Krieger, MD, MPH<br />

Funding: NIH<br />

Regulation <strong>of</strong> Vascular Thrombosis in Sleep Apnea<br />

This study investigates the presence <strong>of</strong> a specific genetic<br />

polymorphism in patients with sleep apnea as compared to<br />

healthy controls. This polymorphism causes the production <strong>of</strong><br />

an alternative form <strong>of</strong> deaminase, which may alter patients’<br />

susceptibility to developing vascular thrombosis.<br />

Principal Investigator: A.C. Krieger, MD, MPH<br />

Funding: Robert Wood Johnson Foundation<br />

Mechanism <strong>of</strong> aPL Antibody-induced Pregnancy Loss<br />

The major goals <strong>of</strong> this project are to determine which<br />

complement components and receptors are necessary or sufficient<br />

to mediate aPL antibody-induced placental injury, fetal loss and/or<br />

IUGR and to define the role <strong>of</strong> aPL antibody-mediated complement<br />

activation within the overall inflammatory cascade in order to<br />

identify complement-dependent versus complement-independent<br />

mechanisms.<br />

Principal Investigator: J. E. Salmon, MD<br />

Funding Agency: NIH/NIAID (RO1 AR 38889)<br />

(07/01/2007- 6/30/2011)<br />

Indirect Inhibition <strong>of</strong> Toll-Like Receptor and Type I Interferon<br />

Responses by ITAM-Coupled Receptors and Integrins<br />

An important function <strong>of</strong> immunoreceptor tyrosine-based<br />

activation motif (ITAM)-coupled receptors is cross-regulation<br />

<strong>of</strong> heterologous receptor signaling, but mechanisms <strong>of</strong> crossinhibition<br />

are poorly understood.<br />

Principal Investigator: L. B. Ivashkiv, MD<br />

Funding: NIH<br />

Phosphorylation <strong>of</strong> IRF4 by ROCK2 Regulates IL-17 and IL-21<br />

Production and the Development <strong>of</strong> Autoimmunity in Mice<br />

Deregulated production <strong>of</strong> IL-17 and IL-21 plays a key pathogenic<br />

role in many autoimmune disorders. A delineation <strong>of</strong> the<br />

mechanisms that underlie the inappropriate synthesis <strong>of</strong> IL-17 and<br />

IL-21 in autoimmune diseases can thus provide important insights<br />

into potential therapies for these disorders. We have shown that<br />

the serine-threonine kinase Rho-associated, coiled-coil-containing<br />

protein kinase 2 (ROCK2) becomes activated in mouse T cells under<br />

Th17 skewing conditions and phosphorylates interferon regulatory<br />

factor 4 (IRF4), a transcription factor that is absolutely required<br />

for the production <strong>of</strong> IL-17 and IL-21. Our findings uncovered a<br />

crucial link among ROCK2, IRF4 and the production <strong>of</strong> IL-17 and<br />

IL-21, supporting the idea that selective inhibition <strong>of</strong> ROCK2 could<br />

represent an important therapeutic regimen for the treatment <strong>of</strong><br />

autoimmune disorders.<br />

Principal Investigator: A. Pernis, MD<br />

Funding: NIH<br />

Medical<br />

Education<br />

Rheumatology<br />

Predictors <strong>of</strong> Response to TNF Antagonist Therapy in<br />

Rheumatoid Arthritis<br />

Despite substantial clinical efficacy <strong>of</strong> tumor necrosis factor-a<br />

(TNF)-antagonist therapy in patients with rheumatoid arthritis (RA),<br />

some patients respond poorly to such agents. Since an interferon<br />

(IFN) signature is variably expressed among RA patients, the study<br />

is designed to investigate whether plasma type I IFN activity might<br />

predict response to TNF-antagonist therapy.<br />

Principal Investigator: M. K. Crow, MD<br />

Funding: NIH<br />

Predictors <strong>of</strong> Pregnancy Outcome in SLE and APS<br />

A prospective observational study <strong>of</strong> over 400 pregnant<br />

patients, enrolled at 6 major medical centers, grouped and<br />

analyzed according to the presence <strong>of</strong> aPL and preexisting SLE to<br />

provide insights into the mechanisms <strong>of</strong> complement-mediated<br />

inflammatory disorders and to suggest means to prevent, arrest, or<br />

modify these conditions.<br />

Principal Investigator: J. E. Salmon, MD<br />

Co-Investigator: M.D. Lockshin, MD<br />

Funding: NIH/NIAMS (12/01/2003-11/30/2012)<br />

WCIMA<br />

Small Changes and Lasting Effects (SCALE) Minority<br />

Investigator Research Supplement<br />

Examines the association between body image discrepancy, health<br />

risk knowledge <strong>of</strong> obesity, and success with weight loss in the<br />

SCALE trial parent grant.<br />

Principal Investigator: G. Winston, MD<br />

Funding: NHLBI<br />

Integrating Transdisciplinary Education at <strong>Cornell</strong>/Hunter –<br />

ITEACH<br />

This collaboration between <strong>Weill</strong> <strong>Cornell</strong> Medical College and three<br />

Hunter College schools (Nursing, Public Health, and Social Work)<br />

proposes to design and institutionalize a program <strong>of</strong> integrated,<br />

interpr<strong>of</strong>essional educational experiences that will provide medical<br />

students and nursing, public health, and social work students with<br />

new competencies in collaborative teamwork. This initiative will<br />

expose students <strong>of</strong> different disciplines to hospital and clinic-based<br />

care, community outreach, and interdisciplinary care in the home<br />

setting at a very early point in their training.<br />

Principal Investigators: C. Storey-Johnson, MD (<strong>Weill</strong> <strong>Cornell</strong>)<br />

and J. Griffin-Sobel, PhD, RN<br />

Funding: Josiah Macy, Jr. Foundation<br />

94 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Co-Chief, Dr. Devang Dave (2010); Dr. Lia Logio (Director, Internal <strong>Medicine</strong> Residency Program; Co-Chief, Dr. Won Kim (2010) Annual Report 2011 95


Residents and Fellows<br />

on the Move…<br />

Kunal Karia, MD, Resident<br />

When I reflect upon the journey <strong>of</strong> becoming an intern, I am reminded <strong>of</strong> Robert Frost’s “The Road<br />

Not Taken.” I started residency training in pathology but quickly realized my true passion resided in<br />

clinical medicine and made the unconventional move to switch residencies. I chose NYP-<strong>Weill</strong> <strong>Cornell</strong><br />

because <strong>of</strong> its tremendous faculty, diverse patient population, unlimited array <strong>of</strong> research opportunities,<br />

and the camaraderie <strong>of</strong> the house staff. The <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> has surpassed my expectations<br />

with wonderful didactic conferences, clinical teaching, and support from program leadership to make<br />

changes the residents feel are important. I couldn’t have imagined a smoother transition, and though I<br />

took the road less traveled, choosing NYP-WC has made all the difference.<br />

Nikhil Kumta, MD, Resident<br />

I have been impressed with the commitment <strong>of</strong> the faculty to providing the highest quality <strong>of</strong> patient<br />

care and medical education. The volume <strong>of</strong> patients and diversity <strong>of</strong> diseases provide an enriched clinical<br />

experience that is unparalleled. Training here affords the opportunity to not only learn about the “bread<br />

and butter” <strong>of</strong> medicine, but allows exposure to more rare entities. I have been particularly impressed<br />

with the work ethic <strong>of</strong> my peers, who are equally devoted to patient care and education, yet still find time<br />

to conduct and present research at national conferences. The camaraderie among the residents<br />

is truly one <strong>of</strong> the strengths <strong>of</strong> the program. Living in New York City is simply amazing.<br />

No matter what your interests are, there is always something to do – sports, food, fashion,<br />

or the arts. Your precious free time is never wasted!<br />

(L) Dr. Kumta (R) Dr. Karia<br />

Patricia Myers-Gurevitch, MD, Resident<br />

When I interviewed for a position in Internal <strong>Medicine</strong> Residency, I was searching for a program that would <strong>of</strong>fer me a well-rounded<br />

education, be intellectually stimulating as well as challenging, and give me the opportunity to provide care to a diverse patient<br />

population. I also wanted to become an integral part <strong>of</strong> the medical team that would give me autonomy to develop my unique style<br />

as a physician. I have found <strong>Weill</strong> <strong>Cornell</strong> to be the perfect match. I love the institution and have felt instantly comfortable here.<br />

We are given a balance <strong>of</strong> responsibility and autonomy throughout the training experience. The daily lectures and conferences are<br />

led by attending physicians who are leaders in their fields. My colleagues also contribute to the quality <strong>of</strong> education, each <strong>of</strong> them<br />

bringing with them varied educational and research experience. We complement one another. The residency program includes<br />

traditional and unique possibilities for inpatient and outpatient rotations, with options for both rural and international health<br />

electives. Many <strong>of</strong> us plan a rotation during our 3 rd year <strong>of</strong> residency at a medical facility associated with <strong>Weill</strong> <strong>Cornell</strong> in Eastern<br />

Africa. All this opportunity is provided to me, as I live in one <strong>of</strong> the greatest cities in the world! I have found <strong>Weill</strong> <strong>Cornell</strong> has<br />

<strong>of</strong>fered me the building blocks necessary to succeed as I plan for a demanding fellowship in Nephrology.<br />

96 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 97


John Egan, MD, Resident<br />

As I advance in my training and evolve as a physician, I have found it helpful to stop and reflect on what<br />

values originally led me to pursue a career in medicine: love <strong>of</strong> humanity and pursuit <strong>of</strong> the truth. Every day<br />

I find these values are supported at <strong>Weill</strong> <strong>Cornell</strong>. The house staff and faculty are incredibly dedicated to the<br />

needs <strong>of</strong> our patients, and I have always been supported in making decisions I felt were in the best interest<br />

<strong>of</strong> my patient. There is a true commitment to medical education and advancing research. Whether it be on<br />

attending rounds, at noon conference, or just running a case by a fellow resident, there is always something<br />

new to learn. House staff research is also strongly supported and encouraged. I have been fortunate enough<br />

to work with two different attendings on projects I contributed to, even as a busy resident.<br />

Annie Garment, MD, Assistant Chief Resident Primary Care<br />

I originally applied for and matched in <strong>Weill</strong> <strong>Cornell</strong>’s “categorical” medicine residency, a traditional program<br />

focused on hospital medicine. But by the end <strong>of</strong> my intern year, having spent two months in the outpatient setting,<br />

I transferred into the Primary Care Track to focus my training on ambulatory care. Inspired by the academic rigor and<br />

compassionate care demonstrated by so many <strong>of</strong> our outpatient attending physicians, I have subsequently had the<br />

great fortune to work with them as a trainee and an Assistant Chief Resident. None <strong>of</strong> us knows exactly what primary<br />

care in America will look like in the years to come. We do know that being a primary care provider will mean much<br />

more than serving as a gatekeeper. It will require practicing true evidence-based medicine, considering a vast array <strong>of</strong><br />

socioeconomic factors in caring for individuals, and realizing how our decision-making patterns will affect society as<br />

a whole. My outpatient training experience has motivated me to pursue a career as a primary care clinician educator<br />

and has prepared me for taking on whatever the future may bring for primary care in America.<br />

98 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 99


Joseph Marmora, MD, Resident<br />

There are obvious reasons for pursuing residency training at <strong>Weill</strong> <strong>Cornell</strong>. The bustling hospital<br />

is a leader in our nation’s largest city; the training experience is unique and challenging; the<br />

accomplished staff <strong>of</strong>fers a first-rate medical education; and world-class resources facilitate<br />

the finest care a patient could receive. Then there is the reason that is more subtle, but most<br />

compelling: there are simply good people here. Talented people, compassionate people,<br />

dedicated people who drive me to become better, who have taught me that above all else is<br />

the patient. It is something I uncovered at my initial interview here, and it is the primary reason<br />

I sought a spot in the program. I am frankly awed by what my predecessors and peers have<br />

created and continue to create here.<br />

Paula Roy-Burman, MD, Resident<br />

As we adjust our lenses to reflect upon our own national health care system, we also shift focus to transcend<br />

national borders and consider populations on a global scale. With increasing successes in maternal-fetal health<br />

and infectious disease, life expectancies in the third world are extending. Strategizing how we can create<br />

reliable avenues <strong>of</strong> health care in the third world is where my pr<strong>of</strong>essional interest falls. <strong>Cornell</strong> University and<br />

WCMC were early adopters in the field <strong>of</strong> Global Health. I was initially drawn to the NYP-WCMC <strong>Medicine</strong><br />

program for the breadth <strong>of</strong> structured opportunity <strong>of</strong>fered in the nations <strong>of</strong> Brazil, Haiti and Tanzania in<br />

addition to scholarships available to pursue non-affiliated projects. I recall once coming upon a young refugee<br />

at the Thai-Burmese border. She had a red rash bridging across her nose and involving both cheeks. The team<br />

<strong>of</strong> medics, well-versed in landmine wounds, malaria and tuberculosis, were perplexed -- was it cellulitis? As it<br />

turned out, it was lupus. I look forward to a time when non-infectious diseases, be it coronary artery disease or<br />

diabetes, can be managed despite geographic limitations.<br />

100 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 101


Jonathan Gordin, MD, Resident<br />

As a medical student at the <strong>Weill</strong> <strong>Cornell</strong> Medical College,<br />

I was excited at the prospect <strong>of</strong> a residency in the Internal<br />

<strong>Medicine</strong> program, and the past six months have not<br />

disappointed. The most striking aspect has been the<br />

atmosphere <strong>of</strong> collegiality and teamwork. Rounds focus<br />

on the combined goals <strong>of</strong> excellent clinical education and<br />

unparalleled patient care. The extended multidisciplinary<br />

team helps facilitate the complex management <strong>of</strong> healthcare<br />

beyond that <strong>of</strong> mere diagnosis and treatment. Our program<br />

leaders have continuously reached out to the house staff<br />

on both the informal and formal levels for comments and<br />

feedback, and they have implemented suggested changes for<br />

the better. Our program encourages us to follow through on<br />

our research interests, gives us ample elective time in our first<br />

year, and provides us with the means to get connected with<br />

investigators – I was even able to present work at a major<br />

conference as an intern.<br />

Jyoti Mathad, MD, Fellow, Infectious Diseases<br />

I chose NYP-<strong>Weill</strong> <strong>Cornell</strong>’s Division <strong>of</strong> Infectious Diseases for my<br />

fellowship because <strong>of</strong> their long track record <strong>of</strong> groundbreaking<br />

work in such far-flung locations as Brazil, Tanzania, and Haiti.<br />

While I knew the hospital’s global research presence would set<br />

me on the right track for a career in international health, I’ve<br />

been particularly impressed by the broad exposure to rare and<br />

emerging diseases I’ve received during my clinical year here in<br />

New York City. I see a diverse patient population with diseases<br />

both typical and tropical, including several that most doctors<br />

only know from textbooks. Those experiences gave me the<br />

skills I needed to establish my own research project in India<br />

-- an endeavor that the department has supported tirelessly.<br />

Even when I’m 8,000 miles and ten time zones away, the<br />

faculty are always available and willing to <strong>of</strong>fer their wisdom.<br />

The collaborative spirit I have experienced at NYP-<strong>Weill</strong> <strong>Cornell</strong><br />

will be instrumental in forging my own career in international<br />

infectious diseases.<br />

102 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 103


2010 Graduate<br />

Medical Education<br />

Residency Training Program<br />

The NewYork-Presbyterian Hospital/<strong>Weill</strong> <strong>Cornell</strong> Internal<br />

<strong>Medicine</strong> Residency Program has a long-standing tradition <strong>of</strong><br />

excellence in its commitment to training physician-leaders.<br />

The residency program’s 36-month curriculum provides rich<br />

opportunities to learn clinical medicine in both the inpatient<br />

and outpatient setting as well as an environment for academic<br />

scholarship. Our graduates are highly capable physicians<br />

whichever career trajectory they choose – clinical educator,<br />

physician-scientist or academic clinician.<br />

The faculty in the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> provides teaching<br />

with an emphasis on bedside learning and evidence-based<br />

practice. The daily morning report is a favorite <strong>of</strong> the house<br />

staff, when they get to generate broad differential diagnoses<br />

or delve into the nuances <strong>of</strong> management issues for complex<br />

adult patients. The patient population is multicultural with a<br />

broad array <strong>of</strong> presentations <strong>of</strong> human disease that provide<br />

a phenomenal educational milieu for trainees. Both clinical<br />

and nonclinical rotations include unique features that support<br />

innovative research projects, mentorship by renowned<br />

investigators and interaction with expert faculty. Forty-three<br />

positions were filled in 2009–2010: four each in primary care<br />

and medical research, along with 35 categorical positions.<br />

Residents-in-training benefit from our strong affiliations<br />

with the three other premier institutions immediately adjacent<br />

to the hospital, creating one <strong>of</strong> the world’s great academic<br />

medical communities: Memorial Sloan-Kettering Cancer Center,<br />

the Hospital for Special Surgery and The Rockefeller University<br />

Hospital. Medical house staff rotate through the medical and<br />

neurological services at the NewYork-Presbyterian Hospital/<strong>Weill</strong><br />

<strong>Cornell</strong> Medical Center, the preeminent rheumatology service at<br />

the Hospital for Special Surgery and various medical oncology<br />

services at Memorial Sloan-Kettering Cancer Center. These<br />

sites expose our residents to an extraordinarily diverse patient<br />

population in all areas <strong>of</strong> internal medicine. Though common<br />

diseases predominate, residents also encounter a wide range<br />

<strong>of</strong> rare and unusual clinical problems. All rotations emphasize<br />

independent, clinical decision-making, critical thinking and best<br />

practices. Innovations within the curriculum focus on patient<br />

safety, quality improvement, transition-<strong>of</strong>-care practices and<br />

teamwork training.<br />

Research and Global Health Opportunities<br />

Residents in the NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong><br />

Campus) Graduate Training Program have a unique opportunity<br />

to participate in ongoing research at some <strong>of</strong> the world’s foremost<br />

settings for academic medicine: <strong>Weill</strong> <strong>Cornell</strong> Medical College,<br />

The Rockefeller University, Memorial Sloan-Kettering Cancer<br />

Center and the Hospital for Special Surgery. This year, 20 to<br />

25 residents conducted research projects, 12 <strong>of</strong> which were<br />

submitted for the David E. Rogers Memorial Research Award. The<br />

recipient and finalists <strong>of</strong> this award present their work at Medical<br />

Grand Rounds. Senior residents are encouraged to do a rotation<br />

at <strong>Weill</strong> Bugando Medical Center in Tanzania. This is a challenging<br />

learning experience under the tutelage <strong>of</strong> full-time faculty<br />

from <strong>Weill</strong> <strong>Cornell</strong> Medical College. In addition, the Division <strong>of</strong><br />

Infectious Diseases sponsors research electives in Brazil and Haiti,<br />

among other overseas locations.<br />

104 (Center) <strong>Department</strong> Dr. Erica Jones <strong>of</strong> <strong>Medicine</strong> with residents in training. Annual Report 2011 105


2010 Graduate Medical Education continued<br />

Current Residents<br />

Chief Residents<br />

Devang Dave, Tufts University SOM<br />

Won Kim, <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Senior Residents (PGY3)<br />

Rini Abraham, New Jersey Medical School/UMDNJ<br />

Subhi AlAref, <strong>Weill</strong> <strong>Cornell</strong> Medical College, Qatar<br />

Kelly Axsom, Temple University SOM<br />

Oren Bernheim, Albert Einstein COM, Yeshiva University<br />

Sonica Bhatia, RW Johnson Medical School/UMDNJ<br />

Jill Blumenthal, <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

James Calloway, SUNY–Syracuse<br />

Delia Calo, SUNY–Stony Brook<br />

Marianne Camargo, New Jersey Medical School/UMDNJ<br />

Jonathan Clarke, Harvard Medical School<br />

Sean Collins, <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Brian Cullingford, Georgetown University SOM<br />

Elan Diamond, <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Brian Eiss, Georgetown University SOM<br />

Laura Fanucchi, Emory University SOM<br />

Ann Garment, New York University SOM<br />

Ari Grinspan, Albert Einstein COM, Yeshiva University<br />

Lindsay Lally, <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Jean Lee, Albert Einstein COM, Yeshiva University<br />

Deborah Yvette Lim, Temple University SOM<br />

Julie MacPhee, Albert Einstein COM, Yeshiva University<br />

Kathleen Mahoney, University <strong>of</strong> Connecticut SOM<br />

Barbara Mendez, SUNY–Buffalo<br />

Lourdes Mendez, Albert Einstein COM, Yeshiva University<br />

Tshaka Muchiteni, University <strong>of</strong> North Carolina SOM<br />

Samantha Nazareth, Brown University SOM<br />

Marissa Newman, RW Johnson Medical School/UMDNJ<br />

Crystal North, University <strong>of</strong> Washington<br />

Alyssa Parian, New Jersey Medical School/UMDNJ<br />

Charlesse Pondt, New Jersey Medical School/UMDNJ<br />

Lhasa Ray, Albert Einstein COM, Yeshiva University<br />

Gabrie Rebick, McGill University Faculty <strong>of</strong> <strong>Medicine</strong>, Canada<br />

Elizabeth Schulman, SUNY–Stony Brook<br />

Ummara Shah, University <strong>of</strong> Rochester School <strong>of</strong> <strong>Medicine</strong><br />

and Dentistry<br />

Albert Shieh, <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Magdalena Slosar, University <strong>of</strong> Massachusetts Medical School<br />

Aaron Small, Mayo Medical School<br />

Kakra Soadwa, University <strong>of</strong> Pittsburgh SOM<br />

Sasha Stanton, Albert Einstein COM, Yeshiva University<br />

Raja Taunk, New Jersey Medical School/UMDNJ<br />

Florian Toegel, University <strong>of</strong> Hamburg, Germany<br />

Amy Tyberg, New York Medical College<br />

Jacqueline Yuen, University <strong>of</strong> Michigan Medical School<br />

Benjamin Zaniello, University <strong>of</strong> Kentucky COM<br />

Junior Residents (PGY2)<br />

Melissa Accordino, Penn State COM<br />

Jose Aleman, Harvard Medical School<br />

John Allan, Saint Louis University SOM<br />

Brian Anderson, The George Washington University SOMHS<br />

Medha Barbhaiya, <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Nisha Bavalia, RW Johnson Medical School/UMDNJ<br />

Samantha Brenner, New York University SOM<br />

Scott Cameron, SUNY–Syracuse<br />

Sean Campbell, Albert Einstein COM, Yeshiva University<br />

Liesl Carey, Drexel University COM<br />

Andrew Cohen, University <strong>of</strong> Pennsylvania SOM<br />

Samantha Dias, New York Medical College<br />

John Egan, The George Washington University SOMHS<br />

Obinna Eneanya, RW Johnson Medical School/UMDNJ<br />

Jarett Feldman, The George Washington University SOMHS<br />

Viviana Figueroa Diaz, Boston University SOM<br />

James Flory, University <strong>of</strong> Pennsylvania SOM<br />

Peter Forsberg, University <strong>of</strong> Colorado SOM<br />

Swathi Gopalakrishnan, SUNY–Buffalo<br />

Scott Greenberg, University <strong>of</strong> Colorado SOM<br />

Poonam Hosamani, Feinberg SOM, Northwestern University<br />

Andrew Intlek<strong>of</strong>er, University <strong>of</strong> Pennsylvania SOM<br />

