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Fall 2012/Winter 2013 Aesculapian Magazine - University of ...

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participate in research through the program as well. Now,<br />

he’s a diagnostic imaging resident at North Carolina State<br />

<strong>University</strong>, something he attributes to his researching<br />

opportunities at the UGA CVM.<br />

Savage teamed up with research mentor Scott<br />

Schatzberg, DVM, PhD, a former associate pr<strong>of</strong>essor <strong>of</strong><br />

neurology, for some extra research experience during his<br />

fourth year at the<br />

UGA CVM. Along<br />

the way, Schatzberg<br />

recommended that<br />

Savage and another<br />

student, Dan Regan<br />

(DVM ’11), submit<br />

a joint proposal for<br />

some research they’d<br />

been conducting.<br />

Their project looked<br />

at canine degenerate<br />

myelopathy, a disease<br />

similar to amyotrophic<br />

lateral sclerosis (ALS;<br />

<strong>of</strong>ten known in the<br />

United States as Lou<br />

Gehrig’s disease)<br />

in humans. They<br />

focused on creating<br />

a molecular test that<br />

could be applied<br />

toward dogs with the<br />

disease to see if any<br />

underlying infectious<br />

agents existed, and if<br />

so, if there was any<br />

correlation between<br />

the infectious agents Erica Noland shows <strong>of</strong>f her work in the lab.<br />

in dogs with the disease<br />

and in dogs without it.<br />

“What we were really looking to do was see if there was<br />

any infection going on in these patients that we could<br />

treat,” he said.<br />

Having mentors along the way has helped Noland, too.<br />

Noland would like to thank Claudia Baumann, PhD, a<br />

research associate in the De La Fuente lab, for teaching<br />

her the necessary skills to function independently in the<br />

lab, as well as for all her guidance and help with data<br />

interpretation. Noland also would like to thank her <strong>of</strong>ficial<br />

mentor, De La Fuente, for his encouragement. In fact, it<br />

was De La Fuente who suggested Noland apply for the<br />

Morris Animal Foundation scholarship.<br />

“It’s a very prestigious award and it’s also a unique<br />

opportunity for veterinary students to get supported to do<br />

basic research,” he noted.<br />

Doing research during the summer means that these<br />

projects require a fast pace, which makes the work both<br />

fun and challenging, he said. Noland hit the ground<br />

running with several techniques, and ended up with a<br />

set <strong>of</strong> data that is now being polished up and prepped for<br />

future publishable work.<br />

“It’s rewarding to have a set <strong>of</strong> data at the end <strong>of</strong> the<br />

project period that’s in good<br />

shape for an abstract,” he said.<br />

“Eventually, what we intend<br />

to do is publish a full research<br />

paper.”<br />

The work is important for<br />

many reasons, but namely<br />

because in veterinary<br />

oncology there’s a real need to<br />

understand very basic biological<br />

mechanisms, knowledge that will<br />

provide value in basic research<br />

in other species and potentially<br />

be directly applicable to human<br />

oncology.<br />

For Noland, the opportunity to<br />

work with a wonderful research<br />

mentor and venture into the<br />

field <strong>of</strong> veterinary research for<br />

the first time has been not only<br />

exciting and fun, but has also<br />

opened up the possibility <strong>of</strong><br />

research as a potential career<br />

option in the future.<br />

Currently Noland is tying<br />

up loose ends with the project,<br />

making sure that the markers are<br />

reproducible in the cell lines, and<br />

Photo by Sue Myers Smith<br />

honing in on a new technique<br />

to quantify protein expression at<br />

the single-cell level.<br />

Eventually, a bigger goal <strong>of</strong> the project will be turning it<br />

into a global epigenetic analysis, she said.<br />

The preliminary results <strong>of</strong> her work have already been<br />

presented at the Georgia Veterinary Scholars Program<br />

Research Day in July 2011, the Merial/NIH National<br />

Veterinary Scholars Symposium in Orlando, Fla., in<br />

August 2011, and the Science <strong>of</strong> Veterinary Medicine<br />

Symposium at UGA in October 2011. All were great<br />

opportunities to network, show others what the team has<br />

been doing in the lab, and to see what others are working<br />

on in the field, Noland said.<br />

After her time at the UGA CVM, Noland says the<br />

window <strong>of</strong> opportunity is wide open for what the future<br />

may hold. She’s interested in a career in laboratory animal<br />

medicine and also has a strong interest in pathology.<br />

<strong>Aesculapian</strong> <strong>Fall</strong> <strong>2012</strong>/<strong>Winter</strong> <strong>2013</strong> 30

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