What is a domain?
What is a domain?
What is a domain?
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CATH Protein Structure Classification<br />
The CATH database <strong>is</strong> a hierarchical <strong>domain</strong> classification<br />
of protein structures.<br />
C class<br />
Alpha <strong>domain</strong>, Beta <strong>domain</strong>, Alpha-Beta <strong>domain</strong> etc.<br />
A architecture<br />
Barrel, Sandwich, Propeller, Bundle etc.<br />
http://www.cathdb.info<br />
T topology (fold family)<br />
Structures are grouped into fold groups at th<strong>is</strong> level<br />
depending on both the overall shape and connectivity of the<br />
secondary structures.<br />
H homologous superfamily<br />
Th<strong>is</strong> level groups together protein <strong>domain</strong>s which are<br />
thought to share a common ancestor and can therefore be<br />
described as homologous.<br />
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