Flonza Isovski, New York University SOM<br />

Connie Jung, University <strong>of</strong> Illinois COM<br />

Nikhil Kumta, Jefferson Medical College, Thomas Jefferson University<br />

Tara Lautenslager, RW Johnson Medical School/UMDNJ<br />

Chung Han (Joe) Lee, University <strong>of</strong> Michigan Medical School<br />

Daneng Li, <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Eugene Licht, <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Susanne Luedtke, Humboldt University, Germany<br />

Lauren Maragh, Case Western Reserve University SOM<br />

Ashley Maranino, Albert Einstein COM, Yeshiva University<br />

Mamta Mehta, SUNY Downstate Medical Center<br />

Neha Mehta, Feinberg SOM, Northwestern University<br />

Patricia Myers-Gurevitch, Wayne State University SOM<br />

Shaji Philip, Jefferson Medical College, Thomas Jefferson University<br />

Ravin Ratan, Tufts University SOM<br />

Farid Razavi, New York Medical College<br />

Paula Roy-Burman, Keck SOM, University <strong>of</strong> Southern California<br />

Geethan Sivananthan, New Jersey Medical School/UMDNJ<br />

Aaron Viny, Case Western Reserve University SOM<br />

Ethan Weinberg, University <strong>of</strong> Maryland SOM<br />

Joshua Weisbrot, Albany Medical College<br />

Melanie Zuo, The University <strong>of</strong> Texas Medical School at Houston<br />

Interns (PGY1)<br />

Daniel Amoruso, New Jersey Medical School/UMDNJ<br />

Muhamed Baljevic, <strong>Weill</strong> <strong>Cornell</strong> Medical College, Qatar<br />

Karl Bezak, Vanderbilt University SOM<br />

Dara Bier, Albert Einstein COM, Yeshiva University<br />

Isaac Bowman, University <strong>of</strong> Texas Southwestern Medical School<br />

Natalie Cheng, University <strong>of</strong> Rochester SOMD<br />

Augustine Chung, Case Western Reserve University SOM<br />

Robert Daly, Harvard Medical School<br />

Anthony Daniyan, Miller SOM, University <strong>of</strong> Miami<br />

Mark Diamond, Washington University SOM in St. Louis<br />

David Fernandez, SUNY – Syracuse<br />

Timothy Ferng, Wayne State University SOM<br />

Eugene Festa, New Jersey Medical School/UMDNJ<br />

Jessica Furst, Albert Einstein COM, Yeshiva University<br />

Jacob Glass, Albert Einstein COM, Yeshiva University<br />

Timothy Glew, Tulane University SOM<br />

Jonathan Gordin, <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Parag Goyal, University <strong>of</strong> Massachusetts Medical School<br />

Elizabeth Greig, Miller SOM, University <strong>of</strong> Miami<br />

Leon Igel, Albert Einstein COM, Yeshiva University<br />

Kunal Karia, Virginia Commonwealth University SOM<br />

Scott Kramer, <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Joseph Krepp, SUNY–Stony Brook<br />

Dr. Emil Kuriakose (fellow)<br />

Michael Lerario, University <strong>of</strong> Pennsylvania SOM<br />

Andrea Li, Vanderbilt University SOM<br />

Frank Lin, Albany Medical College<br />

Lenette Lu, Case Western Reserve University SOM<br />

Carolina Maciel, Fluminense Federal University, Brazil<br />

Justin Marcus, Miller SOM, University <strong>of</strong> Miami<br />

Sharayne Mark, University <strong>of</strong> Rochester SOMD<br />

Joseph Marmora, Stritch SOM, Loyola University Chicago<br />

Alexander Merkler, New York University SOM<br />

John Morris, University <strong>of</strong> Maryland SOM<br />

Michael Mulock, Jefferson Medical College, Thomas Jefferson University<br />

Karla Nieves, University <strong>of</strong> Puerto Rico SOM<br />

Olanma Okoji, The George Washington University SOMHS<br />

Vikram Palanivel, University <strong>of</strong> Pennsylvania SOM<br />

Chiti Parikh, RW Johnson Medical School/UMDNJ<br />

Stephen Rotman, New York Medical College<br />

Kira Ryskina, Mount Sinai Medical Center, New York University<br />

Rachel Sanford, Harvard Medical School<br />

Lourdes Sanso, New York University SOM<br />

Maryam Shafaee, <strong>Weill</strong> <strong>Cornell</strong> Medical College, Qatar<br />

Stephanie Tang, Feinberg SOM, Northwestern University<br />

Louis Waldman, University <strong>of</strong> Pennsylvania SOM<br />

Frances West, Jefferson Medical College, Thomas Jefferson University<br />

Casey Wong, <strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

Micheas Zemedkun, Harvard Medical School<br />

Class <strong>of</strong> 2011<br />

Subspecialty Fellowship Appointments<br />

Cardiology<br />

Kelly Axsom<br />

New York University, New York, NY<br />

Scott Cameron*<br />

University <strong>of</strong> Rochester Medical Center, Rochester, NY<br />

Jonathan Clarke<br />

Massachusetts General Hospital, Boston, MA<br />

Tshaka Muchiteni<br />

Montefiore Medical Center, Bronx, NY<br />

Endocrinology<br />

Jose Aleman*<br />

NewYork-Presbyterian Hospital/<strong>Weill</strong> <strong>Cornell</strong> Medical Center<br />

James Flory*<br />

NewYork-Presbyterian Hospital/<strong>Weill</strong> <strong>Cornell</strong> Medical Center<br />

Gastroenterology<br />

Rini Abraham<br />

New York University, New York, NY<br />

Oren Bernheim<br />

Mount Sinai Medical Center, New York, NY<br />

Delia Calo<br />

Memorial Sloan-Kettering Cancer Center, New York, NY<br />

Ari Grinspan<br />

Mount Sinai Medical Center, New York, NY<br />

Alyssa Parian<br />

The Johns Hopkins Hospital, Baltimore, MD<br />

Aaron Small<br />

University <strong>of</strong> Pennsylvania, Philadelphia, PA<br />

Raja Taunk<br />

Lenox Hill Hospital, New York, NY<br />

Amy Tyberg<br />

Westchester Medical Center, Valhalla, NY<br />

Ethan Weinberg*<br />

NewYork-Presbyterian Hospital/<strong>Weill</strong> <strong>Cornell</strong> Medical Center<br />

Hematology and Medical Oncology<br />

Andrew Intlek<strong>of</strong>er*<br />

Memorial Sloan-Kettering Cancer Center, New York, NY<br />

Jean Lee<br />

Memorial Sloan-Kettering Cancer Center, New York, NY<br />

Joe Lee*<br />

Memorial Sloan-Kettering Cancer Center, New York, NY<br />

Kathleen Mahoney<br />

Beth Israel Deaconess Medical Center, Boston, MA<br />

Lourdes Mendez<br />

Beth Israel Deaconess Medical Center, Boston, MA<br />

Charlesse Pondt<br />

Montefiore Medical Center, Bronx, NY<br />

Sasha Stanton<br />

University <strong>of</strong> Washington Medical Center, Seattle, WA<br />

106 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 107


2010 Graduate Medical Education continued<br />

Infectious Disease<br />

Jill Blumenthal<br />

University <strong>of</strong> California, San Diego Medical Center, San Diego, CA<br />

Gabriel Rebick<br />

University <strong>of</strong> Toronto, Toronto, Canada<br />

Magdalena Slosar<br />

Montefiore Medical Center, Bronx, NY<br />

Ben Zaniello<br />

University <strong>of</strong> Washington Medical Center, Seattle, WA<br />

Rheumatology<br />

Lindsay Lally<br />

Hospital for Special Surgery, New York, NY<br />

Barbara Mendez<br />

New York University, New York, NY<br />

*Medical Research Track<br />

Fellowships<br />

The <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> <strong>of</strong>fers a variety <strong>of</strong> fellowship training<br />

opportunities in each <strong>of</strong> our divisions. All <strong>of</strong> our fellowships<br />

emphasize clinical and research training. These programs provide<br />

a challenging educational experience under the supervision and<br />

guidance <strong>of</strong> noted experts in their fields and demonstrate our<br />

commitment to ensuring that our physicians-in-training emerge<br />

as tomorrow’s leaders in their chosen fields.<br />

Cardiology<br />

Under the auspices <strong>of</strong> the Maurice R. and Corinne P. Greenberg<br />

Division <strong>of</strong> Cardiology, this three- or four-year program prepares<br />

highly qualified candidates for careers in investigative and clinical<br />

cardiology. Fellows receive comprehensive experience in all major<br />

clinical and laboratory aspects <strong>of</strong> contemporary cardiology under<br />

the close supervision <strong>of</strong> full-time staff. Each fellow is expected to<br />

participate in one or more areas <strong>of</strong> ongoing research during their<br />

training. Clinical care is the focus <strong>of</strong> the first two years, while<br />

the third and fourth years involve a more intensive, mentored<br />

experience in a particular clinical subspecialty or in basic research.<br />

An additional year (or more) <strong>of</strong> training/research in a subspecialty<br />

area can be arranged, as indicated/appropriate.<br />

Program Director: Erica C. Jones, MD<br />

Program Coordinator: Lisa Brooks, (212) 746-2218<br />

Duration <strong>of</strong> Training: 3 years<br />

Number <strong>of</strong> Positions: 19<br />

2010–2011 Fellows<br />

George Bell, MD<br />

The University <strong>of</strong> Chicago Hospital<br />

Seth Bender, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Ryan Broderick, MD<br />

Brigham and Women’s Hospital<br />

Konstantinos Charitakis, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus); Venizeleion<br />

Hospital, Greece<br />

Abiola Dele-Michael, MD, MPH<br />

University <strong>of</strong> Michigan Hospital<br />

James Horowitz, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Albert Jung, MD, PhD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Arvindh Kanagasundram, MD<br />

Stanford University Hospital<br />

Maria Karas, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Helina Kassahun, MD<br />

The Johns Hopkins Hospital<br />

Joseph Lee, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Alex Mauskop, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Danielle Nicolo, MD, PhD<br />

Temple University Hospital<br />

Lynn Punnoose, MD<br />

Brigham and Women’s Hospital<br />

Lisa Rosenbaum, MD<br />

Massachusetts General Hospital<br />

Ashish Shah, MD<br />

NewYork-Presbyterian Hospital (Columbia Campus)<br />

Rajesh Swaminathan, MD<br />

Massachusetts General Hospital<br />

Sean Wilson, MD<br />

Harvard University/Winthrop University Hospital<br />

David Yang, MD<br />

Brigham and Women’s Hospital<br />

Cardiology Brooklyn Program<br />

Program Director: Frank Iacovone, Jr., MD<br />

Program Coordinator: Julie Quinonex, (718) 250-6952<br />

2010–2011 Fellows<br />

Brooklyn Hospital Center:<br />

Amgad Botros<br />

Samir Garyali<br />

Sameer Kaul<br />

Praveen Kormerla<br />

Chirag Patel<br />

Mohammad Ansari<br />

Beth Israel Medical Center<br />

Clinical Cardiac Electrophysiology (CCEP)<br />

This fellowship within the Maurice R. and Corinne P. Greenberg<br />

Division <strong>of</strong> Cardiology provides advanced training in all aspects<br />

<strong>of</strong> invasive electrophysiology. Fellows attain expertise in catheter<br />

ablation <strong>of</strong> complex arrhythmias, including atrial fibrillation<br />

and ventricular tachycardias, as well as device implantation and<br />

management, with an emphasis on implantable defibrillators and<br />

cardiac resynchronization. The core <strong>of</strong> the fellowship consists <strong>of</strong><br />

(2nd from L) Clinical Co-Director (WCCC), Daniel Belkin, MD (Class <strong>of</strong> 2012)<br />

108 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

Annual Report 2011 109


2010 Graduate Medical Education continued<br />

rotations in the Invasive Electrophysiology Laboratory, but fellows<br />

also rotate through the device clinic and inpatient and outpatient<br />

consultations. Fellows also participate in the ongoing basic and<br />

clinical research programs conducted within the electrophysiology<br />

laboratory.<br />

Program Director: Steven Markowitz, MD<br />

Program Coordinator: Lisa Brooks, (212) 746-2218<br />

Duration <strong>of</strong> Training: 1 year<br />

Number <strong>of</strong> Positions: 3<br />

are actively involved in shaping their education, gain hands-on<br />

experience teaching residents and medical students and receive<br />

individualized instruction from nationally renowned clinicians and<br />

researchers. As appropriate, fellows may continue their training<br />

with an optional third year devoted to further research.<br />

Program Director: David Brillon, MD<br />

Program Coordinator: Helen Carey, (212) 746-9939<br />

Duration <strong>of</strong> Training: 2 years<br />

Number <strong>of</strong> Positions: 4<br />

2010–2011 Fellows<br />

Jeffrey Chung, MD<br />

Massachusetts General Hospital<br />

James Ip, MD<br />

Brigham and Women’s Hospital<br />

Seth Lessner, MD<br />

Yale New Haven Hospital<br />

Interventional Cardiology<br />

A one-year advanced training fellowship in all aspects <strong>of</strong><br />

interventional cardiology is also available through the Maurice R.<br />

and Corinne P. Greenberg Division <strong>of</strong> Cardiology. The program<br />

emphasizes a systematic, evidence-based approach to diagnostic<br />

and therapeutic coronary procedures, and enables fellows to<br />

develop expertise in pre- and postprocedural patient care in<br />

both inpatient and outpatient settings. Fellows are trained to<br />

perform percutaneous coronary interventions using state-<strong>of</strong>-theart<br />

technologies, and are expected to participate in active clinical<br />

research efforts.<br />

Program Director: Robert Minutello, MD<br />

Program Coordinator: Lisa Brooks, (212) 746-2218<br />

Duration <strong>of</strong> Training: 1 year<br />

Number <strong>of</strong> Positions: 3<br />

2010–2011 Fellows<br />

Babak Hassid, MD<br />

North Shore University Hospital<br />

Luke Kim, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Apurva Motivala, MD<br />

Sinai-Grace Hospital, Wayne State University<br />

Endocrinology, Diabetes and Metabolism<br />

This program is a comprehensive two-year training program<br />

that provides unique, in-depth clinical and academic experience<br />

in the field <strong>of</strong> endocrinology. Endocrine fellows receive a wide<br />

range <strong>of</strong> didactic instruction and clinical training in the inpatient<br />

and ambulatory facilities <strong>of</strong> three premier medical institutions:<br />

NewYork-Presbyterian Hospital, Memorial Sloan-Kettering Cancer<br />

Center and the Hospital for Special Surgery. The first year <strong>of</strong> the<br />

fellowship focuses on intensive clinical training, while the second<br />

year emphasizes clinical, translational or basic research. Fellows<br />

2010–2011 Fellows<br />

Peter Dahl, MD<br />

North Shore University Hospital, NYU School <strong>of</strong> <strong>Medicine</strong><br />

Jonathan Hugo, MD<br />

Barnes-Jewish Hospital, Washington University School <strong>of</strong> <strong>Medicine</strong>,<br />

St. Louis<br />

Rekha Kumar, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Vivien Leung, MD<br />

Montefiore Medical Center<br />

Gastroenterology and Hepatology<br />

This three-year program attracts some <strong>of</strong> the best and brightest<br />

trainees who are interested in pursuing a career in academic<br />

gastroenterology and hepatology. Currently, two fellows are<br />

accepted into the program annually. The first year is largely<br />

consultative, and fellows maintain a weekly ambulatory patient<br />

practice. Second-year fellows are expected to be involved in basic<br />

or clinical research. Third-year fellows continue the research projects<br />

developed in their second year, and have an opportunity to pursue<br />

specific areas <strong>of</strong> interest in inflammatory bowel disease, hepatology,<br />

liver transplantation and cancer screening and prevention. Over the<br />

course <strong>of</strong> their training, fellows generally perform more than 600<br />

upper endoscopies, 300 colonoscopies and a significant number<br />

<strong>of</strong> EUSs (endoscopic ultrasound) and ERCPs (endoscopic retrograde<br />

cholangio pancratography).<br />

Program Director: Brian Bosworth, MD<br />

Program Coordinator: Ming Su, (646) 962-4700<br />

Duration <strong>of</strong> Training: 3 years<br />

Number <strong>of</strong> Positions: 7<br />

2010–2011 Fellows<br />

Richard Blatt, MD<br />

Emory University School <strong>of</strong> <strong>Medicine</strong><br />

Arun Jesudian, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

AnnMarie Liapakis, MD<br />

Mount Sinai Medical Center<br />

Yasmin Metz, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Manan Shah, MD<br />

Beth Israel Deaconess Medical Center<br />

Subha Sundararajan, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Geriatric <strong>Medicine</strong><br />

This comprehensive fellowship program integrates outstanding,<br />

nationally recognized academic and clinical resources with the<br />

goal <strong>of</strong> training future clinical and academic leaders in geriatric<br />

medicine. Clinical training occurs in all appropriate geriatric<br />

settings: acute hospitals, long-term care facilities, patients’ homes,<br />

hospices, continuing care communities and ambulatory clinics. The<br />

second year <strong>of</strong> training focuses on completing an independent<br />

research project. Fellows can participate in a third year <strong>of</strong> training<br />

as clinician-researchers or clinician-educators through our Hartford<br />

Center <strong>of</strong> Excellence. One-year fellowship positions also become<br />

available from time to time for those unable to do the second year.<br />

Board certification can be obtained after completing a one-year<br />

fellowship.<br />

Program Director: Barrie Raik, MD<br />

Program Coordinator: David Aronson, (212) 746-3539<br />

Duration <strong>of</strong> Training: 2 years<br />

Number <strong>of</strong> Positions: 2 each year, total 4<br />

Ne Win, MD<br />

Memorial University Medical Center<br />

Patricia Wu, MD<br />

Saint Luke’s-Roosevelt Hospital Center<br />

Health Services Research<br />

Dr. James Hollenberg (L) with<br />

fellow in training.<br />

The goal <strong>of</strong> the T32 fellowship training program funded by the<br />

Agency for Healthcare Research and Quality is to train postresidency<br />

physicians to conduct interdisciplinary health services research.<br />

The objective is to train new physician-investigators to become<br />

independent researchers, using methodologically rigorous<br />

approaches to meet emerging health services research priorities:<br />

specifically, improving the effectiveness and outcomes <strong>of</strong> clinical<br />

practice, improving our ability to provide high-quality, cost-effective<br />

care and assessing the effectiveness <strong>of</strong> health systems changes<br />

on outcomes, quality, cost and access to healthcare. The program<br />

emphasizes theoretical, methodological and practice foundations in<br />

health services research, clinical research and behavioral sciences to<br />

enable physician-investigators to conduct research that will improve<br />

practice. A special emphasis <strong>of</strong> the program is to train researchers<br />

from diverse backgrounds so that they will have the skills to address<br />

the health problems and challenges faced by minority populations<br />

in our unique urban environment. Graduates from our program are<br />

principal or co-principal investigators on 110 grants totaling more<br />

than $47 million.<br />

2010–2011 Fellows<br />

Program Director: Mary E. Charlson, MD<br />

Administrator <strong>of</strong> Educational Programs: Alison Kenny,<br />

Melissa Rosen, MD<br />

Lina Fellizar, MD<br />

(212) 746-1608<br />

Mount Sinai Medical Center<br />

Saint Peter’s University Hospital<br />

Duration <strong>of</strong> Training: 2 years<br />

Tzivia Moreen, MD<br />

Number <strong>of</strong> Positions: Number varies<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

110 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 111


2010 Graduate Medical Education continued<br />

2010–11 Fellows<br />

Jennifer Downs, MD<br />

Columbia University College <strong>of</strong> Physicians and Surgeons<br />

Regina Jacob, MD<br />

Temple University Hospital<br />

Lisa Moreno, MD<br />

Schneider Children’s Hospital<br />

Kristine Olson, MD<br />

Yale University School <strong>of</strong> <strong>Medicine</strong><br />

Mihir Patel, MD<br />

Jefferson Medical College, Thomas Jefferson University<br />

Stephen Williams, MD<br />

Mount Sinai Medical Center<br />

Hematology and Medical Oncology<br />

This three-year fellowship consistently attracts outstanding<br />

fellows from a large national pool. A majority <strong>of</strong> the first year<br />

is spent on monthly rotations at various clinical services <strong>of</strong> the<br />

NewYork-Presbyterian Hospital/<strong>Weill</strong> <strong>Cornell</strong> Medical Center.<br />

The second year consists mostly <strong>of</strong> supervised laboratory and/<br />

or clinical research. The third year allows fellows to consolidate<br />

their educational experiences in diagnosis and management<br />

<strong>of</strong> hematologic/neoplastic disorders, and to continue research<br />

training.<br />

Program Director: Ronald Scheff, MD<br />

Program Coordinator: Karen Goldfarb, (212) 746-2061<br />

Duration <strong>of</strong> Training: 3 years<br />

Number <strong>of</strong> Positions: 18<br />

2010–2011 Fellows<br />

Paul Basciano, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Himisha Beltran, MD<br />

Hospital <strong>of</strong> the University <strong>of</strong> Pennsylvania<br />

Karen-Sue Carlson, MD, PhD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

John Chapin, MD<br />

Montefiore Medical Center<br />

Francine Garrett-Bakelman, MD, PhD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Sarika Jain, MD<br />

University <strong>of</strong> Michigan Health System<br />

Christopher Keir, MD<br />

Tufts New England Medical Center<br />

Emil Kuriakose, MD<br />

University <strong>of</strong> Texas Southwestern Medical Center at Dallas<br />

Ewelina Morawa, MD<br />

Advocate Lutheran General Hospital<br />

Adriana Rossi, MD<br />

Thomas Jefferson University Hospital<br />

Ashish Saxena, MD/PhD<br />

Montefiore Medical Center<br />

Yazl Zack, MD<br />

Montefiore Medical Center<br />

Infectious Diseases<br />

Designed to foster clinical and academic excellence, this fellowship<br />

program provides individualized training through faculty guidance,<br />

clinical rotations, mentored research and didactic course work.<br />

Graduates <strong>of</strong> the program are highly qualified for the practice <strong>of</strong><br />

infectious diseases medicine, bench and clinical research, and for<br />

leadership roles in medicine. The minimum fellowship duration is<br />

two years (ACGME-required); however, most fellows complete three<br />

years <strong>of</strong> training. Inpatient and ambulatory care are emphasized<br />

during the first year. The second and third years <strong>of</strong> fellowship<br />

emphasize clinical and basic laboratory research both at home<br />

and abroad in Haiti, Brazil, Ghana and Tanzania. In addition,<br />

fellows have the opportunity to pursue master’s degrees in clinical<br />

epidemiology and clinical investigation at <strong>Weill</strong> <strong>Cornell</strong>.<br />

