RegeneRative mediCine - ALM Events

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Welcome Dear Colleague: The promise of stem cells & regenerative medicine discoveries and their potential to transform the treatment of disease, continues to drive biological research and technology development in the life sciences. The fact that analysts predict that a market based on stem cell therapies could grow anywhere from $10-30 billion by 2010 makes it crucial for us to gather and discuss the research and commercialization activities currently being conducted by academia and industry. The field of regenerative medicine is surrounded by hype, but successful commercialization will depend on careful analysis of business strategies that can deliver hope to patients. Please join us in Pittsburgh, Pennsylvania, October 16-17, 2006 for the 6th Annual Stem Cells & Regenerative Medicine meeting. This forum is the perfect setting for thought leaders in regenerative medicine to convene and share critical perspectives on the current status and future of stem cell research and regenerative medicine. This meeting is designed to promote interactions that will ultimately result in the acceleration of scientific discovery and the development of new technologies, in the end benefiting patients worldwide. We look forward to being your hosts in Pittsburgh for the second consecutive year. Pittsburgh’s strengths in the areas of transplantation, tissue engineering and stem cell research continue to make it a great location for us to come together for the advancement of regenerative medicine. Regards, Dr. Doros Platika, Conference Co-Chair, President & CEO The Pittsburgh Life Sciences Greenhouse 5 CALL: (800) 599.4950 (212) 967.0095 8:30 - 5:30 Eastern Time Monday – Friday FAX: (212) 967.8021 MAIL: Return Registration Form to: Strategic Research Institute 333 Seventh Avenue, 9th Floor New York, NY 10001 E-MAIL: info@srinstitute.com WEB: www.srinstitute.com/stemcells Dr. Alan Russell, Conference Co-Chair, Director, McGowan Institute for Regenerative Medicine (MIRM) and Executive Director, The Pittsburgh Tissue Engineering Initiative (PTEI) P.S. Register by September 1, 2006 and Save $300 Easy Ways To Register Group Discount: Group Discounts Available: If you send two delegates to this conference at the full registration fee, the third and subsequent delegates receive a $200 discount off the conference registration fee. PAYMENTS: $695 Academic/Government/Nonprofit; $1195 Early bird: until Friday September 1, 2006; $1495 After September 1st and before October 6th; $1595 after October 6th This includes all breakfasts, lunches, refreshments, receptions and the conference documentation workbook. Payments may be made by company check, American Express, Visa, MasterCard or Diners Club. Please make checks payable to: Strategic Research Institute L.P. and make sure to write the registrant’s name on the face of the check along with the conference code CS369. Payments are required fifteen (15) business days prior to attendance at the seminar. If payment has not been received prior to registration, a credit card hold will be required and will be processed 2 weeks following the seminar. LIMITED NUMBERS: The number of participants is limited to maximize the amount of personal involvement and feedback you receive. During this seminar, you will have the opportunity to try out techniques and take risks in a small group of your colleagues, benefiting from expert guidance throughout the day. CANCELLATIONS: All cancellations will be subject to a $227 administration fee. In order to receive a refund, your notice of cancellation must be received in writing (by letter or fax) no later than August 18, 2006. We regret that refunds Scientific Advisory Board: Gabriela Cezar, Ph.D., Associate Professor UNIVERSITY OF WISCONSIN - MADISON Karen Chandross, Ph.D., Head, Multiple Sclerosis-Regeneration/Repair Group, CNS Division AVENTIS PHARMACEUTICALS Annemarie Moseley, Ph.D., M.D. , Acting CEO, Aggregate Therapeutics Chairman, REPAIR TECHNOLOGIES Doros Platika, M.D., Ph.D, President & CEO PITTSBURGH LIFE SCIENCES GREENHOUSE Dr. Alan Russell, Conference Co-Chair, Director, McGowan Institute for Regenerative Medicine (MIRM) and Executive Director, The Pittsburgh Tissue Engineering Initiative (PTEI) Darin Weber, Ph.D., Senior Consultant BIOLOGICS CONSULTING GROUP Frequency Program: If you personally attend three Strategic Research Institute conferences in 2006 as a fee-paying delegate, you will be credited 50% off the full registration fee of third event. Please be sure to indicate that it is your third event when registering so that your invoice may be adjusted accordingly. Discounts cannot be combined. will not be issued after this date. The registration fee may be transferred to you or another member of your organization for any Strategic Research Institute conference during the next 12 months. If you plan on sending a substitution in your place, you must please notify us as soon as possible so that material and preparations can be made. In the event of a conference cancellation, Strategic Research Institute assumes no liability for non-refundable transportation costs, hotel accommodations or additional costs incurred by the registrants. SUGGESTED DRESS: Business Casual Hotel Accommodations:We have reserved a limited block of rooms with the hotel at a special discounted rate for our attendees. To secure your accommodations, please contact the hotel BY September 18th, 2006 and be sure to mention that you are a Strategic Research Institute delegate. VENUE: Renaissance Pittsburgh Hotel 107 6th Street , Pittsburgh, PA 15222 Tel: 412-562-1200 - Fax: 412-992-2010 Web: marriott.com/property/propertypage/PITBR To Register: Visit www.srinstitute.com/stemcells or Call 800-599-4950 / 212-967-0095