Program Director: Kristen Marks, MD<br />

Program Coordinator: Leyla Pistone, (212) 746-7587<br />

Duration <strong>of</strong> Training: 2 years<br />

Number <strong>of</strong> Positions: 6<br />

2010–2011 Fellows<br />

Kathryn Dupnik, MD<br />

NewYork-Presbyterian Hospital (Columbia Campus)<br />

Samantha Jacobs, MD<br />

Mount Sinai Medical Center<br />

Jyoti Mathad, MD<br />

University <strong>of</strong> Maryland Medical Center<br />

Daniel Shirley, MD<br />

University <strong>of</strong> Colorado Health Sciences Center<br />

Matthew Simon, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Nephrology and Hypertension<br />

Nephrology and Hypertension fellows receive clinical training to<br />

treat patients with complicated acid-base and fluid and electrolyte<br />

problems, hypertension, acute and chronic kidney diseases and<br />

renal failure requiring replacement therapy with dialysis and<br />

kidney transplantation. Our fellows benefit from the vast clinical<br />

and research resources <strong>of</strong> NewYork-Presbyterian Hospital, <strong>Weill</strong><br />

<strong>Cornell</strong> Medical College, Rogosin Kidney Center and Memorial<br />

Sloan-Kettering Cancer Center. Fellows undertake a minimum <strong>of</strong> six<br />

months <strong>of</strong> dedicated elective time in clinical or bench research.<br />

Program Director: Phyllis August, MD<br />

Program Coordinator: Frances Gillen, (212) 746-0822<br />

Duration <strong>of</strong> Training: 2 years<br />

Number <strong>of</strong> Positions: 8<br />

2010–11 Fellows<br />

Minhson Bui, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Stanley Crittenden, MD<br />

The University <strong>of</strong> Chicago Medical Center<br />

David Epstein, MD<br />

Rhodes Island Hospital/Miriam Hospital/Brown University<br />

Medical School<br />

Sumie Iwasaki, MD<br />

NewYork-Presbyterian Hospital (Columbia Campus)<br />

John Lee, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Neil Manek, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Pallavi Patri, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Sharad Sathyan, MD<br />

University <strong>of</strong> Connecticut Health Center<br />

Pulmonary and Critical Care <strong>Medicine</strong><br />

This three-year training program <strong>of</strong>fers a structured curriculum<br />

encompassing rotations in the medical and surgical intensive<br />

care units, as well as the opportunity to care for inpatients and<br />

outpatients under the supervision <strong>of</strong> the division’s renowned<br />

clinical faculty. All fellows participate in 18 months <strong>of</strong> clinical or<br />

bench research in ongoing studies that include gene therapy for a<br />

variety <strong>of</strong> human diseases such as cystic fibrosis, lung cancer and<br />

cardiovascular disease.<br />

Program Director: Ronald G. Crystal, MD<br />

Program Coordinator: Diane Hawkins, (212) 746-2908<br />

Duration <strong>of</strong> Training: 3 years<br />

Number <strong>of</strong> Positions: 15<br />

2010–11 Fellows<br />

Anees F. Afroze, MBBS<br />

University <strong>of</strong> Oklahoma Medical Center<br />

Brendan Carolan, MBBch<br />

Mater Miseriocordiae University Hospital<br />

Sanjay Dhar, MBBS<br />

Lincoln Medical and Mental Health Center/Mount Sinai Medical<br />

Center<br />

Mary E. Harris, MD<br />

Montefiore Medical Center<br />

Ibrahim M. Hassan, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Justina M. Hessel, MD<br />

Montefiore Medical Center<br />

David H. Kung, MD<br />

Yale-New Haven Hospital<br />

Lindsay Lief, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Nida Qadir, MD<br />

NYU School <strong>of</strong> <strong>Medicine</strong><br />

Kapil K. Rajwani, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Eugene Shostak, MD<br />

Lahey Clinic Medical Center<br />

Rheumatology<br />

The Hospital for Special Surgery (HSS) rheumatology fellowship<br />

combines broad-based, in-depth clinical and research experiences<br />

to deliver superb training to medical pr<strong>of</strong>essionals. The clinical<br />

experience focuses on outpatient rheumatology clinics and<br />

inpatient Rheumatic Disease Unit (HSS), and inpatientconsultative<br />

services at NewYork-Presbyterian Hospital and Memorial Sloan-<br />

Kettering Cancer Center. In addition, fellows have access to clinics<br />

in <strong>of</strong>fice-based orthopedics and other musculoskeletal areas<br />

(osteoporosis, neuromuscular disease, radiology and rehabilitation).<br />

They also participate in divisional research advancing knowledge in<br />

the basic and clinical sciences.<br />

Program Director: Anne R. Bass, MD<br />

Program Coordinator: Janine Fernandez, (212) 774-2189<br />

Duration <strong>of</strong> Training: 3 years<br />

Number <strong>of</strong> Positions: 6<br />

2010–11 Fellows<br />

Elana Bernstein, MD<br />

Massachusetts General Hospital<br />

Soumya Chakravarty, MD, PhD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Lindsy Forbess, MD<br />

NewYork-Presbyterian Hospital (Columbia Campus)<br />

Beverly Johnson, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Susan Kim, MD<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Alana Levine, MD<br />

Selin Somersan, MD<br />

Igor Z. Barjaktarevic, MD, MSc<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

NewYork-Presbyterian Hospital (<strong>Weill</strong> <strong>Cornell</strong> Campus)<br />

Cabrini Medical Center (Mount Sinai SOM/New York University)<br />

112 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 113


Educational Opportunities<br />

in Global Health<br />

The Center for Globwal Health has long-standing research and training programs in Brazil, Haiti and Tanzania.<br />

In 2010, more than 70 students, residents and faculty members participated in programs at one <strong>of</strong> these<br />

<strong>Weill</strong> <strong>Cornell</strong> sites. Participants have an extraordinary opportunity to work with an outstanding cadre <strong>of</strong><br />

international investigators, deepening their knowledge <strong>of</strong> medicine from a global perspective.<br />

Haiti<br />

Nearly 30 years ago, a team from <strong>Weill</strong> <strong>Cornell</strong><br />

was instrumental in the formation <strong>of</strong> GHESKIO:<br />

Groupe Haitien d’Etude du Sarcome de Kaposi et<br />

des Infections Opportunistes (the Haitian Group for<br />

the Study <strong>of</strong> Kaposi’s Sarcoma and Opportunistic<br />

Infections). Significant support from the National<br />

Institutes <strong>of</strong> Health has enabled <strong>Weill</strong> <strong>Cornell</strong> and<br />

GHESKIO to produce more than 100 publications,<br />

including the first detailed description <strong>of</strong> AIDS in<br />

a developing country (The New England Journal<br />

<strong>of</strong> <strong>Medicine</strong>, 1983). In addition to the established<br />

AIDS program, <strong>Weill</strong> <strong>Cornell</strong>-GHESKIO provides<br />

STD and tuberculosis screening and treatment,<br />

as well as family planning, health education and<br />

counseling programs to more than 125,000 people<br />

each year. <strong>Weill</strong> <strong>Cornell</strong>-GHESKIO also conducts<br />

NIH-sponsored clinical trials for HIV vaccines and<br />

antiretroviral therapy. The success <strong>of</strong> this program is<br />

due in large measure to the leadership <strong>of</strong> Dr. Jean<br />

W. Pape, Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong>, and Dr. Warren<br />

D. Johnson, Jr., the B.H. Kean Pr<strong>of</strong>essor <strong>of</strong> Tropical<br />

<strong>Medicine</strong>. In 2010, The GHESKIO Center won<br />

the Gates Award for Global Health as the most<br />

outstanding global health institution in the world.<br />

Brazil<br />

This year marks the 47th anniversary <strong>of</strong> the<br />

collaboration between <strong>Cornell</strong> University and the<br />

Federal University <strong>of</strong> Bahia. Still growing after four<br />

decades, with partners in Natal, Fortaleza, Rio and<br />

the Fiocruz, the <strong>Cornell</strong>-Bahia program may be the<br />

longest-running collaboration <strong>of</strong> its type in the world.<br />

To date, more than 20 <strong>Cornell</strong> faculty members and<br />

100 students and fellows have participated in the<br />

program, and more than 250 peer-reviewed journal<br />

articles have emerged from its research. The program<br />

has been funded by The Commonwealth Fund and<br />

The Rockefeller Foundation, and since 1979, by<br />

the NIH. Current NIH funding supports the Tropical<br />

<strong>Medicine</strong> Research Center and a leptospirosis research<br />

program in Salvador, Brazil.<br />

(L to R): Dr. Susan Briggs (Massachusetts<br />

General Hospital), Dr. Pape, Lt. Mullen,<br />

Dr. Deschamps<br />

Tanzania<br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College and NewYork-<br />

Presbyterian Hospital established a formal affiliation<br />

with Bugando in 2006 with support from Dean<br />

Antonio M. Gotto, Jr. and the Touch Foundation.<br />

Dr. Robert Peck is currently based in Tanzania to<br />

coordinate the educational exchange. Physicians<br />

from <strong>Weill</strong> <strong>Cornell</strong> provide hands-on training on<br />

the wards, while Tanzanian residents and faculty<br />

have the opportunity to train in New York. Faculty<br />

from both institutions work together on curriculum<br />

development. In 2010, 54 <strong>Weill</strong> <strong>Cornell</strong> clinical<br />

residents and faculty visited Bugando to teach in<br />

anatomy, internal medicine, neurology, obstetrics and<br />

gynecology, ophthalmology, pediatrics, physiology,<br />

psychiatry and surgery. Father Peter Le Jacq, MD,<br />

an alumnus <strong>of</strong> <strong>Weill</strong> <strong>Cornell</strong> and a Maryknoll priest,<br />

worked in Mwanza, Tanzania, between 1987 and<br />

1997 and helped to found the medical college at<br />

Bugando Medical Center. BMC is an 850-bed tertiarycare<br />

hospital serving a population <strong>of</strong> 12 million.<br />

The GHESKIO Center<br />

won the Gates Award<br />

for Global Health<br />

as the most outstanding<br />

global health institution<br />

in the world.<br />

114 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 115


Training in Tanzania:<br />

A Transforming Experience<br />

for Medical Students and Residents<br />

The art and science <strong>of</strong> practicing medicine in a resource-limited country presents unique challenges,<br />

not the least <strong>of</strong> which is witnessing death and dying on a regular basis. “We have a 20% inpatient<br />

mortality rate at Bugando Medical Center (BMC), and I think, by far, that this is the hardest part for<br />

medical students and residents to deal with during their training experience,” says Dr. Robert N. Peck.<br />

“The number one phrase I hear from medical students about their training at Bugando is: This has<br />

been a transforming, life-changing experience.”<br />

“It’s a shock for students to come to a place like<br />

this where they will see death on a day-to-day basis,<br />

where people die <strong>of</strong> what could be preventable<br />

disease. It is shocking and it should be shocking.<br />

It should be shocking because it is something that<br />

should not occur in this world. But I always tell them,<br />

this is part <strong>of</strong> the learning experience; this is part <strong>of</strong><br />

understanding medicine in Africa. The hope is that<br />

it will motivate them to try to do something about it<br />

– to try to make a difference.”<br />

As a medical student at Vanderbilt University,<br />

Dr. Peck made two separate visits to Haiti working<br />

on an HIV research project with Dr. Dan Fitzgerald<br />

at GHESKIO (Port-au-Prince) as well as another<br />

project involving an anthrax outbreak in the<br />

Artibonite Valley. During these medical school<br />

rotations, he met Drs. Warren Johnson, Jean Pape,<br />

and Dan Fitzgerald. By 2006, Drs. Johnson and<br />

Fitzgerald invited Dr. Peck to join them in Tanzania<br />

where, together, they would forge a new vision –<br />

to create a bona fide medical school at Bugando.<br />

“It all started with Fr. Doctor Peter LeJacq and the<br />

Touch Foundation as part <strong>of</strong> a larger fundraising<br />

effort,” explains Dr. Peck. “A growing number <strong>of</strong><br />

medical students in Bugando needed faculty support<br />

and assistance with developing a curriculum. They<br />

went to Father LeJacq and asked if he could help<br />

them get <strong>Weill</strong> <strong>Cornell</strong> involved.”<br />

Dr. Peck and his wife, Elizabeth, a nurse<br />

practitioner, visited Tanzania and “fell in love with the<br />

place.” In 2007, they packed their bags, along and,<br />

along with their two children, moved to Tanzania.<br />

Since then, they have had another child, a daughter<br />

named Amani, meaning “peace” in Swahili.<br />

Dr. Peck arrived in Tanzania directly from completing<br />

his residency training at Massachusetts General<br />

Hospital, and set to work on two primary goals: one,<br />

to develop an outstanding curriculum to educate<br />

medical students and residents; two, to coordinate<br />

various collaborations for visiting residents, which<br />

numbered 30 to 40 per year, a large number<br />

even in the beginning years. Many wide-ranging<br />

interdepartmental collaborations exist at Bugando<br />

today, including neurosurgery, pediatrics, psychiatry,<br />

Dr. Robert Peck with his wife,<br />

Elizabeth, and children (L to<br />

R) Amani (baby), Jack (above),<br />

Bridget.<br />

116 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

Annual Report 2011 117


<strong>Weill</strong> Bugando is affiliated<br />

with Bugando Medical<br />

Centre, a 900-bed referral<br />

hospital dedicated to<br />

providing compassionate<br />

and equitable patient care<br />

to alleviate suffering in the<br />

Mwanza region.<br />

ophthalmology, nephrology, radiology, nursing, and<br />

pharmacology. There is also a Master’s in Public<br />

Health program and training available in Problem<br />

Based Learning (Dr. Mary Charlson’s course in<br />

epidemiology). Over time, more funds were raised to<br />

ensure that Bugando residents and faculty can travel<br />

to <strong>Weill</strong> <strong>Cornell</strong> in New York City for rotations.<br />

A massively growing number <strong>of</strong> medical students<br />

Not only have programs and collaborations grown,<br />

but the number <strong>of</strong> Tanzanian medical students<br />

has increased exponentially. The stats speak for<br />

themselves. In 2004, there were 10 medical students<br />

in Bugando. By 2009, 145. “We are now part <strong>of</strong><br />

a larger dynamic collaboration that I think could<br />

make Bugando one <strong>of</strong> the very best medical schools<br />

in East Africa,” says Dr. Peck.<br />

Crystal North, Resident - <strong>Medicine</strong><br />

Dr. David Skorton, President <strong>of</strong> <strong>Cornell</strong> University,<br />

visited Bugando Medical Center for four days.<br />

“It was fantastic for the students,” Dr. Peck said.<br />

“Dr. Skorton visited with hospital administration,<br />

came on rounds, met with students and residents<br />

to get their feedback, and spent time working in<br />

the hospital. He realized that the students needed<br />

basic text books on medicine, so he made a personal<br />

donation to make sure that medical students have<br />

the basic text books they need.”<br />

As Dr. Peck points out, nothing replaces hands-on<br />

learning, and the students at Bugando are learning<br />

from a plethora <strong>of</strong> divergent patient cases. A referral<br />

hospital for the entire western third <strong>of</strong> Tanzania,<br />

some 12 million people, Bugando receives many<br />

patients through its emergency room who are<br />

then admitted to wards consisting <strong>of</strong> 900 beds.<br />

In medicine alone, there is an average <strong>of</strong> 400<br />

admissions per month, the most common diagnosis<br />

being HIV-AIDS. Dr. Peck lists the other most common<br />

diagnoses in descending order: malaria; hypertension<br />

(e.g. stroke and heart disease); heart failure; and<br />

schistosomiasis (a waterborne disease).<br />

“Our medical students are seeing a very wide<br />

range <strong>of</strong> problems – including the diseases <strong>of</strong> the<br />

West. They need to know everything. As well as<br />

learning about all tropical diseases and diseases that<br />

we think <strong>of</strong> as being poverty-related diseases, they<br />

are seeing diseases <strong>of</strong> the West such as hypertension,<br />

stroke, diabetes, cardiovascular disease, and obesity.<br />

These are becoming epidemic, especially in the cities.<br />

So we’re now seeing the ‘diseases <strong>of</strong> affluence’<br />

moving into the cities.”<br />

For Dr. Peck, teaching at Bugando has brought<br />

an unexpected bonus. “What’s really interesting and<br />

fun for me is the reconnecting with patients. Before<br />

coming to Tanzania, typically I would work at my<br />

desk and enter information about the patient into<br />

my computer. But here I’m reminded that we’re more<br />

than medical clerks. I am interacting with patients<br />

at their bedside all the time. Despite the horrible<br />

deficits around them, in general, Tanzanians are kind,<br />

generous, good people. It’s a matter <strong>of</strong> seeing how<br />

the rest <strong>of</strong> the world lives and dies – which can be<br />

both tragic and inspiring.”<br />

Dr. Peck is a Lecturer, <strong>Weill</strong> Bugando University College <strong>of</strong><br />

Health Sciences; a Consultant, Bugando Medical Center; and<br />

an Assistant Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> and Assistant Pr<strong>of</strong>essor <strong>of</strong><br />

Pediatrics, WCMC.<br />

A large part <strong>of</strong> my decision to come to <strong>Weill</strong> <strong>Cornell</strong> for residency was an established connection with an<br />

international hospital. I anticipated my trip to Tanzania since I was an intern; the experience did not disappoint.<br />

The best piece <strong>of</strong> advice I received prior to leaving for Tanzania was to spend the first week simply standing back<br />

and observing. I was told to watch how the residents think about disease and management, how they work<br />

patients up, how they interact with one another and with the rest <strong>of</strong> the staff, how Dr. Peck interacts with the<br />

residents. Dr. Peck is an amazing example <strong>of</strong> what it means to completely immerse oneself in a different culture,<br />

working within the confines <strong>of</strong> that culture to effect positive change. I saw an autopsy and was able to follow<br />

it through to the histologic diagnosis. I learned about the common medical problems that face the population<br />

in that region <strong>of</strong> Tanzania, and how they adapt to providing medical care in a setting where the optimum<br />

treatment is rarely available. I learned about patience.<br />

Alumni<br />

Then and Now<br />

John Oates, MD<br />

The <strong>Medicine</strong> faculty at NewYork-Presbyterian/<strong>Weill</strong> <strong>Cornell</strong> recruited and led an outstanding House Staff.<br />

A commitment to excellence in patient care ran deep among the Residents with whom I was privileged to<br />

work. Because these were the values <strong>of</strong> our close colleagues, they became indelible influences on how each<br />

<strong>of</strong> us later cared for our patients. Those <strong>of</strong> us who later became engaged in research found encouragement<br />

for scientific inquiry in the hospital’s environment. The residents were enthusiastic about advances in medical<br />

science, curiosity was valued, and the research <strong>of</strong> the faculty held an attraction for us. I was particularly<br />

inspired by the pioneering research <strong>of</strong> Dr. Barr and his colleagues at the Rockefeller Institute that identified<br />

high density lipoproteins as protective against coronary artery disease. During a lunch with Dr. Richard<br />

Silver in the Physicians Dining Room, he told me that he had fulfilled the then obligatory military service<br />

requirement by serving as a Clinical Associate at the Clinical Center, NIH. Learning <strong>of</strong> this opportunity opened<br />

an appealing option for me. When I told David Barr <strong>of</strong> my interest in the prospect <strong>of</strong> research training at the NIH, he immediately<br />

picked up his telephone and made it happen. The <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> was like a family for my wife, Meredith, and me.<br />

Dr. John A. Oates received his MD degree from Wake Forest University and was a resident in medicine and cardiology at the<br />

New York Hospital-<strong>Cornell</strong> Medical Center. At the NIH (Clinical Center), he was a Clinical Associate and Senior Investigator<br />

prior to joining the faculty <strong>of</strong> the Vanderbilt University School <strong>of</strong> <strong>Medicine</strong> where he founded the Hypertension and Clinical<br />

Pharmacology programs. He was Chair <strong>of</strong> Vanderbilt University’s <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> from 1983 to 1997 and is the Thomas<br />

F. Frist, Sr. Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> and Pr<strong>of</strong>essor <strong>of</strong> Pharmacology. Dr. Oates has been elected to the Institute <strong>of</strong> <strong>Medicine</strong> <strong>of</strong> the<br />

National Academy <strong>of</strong> Sciences, the American Academy <strong>of</strong> Arts and Sciences, and to Fellowship in the American Association<br />

for the Advancement <strong>of</strong> Science. He received the Excellence in Clinical Research Award from the NIH GCRC program, the Earl<br />

Sutherland Prize for Research from Vanderbilt University, the Novartis Award from the Council on High Blood Pressure Research<br />

<strong>of</strong> the American Heart Association and the Award <strong>of</strong> Merit from the American Heart Association.<br />

Robert M. Carey, MD<br />

Residency in medicine at The New York Hospital-<strong>Cornell</strong> Medical Center was an exciting period <strong>of</strong> personal<br />

and pr<strong>of</strong>essional growth for me. The diverse patient population was truly an exceptional base from which<br />

to learn. I was inspired by outstanding faculty members, such as Aaron Feder, Jerry Barondess, Tom Killip,<br />

Carl Muschenheim, Ed Hook, Ralph Nachman and many others, who were role models for the best in patient care<br />

and teaching. Exposure to such great chief residents as Harvey Klein and Chuck Steinberg was also important in<br />

my learning and maturation as a clinician. The <strong>Cornell</strong> experience stimulated me to enter subspecialty fellowship<br />

and pursue a career in academic medicine. Indeed, <strong>Cornell</strong> provided me with outstanding medical training and<br />

leadership skills for success. I will be forever grateful to <strong>Cornell</strong> for such an outstanding residency experience.<br />

Dr. Carey is David A. Harrison III Distinguished Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong>; Dean, Emeritus; and University Pr<strong>of</strong>essor<br />

at the University <strong>of</strong> Virginia. He is one <strong>of</strong> the world’s foremost endocrinologists, specializing in cardiovascular<br />

endocrinology and hypertension. After leaving <strong>Cornell</strong>, Dr. Carey completed fellowships in<br />

endocrinology at Vanderbilt and in hypertension at the University <strong>of</strong> London in England. At the<br />

University <strong>of</strong> Virginia, Dr. Carey was Head <strong>of</strong> the Division <strong>of</strong> Endocrinology and Metabolism (1978-86)<br />

and Dean <strong>of</strong> the School <strong>of</strong> <strong>Medicine</strong> (1986-2002). He has received over 35 years <strong>of</strong> continuous<br />

funding for research from the National Institutes <strong>of</strong> Health. He has been President <strong>of</strong> The Endocrine<br />

Society and <strong>of</strong> the American Clinical and Climatological Association and Chair <strong>of</strong> the Council for<br />

High Blood Pressure Research <strong>of</strong> the American Heart Association. Dr. Carey has received the Thomas<br />

Jefferson Award <strong>of</strong> the University <strong>of</strong> Virginia, the Distinguished Physician Award <strong>of</strong> The Endocrine<br />

Society, the Irvine Page-Alva Bradley Lifetime Achievement Award <strong>of</strong> the Council for High Blood<br />

Pressure Research, the Distinguished Achievement Award <strong>of</strong> the American Heart Association and<br />

the Robert Tigerstedt Distinguished Scientist Award <strong>of</strong> the American Society <strong>of</strong> Hypertension.<br />

118 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 119


Alumni Then and Now continued<br />

Financial Report<br />

and Donors<br />

Gerald L. Mandell, MD<br />

I am very privileged to have had the opportunity to be a six-times Cornelian (undergraduate, medical<br />

school, internship, residency, fellowship and instructor). My time in Ithaca and at The Medical College<br />

was instrumental in focusing my goals on a career in academic medicine. <strong>Cornell</strong> Medical College was<br />

great! The basic science pr<strong>of</strong>essors and the clinical faculty taught and inspired me. My classmates were<br />

superstars from all over the country with varied backgrounds and career interests. I was enthralled by<br />

the program in the <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> and elected to take all <strong>of</strong> my postgraduate training there.<br />

My experiences as an intern and resident (on duty every other night!) were exceptional. I finally did<br />

forgive my wife for having our first son (a <strong>Weill</strong> <strong>Cornell</strong> MD, PhD) on my internship night <strong>of</strong>f so I was<br />

up working three days in a row. Patients, from the very ill with common diagnoses to “fascinomas”<br />

with obscure conditions, came from all over to “the Mecca.” My fellow house <strong>of</strong>ficers were a pleasure<br />

to work with. We really were a team. The clinical faculty and the full time faculty were wonderful<br />

teachers and role models. When family or friends needed to see a physician – there was no question –<br />

NewYork-<strong>Cornell</strong> was the place to be. One <strong>of</strong> the legends illustrating the excellence <strong>of</strong> the department<br />

was that a former Chair <strong>of</strong> <strong>Medicine</strong> could tell how many people were in a room by percussing the<br />

closed door.<br />

Infectious disease appealed to me because <strong>of</strong> the breadth <strong>of</strong> the conditions, and it meshed nicely<br />

with my research interest in polymorphonuclear neutrophils. After completing my fellowship in<br />

Infectious Diseases at <strong>Cornell</strong>, Dr. Edward Hook, who was the chief <strong>of</strong> the division and my hero and<br />

mentor, invited me to join him at his new position as Chair, <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong>, University <strong>of</strong><br />

Virginia. That was 41 years ago.<br />

Dr. Mandell is a Phi Beta Kappa honors graduate <strong>of</strong> <strong>Cornell</strong> University and an AOA graduate<br />

<strong>of</strong> the Medical College. His many honors and awards include membership in ASCI and AAP, Master<br />

<strong>of</strong> the American College <strong>of</strong> Physicians, <strong>Weill</strong> <strong>Cornell</strong> Medical College Alumnus <strong>of</strong> Distinction, President<br />

<strong>of</strong> the Infectious Diseases Society <strong>of</strong> America (IDSA), receipt <strong>of</strong> their highest award – the Alexander<br />

Fleming award, the IDSA Feldman award, Council <strong>of</strong> the NIH for Infectious Diseases, Chair <strong>of</strong> the<br />

American Board <strong>of</strong> Internal <strong>Medicine</strong> section on Infectious Diseases, NIH merit award for research,<br />

Inventor <strong>of</strong> the Year at the University <strong>of</strong> Virginia. The University <strong>of</strong> Virginia<br />

established a chair in his name. Dr Mandell has authored more than<br />

300 scientific publications; served as President <strong>of</strong> the American Clinical<br />

and Climatologic Association; is founding editor <strong>of</strong> the leading Infectious<br />

Diseases book in the world, “Principles and Practice <strong>of</strong> Infectious<br />

Diseases”; and was elected to membership in the Institute <strong>of</strong> <strong>Medicine</strong><br />

<strong>of</strong> the National Academy <strong>of</strong> Sciences. At University <strong>of</strong> Virginia he is the<br />

emeritus Owen R. Cheatham Pr<strong>of</strong>essor <strong>of</strong> the Sciences, Chief <strong>of</strong> the<br />

Division <strong>of</strong> Infectious Disease and Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong>.<br />

120 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 121


2010 Financial Report<br />

Admissions<br />

16000<br />

7.5<br />

The DOM experienced financial growth in 2010. Total income and clinical revenue continued to increase,<br />

along with institutional overhead from funded research. Outpatient visit volume capped at 180,000<br />

15000<br />

7.25<br />

encounters, with Cardiology and Gastroenterology-Hepatology experiencing the most growth. Total<br />

admissions peaked at 15,000, while length <strong>of</strong> stay (LOS) increased slightly by less than 1%. While outpatient<br />

14000<br />

7.0<br />

encounters remain steady, our inpatient encounters increased 19.7% (85,924 to 102,811 encounters) that<br />

partly attributed to our increase in clinical revenue. Most <strong>of</strong> the inpatient increase is from our newly created<br />

13000<br />

6.75<br />

Division <strong>of</strong> Hospital <strong>Medicine</strong>.<br />

12000<br />

Admissions<br />

Average Length <strong>of</strong> Stay<br />

6.0<br />

Total Income<br />

(dollars in millions)<br />

Clinical Revenue<br />

(dollars in millions)<br />

Total Outpatient Visit Volume<br />

(thousands)<br />

Cardiology Outpatient Visit Volume<br />

(thousands)<br />

180<br />

100<br />

200<br />

20<br />

160<br />

75<br />

175<br />

15<br />

140<br />

50<br />

150<br />

10<br />

120<br />

25<br />

125<br />

5<br />

100<br />

2007 2008 2009 2010<br />

0<br />

2007 2008 2009 2010<br />

100<br />

2007 2008 2009 2010<br />

0<br />

2007 2008 2009 2010<br />

<strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Research<br />

Expenditures<br />

FY 2010<br />

Institutional Indirect Costs<br />

Generated by <strong>Medicine</strong><br />

(dollars in millions)<br />

Gastroenterology Outpatient<br />

Visit Volume<br />

(thousands)<br />

Hematology – Oncology Outpatient<br />

Visit Volume<br />

(thousands)<br />

Cardiology<br />

11.7<br />

Gastroenterology<br />

13.0<br />

12<br />

25<br />

50<br />

Hematology/<br />

Oncology<br />

28.5<br />

Nephrology &<br />

Hypertension<br />

7.3<br />

9<br />

20<br />

40<br />

Immunology<br />

5.7<br />

15<br />

30<br />

Geriatrics 6.3<br />

6<br />

Infectious Diseases 19.1<br />

GIM 4.7<br />

Pulmonary 1.0<br />

Endocrinology 2.6<br />

3<br />

10<br />

5<br />

20<br />

10<br />

0<br />

2007 2008 2009 2010<br />

0<br />

2007 2008 2009 2010<br />

0<br />

2007 2008 2009 2010<br />

Grants, Clinical Trials, Donations<br />

122 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> ■ Physician Organization<br />