Monday October 16, 2006 7:15 - 8:00 Registration and Continental breakfast 8:00 - 8:15 Chair’s opening remarks Doros Platika, M.D., Ph.D., President & CEO PITTSBURGH LIFE SCIENCES GREENHOUSE Dr. Alan Russell, Conference, Co-Chair, Director McGowan Institute for Regenerative Medicine (MIRM) and Executive Director, The Pittsburgh Tissue Engineering Initiative (PTEI) Stem Cells update 8:15-9:00 Keynote Application of cellular therapy to the field of regenerative medicine is one of the most promising and exciting areas of biomedical research. Identification of new sources and types of stem cells, discovery of “additional/unexpected” differentiation pathways, along with advances in purification, culture, and tissue engineering technologies are all contributing to an explosion of research publications, initiation of clinical trials, and tremendous public interest. The talks to be presented in this meeting reflect the broad scope, the remarkable potential, and the challenges that need to be overcome before cell-based regenerative medicine can become the standard of care. Shelly Heimfeld, Ph.D., Director Cellular Therapy and Cell Processsing Facilities Associate Member, Fred Hutchinson Cancer Research Center President, the International Society of Cellular Therapy Discovery Cells 9:00 - 9:30 hESC-derived beta-islets for therapeutic intervention in diabetes Cell Therapy for the widespread treatment of diabetes is currently limited by the lack of an unlimited safe supply of islet cells and a means of delivering these cells without chronic immunosuppresion. Novocell is committed to the development of a transformational cell replacement product for the treatment of diabetes by combining a clinically relevant cell encapsulation technology with an unlimited supply of functional insulin secreting cells derived from hESCs. Current progress towards these goals will be discussed. Alan Lewis, Ph.D., President & Chief Executive Officer Novocell 9:30-10:00 Human ESC-derived cells for rescue of visual function and repair of vascular damage Embryonic stem cells promise to provide a well-characterized and reproducible source of replacement tissue for human clinical studies. Two early potential applications of this technology are the use of human embryonic stem cell (hESC)-derived retinal pigment epithelium (RPE) for the treatment of retinal degenerative diseases such as macular degeneration and retinitis pigmentosa, and the use of hESC-derived hemangioblasts for vascular restoration of organs and limbs. Recent progress using these cells to affect substantial functional and morphological rescue in animals will be discussed. Robert Lanza, M.D., Vice-President of Research and Scientific Development Advanced Cell Technology 10:00 -10:30 Bioreactor-actuated ovarian follicle maturation Chemotherapy for girls with cancer can lead to infertility later in life. Embryonic stem cell generation is dependent on a not entirely safe process for collection of oocytes from adult women. Both of these problems could be solved if it were possible, in vitro, to convert immature ovarian follicles into functional oocytes. Unfortunately, immature ovarian follicle culture results in follicle death within days let alone oocyte generation. This presentation will describe the first bioreactor that has been developed specifically for maturation of immature follicles and will discuss the results that have been obtained. The implication of the results on safe stem cell derivation will be summarized. Dr. Alan Russell, Conference, Co-Chair, Director McGowan Institute for Regenerative Medicine (MIRM) and Executive Director, The Pittsburgh Tissue Engineering Initiative (PTEI) 10:30 -11:00 Networking break & Exhibitions Discovery-Enabling materials 11:00 - 11:30 Driving Stem Cell Differentiation with a Novel High Throughput System Plasticell has developed a high throughput method for the determination of complex protocols that can direct the differentiation of embryonic stem cells. Pluripotent stem cells grown on microscopic beads (microcarriers) are shuffled through many thousands of different culture conditions, followed by phenotypic screening to identify microcarriers bearing differentiated cells. Using fluorescent labels added during the culture steps it is possible to deduce the protocols that resulted in directed differentiation. Since these are compatible with microcarriers, the process is straightforwardly scaled up for manufacturing. Yen Choo, Ph.D., Founder & CEO Plasticell 11:30 - 12:00 Chemical and Functional Genomic Approaches toward Regenerative Medicine Under conditions of trauma or disease, the adult animal is able to selectively re-activate the same developmental pathways used during embryonic development to heal and regenerate tissue. To Register: Visit www.srinstitute.com/stemcells or Call 800-599-4950 / 212-967-0095
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