Annual Report 2011 123


2010 Donors<br />

Fund for <strong>Medicine</strong><br />

The Fund for <strong>Medicine</strong> raises money<br />

to support critical resources and<br />

innovative programs in education,<br />

patient care and biomedical research<br />

at New York-Presbyterian Hospital<br />

and <strong>Weill</strong> <strong>Cornell</strong> Medical College.<br />

These resources and programs enable<br />

our physicians and scientists to carry<br />

on a long tradition <strong>of</strong> excellence in<br />

medicine with the ultimate goal in<br />

mind: to provide superior patient<br />

care to the communities they serve.<br />

Ms. Harriet Abramson<br />

Advanced Research Foundation, Inc.<br />

AIG Matching Grants Program<br />

Mr. and Mrs. Murray Alon<br />

The Applebaum Foundation<br />

Mrs. Patricia Balsamo<br />

Ms. Patricia A. Banks<br />

Ms. Rena Bartos<br />

Ms. Joan S. Beir<br />

The Beir Foundation<br />

Mr. Charles E. Binder<br />

Ms. Rita S. Brause<br />

Ms. Roberta C. Brause<br />

Ms. Karen Brenner<br />

Mr. Clyde Brownstone<br />

Mrs. Diane Brownstone<br />

Brownstone Family Foundation<br />

Mr. John B. Caddell, II<br />

Mrs. John L. Cady<br />

Mrs. Korda H. Caplan<br />

Carl and Fay Simons Donor<br />

Advised Fund<br />

The Charlene and David Howe<br />

Foundation<br />

Charles & Lucille King Family<br />

Foundation<br />

Mr. William R. Coleman<br />

Coleman Family Charitable Foundation<br />

Ms. Ann B. Copeland<br />

Ms. Marion Cowan-Loh<br />

D’Agostino Foundation<br />

Mr. Joseph R. Daly<br />

Ms. Shirley W. Della Vecchia<br />

Mr. Bruce Dorskind<br />

Mrs. Phyllis M. Feinert<br />

Mr. Robert E. Feldbaum<br />

Ms. Harriet Feldmann<br />

Mr. and Mrs. Richard Feldstein<br />

Feldstein Family Charitable Foundation<br />

Dr. Bernard T. Ferrari<br />

Ferrari Consultancy<br />

Fidelity Charitable Gift Fund<br />

Ms. Constance F. Fischer<br />

Friman & Stein, Inc.<br />

Mr. Henry Fruhauf<br />

Mr. Robert L. Gipson<br />

Mr. Marvin S. Gittes<br />

Mrs. Helene Gleeman<br />

The Grace R. and Alan D. Marcus<br />

Foundation<br />

Mr. John A. Griffin<br />

Ms. Arlene Solomon Haas Guerra<br />

Dr. and Mrs. Subhash C. Gulati<br />

Ms. Rose Haas<br />

The Harold and Mimi Steinberg<br />

Charitable Trust<br />

Dr. Barry J. Hartman<br />

Mr. Joel H<strong>of</strong>fman<br />

Mr. David S. Howe<br />

Mr. Henry H. Hoyt, Jr.<br />

Mrs. Mary O. Hughes<br />

Jerome and Laura Dorfman<br />

Charitable Foundation<br />

The Jewish Communal Fund<br />

The Joseph R. Daly Foundation<br />

Mrs. Leah I. Kantor<br />

Ms. Diana King<br />

Korda Herskovits Caplan<br />

Philanthropic Fund<br />

Ms. Joan Kron<br />

Lebensfeld Foundation<br />

Ms. Jacqueline S. Leeds<br />

Ms. Catherine P. May<br />

Ms. Barbara B. McGhie<br />

Mr. Robert B. Menschel<br />

Mr. and Mrs. Morris A. Mondschein<br />

The Murray Alon Charitable<br />

Foundation<br />

Oceanic Heritage Foundation<br />

Ambassador Herbert S. Okun<br />

Mr. Sabino S. Pace<br />

Mr. Creighton H. Peet<br />

Ms. Vita L. Pellettieri<br />

Mr. Andrew G. Pietrini<br />

Mr. Edward K. Portn<strong>of</strong><br />

Mr. and Mrs. Robert M. Poss<br />

Mr. Michael H. Ratner<br />

Mr. and Mrs. Richard Roob<br />

Mr. Arnold S. Root<br />

Dr. Howard Rosenberg<br />

Mrs. Aviva Rosenberg<br />

Dr. Benjamin A. Rosenberg<br />

Mr. Jack E. Rosenfeld<br />

Felice Rovelli<br />

Mr. Michael B. Sapik<br />

Mr. Ernest Schaal<br />

Mrs. Ernestyna Schenker<br />

Mr. Charles B. Selden<br />

Dr. Melvin R. Shevach<br />

Ms. Nancy G. Shor<br />

Ms. Helene Silverman<br />

Mr. Carl Simons<br />

Mr. Daniel Soba<br />

Mr. Arnold R. Sollar<br />

The Sollar Foundation, Inc.<br />

Mr. Robert Stein<br />

Mr. Mark Stitzer<br />

Mr. and Mrs. Fred C. Stoll<br />

Ms. Geraldine Stover<br />

The Tianaderrah Foundation<br />

Vital Projects Fund, Inc.<br />

Mrs. Bertha Weiser<br />

Mr. Warren A. Weiss<br />

Ms. Dana A. Weiss<br />

Ms. Marjorie Weller<br />

William T. Foley Foundation<br />

The Winston Foundation, Inc.<br />

Dr. James F. Wittmer<br />

Dr. David J. Wolf<br />

Mr. William D. Zabel<br />

Ms. Robin F. Zwerling<br />

Friends <strong>of</strong> the <strong>Department</strong><br />

The <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> is<br />

deeply grateful to the Friends <strong>of</strong><br />

<strong>Medicine</strong>. These individuals have<br />

generously contributed to furthering<br />

the department’s advances in<br />

patient care, education <strong>of</strong> physicianscientists,<br />

and bench-to-bedside<br />

breakthroughs in research. There are<br />

a large number <strong>of</strong> contributors, some<br />

1,350 former patients and friends,<br />

who have given donations below<br />

the level <strong>of</strong> $100. Due to space<br />

limitations, we cannot list these<br />

donors, but we express our sincerest<br />

thanks for their loyal support.<br />

72nd Street Medical Associates, P.C.<br />

A Taste <strong>of</strong> Honey, Inc.<br />

A.L. Murphree M.D., Inc.<br />

Mrs. Nancy C. Abbott<br />

Mr. Preston H. Abbott<br />

Ms. Judith Aberg<br />

Ms. Lynn R. Abraham<br />

Ms. Alice J. Abraham<br />

Mr. Robert Abramovitz<br />

Ms. Harriet Abramson<br />

ABTCC Developmental Studies<br />

<strong>Department</strong><br />

Accordia Global Health Foundation<br />

Ackerman Family Fund<br />

Dr. Alberto M. Acosta<br />

Mr. John M. Adams<br />

Ms. Lois Adelman<br />

Dr. Ronald Adelman<br />

Ms. Sherril Aden<br />

Ms. Ann Adenbaum<br />

Mrs. Mary Anne Adkins<br />

Adolph & Ruth Schnurmacher<br />

Foundation, Inc.<br />

Advanced Research Foundation, Inc.<br />

Ms. Rebecca Ahrens-Nicklas<br />

AIDS Celebrity Golf & Tennis Classic<br />

AIG Matching Grants Program<br />

Dr. John Aldous<br />

Mrs. Jeannette Aldous<br />

Ms. Gillian Aldred<br />

Dr. Hanna Alemayehu<br />

Mrs. Kim K. Alexander<br />

Ms. Sarah Alexander<br />

Ms. Annetta Alexandridis<br />

Mr. Stephen M. Alfieri<br />

Mr. Vincent Allegretti<br />

Mrs. Ethel S. Allen<br />

Ms. Esther Allen<br />

Ms. Margaret Allen<br />

Mr. and Mrs. Murray Alon<br />

Mr. Jerome Alpern<br />

Alpha Delta Phi at <strong>Cornell</strong>, Inc.<br />

Mr. Joseph Alsberge<br />

Ms. Kathryn Altman<br />

Ms. Resa Alvord<br />

Mr. William W. Ambrose<br />

American International Educators, Inc.<br />

American Society <strong>of</strong> Colon & Rectal<br />

Surgeons<br />

America’s Choice, Inc.<br />

Mrs. Donna B. Amico<br />

Ms. Susan Amighi<br />

Amir & Rosita Manocherian Family<br />

Foundation<br />

Mrs. Fran Amirsaleh<br />

Mr. Philip Ammirati<br />

Ms. Carol B. Amos<br />

Anchorage Charitable Fund<br />

Ms. Linn Anderson<br />

Mrs. Cynthia T. Anderson<br />

Mr. M. E. Anderson<br />

Mr. and Mrs. Alan M. Anderson<br />

Mr. Takeshi Ando<br />

Ms. Camille Andrews<br />

Andrews Kurth, LLP<br />

Ms. Julia Andrukonis<br />

Mr. Christopher C. Angell<br />

Angelo Donghia Foundation<br />

Anonymous<br />

Mr. Andrew Ansaldi<br />

Mr. Aaron Ansaldi<br />

Anil Antony<br />

The Applebaum Foundation<br />

Mr. Ryan Applegate<br />

Appleman Foundation, Inc.<br />

Mrs. Gwen S. Aquadro<br />

Shivaun D. Archer<br />

Mrs. Adamandia Arestou<br />

Ms. Severine Armand<br />

Mr. Paul D. Armstrong<br />

Ms. Mary L. Arnold<br />

Ms. Nydia Arocho<br />

Dr. Louis J. Aronne<br />

Mrs. Susan B. Arroyo<br />

Mr. Greg Arvesen<br />

The Asen Foundation<br />

Ms. Sara E. Asher<br />

Aubrey’s Inc.<br />

Ms. Justine E. Auchincloss<br />

Ms. Susan M. Aull<br />

Ms. Meredith J. Aull<br />

Avedis Zildjian Company<br />

Mr. Jesse Aversano<br />

Avian Securities<br />

B<br />

Mrs. Kathleen Babkow<br />

Dr. Sateesh C. Babu<br />

Ms. Melanie C. Bacon<br />

Mrs. Christine Bagin<br />

Mr. John Bai<br />

Mr. Mark Bailey<br />

Mr. Julian C. Baker<br />

Mr. Mike Baker<br />

Mrs. Andrea Baker<br />

Ms. Felicie R. Balay<br />

Mrs. Sallie Baldwin<br />

Ms. Martha Balladares<br />

Mr. Jeffrey Ballyns<br />

Mr. Arthur E. Balsamo, P.A.<br />

Mrs. Patricia Balsamo<br />

Dr. Heejung Bang<br />

Bank <strong>of</strong> America Foundation<br />

The Bank <strong>of</strong> Tokyo-Mitsubishi UFJ, Ltd.<br />

Ms. Nancy Banks<br />

Ms. Patricia A. Banks<br />

Mr. and Mrs. John Bannon<br />

Mr. Anthony N. Baratta<br />

Ms. Virginia P. Barber<br />

Mr. Brian Barber<br />

Dr. Jean T. Barbey<br />

Dr. and Mrs. Jack D. Barchas<br />

Mr. Michael Barclay<br />

Bard College<br />

Barkan Management Company, Inc.<br />

Ms. Janae Barker<br />

Mr. Edward L. Barlow<br />

Ms. Annette Barlow<br />

Mr. Gordon S. Barr<br />

Mr. and Mrs. Joseph P. Barreriro<br />

Ms. Leigh Barrett<br />

Mr. Jon Barrett<br />

Mr. Gregory Barton<br />

Mr. Dale Barton<br />

Ms. Mary Bartos<br />

Ms. Rena Bartos<br />

Yuliy Baryshnikov<br />

Mr. Thomas Bashore<br />

Ms. Barbara J. Bastow<br />

Dr. Paul M. Basuk<br />

Mrs. Elizabeth A. Bates<br />

Mr. Richard J. Bauer<br />

Beacon School<br />

Mr. Robert Bean<br />

Ms. Brenda Bear<br />

Joseph A. Beck, III<br />

Dr. David S. Becker<br />

Mr. Scott W. Becker<br />

Ms. Dotty Beckwith<br />

Becton Dickinson and Company<br />

Mr. Harry Beda<br />

Mr. Gerald A. Bednarski<br />

Ms. Wilfreda Behets<br />

Mr. Ruediger Behmel<br />

Ms. Joan S. Beir<br />

The Beir Foundation<br />

Ms. Lori K. Beizer<br />

Ms. Bonnie Belkin<br />

Mr. Christopher J. Bell<br />

Mr. Matthew G. Bell<br />

Mr. Sanford A. Bell<br />

Mr. Sergey Belomestnykh<br />

Mr. Noel Beninati<br />

Mr. John Bennett<br />

Mr. Richard A. Bennett<br />

Mrs. Leslie P. Bennison<br />

Mr. Julian M. Benscher<br />

Dr. Constance Benson<br />

Mr. Carter Bentley<br />

Ms. Kellie Bentz<br />

Dr. Ivan Bergstein<br />

Mr. Marc Berk<br />

Dr. Israel S. Berkowitz<br />

Ms. Linda Beth Berman<br />

Mr. Nicholas Berry<br />

Ms. Susanna L. Bertelsen<br />

Mrs. Linda Beynon<br />

Mr. Jaydeep Bhat<br />

Ms. Evelyn Bhumitra<br />

Dr. Celso Bianco<br />

Ms. Sheila Bienemann<br />

Ms. Tracey Biggers<br />

Mr. Charles E. Binder<br />

124 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 125


2010 Donors continued<br />

Ms. Marissa R. Bishop<br />

Blackbaud, Inc.<br />

Ms. Barbara Blackmond<br />

Mr. William M. Blair, Jr.<br />

Dr. James A. Blake<br />

Mr. Jason M. Blau<br />

Mr. Max Blekhter<br />

Ms. Heide-Marie Bliss<br />

Mr. James A. Block<br />

Mr. Jonathan Block<br />

Ms. Gilda Block<br />

Ms. Kathleen Blomquist<br />

Blue Hill Road Leshkowitz & Co.<br />

Ms. Lois D. Blumenfeld<br />

Dr. David S. Blumenthal<br />

Ms. Jasmin Blunck<br />

Ms. Marsha N. Boasso<br />

Ms. Anne Bodkin<br />

Mr. Leonard B. Boehner<br />

Mr. Elijah Bogart<br />

Mrs. Stefni Bogard<br />

Ms. Esther Bogin<br />

Dr. Jerome Bogin<br />

Ms. Eve S. Bogle<br />

Mr. Luc Bomans<br />

Ms. Trina Bombardier<br />

Ms. Kathryn Boor<br />

Mr. Michael Bopp<br />

Mr. Mark Borchert<br />

Dr. William B. Borden<br />

Mr. William Borden<br />

Mr. Joseph L. Boren<br />

Ms. Ghislaine Borno<br />

Ms. Beverly Bortner<br />

Mrs. Catherine C. Bosch<br />

Ms. Pamela Boschert<br />

Dr. George J. Bosl<br />

Boston Consulting Group, Inc.<br />

Dr. Susan B. Bostwick<br />

Dr. Brian P. Bosworth<br />

Ms. Olga Boudker<br />

Ms. Jennifer H. Bourdain<br />

Ms. Sharon Bovie<br />

Ms. Amelia A. Bower<br />

Mr. Steven Boxer<br />

Ms. Geraldine M. Boxer<br />

Mr. Haig J. Boyadjian<br />

Mr. Adam Boyd<br />

Mr. Lawrence C. Boyd<br />

Mr. William J. Boyd, Jr.<br />

Mrs. Constance E. Boyle<br />

Ms. Katharine Boyle<br />

Ms. Mary Boyle<br />

Bracewell & Giuliani, LLP<br />

Mrs. Marike J. Bradford-Toothaker<br />

The Braewold Fund<br />

Ms. Patsy Brannon<br />

Dr. Barry D. Brause<br />

Ms. Rita S. Brause<br />

Ms. Roberta C. Brause<br />

Ms. Karen Brenner<br />

Mr. Timothy F. Brewer<br />

Mr. Kenneth Bridbord<br />

Dr. Mary F. Bridge<br />

Ms. Susan Briggs<br />

Dr. David J. Brillon<br />

Mr. James Brinkley<br />

Bristol-Myers Squibb Company<br />

Mrs. Beverly U. Brodsky<br />

The Brooke Janis Living Trust<br />

Mr. Bart B. Brown<br />

Ms. Carole R. Brown<br />

Ms. Dolores Brown<br />

Mr. Luvaghn Brown<br />

Mrs. Marjorie W. Brown<br />

Ms. Nancy E. Brown<br />

Ms. Nancy L. Brown<br />

Ms. Sara H. Browne<br />

Ms. Marcy Brownson<br />

Mr.Clyde Brownstone<br />

Mrs. Diane Brownstone<br />

Brownstone Family Foundation<br />

Bruce A. Gimbel Foundation<br />

Ms. Karen Brummund<br />

Ms. Doris Bry<br />

Ms. Susan Buchanan<br />

Ms. Andrea Buffara<br />

Ms. Angela Buffenn<br />

Mr. William Buffie<br />

Ms. Jeannine M. Buono<br />

Mr. Harry J. Buonocore<br />

Ms. Jane Bupp<br />

Dr. Amelia L. Burgess<br />

Mr. William L. Burke<br />

Ms. Pamela Burks<br />

Burleson Research Technologies, Inc.<br />

Ms. Jeanette Busch<br />

Dr. James B. Bussel<br />

Mr. Victor Bustos<br />

Mrs. Carol L. Butler<br />

Ms. Margaret Butler<br />

Ms. Kathy Byrnes<br />

Ms. Robin Byrt<br />

C<br />

Mr. John B. Caddell, II<br />

Mr. Oliver Cadogan<br />

Mrs. John L. Cady<br />

Ms. Joanna Cahill<br />

Mr. Charles C. Cahn, Jr.<br />

Ms. Nancy S. Calcagnini<br />

Ms. Bettie Caldwell<br />

Mr. Carl C. Caldwell<br />

Mr. Joseph P. Califano<br />

Mr. Jeremiah M. Callaghan<br />

Mr. Edward W. Callahan<br />

Calliope and Manuel Kulukundis<br />

Foundation<br />

Mr. Nicholas Cambas<br />

Mrs. Denise Camilleri<br />

Mr. Chris Campos<br />

Cancer Research and Treatment<br />

Fund, Inc.<br />

Capital Care Medical Group, LLC<br />

Mrs. Korda H. Caplan<br />

Mr. Bernard C. Caplan<br />

Mr. Daniel Capps<br />

Ms. Joyce Capuano<br />

Cardillo & Corbett<br />

Cardiology Consultants <strong>of</strong> NY, PC<br />

Cardiology Consultants <strong>of</strong> Philadelphia<br />

Cardionet, Inc.<br />

Carl and Fay Simons Donor Advised<br />

Fund<br />

Mr. Paul V. Carlucci<br />

Mr. Kenneth Carmel<br />

Ms. Dianne V. Carnegie<br />

Carolina Digestive Health Associates<br />

Carolina Wholesale Office Machine<br />

Company, Inc.<br />

Mr. Curt C. Carpenter<br />

Ms. Angela Carpenter<br />

Ms. Amanda Carreiro<br />

Ms. Lois Carroll<br />

Mr. Jay W. Carter<br />

Ms. Dorothy A. Carter<br />

Mr. Marvelle B. Carter<br />

Ms. Constance B. Cartwright<br />

Cary L. Guy Foundation<br />

Dr. Mario B. Castillo<br />

Celgene Corporation<br />

Central Park Boat House, LLC<br />

Mr. and Mrs. Clive Chajet<br />

Mr. Kevin Chang<br />

The Charlene and David Howe<br />

Foundation<br />

Charles & Lucille King Family<br />

Foundation<br />

Charles and Mildred Schnurmacher<br />

Foundation, Inc.<br />

Charles Hertzig Foundation<br />

Kuei-Chiu Chen<br />

Dr. Adam Cheriff<br />

Cheryl A. Gallant, Inc.<br />

Children’s Hospital <strong>of</strong> Los Angeles<br />

Mr. Russell Chin<br />

Chios Navigation (Hellas) Ltd.<br />

Dr. Hearn J. Cho<br />

Dr. Sunghee Cho<br />

Ms. Lubna Choudhury<br />

Mrs. Carole A. Christensen<br />

Dr. Charles L. Christian<br />

Ms. Marian Christie<br />

Ms. Anne M. Christner<br />

Dr. James P. Christodoulou<br />

Dr. Edmond K. Chu<br />

Ms. Laura Chunos<strong>of</strong>f<br />

Dr. Amy E. Chused<br />

Ms. Brenda Cialone<br />

Mr. Salvatore Cilmi<br />

Ms. Marilynn D. Civic<br />

Claire & Meyer Frank and Leann<br />

Frank Charitable Foundation, Inc.<br />

Mr. David Clapp<br />

Nancy Clapp-Channing<br />

Clarfeld Financial Advisors, Inc.<br />

Mr. Gerald Clark<br />

Mr. James M. Clawson<br />

Ms. Kathleen Cochrane<br />

Mr. Edmund C<strong>of</strong>fin<br />

Mr. John D. C<strong>of</strong>fin<br />

Mr. William Coggin<br />

Mr. Joel I. Cohen<br />

Mr. Richard N. Cohen<br />

Dr. Richard P. Cohen<br />

Cohen Hacker Rothstein & Pearl, LLC<br />

Dr. Symra A. Cohn<br />

Dr. Susan E. Cohn<br />

Dr. Curtis L. Cole<br />

Mrs. Allison H. Coleman<br />

Dr. Morton Coleman<br />

Mr. William R. Coleman<br />

Coleman Family Charitable Foundation<br />

Coles Family Foundation<br />

Ms. Anne Coletti<br />

Ms. Ann Collier<br />

Mrs. Anne B. Collins<br />

Dr. Pamela Y. Collins<br />

Mr. Richard J. Collins<br />

Ms. Hilda Collins<br />

Ms. Eileen Collins<br />

Mrs. Joanne Colon<br />

Ms. Josephine D. Colon<br />

Colon Cancer Challenge Foundation<br />

Mr. Bruce Colville<br />

Community Foundation for<br />

Southeast Michigan<br />

Community Foundation <strong>of</strong><br />

Chattahoochee Valley, Inc.<br />

Community Foundation <strong>of</strong> Middle<br />

Tennesse<br />

Community Foundation <strong>of</strong> New Jersey<br />

Community Health Systems<br />

Foundation<br />

Comprehensive Care Center<br />

Mr. Kenneth Conboy<br />

Ms. Sheila Congdon<br />

Mr. Bryan Coniglio<br />

The Connell Company<br />

Mr. Christopher Connelly<br />

Ms. Wendy L. Conrad<br />

Ms. Sophie C. Consagra<br />

Consulting Cardiologists, P.C.<br />

Mr. Edward B. Conway<br />

Mr. John N. Conyngham, III<br />

Mr. David Cooper<br />

Ms. Esther Cooper<br />

Ms. Ann B. Copeland<br />

Ms. Sharon Copeland<br />

The Corey Foundation<br />

Ms. Alexandra Coria<br />

Ms. Louise Coria<br />

<strong>Cornell</strong> Black Pr<strong>of</strong>essional Women’s<br />

Forum<br />

<strong>Cornell</strong> Cinema<br />

<strong>Cornell</strong> University College Democrats<br />

Ms. Sylvia R. Corrigan<br />

Mr. Nathan D. Cortright<br />

Ms. Alice M. Costas<br />

Mr. Basil A. Costas<br />

Mrs. Susan Costas<br />

Cove Point Foundation<br />

Ms. Marion Cowan-Loh<br />

Ms. Hanley B. Cox<br />

Mr. Guy W. Cox, III<br />

Mr. Charles M. Crane<br />

Ms. Dana L. Cranmer<br />

Mr. Gerald Crawford<br />

Crawford Doyle Charitable Foundation<br />

Ms. Caroline Crim<br />

Ms. Anne Crisci<br />

Ms. Christina Croll<br />

Mr. Kevin Crosby<br />

Ms. Eliana Crosina<br />

Ms. Anna E. Crouse<br />

Mr. Jeffrey Crowley<br />

Ms. Judith M. Crowther<br />

Mr. Stephen Crumb<br />

Ms. Catherine L. Crumbo<br />

Mr. Juan R. Cruz<br />

Dr. Ward F. Cunningham-Rundles<br />

Ms. Barbara Curtis<br />

Mrs. Cynthia Cycon<br />

D<br />

D’Addario & Company, Inc.<br />

Mr. Anthony F. Daddino<br />

D’Agostino Foundation<br />

Ms. Mary Dague<br />

Ms. Marta C. Daire<br />

Dale C. Christensen Family Foundation<br />

Mr. Joseph R. Daly<br />

Selasi Dankwa<br />

Ms. Peggy Danziger<br />

Mr. Richard D’Aquila<br />

Rev. Joseph L. Darbouze<br />

Mr. Michael Dardia<br />

Ms. Gabrielle Darnell<br />

Mr. J. F. Dash<br />

Ms. Joanne Davenport<br />

Mr. William H. David<br />

David & Sarah Jane Charitable Trust<br />

The David and Alan Greene Family<br />

Foundation<br />

David Gotterere Charitable Trust<br />

David Zwirner, Inc.<br />

Mr. Robert C. Davidson,Jr.<br />

Mrs. Judy Davidson<br />

Ms. Susan Davis<br />

Dr. and Mrs. C. E. Davis<br />

Mr. Malcolm Davis<br />

Mrs. JoAnne Davis<br />

Mr. Hillel Davis<br />

Ms. Cornelia Davis<br />

Davita, Inc.<br />

Ms. Ellen Dawson<br />

Dr. Ype De Jong<br />

Ms. Carolyn C. De Wilde<br />

Ms. Laura Dechter<br />

Ms. Christine Decker<br />

Mr. and Mrs. Charles M. Defuccio<br />

Ms. Audrey Degutz<br />

Mr. Coloman DeHegedus<br />

Dr. Kirk W. Deitsch<br />

Mr. Mark Delaney<br />

Mr. Lyman Delano<br />

Ms. Mallory Delehanty<br />

Ms. Eileen Delgado<br />

Mr. Donald L. Dell<br />

Ms. Shirley W. Della Vecchia<br />

Ms. Yvette M. Delph<br />

Delta Partners Employees<br />

Delta Upsilon Fraternity - <strong>Cornell</strong><br />

Chapter<br />

Ms. Candace DeMatteis<br />

Mrs. Maxine Denmark<br />

Mr. Joseph Depaola<br />

Dr. Maria T. DeSancho<br />

Mrs. Kathleen DeSavino<br />

Mr. Paul H. Deschamps<br />

Mr. Neil V. Desena<br />

Ms. Edwine Desnoyers<br />

Mrs. Stefanie J. Detwiler<br />

Mr. Martin Deutsch, CPA<br />

Deutsche Bank North America<br />

Dr. Richard B. Devereux<br />

Mr. Richard A. Devine<br />

Mr. James Devine<br />

Ms. Marilyn J. Devine<br />

Mr. Peter Di Giulio<br />

Dr. Donna Di Michele<br />

Mr. William Diamond<br />

Ms. Teresa DiBernardino<br />

Ms. Samantha Dickinson<br />

Mr. Derek Dieter<br />

Dr. Joann Difede<br />

Ms. Helene R. Dillard<br />

Ms. Rebecca Dillingham<br />

Dr. Aihao H. Ding<br />

Ms. Andrea Dispigno<br />

Mr. Michael D. Ditzian<br />

Mrs. Ute A. Dobrick-Westwood<br />

Ms. Betty Doerfler<br />

Ms. Julie E. Dolan<br />

Mr. Matthew Dolan<br />

Ms. Pamela C. Donner<br />

Ms. Elizabeth Dorfman<br />

The Doris B. Goodwin Trust<br />

Doris Bry Trust<br />

The Dorothy and Arnold Neustadter<br />

Foundation<br />

Mrs. Patricia A. Dorph<br />

Mr. Bruce Dorskind<br />

Mrs. Ellen R. Doskow<br />

Ms. Diane M. Dougherty<br />

Ms. Kimberley Dow<br />

Ms. Amber Downer<br />

Mr. David Downs<br />

Dr. Robert C. and Veronica Atkins<br />

Foundation<br />

Mr. Arthur Dresner<br />

Ms. Helene Drobenare-Horwitz<br />

Mr. Mark T. Drooks<br />

Dr. Jeanine D. Dropkin,<br />

Mr. Arnold M. Drucker<br />

Dr. Lewis M. Drusin<br />

Ms. Joyce S. Dubensky<br />

Ms. Elizabeth D. Dufree<br />

Duke University<br />

Mr. Alan Dulit<br />

Mr. Alan S. Duncan<br />

Mr. Brian J. Dunlop<br />

Mrs. Barbara A. Dunn<br />

Ms. Kathryn Dupnik<br />

Mr. Richard Durst<br />

Mr. Leonid Duzhansky<br />

E<br />

E & R Rosenman Charitable<br />

Foundation<br />

East Side Cardiology, PLLC<br />

Dr. Gary E. Eddey<br />

Edelman Foundation<br />

Ms. Claire Edersheim<br />

Dr. Terri G. Edersheim<br />

Mr. David L. Edgerly<br />

Mrs. Linda Z. Edie<br />

Edith Baldinger Charitable Lead<br />

Annuity Trust<br />

Edward P. Evans Foundation<br />

Mrs. Zina S. Egol<br />

Mrs. Norma Ehrlich<br />

Mr. George P. Eichen<br />

Mr. Roger W. Einiger<br />

Mr. L. C. Einwick, Jr.<br />

Mr. Stanley S. Eisenstat<br />

Mr. Edgar Eisner<br />

Eissa A. Bateh and Brothers<br />

Foundation, Inc.<br />

Elberon Development Company<br />

Ms. Gertrude Elins<br />

Ms. Marjorie Ellenbogen<br />

Mr. Peter W. Elliott<br />

Mrs. Ruth Elsner<br />

Dr. Rebecca L. Elstrom<br />

Mr. Ben A. Emanuel<br />

Mrs. Carol Emberson<br />

The Emily Davie and Joseph S.<br />

Kornfeld Foundation<br />

Emily L. and Robert E. Smith<br />

Foundation<br />

Mrs. Linda R. Emory<br />

Ms.Christine E. Endicott<br />

Dr. Angie M. Eng<br />

Ms. Theresa L. Enk<br />

Mr. Chris Enock<br />

Mr. Tom Enroth<br />

Entertainment Industry Foundation<br />

Mr. Alan Epstein<br />

Epstein Teicher Philanthropies<br />

Ernst Foundation, Inc.<br />

Ms. Deborah J. Esser<br />

Estate <strong>of</strong> Anne Ellen Wigmore<br />

Estate <strong>of</strong> George H. Dunning<br />

Estate <strong>of</strong> Gilberto Zaldivar<br />

Estate <strong>of</strong> Suzanne C. Murphy<br />

Ms. Paige Etter<br />

Dr. Arthur T. Evans<br />

F<br />

Evelyn Y. Davis Foundation<br />

Mr. Stephen Everett<br />

Ms. Ilaria Falciatori<br />

Wei Fan<br />

Ms. Elizabeth Fansher<br />

Ms. Mary Farag<br />

Ms. Vivian S. Farah<br />

Mr. and Mrs. Frank Farinella<br />

Blue Farms<br />

Mr. Joseph R. Favata<br />

Ms. Gail M. Federici<br />

Dr. Oliver T. Fein<br />

Mrs. Phyllis M. Feinert<br />

Mr. Robert E. Feldbaum<br />

Dr. Eric J. Feldman<br />

Ms. Harriet Feldmann<br />

Mr. and Mrs. Richard Feldstein<br />

Feldstein Family Charitable Foundation<br />

Mr. Thomas H. Ferguson<br />

Dr. Bernard T. Ferrari<br />

Ferrari Consultancy<br />

Ms. Lucille Ferraro<br />

Richard Ferri<br />

Fidelity Charitable Gift Fund<br />

Mr. A. G. Fieger<br />

Mr. Brent Field<br />

Filomen M. D’Agostino Foundation<br />

Corp<br />

Ms. Kay Findlater<br />

Jamie Findlater<br />

Ms. Ilene Fine<br />

Mr. Marion Finizio<br />

Dr. Madelon L. Finkel<br />

Dr. Joseph J. Fins<br />

Mr. Christopher Fiorese<br />

Ms. Edmee D. Firth<br />

Ms. Constance F. Fischer<br />

Mr. John Fisher<br />

Mrs. Dena Fisher<br />

Ms. Carol A. Fisher<br />

Fisher-Raviv Family Foundation<br />

Mr. Magnus Fiskesj<br />

Mr. John W. Fitzgerald<br />

Mr. Maurice J. Fitzgerald<br />

Mr. Robert F. Fitzgerald<br />

Mrs. Winifred M. Fitzgerald<br />

Mr. Stephen M. Fitzgibbons<br />

Ms. Lisa A. Fitzgibbons<br />

Mr. John Flanagan<br />

126 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 127


2010 Donors continued<br />

Fleischaker Family Foundation<br />

Mr. Eric G. Fleming<br />

Ms. Phyllis Fliederbaum<br />

Mrs. Eva K. Flores<br />

Mr. Philip Flowers<br />

Dr. John T. Flynn<br />

Ms. Sabrina Fondren<br />

Mr. Thomas M. Fontana<br />

Ms. Sarah Foote<br />

Ms. Charlotte M. Ford<br />

Mr. Bryan Ford<br />

Ms. Patty Forgham-Thrift<br />

Mr. Mark Forman<br />

Formatech, Inc.<br />

Mr. Christopher A. Forster<br />

Mr. Mark Foster<br />

Foster Davis Foundation, Inc.<br />

Ms. Abigail Foulk<br />

Ms. Diane L. Fowlkes<br />

Mrs. Arlene M. Fox<br />

Ms. Lissete A. Fox<br />

Ms. Kathy G. Frank<br />

Dr. Maura D. Frank<br />

Mrs. Phyllis Frankel<br />

Ms. Elisabeth Franklin<br />

Mr. H. M. Fraser<br />

Mr. Laurence Freedman<br />

Ms. Martina Frey<br />

Mr. Francoise Freyre<br />

Mr. Sam Friedlander<br />

Mr. Mitchell R. Friedman<br />

Mr. Peter R. Friedman<br />

Friedwald Center for Rehabilitation<br />

and Nursing, LLC<br />

Friman & Stein, Inc.<br />

Mr. Jules B. Fromm<br />

Frontier Science and Technology<br />

Research Foundation, Inc.<br />

Mr. Henry Fruhauf<br />

Ms. Susan Frye<br />

Ms. Sachiko Funaba<br />

Mr. Pincus F. Fund<br />

Mr. Nelson T. Fung<br />

Mrs. Beth Furman<br />

Ms. Margaret L. Furman<br />

Dr. Richard R. Furman<br />

G<br />

Mrs. Ava-Dawn Gabbidon<br />

Mrs. Elfriede M. Galicich<br />

Mrs. Catherine A. Gallagher<br />

Mr. Joel Gallant<br />

Ms. Donna Galloway<br />

Dr. and Mrs. Daniel Gardner<br />

Mr. Pierce Gardner<br />

Mr. Samual Garner<br />

Ms. Susan Garwood<br />

Mr. David Gasser<br />

Mrs. Louise M. Gatanas<br />

Gateway School <strong>of</strong> New York<br />

Mrs. Virginia B. Gausden<br />

Ms. Robin Gauthier<br />

Mohan Gawande<br />

Ms. Richa Gawande<br />

Dr. Mitchell L. Gaynor<br />

GCC Travel, LLC<br />

Ms. Leah Geach<br />

Ms. Maria Geffen<br />

Mr. Anthony Geiss<br />

Dr. Brian Gelbman<br />

Ms. Victoria Gelfand<br />

Ms. Sandra M. Genelius<br />

Genentech USA<br />

General Atlantic Service Company, LLC<br />

Georgescu Family Foundation<br />

Georgetown University<br />

Mr. Angelos Georgopoulos<br />

Ms. Vivian C. Georgousis<br />

Dr. Darin J. Geracimos<br />

Dr. Linda M. Gerber<br />

Mr. Kevin J. Gershfeld<br />

Ms. Erica Gersowitz<br />

Ms. Suzanne Gervais<br />

Ms. Nikki Gettinger<br />

Mr.Partho Ghosh<br />

The Giammalva Family<br />

Foundation<br />

Mrs. and Mrs. Constance B. Gibb<br />

Mrs. Margot S. Gibson-Beattie<br />

Ms. Kristin Gilbert<br />

Ms. Edes P. Gilbert<br />

Mr.James G. Gilbert<br />

Ms. Tara Gilhooly<br />

Mr. S. H. Gillespie<br />

Mr. Carl Ginet<br />

Mr. Christopher Ginter<br />

Ms. Megan Gioiella<br />

Mr. Robert L. Gipson<br />

Mr. Daniel Gitlin<br />

Mr. Marvin S. Gittes<br />

Mr. Michael O. Gittlesohn<br />

Ms. Diane Giulio<br />

Mrs. Jennifer Given<br />

Ms. Gelila Gizaw<br />

Mr. Bruce Gladden<br />

Mr. Edward F. Glassmeyer<br />

Ms. Elizabeth Glater<br />

Mr. Peter H. Gleason<br />

Mrs. Helene Gleeman<br />

Dr. Marshall J. Glesby<br />

Ms. Frances Glick<br />

Global Health Strategies<br />

Dr. David L. Globus<br />

Mr. John F. Glynn<br />

Ms. Barbara Godard<br />

Ms. Catherine C. Godfrey<br />

Ms. Pamela Gokemeijer<br />

Ms. Karen B. Gold<br />

Ms. Lori Goldberg<br />

Ms. Marcia B. Goldberg<br />

Ms. Michele D. Goldberg<br />

Ms. Leslie E. Goldblatt<br />

Mr. Marc Goldfarb<br />

Mr. Andrew Goldfine<br />

Mr. and Mrs. Edward Goldman<br />

Goldman Sachs & Co.<br />

Goldman Sachs & Co. Matching Gift<br />

Program<br />

Goldman Sachs Gives<br />

Mr. Herman C. Goldsmith<br />

Mr. Walter R. Gonzales<br />

Mr. Anthony C. Gooch<br />

Mrs. Jennifer Goodman<br />

Goodman Charitable Trust<br />

Ms. Ann Goodrich<br />

Mr. Matthew Goodwin<br />

Mr. Stephen Goodwin<br />

Mr. Lawrence E. Gore<br />

Dr. Kenneth J. Gorelick<br />

Mr. Samuel Gorovitz<br />

Gotham Yard Corp.<br />

Mr. Robert J. Gotterer<br />

Mr. Gene Gottesman<br />

Ms. Katherine Gottschalk<br />

Hariprasad Govinda<br />

Mrs. Mary B. Grace<br />

The Grace R. and Alan D. Marcus<br />

Foundation<br />

Mr. Donald E. Graham<br />

Parrie Graham<br />

Mr. David Green<br />

Mrs. Margaret Greenberg<br />

Ms. Julie Greenman<br />

Dr. Alan Greenspan<br />

Dr. Ruth B. Greer<br />

Mr. Robert Greer<br />

Ms. Jennifer Grenier<br />

Mr. John A. Griffin<br />

Miss Jeanne A. Grifo<br />

Mrs. Kendra Grosso<br />

Mr. William C. Gruber<br />

Ms. Pamela Gruber<br />

Mr. William Grueskin<br />

Ms. Arlene Solomon Haas Guerra<br />

Mrs. Nancy B. Guerrant<br />

Mr. Eileen Guida<br />

Dr. and Mrs. Subhash C. Gulati<br />

Dr. Roy M. Gulick<br />

Mrs. Catherine L. Gunsbury<br />

Mr. Ilya M. Gurtenboim<br />

Elan Guterman<br />

Mr. Steven L. Gutman<br />

Dr. Sidney Gutstein<br />

Ms. Leslie Gyson<br />

H<br />

H & M Bar, LLC<br />

Ms. Rose Haas<br />

Hachette Book Group<br />

Hackers for Hope<br />

Hadassa Antiques, Inc.<br />

Mrs. Esther Haddad<br />

Hagedorn Fund<br />

Dr. Katherine A. Hajjar<br />

Ms. Lynn Halbfinger<br />

Ms. Margo Halle<br />

Mrs. Toula J. Halperin<br />

Mr. Craig M. Halpin<br />

Mrs. Doris Hambro<br />

Dr. Scott M. Hammer<br />

Mr. Joel Handel<br />

Mr. Jerry S. Handler<br />

Mr. Richard Handman<br />

Mr. James M. Handy<br />

Mr. Jeffrey R. Hannah<br />

Ms. Carla Hanson<br />

Ms. Joann Hanson<br />

Mr. Matthew Hare<br />

Mr. James J. Hargadon<br />

Dr. Ray Hargreaves<br />

The Harjen Charitable Foundation<br />

Harmonious Lifestyles, Inc.<br />

The Harold and Mimi Steinberg<br />

Charitable Trust<br />

Harriette A. Gifford Charitable<br />

Remainder Trust<br />

Mr. Alan B. Harris<br />

Ms. Christina Harris<br />

Ms. Eva Harris<br />

Ms. Mary Harrity<br />

Mr. Vincent Hart<br />

Mr. Gurnee F. Hart<br />

Mr. Steven W. Hart<br />

Dr. Barry J. Hartman<br />

The Harvey and Ruth Gelfenbein<br />

Charitable Foundation<br />

Mr. Rifat Hasan<br />

Mr. Jonathan Hassell<br />

Mr. James Haustein<br />

Mr. Frank H. Hawrylak<br />

Dr. Frances G. Haxton<br />

Mr. Mark Hayman-Martinez<br />

Ms. Jodi Hazan<br />

Hazen Polsky Foundation<br />

Mr. Donald R. Head<br />

Healthcare Initiatives<br />

Ms. Katrina Hedlesky<br />

Ms. Deborah L. Hedwall<br />

Ms. Dorothy J. Heger<br />

Mr. Emil Heidkamp<br />

Ms. Rebecca A. Heidkamp<br />

Ms. Rose T. Heim<br />

Mr. Douglas C. Heimburger<br />

Mr. Melvin L. Heineman<br />

Mrs. Drue J. Heinz<br />

Helene Whitman Memorial Cancer<br />

Fund<br />

Dr. David C. Helfgott<br />

Dr. Arthur D. Heller, F.A.C.P.<br />

The Help for People Foundation Trust<br />

Dr. Hugh C. Hemmings, Jr.<br />

Mrs. Pamela Hemphill<br />

Dr. Barbara L. Hempstead<br />

Ms. Ruth Hendel<br />

Mrs. Judith Henderson<br />

Ms. Mary Hennigan<br />

Henry & Ida Richard Foundation<br />

Henry Schein Cares Foundation, Inc.<br />

Herbert Rogowsky Foundation, Inc.<br />

Ms. Anna Herforth<br />

Mr. Daniel A. Hernandez-Rodriguez<br />

Mr. John Herold<br />

Dr. Edmund M. Herrold<br />

Ms. Lindsay Herron<br />

Mr. and Mrs. Morton E. Hertzmark<br />

Ms. Anne-Claire Hervy<br />

Mr. John Herzog<br />

Ms. Eileen Hess<br />

Mr. Jim Hessburg<br />

Ms. Elizabeth Hester<br />

Mrs. Tara A. Higgins<br />

Mr. Robert L. Higgins<br />

Dr. Shanna S. Hill<br />

Hillcrest Church <strong>of</strong> Christ<br />

The Hilson Fund, Inc.<br />

Mr. Andrew Him<strong>of</strong>f<br />

Mr. Frances M. Hines<br />

Ms. Lisa A. Hipwell<br />

Mr. Martin S. Hirsch<br />

Ms. Joan R. Hirschfeld<br />

Mr. Brandon Ho<br />

Dr. David Hochman<br />

Dr. Eugenia S. Hochman<br />

Mrs. Leslie C. Hoddeson<br />

Mr. Frank Hoehne<br />

Ms. Kathryn Hoenig<br />

Mr. David H<strong>of</strong>fman<br />

Ms. Ivy H<strong>of</strong>fman<br />

Mr. Joel H<strong>of</strong>fman<br />

Ms. Julie H<strong>of</strong>fman<br />

Mr. Peter Hohendahl<br />

Ms. Joan Holloway<br />

Holly Andersen Heart Foundation<br />

Mr. David Holowka<br />

Ms. Patricia K. Holt<br />

Holy Trinity Church<br />

Mr. James E. Hook<br />

Dr. Jaleh E. Hoorfar<br />

Hope Through Healing Hands<br />

Mr. David Horan<br />

Ms. Lucy P. Horn<br />

Mr. Robert A. Horne<br />

Dr. James M. Horowitz<br />

Hospital for Special Surgery<br />

Mr. Eric Houpt<br />

Mr. Rob Houtenbos<br />

Mr. Steven Howard<br />

Howard G. Smith Trust<br />

Mr. David S. Howe<br />

Mr. Charles Howell<br />

Mrs. Monica Howland<br />

Ms. Francy E. Hoyos<br />

Mr. Henry H. Hoyt, Jr.<br />

HSBC Philanthropic Programs<br />

Mr. Bert Huang<br />

Mr. Richard Hubbard<br />

Mrs. Nancy M. Huber<br />

Ms. Caroline Huddleston<br />

Hudson News Distributors<br />

Mr. Robert Huff<br />

Mr. Mark Huffman<br />

Mrs. Mary O. Hughes<br />

Mrs. Mary P. Hulitar<br />

Mr. Ralf Hulsmann<br />

Mr. Kenneth Hung<br />

Ms. Katherine Hunting<br />

Dr. James R. Hurley<br />

Mr. Felix Hyppolite<br />

I<br />

Ms. Maureen A. Iadevaia<br />

Ms. Susan Iadevaia<br />

IBEC Building Corporation<br />

ICAP Service North America, LLC<br />

Independence School P.S. 234<br />

The Indu Foundation<br />

Infectious Diseases Society <strong>of</strong><br />

America Education and Research<br />

Foundation<br />

Dr. Barton Inkeles<br />

Dr. Lawrence A. Inra<br />

International Association <strong>of</strong><br />

Physicians in Aids Care<br />

Mrs. Barbara E. Inturrisi<br />

Dr. and Mrs. Charles E. Inturrisi<br />

Ira M. Resnick Foundation, Inc.<br />

Irene S. Fisher and Barry L. Fisher<br />

Charitable Trust<br />

Mr. Robert R. Irving<br />

Ms. Diana H. Irwin<br />

Isak & Rose Weinman Foundation<br />

Ms. Sarah Israel<br />

J<br />

J.P. Morgan Chase<br />

Ms. Beverly Jablons<br />

Dr. Lois A. Jackson<br />

Mr. Leonard Jackson<br />

Ms. Arlene Jacobi<br />

Mr. and Mrs. Bruce Jacobs<br />

Mr. Peter B. Jacobs<br />

Dr. Michael W. Jacobson<br />

Dr. Ira M. Jacobson<br />

Ms. Joanne Jacobson<br />

Jaffe DDS, Duvalsaint DDS & Siegel<br />

DMD, PC<br />

Mrs. Jaclyn G. James<br />

Ms. Holly Janes<br />

Ms. Carmen Jaquez<br />

Mr. Andrew Jarecki<br />

Ms. Katherine Jaris<br />

Dr. Charles I. Jarowski, Jr.<br />

Mr. Zachary Jarvis<br />

Jatoma Charitable Foundation, Inc.<br />

JB Precious Jewels<br />

Ms. Ashley Jeanlus<br />

Mr. Jean P. Jeannet<br />

Ms. Nancy Jeffries<br />

Ms. Jean Jenkins<br />

Ms. Elizabeth Jensen<br />

Jerome and Laura Dorfman<br />

Charitable Foundation<br />

Ms. Sandra A. Jerro<br />

The Jewish Communal Fund<br />

Mr. Bruce R. Jocz<br />

John N. Conyngham III & Lou C.<br />

Conyngham Family Charitable<br />

Foundation<br />

Mrs. Judith Johnson<br />

Ms. Lauren Johnson<br />

Mr. Manuel Johnson<br />

Ms. Patricia Johnson<br />

Dr. Warren D. Johnson, Jr.<br />

Johnson & Johnson Corporate<br />

Ms. Joan Johnston<br />

Mr. Andrew Johnstone<br />

Dr. Erica C. Jones<br />

Ms. Laura Jones<br />

Ms. Mary G. Jones<br />

Joodayoh, Inc.<br />

The Joseph Gluck Foundation<br />

The Joseph R. Daly Foundation<br />

Mr. Ragnhild Jost<br />

Ms. Johanna Joyce<br />

Julia Green Elementary School<br />

The Julian Rashkind Trust<br />

The Junction<br />

Ms. Susan Jureller<br />

Justgive.Org<br />

K<br />

Ms. Linda Kabumoto-Gras<br />

Mr. Solomon Kahn<br />

Mrs. Michelle Kaiser<br />

Terry Kaiura<br />

Mr. Jonathan Kalb<br />

Mr. Peter S. Kalikow<br />

Dr. Charles J. Kallick<br />

Mrs. Sheila Kamerman<br />

Mr. Stephen M. Kaminsky<br />

Ms. Hazel S. Kandall<br />

Nivedita Kanjilal<br />

Dr. Jed S. Kanner<br />

Mrs. Ann Kanthor<br />

Mrs. Leah I. Kantor<br />

Kaplan Living Trust<br />

Mr. Alon Kaplun<br />

Ruchi Kapoor<br />

Ms. Michele Karantsavelos<br />

Ms. Lucine Karjian<br />

Ms. Soraya Kashani<br />

Katherine John Murphy Foundation<br />

Mr. Bruce Katona<br />

Mr. Peter J. Katzenstein<br />

Mr. Eli W. Kaufman<br />

Masae Kawamura<br />

Ms. Anne L. Keating<br />

Mr. Richard J. Keating<br />

Keck School <strong>of</strong> <strong>Medicine</strong><br />

Dr. Michael C. Keefer<br />

Mr. William Keel<br />

Keene Elm City Rotary Club<br />

Mrs. Bridget Keepman<br />

Ms. Virginia Keeshan<br />

Ms. Marcia Keizs<br />

Mr. Peter B. Kellner<br />

Dr. Kevin V. Kelly<br />

Mr. and Mrs. Daniel C. Kenary<br />

Dr. Robert O. Kenet<br />

Ms. Caroline B. Kennedy<br />

Mr. Tom Kennedy<br />

Dr. Otto F. Kernberg<br />

Kevin and Susie Davis Foundation<br />

Mr. Mohammed A. Khan<br />

Mr. Sumeet Khetarpal<br />

Ms. Eva Kiczkowski<br />

Mrs. Nancy L. Kienzle<br />

Mr. Robert J. Killie<br />

Ms. Kelly L. Kim<br />

Mr. Paul Kim<br />

Ms. Sue Kim<br />

Ms. Sunny Kim<br />

Mr. and Mrs. Stanley M. Kimball<br />

Ms. Sara Kimbell<br />

Kimberly-Clark Corporation<br />

Mr. Michael Kimerling<br />

Mr. Nils A. Kindwall<br />

Ms. Diana King<br />

Ms. Sherry P. King<br />

Mr. Joel King<br />

Ms. Janice King<br />

The Kingsberg Foundation<br />

Kinray, Inc.<br />

Ms. Glenda Kirby<br />

Mr. Garrett Kirk, Jr.<br />

Mrs. Dorothy D. Kirkman<br />

The Kirschenbaum Charitable<br />

Foundation<br />

Mr. Anand Kishore<br />

Mr. Sandeep T. Kishore<br />

Mr. Stephen M. Kittenplan<br />

Mrs. Cynthia A. Kleeberger<br />

Dr. and Mrs. Harvey Klein<br />

Dr. Ludwig Klein<br />

Mrs. Elizabeth S. Klein<br />

Ms. Hildabeth Klein<br />

Ms. Judith M. Kleinberger<br />

Ms. Kim Kleine<br />

Dr. Paul D. Kligfield<br />

Ms. Toni Klimowski<br />

Mr. Jeffrey A. Klym<br />

Ms. Pamela A. Knox<br />

Dr. Albert I. Ko<br />

Ms. Beryl Koblin<br />

Mr. Daniel Koch<br />

Mr. Andreas Koeck<br />

Mr. Nii O. Koney<br />

Mrs. Mary Ann M. Koontz<br />

128 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 129


2010 Donors continued<br />

Mr. Brian Korb<br />

Korda Herskovits Caplan<br />

Philanthropic Fund<br />

Mr. Marvin H. Koslow<br />

Ms. Rosemary Kraemer<br />

Ms. Alysa Krain<br />

Mr. Larry Kramer<br />

Mrs. Susan Kramer<br />

Dr. Daniel G. Krauser<br />

Mr. Keith Krayer<br />

Ms. Brenda M. Krepol<br />

Mr. Matthew Kretzer<br />

Mr. Michael F. Krist<strong>of</strong>f<br />

Ms. Ludmila Krivitsky<br />

Ms. Joan Kron<br />

Boudewijn Kruith<strong>of</strong><br />

Ms. Kristin Kruse<br />

Ms. Lori M. Kryspin<br />

Ms. Brita Kube<br />

Ms. Judith Kuhn<br />

Mr. John H. Kuhnle<br />

Yuichi Kumagai<br />

Ms. Jill Kunkel<br />

Ms. Deborah Kurtz<br />

Ms. Mary Kush<br />

Ms. Ileana Kutler<br />

Ms. Sally J. Kuzma<br />

L<br />

Mr. Douglas Labar<br />

Ms. Sandra LaBlance<br />

Dr. Mark K. Lachs<br />

Mrs. Julia Lagermesulam<br />

Mr. Leo Lahm<br />

Ms. Susan Lake<br />

Ms. Dwandra N. Lampkin<br />

Mr. Nicholas Landsman<br />

Dr. Brian R. Landzberg<br />

Mrs. Barbara H. Lang<br />

Ms. Danielle Laraque<br />

Ms. Christine Larchian<br />

Mr. Edwin M. Larkin<br />

Mr. Robert LaRocca<br />

Dr. Davise H. Larone<br />

Ms. Christine Lasala<br />

Ms. Carol Lasek<br />

Ms. Deborah A. Lasher<br />

Ms. Margaret Lauck<br />

Dr. Jack A. Laufer,<br />

Ms. Megan Laughlin<br />

Mr. Jeffrey G. Laupus<br />

Laurence Levine Charitable Fund, Inc.<br />

Dr. Michael H. Lavyne<br />

Law Firm <strong>of</strong> Allen Rothenberg<br />

Mr. Elliot Lawrence<br />

Lawrence & Sheri Babbio Foundation<br />

Lawrence Gelb Foundation<br />

Mr. Wayne Lawson<br />

Lazard Capital Markets, LLC<br />

Jade Le<br />

Ms. Eileen Leavitt<br />

Lebensfeld Foundation<br />

Mr. Michael Lederman<br />

Mr. Rhoady Lee<br />

Dr. Thomas C. Lee<br />

Mr. Tom Lee<br />

Ms. Minako Y. Lee<br />

Ms. Linda Lee<br />

Mr. Darin K. Lee<br />

Ms. Jane Lee<br />

Ms. Jacqueline S. Leeds<br />

Ms. Allison G. Leff<br />

Mr. David Lefty<br />

Ms. Sandra Lehrman<br />

Dr. Marcia E. Leikin<br />

Ms. Marguerite Lembo<br />

Ms. Stephanie N. Lemus<br />

Leo Rosner Foundation, Inc.<br />

Mr. John Leonard<br />

Dr. John P. Leonard<br />

Ms. Elaine Leong<br />

Dr. and Mrs. Bruce B. Lerman<br />

Ms. Nancy Lerner<br />

Ms. Susan H. Lerner<br />

Ms. Jaclyn Lesch<br />

Ms. Lory Leshin<br />

Ms. Elizabeth Lesnick<br />

Mr. Joseph S. Lesser<br />

Mr. Scott Letendre<br />

Dr. and Mrs. Howard M. Levin<br />

Mr. Andrew Levine<br />

Ms. Beth C. Levine<br />

Ms. Carol Levine<br />

Mr. H. F. Levine<br />

Mr. Irwin R. Levine<br />

Ms. Linda Levine<br />

Mr. Michael J. Levine<br />

Mr. Simon Levine<br />

Ms. Gloria Levinson<br />

Levinson Living Trust<br />

Ms. Ellen Levy<br />

Ms. Lorriane Levy<br />

Mr. Richard Levy<br />

Mr. Todd Levy<br />

Levy Hermanos Foundation, Inc.<br />

Mr. Daniel Lewis<br />

Dr. Daniel M. Libby<br />

Mr. John N. Lieber<br />

LifeWatch<br />

Mr. Richard Lifton<br />

Lighthouse Financial Group<br />

The Lightship Group<br />

Ms. Deborah Lilley<br />

Yee Lim<br />

Ms. Tina Lim<br />

Dr. Harvey A. Linc<strong>of</strong>f<br />

Mr. Daniel T. Lindsey<br />

Ms. Robin B. Linfield<br />

Mrs. Daniella Lipper-Coules<br />

Mrs. Lini Lipton<br />

Mrs. Phyllis Lisi<br />

Mr. Joseph Lisi<br />

Ms. Leigh S. Lisowski<br />

Dr. Harold Litvak<br />

Mrs. Daniella Livnat-Daids<br />

Mr. Michael Locher<br />

Dr. Lia S. Logio<br />

Mr. Richard Long<br />

Mr. John G. Long, Jr.<br />

Mr. Guy Longobardo<br />

Mr. David Looney<br />

Dr. Jorge A. Lopez-Ovejero<br />

Mr. Lherif Loraamm<br />

Mr. Thomas Loredo<br />

The Louis K. Brandt Foundation<br />

Louis & Rachel Rudin Foundation<br />

Louis & Rose Klosk Fund<br />

Mr. George T. Lowy<br />

Mr. Angelo M. Lucrezia<br />

Mr. Edward J. Ludwig<br />

Ms. Molly Luetkemeyer<br />

Ms. Anne Luetkemeyer<br />

Luetkemeyer Jr. Family Foundation, Inc.<br />

Mrs. Joy C. Luke<br />

D. R. Lund<br />

Mrs. Janet Lupinacci<br />

Mr. Robert Luskin<br />

The Lymphoma Foundation<br />

Mr. James J. Lynch<br />

Ms. Jennifer Lynham<br />

Ms. Lisa Lyons<br />

M<br />

M & T Logistics, Inc.<br />

M.A.C. AIDS Fund<br />

Ms. Jeanne MacAluso<br />

Ms. Carol MacCorkle<br />

Ms. Patricia A. MacCubbin<br />

Ms. Elaine MacDonald<br />

Mr. John MacDonald<br />

Mr. Randy MacDonald<br />

Mrs. Patricia A. Maciel<br />

Mrs. Jane Mack<br />

Ms. Ilene Mack<br />

Ms. Terra Mackintosh<br />

Mr. Robert L. MacNaughton<br />

Macy’s Foundation<br />

Mr. Donald P. Madden<br />

Mr. David C. Maddux<br />

The Madeira School<br />

Ms. Akiko Maeda<br />

Dr. Richard J. Mahler, FACP<br />

Mrs. Margaret L. Mallett<br />

Malone/Kremer, Inc.<br />

Manatt, Phelps & Phillips, LLP<br />

Mr. Lewis R. Mandel<br />

Mr. Joseph M. Mandel<br />

Dr. Cheriparambil K. Mani<br />

Dr. Samuel J. Mann<br />

Ms. Shaila Manyam<br />

Mr. Steven J. Maranz<br />

Mrs. Pearl Marcell<br />

Dr. Aaron J. Marcus<br />

Mr. Charles Marcus<br />

Ms. Natalie Marcus<br />

Margaret Ralph & Associates<br />

Mariner Investment Group, Inc.<br />

Mr. Stephen Mark<br />

Dr. Steven M. Markowitz<br />

Dr. Kristen M. Marks<br />

MARMA Foundation<br />

Mr. James C. Marques<br />

Ms. Camila Marquez<br />

Ms. Ellen R. Marram<br />

The Marrus Family Foundation, Inc.<br />

Mr. and Mrs. Charles J. Marsden<br />

Mrs. Yvonne Marsh<br />

Mr. Edgar J. Marston, III<br />

Ms. Elaine S. Martin<br />

Mr. Robert G. Martin<br />

Ms. Rosemary Martin<br />

Mr. William Martin<br />

Martin L. Berman Foundation<br />

Marvin and Barbara Eisenstadt<br />

Charitable Foundation<br />

Mary A. Furlong Revocable Trust<br />

Mary W. Harriman Foundation<br />

Ms. Karen Maschke<br />

Ms. Susan L. Mascitelli<br />

Ms. Marie B. Maser<br />

Ms. Gina Masi<br />

Dr. Bassem Masri<br />

Massachusetts Medical Society<br />

Ms. Ann C. Mathews<br />

Mr. James Mathews<br />

Mathis Pfohl Foundation<br />

Ms. Carol Matthieu<br />

Mr. John Mattioli<br />

Mr. David Mauel<br />

Dr. Frederick Maxfield<br />

Ms. Catherine P. May<br />

Ms. Joan May<br />

Mr. John May<br />

Mayor’s Fund to Advance<br />

New York City<br />

Mr. Robert Mazelin<br />

Ms. Jessica Mazzeo<br />

Ms. Diane L. McAleer<br />

Mr. John McAleer<br />

Mr. Patrick McAleer<br />

Dr. Sarah J. McAleer<br />

Mr. Hawley H. McAuliffe<br />

Mr. Jonathan E. McBurney<br />

Mrs. Maria G. McCabe<br />

Ms. Rachael McClennen<br />

Mrs. Frances T. McClennen<br />

Mrs. Joanna McClure<br />

Ms. Mary Mcclymont<br />

Mr. Will McConnell<br />

Mr. Kevin C. McCooey<br />

Mr. Frederick R. McCord<br />

Ms. Candice S. McCoy<br />

Ms. Julia McCullough<br />

Mr. J. A. McCutchan<br />

Ms. Jeanne McDermott<br />

Ms. Barbara B. McGhie<br />

Mrs. Sally L. McGinn<br />

Ms. Catherine McGowan<br />

Ms. Amy McGowan<br />

Mr. Sean McIntyre<br />

Mrs. Nancy McKenna<br />

Ms. Katherine McLaughlin<br />

Mr. Mark L. McLeland<br />

Ms. Cara McMillin<br />

Ms. Catherine S. McMullen<br />

Mr. Thomas P. McMullen<br />

Mrs. Elizabeth C. McNicholas<br />

Ms. Sally McNulty<br />

Mrs. Kathryn M. McPherson<br />

Medco Health Solution Charitable<br />

Match Fund<br />

Medtronic, Inc.<br />

Ms. Susan S. Meeker<br />

Anuj B. Mehta<br />

Mrs. Ruth Meier<br />

Dr. and Mrs. Joseph P. Mele<br />

Dr. Ellen M. Mellow<br />

Memorix, Inc.<br />

Mr. Mukund Menda<br />

Mr. Rich Menendez<br />

Mr. Gary Mennitt<br />

Mr. Robert B. Menschel<br />

Dr. Wendy L. Mercier<br />

Merck<br />

Merck Partnership for Giving<br />

Mercury Communications Group, LLC<br />

Meredith Corporation<br />

Mr. Thomas Merkel<br />

Ms. Margaret Merriam<br />

Dr. and Mrs. Samuel T. Merrick<br />

Mrs. Elizabeth N. Merrick<br />

Mr. Alfredo Mesa<br />

Mr. Anthony P. Messent<br />

Ms. Lorrie Messinger<br />

Ms. Barbara Metch<br />

Metropolitan Baptist Church<br />

Ms. Helen N. Mettler<br />

Ms. Genevieve Meyer<br />

Mrs. Anne B. Meyercord<br />

Mr. Richard Mezan<br />

Ms. Randi Michel<br />

Dr. Shari R. Midoneck<br />

Ms. Lucille M. Mikes<br />

Ms. Ellen Milberg<br />

Ms. Lillian Miles<br />

Ms. Roberta Militello<br />

Mrs. Sharon J. Millard<br />

Mrs. Amy Miller<br />

Ms. Angela Miller<br />

Ms. Barbara L. Miller<br />

Mr. Dennis Miller<br />

Ms. Emily Miller<br />

Ms. Madelyn Miller<br />

Ms. Margaret Miller<br />

Mr. Michael C. Miller<br />

Ms. Rachel Miller<br />

Mr. Stuart A. Miller<br />

Ms. Barbara A. Minakakis<br />

Mr. Eric Mindich<br />

Mr. Matthew Mirapaul<br />

Dr. Paul F. Miskovitz<br />

Mitchell & Margo Blutt Family<br />

Foundation<br />

Mr. and Mrs. David M. Modest<br />

Ms. Kate M<strong>of</strong>fitt<br />

Mr. and Mrs. Morris A. Mondschein<br />

Mrs. Sarah K. Monego<br />

Mr. Charles M. Monroe<br />

Ms. Liliana Montano<br />

Mr. Kenneth Monteiro<br />

Dr. Anne Moore<br />

Mr. Benjamin Moore<br />

Ms. Ellis O. Moore<br />

Ms. Karen Moore<br />

Ms. Kate L. Moore<br />

Ms. Nicole Moore<br />

Mr. Richard A. Moore, Jr.<br />

Mr. Daniel Morgan<br />

Dr. William A. Morgan<br />

Morgan Stanley<br />

Morgan Stanley Smith Barney Global<br />

Impact Funding Trust, Inc.<br />

Mrs. Maureen A. Mosca<br />

Mr. Scott Mosser<br />

Ms. Katie Mostero<br />

Ms. Nicole Mott<br />

Mr. Dimitri Moumoutjis<br />

Ms. Manuela Mozo<br />

Mr. David Mulgrum<br />

Ms. Mary B. Mullin<br />

Mrs. Marian B. Munson<br />

The Murphy Family Foundation<br />

Mr. Donald B. Murphy<br />

Ms. Jane Murphy<br />

Ms. Patricia Murphy<br />

Dr. Robert L. Murphy<br />

Dr. Susan H. Murphy<br />

Mr. Joseph Murray<br />

Dr. Joseph F. Murray<br />

The Murray Alon Charitable<br />

Foundation<br />

Sricharan Murugesan<br />

Muslim Educational and Cultural<br />

Association<br />

Dr. Elizabeth C. Muss<br />

Mrs. Leticia Muttera<br />

Mr. Robert C. Myers<br />

Mrs. I. Slayton Myers<br />

Mrs. Susan H. Mygatt<br />

Mr. Eric Myser<br />

N<br />

Dr. and Mrs. Ralph L. Nachman<br />

Dr. and Mrs. Jerry Nagler<br />

Rakesh Nagula<br />

Ms. Heather A. Nahas<br />

Yoriko Nakamura<br />

Mr. Yasumitsu Nakano<br />

The Nancy and John H<strong>of</strong>fmann<br />

Foundation<br />

Mr. Robert Nankin<br />

Ms. Karen F. Nanney<br />

Dr. David M. Nanus<br />

Mr. Steve Napleton<br />

Makarushka Napp<br />

Ms. Joanne Nasuti<br />

Dr. Carl F. Nathan<br />

National Alliance for Caregiving<br />

National Center on Education and<br />

The Economy<br />

National Philanthropic Trust<br />

Ms. Kathryn Neckerman<br />

Mrs. Fredda A. Neimark<br />

Mr. Russell Nelson<br />

Mr. John Nelson<br />

The Nelson Agency<br />

Ms. Marguerite Ness<br />

Mrs. Leonore Neto<br />

Ms. Irene B. Neuberger<br />

Ms. Rachel Neugarten<br />

Mr. Christopher Neukermans<br />

New Clay Studios, LLC<br />

New York Cardiology Associates, P.C.<br />

The New York Community Trust<br />

NYP/<strong>Weill</strong> <strong>Cornell</strong> Medical House<br />

Staff Fund<br />

Mrs. Judith B. Newbold<br />

Mrs. Virginia C. Newman<br />

Mrs. Maura O. Newman<br />

Mrs. Holly H. Newman<br />

Newman Family Foundation, Inc.,<br />

CLAT<br />

The Newman Foundation Inc.<br />

News America Marketing<br />

Mrs. Rosalina N. Nguyen<br />

Ms. Barbara O. Nichols<br />

Mr. Gene Nichols<br />

Ms. Judith Nichols<br />

Mr. Robert Nichols<br />

Nicholson & Galloway Inc.<br />

Mr. Ruben Niesvizky<br />

Mr. Henry Nigrine<br />

Ms. Kattia L. Ninahuanca<br />

Ms. Deborah B. Noble<br />

Mrs. Karin N. Noll<br />

Mr. Ronald B. Norris<br />

Northern Trust Bank, FSB<br />

Northfield Community LDC<br />

Northwestern Mutual Foundation<br />

Ms. Laura Novik<br />

Mr. and Mrs. Jerry V. Noyce<br />

Nulsen Family Trust<br />

Dr. Irwin Nydick<br />

Dr. Martin L. Nydick<br />

Ms. Carolyn Nytch<br />

NYU Occupational Therapy Students<br />

Class <strong>of</strong> 2011<br />

O<br />

Ms. Mary W. Obrien<br />

Mrs. Kimberly O. OBrien<br />

Ms. Anne K. O’Brien<br />

Oceanic Heritage Foundation<br />

Ms. Anastasija Ocheretina<br />

Mr. Stephen O’Connell<br />

Ms. Margaret O’Connor<br />

The Octoberwoman Foundation<br />

Odyssey America Reinsurance<br />

Corporation<br />

Oki Data Americas, Inc.<br />

Ambassador Herbert S. Okun<br />

Old Parish Church<br />

Kevin O’Leary<br />

Dr. Sonja K. Olsen<br />

Mr. Larry Olsen<br />

Mr. John D. Olson<br />

O’Neal, Inc.<br />

Ms. Dorothy M. O’Neil<br />

Open Society Institute<br />

Ms. Sara A. Oppenheimer<br />

Ms. Mary Opperman<br />

Ore Originals, Inc.<br />

Oregon Disaster Medical Team<br />

Mr. Douglas S. Ornstein<br />

Ms. Patricia M. Orr<br />

Ortho-McNeil Pharmaceutical<br />

Orzo Kitchen and Wine Bar, Inc.<br />

Ms. June Osborn<br />

Ms. Marcia A. Osgood<br />

Mr. Leif Ostberg<br />

OTR Global Trading<br />

Per Kristian Ottestad<br />

Our Savior Lutheran Church<br />

Carmen Oveissi<br />

Ms. Mary Owens<br />

Mr. Jerry W. Owens<br />

Ms. Donna Owings<br />

Mr. Patrick C. Oxford<br />

P<br />

P. S. 183 PTA<br />

P.S. 183 Robert Louis<br />

Stevenson<br />

Mr. Sabino S. Pace<br />

Pacific Home Studio, Inc.<br />

Meera Pahuja<br />

Ms. Iris T. Palley<br />

Dr. Lawrence G. Palmer<br />

Panwy Foundation, Inc.<br />

Ms. Mary Pao<br />

Mr. Raymond Parello<br />

Ms. Susan Parish<br />

Mrs. Sun O. Park<br />

Park 55 Medical Associates, PC<br />

Park East Cardiology Associate, PC<br />

Parker Lepla, Inc.<br />

Mrs. Ellen H. Parrill<br />

Mrs. Barbara J. Parsons<br />

Mr. Michael Partridge<br />

130 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 131


2010 Donors continued<br />

Mrs. Roya Pasqualone<br />

Mr. George O. Pastor<br />

Ms. Patricia Paszamant<br />

Ms. Binny Patel<br />

Mr. Walter J. Patrick<br />

Ms. Tiffany Patterson<br />

Dr. Austin M. Pattner<br />

Patton Boggs, LLP<br />

Paw Paw Public Schools<br />

Mrs. Elizabeth A. Peck<br />

Dr. Mark S. Pecker<br />

Ms. Sylvia Pecker<br />

Ms. Rachel L. Pecker<br />

Mr. Creighton H. Peet<br />

Ms. Alice N. Pell<br />

Ms. Kathryn Pellegrino<br />

Ms. Vita L. Pellettieri<br />

Ms. Rosana Pellizzari<br />

Ms. Paula Pelosi<br />

Pencil Portraits<br />

Ms. Jane Pepper<br />

Mr. Paul Peretz<br />

Mr. Lewis Perin<br />

Perkin Fund<br />

Dr. Francis S. Perrone<br />

Mr. Anthony Perrotta<br />

Ms. Lisa Perry<br />

Ms. Gilda F. Pervin<br />

Mr. Seymour Pestronk<br />

Peter M. Sacerdote Foundation<br />

Mr. Timothy R. Peters<br />

Ms. Sue Peterson<br />

Mr. Eric Petrone<br />

The Pfizer Foundation, Inc.<br />

Ms. Kathleen M. Philbin<br />

Ms. Charlotte Phillips<br />

Perry Phipps<br />

Mr. Adhuna Phogat<br />

Physicians’ Education Resource<br />

Group, LP<br />

Mrs. Sylvie Piccin<br />

Mrs. Karol Pick<br />

Ms. Jacklyn Pierce<br />

Ms. Lynda Pierini<br />

The Pierre F. Simon Charitable Trust<br />

Mr. Andrew G. Pietrini<br />

Ms. Lynn Pike<br />

Mr. and Mrs. Stephen Platt<br />

Mr. Adam Platt<br />

Playa Rienta Property Owners<br />

Association, Inc.<br />

Mr. Malcolm Plessis<br />

Mr. Jacob Plummer<br />

Ms. Abigail Pogrebin<br />

Ms. Miriam Pokorski<br />

Ms. Tara Polen<br />

Mr. Douglas M. Polley<br />

Ms. Michele Popadynec<br />

Mr. Edward K. Portn<strong>of</strong><br />

Ms. Patricia Posner<br />

The Posner Foundation, Inc.<br />

Mr. and Mrs. Robert M. Poss<br />

Ms. Diane Postoian<br />

Mr. John Pototsky<br />

Mrs. Paula M. Potter<br />

Ms. Nicholas Potter<br />

Ms. Terri L. Powers<br />

Mr. Pablo Pozo<br />

Prager Family Charitable Trust<br />

Dr. Elizabeth M. Prasad<br />

Ms. Ruth Prenner<br />

Presbyterian Church in Norwood<br />

Dr. R. A. Rees Pritchett<br />

Prostate Cancer Foundation<br />

Protestant Cooperative Ministry<br />

Mr. Milton Psaty<br />

Psychists Inc.<br />

Mr. Andrew Pugliese<br />

Mr. Yoram Puius<br />

Mrs. Lynn C. Purdum<br />

Ms. Eileen Puterski<br />

Mr. Robert W. Pyne<br />

Ms. Stephanie Pyonteck<br />

Q<br />

Ms. Laura A. Quinn<br />

Ms. Patricia Quinn<br />

Mrs. Amanda J. Quinton<br />

R<br />

The Rachel Foundation<br />

Mrs. Harriet Radar<br />

Mr. John D. Radice<br />

Dr. James J. Rahal, Jr.<br />

Dr. Barrie L. Raik<br />

Mrs. Joan Raines<br />

Mr. Atma Ram<br />

Ms. Christiane A. Ramirez<br />

T. Rampesaud<br />

Ranni-Gilbert Agency, Inc.<br />

Mr. David Ranz<br />

Mr. Edward J. Rappa<br />

Ms. Lisa Rasmussen<br />

Ms. Kathleen M. Rasmussen<br />

Mr. Mayur Rastogi<br />

Mr. Michael H. Ratner<br />

Mr. Norman D. Rau<br />

The Ravenel and Elizabeth Curry<br />

Foundation<br />

Raymond Schinazi Family<br />

Foundation, Inc.<br />

Ms. Sarah Read<br />

Ms. Betty Reba<br />

Mr. Gabriel Rebick<br />

Ms. Gloria Rebovich<br />

Red Ribbon Foundation<br />

Ms. Pramela Reddi<br />

Karin Redmond<br />

Sarath Rednam<br />

Mr. Thomas Reed<br />

Mr. Jon Reed<br />

Mr. Ronald H. Reede<br />

Mr. John R. Reese<br />

Dr. Bonnie S. Reichman<br />

Ms. Carolyn A. Reid<br />

Dr. Marcus M. Reidenberg<br />

Mrs. Linda Reifschneider<br />

Dr. Brendan M. Reilly<br />

Mrs. Judith M. Reilly<br />

Mr. Philip R. Reilly<br />

Ms. Mary C. Reiser<br />

Mrs. Gail M. Reiss<br />

Ms. Stacey Reiss<br />

Ms. Stephanie Reit<br />

Mr. Paul Reitemier<br />

Religious Society <strong>of</strong> Friends<br />

Mrs. Joanne E. Renna<br />

Ms. Susan Reph<br />

Dr. Gene D. Resnick<br />

Mr. Peter G. Restler<br />

Mrs. Robin E. Rex<br />

Youssef Rezk<br />

Mr. and Mrs. Richard Riccardi<br />

Richard & Priscilla M. Schmeelk<br />

Foundation<br />

Mrs. Sheila R. Richman<br />

Mr. James B. Rickert<br />

Mr. Thomas J. Rietano, III<br />

Ms. Laura Riihimaki<br />

Mr. Lee W. Riley<br />

Mrs. Dorothy W. Rinaldo<br />

Ms. Adrienne Ri<strong>of</strong>rio<br />

Ms. Lisa Ripperger<br />

Rita J. & Stanley H. Kaplan Family<br />

Foundation<br />

Mr. Charles A. Rittenour<br />

Rivermont Collegiate<br />

Ms. Carol R. Roaman<br />

Robert W. Baird and Company, Inc.<br />

Ms. Jill A. Roberts<br />

Mr. David Robertshaw<br />

Mr. Michael Robertson<br />

Dr. Rose Robertson<br />

The Robertson Foundation<br />

Detra K. Robinson<br />

Raime Robinson<br />

Mrs. Jacqueline J. Robinson<br />

Mrs. Beatriz Rocha<br />

Mr. Paul T. Rock<br />

Rodemeyer Realty<br />

Dr. Scott A. Rodeo<br />

Ms. Marie-Yves C. Rodnez<br />

Mr. William Rodriguez<br />

Ms. Valentina M. Rodriguez<br />

Ms. Anita K. Roe<br />

Roger Weiss Family Foundation<br />

Mr. Peter Rogers<br />

Rogosin Institute<br />

Mr. Chris Roh<br />

Dr. Mary J. Roman<br />

Mr. Bryan S. Romano<br />

Ms. Maria E. Romero<br />

Mrs. Rebecca L. Romero<br />

Mr.Jack Romita, Jr.<br />

Mr. and Mrs. Richard Roob<br />

Ms. Marie Roos<br />

Mr. Arnold S. Root<br />

Ms. Elizabeth Rose<br />

Rosemont College<br />

Mrs. Joan S. Rosen<br />

Ms. Lynne Rosenbaum<br />

Mrs. Aviva Rosenberg<br />

Dr. Benjamin A. Rosenberg<br />

Dr. Howard Rosenberg<br />

Dr. Isadore Rosenfeld<br />

Mr. Jack E. Rosenfeld<br />

Dr. Ralph E. Rosenberg<br />

Mr. Mordecai Rosenfeld<br />

Rosenfeld Heart Foundation<br />

Mrs. Kimberly M. Rosenstock<br />

Ms. Lisa Rosenthal<br />

Mr. Philip Ross<br />

Dr. Albert M. Ross<br />

Ms. Rita Rossi-Foulkes<br />

Ms. Johanna Rossman<br />

Mr. Franklin M. Roth<br />

Ms. Carrie Rothfeld<br />

Ms. Felice Rovelli<br />

Ms. Patricia Rowe<br />

Ms. Ellin Royds<br />

Dr. Jia Ruan<br />

Mr. Mark Rubin<br />

Ms. Nancy E. Rubinstein<br />

Mr. Jack Rudin<br />

Ms. Susan M. Rudin<br />

Dr. Joseph T. Ruggiero<br />

Mr. Charles T. Russell, III<br />

Ruth and Samuel J. Rosenwasser<br />

Charitable Trust<br />

Ruth C. Rosen Trust<br />

The Ruth Stanton Foundation<br />

Mr. Andrew Ryan<br />

Mr. Michael S. Ryan<br />

Mr. Bradley Rymph<br />

S<br />

S. Forest Company, Inc.<br />

Mr. Daniel Sachar<br />

Mr. William Sachau<br />

Mrs. Sara Sachs<br />

Mrs. Toby C. Sacks<br />

Mr. Bruno Sadum<br />

Mr. Robert Salant<br />

Mr. Steven Salant<br />

Ms. Nadya Salcedo<br />

Salix Pharmacueticals, Inc.<br />

Mr. Alberto Salvo<br />

Mr. Robert J. Salzman<br />

Samourkas Foundation <strong>of</strong> New York<br />

Samuel I. Newhouse Foundation, Inc.<br />

Ms. Melanie Samuels<br />

Dr. Ronald C. Samuels<br />

San Mateo City Employees Federal<br />

Credit Union<br />

Ms. Joanne Sanantonio<br />

Dr. Abraham Sanders<br />

Mr. Joel S. Sandler<br />

Ms. Joanne Santangelo<br />

Dr. Anthony G. Santomauro<br />

Ms. Elsa A. Santos<br />

Mr. Michael B. Sapik<br />

Sarah de C. Ruth Trust<br />

Mr. Giorgio Sarne<br />

Sass Foundation for Medical<br />

Research, Inc.<br />

Ms. Beryl E. Satter<br />

Saturday Knight Ltd.<br />

Mrs. Susan B. Saunders<br />

Ms. Patricia A. Saunders<br />

Mr. Ernest Schaal<br />

Dr. Bruce R. Schackman<br />

Ms. Dulcie L. Schackman<br />

Mr. Jeffrey S. Schackner<br />

Mrs. Gloria Schackner<br />

Mrs. Pauline S. Schafer<br />

Ms. Pamela Schaff<br />

Ms. Miriam Schatz<br />

Dr. Ronald J. Scheff<br />

Mrs. Ernestyna Schenker<br />

Mr. Albert Schlesinger<br />

Mrs. Phyllis M. Schlisserman<br />

Mrs. Francesca E. Schlueter<br />

Ms. Terri Schmidt<br />

Dr. Bryan J. Schneider<br />

Mr. and Mrs. David Z. Schneider<br />

Ms. Jeanne Schoenfelder<br />

Mr. Robert Schonberg<br />

Dr. Ann W. Schongalla<br />

Ms. Carrie Schonwald<br />

Mr. Hans Schreuder<br />

Ms. Audrey N. Schuetz<br />

Ms. Allison R. Schulman<br />

Dr. Leonard H. Schuyler<br />

Schwab Charitable Fund<br />

Mr. Jay M. Schwamm<br />

Ms. Susannah Schwarcz<br />

Mr. Max J. Schwartz<br />

Mr. and Mrs. Robert N. Schwartz<br />

Mrs. Elizabeth M. Schwartz<br />

Mr. Stephen J. Schwartz<br />

Dr. Kenneth V. Schwartz<br />

Mr. David Schwartz<br />

Dr. and Mrs. Sergio Schwartzmann<br />

Ms. Diana Schwatka<br />

Mrs. Judith S. Schweiger<br />

Gilead Sciences<br />

Mr. Eriberto R. Scocimara<br />

Mr. Jason Scully-Clemmons<br />

Mr. David Seal<br />

Sealcoating, Inc.<br />

Ms. Cynthia Sears<br />

Mrs. Lucille Sedgeley<br />

Seevers Family Foundation<br />

Ms. Mary Seidel<br />

Mr. Charles B. Selden<br />

Ms. Naomi O. Seligman<br />

Mr. Aydin Senkut<br />

Ms. Lisa Senzel<br />

Ms. Susan B. Sepelak<br />

Mrs. Carole M. Sergent<br />

Ms. Barbara Serota<br />

Seth Sprague Educational and<br />

Charitable Foundation<br />

Mr. James Sethna<br />

Ms. Audrey L. Sevin<br />

Mr. Richard Seymour<br />

Ms. Caroline Seymour<br />

Ms. Monika Shah<br />

Mr. Sudhin Shah<br />

Mr. David M. Shandel<br />

Dr. David A. Shapiro<br />

Mrs. Alice L. Shapiro<br />

Mr. Rodney Sharkey<br />

Mr. Manish Sharma<br />

The Shaw Family Endowment Fund<br />

Ms. Stacey Shedden<br />

Mr. John P. Sheganoski<br />

Ms. Lorraine Shemesh<br />

Mr. Ty S. Shen<br />

Dr. Raymond L. Sherman<br />

Dr. Eric J. Sherman<br />

Dr. Melvin R. Shevach<br />

Mrs. Caroline Shiboski<br />

Shickman Family Foundation<br />

Ms. Naomi Shike<br />

Ms. Nina Shilling<br />

Dr. Rony Y. Shimony<br />

Shipley School<br />

Shirley D. Harris Trust<br />

Ms. Nancy Shopkorn<br />

Ms. Nancy G. Shor<br />

Dr. Tsiporah Shore<br />

Dr. Morris A. Shor<strong>of</strong>sky<br />

Ms. Tanaya Shree<br />

Ms. Karen D. Shugart<br />

Ms. Martha Shuman<br />

Ms. Carrie Shumway<br />

Ms. Carrie Siegel<br />

Dr. Lawrence Siegel<br />

Dr. Eugenia L. Siegler<br />

Ms. Angela L. Sierra<br />

Mr. M. S. Silbermann<br />

Silbert Charitable Fund<br />

Dr. Alfred M. Sils<br />

Mrs. Adrienne Silver<br />

Mr. Martin Silver<br />

Silverberg Family Foundation, Inc.<br />

Ms. Helene Silverman<br />

Mr. Carl Simons<br />

Ms. Kenishana Simpson<br />

Ms. Jeanie Sims<br />

Ms. Deena A. Singer<br />

Ms. Kavita Singh<br />

Ms. Garima Singh<br />

Ms. Althea Sircar<br />

Mr. Charles Sirey<br />

Mr. Roman Sivion<br />

Skadden, Arps, Slate, Meagher &<br />

Flom, LLP<br />

Ms. Linda Sklaren<br />

Ms. Rolly L. Slatt<br />

Mr. Alexander Slemrod<br />

Ms. Elaine Slocum<br />

Mr. David Slottje<br />

Ms. Dina B. Smallman<br />

Ms. Brooke N. Smith<br />

Mrs. Dina Smith<br />

Dr. James P. Smith<br />

Mrs. Janet S. Smith<br />

Mrs. Lynn B. Smith<br />

Mr. Malcolm A. Smith<br />

Ms. Margaret Smith<br />

Ms. Marta Smith<br />

Ms. Nancy Smith<br />

Dr. Paul T. Smith<br />

Howard G. Smith Trust<br />

Ms. Ann Snead<br />

Mr. George B. Snell<br />

Mr. Daniel Soba<br />

Social & Scientific Systems, Inc.<br />

Society for Edible Horticulture<br />

Ms. Nina Solenski<br />

Mr. Arnold R. Sollar<br />

The Sollar Foundation, Inc.<br />

Ms. Kathleen R. Somers<br />

Ms. Susan L. Sommer<br />

Mrs. Cindy L. Soper<br />

Sound Shore Cardiology, PC<br />

Southern Development<br />

Ms. Mavis Spectorman<br />

Ms. Heathir M. Speet<br />

Mr. James W. Spencer<br />

Ms. Emily A. Spengler<br />

Speyer Legacy School<br />

Mrs. Ann S. Spindel<br />

Ms. Michele Spring<br />

Spring OB/GYN, P.C.<br />

Ms. Valerie Spruell<br />

Mr. John W. Spurdle, Jr.<br />

Mrs. Amanada Spyrou<br />

Mr. Ragini Srinivasan<br />

St. John’s PTO<br />

St. Paul’s Radiology Associates<br />

Mr. Edwin Stack<br />

Mr. Peter Staley<br />

Mrs. Jodi Starr<br />

Ms. Marina Stasenko<br />

Mrs. Joan Stasior<br />

Mrs. Shelly D. Staudenmeir<br />

Ms. Ellen Stebbins<br />

Mr. Peter Stein<br />

Mr. Robert Stein<br />

Dr. Charles R. Steinberg<br />

Mr. Frank Stella<br />

Ms. Mary Stengel<br />

Ms. Darcy G. Stephens<br />

Mr. Timothy R. Sterling<br />

Mrs. Joan J. Sterling<br />

Sterne Agee & Leach, Inc.<br />

Syman Stevens<br />

Mr. Mark Stitzer<br />

Ms. Julie St<strong>of</strong>el<br />

Mr. and Mrs. Fred C. Stoll<br />

Mr. Andrew D. Stone<br />

Ms. Patricia Stone<br />

Mr. James Storelli<br />

Dr. Carol L. Storey-Johnson<br />

Ms. Sarah L. Stout<br />

Ms. Geraldine Stover<br />

Dr. Adam R. Stracher<br />

Ms. Phyllis Strauss<br />

Mrs. Nancy A. Streeter<br />

Ms. Jane M. Stubenbord<br />

Ms. Heidi Stuhlmann<br />

Ms. Paola Styron<br />

Ms. Susanna Styron<br />

Ms. Patricia C. Sullivan<br />

Dr. John F. Sullivan<br />

Ms. Susan Sullivan<br />

Mrs. Virginia M. Sullivan<br />

The Summerhill Foundation<br />

Sunil Paul and Michelle Odom<br />

Foundation<br />

Sunnyside Kiwanis Foundation, Inc.<br />

Dr. Peggy Supple<br />

Susan D. Camilli Foundation<br />

Col. and Mrs. Anthony Suso<br />

Dr. Manikkam Suthanthiran<br />

Mrs. Myra Sutro<br />

Mr. Jack R. Swain, III<br />

Ms. Amanda Swan<br />

Ms. Susan Swindells<br />

Mr. Chris Syphers<br />

Dr. Andrew J. Szabo<br />

T<br />

T. Rowe Price Program for<br />

Charitable Giving<br />

Dr. Chin Tang<br />

Mr. Delbert Tanner<br />

Ms. Kristina Tarczy-Hornoch<br />

Mrs. Patricia A. Tarpey<br />

Mr. David Tarr<br />

Mr. Suresh S. Tate<br />

Tate Transport Corporation<br />

Mrs. Marcia Tatrallyay<br />

Ms. Sabra Tatum<br />

Mr. Paul J. Taubman<br />

Mr. Robert W. Taylor<br />

Ms. Rachelle Taylor<br />

Mrs. Ruth Taylor<br />

Mrs. Anne Alexis Cote Taylor<br />

Ms. June Teal<br />

Mr. Thomas J. Templeton<br />

Ms. Karen Tenser<br />

Mrs. Carol M. Tepper<br />

Ms. Kathryn Terry<br />

Ms. Danielle J. Tesoriero<br />

132 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 133


2010 Donors continued<br />

Mrs. Elizabeth The<strong>of</strong>anidis<br />

Mr. George E. Thompson<br />

Ms. Stacy Thompson<br />

Mrs. Victoria A. Thorman<br />

Mr. John Thorne<br />

Ms. Katherine Thurer<br />

The Tianaderrah Foundation<br />

Mr. Jerome Tiger<br />

Ms. Anna Tikhomirova<br />

Ms. Maryellen Tipton<br />

Mr. Jeff Titherington<br />

Mrs. Vanessa A. Toevs<br />

Ms. Doris Tolins<br />

Ms. Lucy Tompkins<br />

Mr. Jeffrey T. Totaro<br />

Mrs. Aspasia D. Trakis<br />

Ms. Mindy Tran<br />

Mr. and Mrs. Jeffrey D. Tranen<br />

Transport Consultants International, Inc.<br />

Mr. Seran Trehan<br />

Mr. Vincent A. Tria, Jr.<br />

Trident Maritime Agency, Inc.<br />

Trinity Baptist Church<br />

Mr. Joseph Trotta<br />

Mr. Kent G. Troup<br />

Ms. Jennifer R. Truelove Truist<br />

Ms. Jennifer Truman<br />

Honorable Maryanne Trump Barry<br />

Ms. Paula Trushin<br />

Ms. Linnet R. Tse<br />

Mr. Wei Tseng<br />

Mr. and Mrs. Jun Tsusaka<br />

Mrs. Marian M. Tsutsui<br />

Mrs. Elizabeth Tulchin<br />

Srilaxmi Tumuluri<br />

Dr. Judy Tung<br />

Mr. Nicolas Turek<br />

Dr. Meredith L. Turetz<br />

Mr. Gary W. Turner<br />

Mr. Jeffrey Turner<br />

U<br />

UCB, Inc.<br />

Union for Reform Judaism<br />

Universal City Studios, LLLP<br />

University Montessori School<br />

University <strong>of</strong> Minnesota Alumni<br />

Association<br />

University <strong>of</strong> Virginia Alumni<br />

Association<br />

University <strong>of</strong> Virginia Fund<br />

Unknown<br />

Mr. Michael Urkowitz<br />

The U.S. Charitable Gift Trust<br />

Mr. Manuel Utset<br />

V<br />

Ms. Jessica Vacanti<br />

Dr. Linda T. Vahdat-Kummen<br />

Ms. Jennifer Vale<br />

Mr. James Valentino<br />

Van Ameringen Foundation<br />

Mr. Albert W. Van Ness, Jr.<br />

Ms. Sarah Vanderbilt<br />

Mr. Peter Vando<br />

The Vanguard Charitable Endowment<br />

Program<br />

Mr. John L. Vanosdall<br />

Mr. Joseph Varano<br />

Mr. Frank P. Vella<br />

Ms. Sharon Verduzco<br />

Verizon Foundation<br />

Dr. Sten H. Vermund<br />

Mrs. Mary J. Vinci<br />

Vital Projects Fund, Inc.<br />

Vladimir & Araxia Buckhantz<br />

Foundation<br />

Mr. Robert Vollrath<br />

Mr. Charles Vorkas<br />

W<br />

The W. O’Neil Foundation<br />

Ms. Mary Wachter<br />

Ms. Wendy Wagner<br />

Mr. Brian Wahl<br />

Mr. Laurence Walcott<br />

Mr. Scott L. Walker<br />

Ms. Joan Walsh<br />

Mr. Edmund Walsh<br />

Mr. Michael Walsh<br />

Ms. Cora M. Walsh<br />

Mrs. Harriet Walters<br />

Mr. Gregory S. Wands<br />

Mr. Chengbing Wang<br />

Ms. Suzanne Wapner<br />

Ms. Kristin Warfield<br />

Mr. Stephen Warnke<br />

Ms. Robin Warren<br />

Dr. Craig H. Warschauer<br />

Ms. Carol Warshawsky<br />

Mr. Jonathan Washburn<br />

Washington Speakers Bureau<br />

Ms. Nora Wasserman<br />

Mr. Ben Wasserman<br />

The Waterfall Family Foundation<br />

B. Lynn Watson<br />

The Wayen Charitable Foundation<br />

Mr. Robert Weaver<br />

WebMD, LLC<br />

Dr. Arnold L. Weg<br />

Mrs. Marie B. Weigl<br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College-Qatar<br />

Mrs. Susan R. <strong>Weill</strong>er<br />

Mr. Ethan Weinberg<br />

Dr. Alan M. Weinstein<br />

Dr. Daniel E. Weinstein<br />

Mr. Mark S. Weinstein<br />

Mr. Marvin Weinstock<br />

Ms. Selma Weintraub<br />

Mr. I. Daniel Weisberg<br />

Ms. Joan Weisberg<br />

Mrs. Bertha Weiser<br />

Mr. Mark Weisman<br />

Mr. Warren A. Weiss<br />

Ms. Dana A. Weiss<br />

Mrs. Joan S. Weissman<br />

Mrs. Helene M. Weld<br />

Mrs. Jill Wellenbach<br />

Ms. Marjorie Weller<br />

Wellington Management<br />

Company, LLP<br />

Wells Fargo Foundation<br />

Mr. Jared Wels<br />

Ms. Sarah West<br />

Westside Cardiology, PC<br />

Ms. Alexis Wheeler<br />

Ms. Amber L. Wheeler<br />

Ms. Rebecca A. Whipple<br />

Dr. Judith Whitcomb<br />

Mrs. Nieva S. White<br />

Whitehead Foundation<br />

Mr. Kenneth L. Whitley<br />

Mrs. Gail Wichler<br />

Mr. Mitch Wiedemann<br />

Mr. Eric S. Wiemann<br />

Mr. Howard L. Wiener<br />

Mr. Barrie A. Wigmore<br />

Mr. David Wilde<br />

Mr. Carlton Wilde<br />

Dr. Henry D. Wilde, Jr.<br />

Ms. Ann Wilde<br />

Mr. James Wildman<br />

Mr. Stephen G. Wilkerson<br />

Mr. Timothy J. Wilkin<br />

Mr. Jonathan Will<br />

The William & Mary Greve<br />

Foundation, Inc.<br />

William Brown Foundation<br />

The William P. Goldman & Brothers<br />

Foundation, Inc.<br />

William T. Foley Foundation<br />

Ms. Catherine Williams<br />

Ms. Evette Williams<br />

Mr. Keith Williams<br />

Mrs. Nitsa C. Williams<br />

Mr. Raymond A. Williams<br />

Willis H. Flick Revocable Trust<br />

Mr. David R. Wilson<br />

Ms. Della Wilson<br />

Mr. Gregory Wilson<br />

Ms. Judith B. Wilson<br />

Ms. Kathryn Wilson<br />

Ms. Teresa Wilson<br />

Ms. Elizabeth A. Wilson-Anstey<br />

Ms. Belinda Winn<br />

Winston Foundation, Inc.<br />

Mr. Andrew Winston-Brown<br />

Ms. Ruth Wintobrown<br />

Dr. Gilbert J. Wise<br />

Mr. Lawrence Wit<br />

Dr. James F. Wittmer<br />

Ms. Racquel Wohlers<br />

Dr. David J. Wolf<br />

Wolf Maryles & Associates, LLC<br />

Ms. Adele Wolinsky<br />

Mr. Peter Wolk<br />

Mrs. Jodi Wolkind<br />

Mrs. Julie Wolman<br />

Mr. Brian Wong<br />

Mr. Hon K. Wong<br />

Mr. Lawrence Woo<br />

Mr. Gary Wood<br />

Mr. Jeffrey Wood<br />

Ms. Barbara Z. Woodring<br />

Mr. Gary Woodring<br />

Ms. Beth Woods<br />

Mrs. Sheila Woods-Romano<br />

Woodward Gallery<br />

Elaine Worcester<br />

Dr. Stefan Worgall<br />

Mr. John Woschinko<br />

Dr. Peter F. Wright<br />

A. Danielle Wright<br />

Mr. Mark Wright<br />

Mr. C. J. Wright<br />

Peng Wu<br />

X<br />

Yifan Xu<br />

Y<br />

Y.C. Ho/Helen and Michael Chiang<br />

Foundation<br />

Ms. Luise Yacono<br />

Yankee Barn Homes, Inc.<br />

Mr. Mineo Yasufuku<br />

Ms. Sarah Yee<br />

Ms. Min-Jean Yin<br />

Dr. Cecelia J. Yoon<br />

Ms. Christina M. Young<br />

Dr. Charles S. Young<br />

Ms. Lunna Yu<br />

Mr. Nick Yuran<br />

Z<br />

Mr. William D. Zabel<br />

Mr. Thaddeus Zelski<br />

Ms. Xue H. Zhu<br />

Ms. Marilyn Ziment<br />

Mr. Scott M. Zimmerman<br />

Mr. James D. Zirin<br />

Mr. Martin R. Zonnenberg<br />

Zoom Information, Inc.<br />

Ms. Eileen Zore<br />

Dr. Michael A. Zullo<br />

Ms. Robin F. Zwerling<br />

Mr. Edward F. Zwick<br />

If you have any questions<br />

or corrections concerning<br />

these listings, please contact<br />

the Development Office at<br />

(800) 345-3015. We regret<br />

any errors or omissions.<br />

134 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2011 135


Chairman’s Office<br />

Chairman<br />

Andrew I. Schafer, MD<br />

Tel: (212) 746-4720<br />

Executive Vice Chair for Clinical Affairs<br />

Brendan M. Reilly, MD<br />

Tel: (212) 746-6420<br />

Administrative Manager<br />

Beverly Borg<br />

Tel: (212) 746-4271<br />

Administration<br />

Chief Administrative Officer & Vice Chair<br />

for Business Affairs<br />

Tipton (Tip) Ford<br />

Tel: (212) 746-4271<br />

Senior Administrator<br />

Nancy Bennett<br />

Tel: (212) 746-4007<br />

Associate Administrator<br />

Peter Kam<br />

Tel: (212) 746-4007<br />

Senior Administrative Manager<br />

Thu Trang Du<br />

Tel: (212) 746-4371<br />

Residency Office<br />

Vice Chair for Education<br />

Director <strong>of</strong> the Internal <strong>Medicine</strong><br />

Residency Program<br />

Lia Logio, MD<br />

Tel: (212) 746-4749<br />

Residency Administrator<br />

Jeanne Macaluso<br />

Tel: (212) 746-4749<br />

Divisional Offices<br />

Cardiology<br />

Bruce B. Lerman, MD, Chief<br />

Ann Matier, Administrator<br />

Tel: (212) 746-2176<br />

Clinical Epidemiology and Evaluative<br />

Sciences Research<br />

Mary E. Charlson, MD, Chief<br />

Suzan Toro, Administrator<br />

Tel: (212) 746-1606<br />

Clinical Pharmacology<br />

Marcus M. Reidenberg, MD, Chief<br />

Tel: (212) 746-6227<br />

Emergency <strong>Medicine</strong><br />

Neal E. Flomenbaum, MD, Chief<br />

Georgia Rose, Administrator<br />

Tel: (212) 746-0780<br />

Endocrinology, Diabetes & Metabolism<br />

Julianne Imperato-McGinley, MD, Chief<br />

Debbie Dimanche, Administrator<br />

Tel: (212) 746-1503<br />

Gastroenterology & Hepatology<br />

Ira M. Jacobson, MD, Chief<br />

David Berger, Administrator<br />

Tel: (646) 962-4778<br />

Geriatrics & Gerontology<br />

Ronald D. Adelman, MD, Co-Chief<br />

Mark S. Lachs, MD, MPH, Co-Chief<br />

Mary Anderson, Administrator<br />

Tel: (212) 746-1733<br />

Hematology and Medical Oncology<br />

Barbara L. Hempstead, MD, PhD, Co-Chief<br />

David M. Nanus, MD, Co-Chief<br />

Paula Goldstein, Administrator<br />

Tel: (212) 746-4550<br />

Hospital <strong>Medicine</strong><br />

Arthur T. Evans, MD, MPH, Chief<br />

Vice Chair <strong>of</strong> Faculty Development<br />

Mary Elizabeth Kelser, Administrator<br />

Tel: (212) 746-4910<br />

Immunology<br />

Kendall A. Smith, MD, Chief<br />

Nadine McLaughlin, Administrator<br />

Tel: (646) 962-8170<br />

Infectious Diseases<br />

Roy M. Gulick, MD, MPH, Chief<br />

Eduardo Baez, Administrator<br />

Tel: (212) 746-4914<br />

Iris Cantor Women’s Health Center<br />

Orli R. Etingin, MD, Director<br />

D. Anne Stewart, Administrator<br />

Tel: (212) 821-0558<br />

Medical Ethics<br />

Joseph J. Fins, MD, Chief<br />

Cathleen Acres, Administrator<br />

Tel: (212) 746-4246<br />

Nephrology and Hypertension<br />

Manikkam Suthanthiran, MD, Chief<br />

Anita Mesi, Administrator<br />

Tel: (212) 746-4430<br />

Pulmonary & Critical Care <strong>Medicine</strong><br />

Ronald G. Crystal, MD, Chief<br />

Malika McKenzie, Administrator<br />

Tel: (646) 962-5569<br />

Rheumatology<br />

Mary K. Crow, MD, Chief<br />

Laughlin Rice, Administrator<br />

Tel: (212) 606-1845<br />

<strong>Weill</strong> <strong>Cornell</strong> Internal <strong>Medicine</strong><br />

Associates<br />

Judy Tung, MD, Medical Director<br />

ThuTrang Du, Faculty Administrator<br />

Tel: (212) 746-4371<br />

Managing Editor-Writer<br />

Suzanne Ross<br />

<strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

Design<br />

Sundberg Design, Inc.<br />

Photography<br />

Roger Tully<br />

Roger Tully Productions<br />

Contributing Photography<br />

Dr. Jennifer Downs<br />

Robert Essel<br />

Bud Glick<br />

Rebecca Heidkamp, PhD<br />

Patricia Kuharic<br />

Lt. Vincent Mullen<br />

Amelia Panico<br />

Dr. Robert Peck<br />

Special Thanks to:<br />

Jessica Arnau<br />

Dr. Graeme Bailey<br />

Doug Banquer<br />

Herbert Barnett<br />

Beverly Borg<br />

Talley Henning Brown<br />

Nicholas Chin<br />

Brian DeMello<br />

Division Administrators<br />

Thu Trang Du<br />

Dr. Evi Giannakakou<br />

Al Greenberg<br />

Alison Holzberg<br />

Dr. Warren Johnson, Jr.<br />

Peter Kam<br />

Dr. Adam Law<br />

Jeanne Macaluso<br />

Lt. Vincent Mullen<br />

Ayad Nagi<br />

Pete Pizzuti<br />

Dr. Charles Rice<br />

Leonard Sadosky, PhD<br />

Dr. Andrew I. Schafer<br />

Silva Sergenian<br />

Greg Sundberg<br />

Nadine Sylvain<br />

Roger Tully<br />

Karen Wong<br />

Maria Wright<br />

Dr. Christini’s Lab Members<br />

Dr. Hempstead’s Lab Members<br />

Dr. Suthanthiran’s Lab Members<br />

136 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

Annual Report 2011 137


102 <strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

NewYork-Presbyterian Hospital/<br />

<strong>Weill</strong> <strong>Cornell</strong> Medical College<br />

<strong>Department</strong> <strong>of</strong> <strong>Medicine</strong><br />

525 East 68th Street, Box 130<br />

New York, NY 10065<br />

www.cornellmedicine.com<br />

<strong>Department</strong> <strong>of</strong> <strong>Medicine</strong> Annual Report 2010 <strong>Weill</strong> <strong>Cornell</strong> Medical College NewYork-Presbyterian Hospital

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