Fall 2012/Winter 2013 Aesculapian Magazine - University of ...
Fall 2012/Winter 2013 Aesculapian Magazine - University of ...
Fall 2012/Winter 2013 Aesculapian Magazine - University of ...
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participate in research through the program as well. Now,<br />
he’s a diagnostic imaging resident at North Carolina State<br />
<strong>University</strong>, something he attributes to his researching<br />
opportunities at the UGA CVM.<br />
Savage teamed up with research mentor Scott<br />
Schatzberg, DVM, PhD, a former associate pr<strong>of</strong>essor <strong>of</strong><br />
neurology, for some extra research experience during his<br />
fourth year at the<br />
UGA CVM. Along<br />
the way, Schatzberg<br />
recommended that<br />
Savage and another<br />
student, Dan Regan<br />
(DVM ’11), submit<br />
a joint proposal for<br />
some research they’d<br />
been conducting.<br />
Their project looked<br />
at canine degenerate<br />
myelopathy, a disease<br />
similar to amyotrophic<br />
lateral sclerosis (ALS;<br />
<strong>of</strong>ten known in the<br />
United States as Lou<br />
Gehrig’s disease)<br />
in humans. They<br />
focused on creating<br />
a molecular test that<br />
could be applied<br />
toward dogs with the<br />
disease to see if any<br />
underlying infectious<br />
agents existed, and if<br />
so, if there was any<br />
correlation between<br />
the infectious agents Erica Noland shows <strong>of</strong>f her work in the lab.<br />
in dogs with the disease<br />
and in dogs without it.<br />
“What we were really looking to do was see if there was<br />
any infection going on in these patients that we could<br />
treat,” he said.<br />
Having mentors along the way has helped Noland, too.<br />
Noland would like to thank Claudia Baumann, PhD, a<br />
research associate in the De La Fuente lab, for teaching<br />
her the necessary skills to function independently in the<br />
lab, as well as for all her guidance and help with data<br />
interpretation. Noland also would like to thank her <strong>of</strong>ficial<br />
mentor, De La Fuente, for his encouragement. In fact, it<br />
was De La Fuente who suggested Noland apply for the<br />
Morris Animal Foundation scholarship.<br />
“It’s a very prestigious award and it’s also a unique<br />
opportunity for veterinary students to get supported to do<br />
basic research,” he noted.<br />
Doing research during the summer means that these<br />
projects require a fast pace, which makes the work both<br />
fun and challenging, he said. Noland hit the ground<br />
running with several techniques, and ended up with a<br />
set <strong>of</strong> data that is now being polished up and prepped for<br />
future publishable work.<br />
“It’s rewarding to have a set <strong>of</strong> data at the end <strong>of</strong> the<br />
project period that’s in good<br />
shape for an abstract,” he said.<br />
“Eventually, what we intend<br />
to do is publish a full research<br />
paper.”<br />
The work is important for<br />
many reasons, but namely<br />
because in veterinary<br />
oncology there’s a real need to<br />
understand very basic biological<br />
mechanisms, knowledge that will<br />
provide value in basic research<br />
in other species and potentially<br />
be directly applicable to human<br />
oncology.<br />
For Noland, the opportunity to<br />
work with a wonderful research<br />
mentor and venture into the<br />
field <strong>of</strong> veterinary research for<br />
the first time has been not only<br />
exciting and fun, but has also<br />
opened up the possibility <strong>of</strong><br />
research as a potential career<br />
option in the future.<br />
Currently Noland is tying<br />
up loose ends with the project,<br />
making sure that the markers are<br />
reproducible in the cell lines, and<br />
Photo by Sue Myers Smith<br />
honing in on a new technique<br />
to quantify protein expression at<br />
the single-cell level.<br />
Eventually, a bigger goal <strong>of</strong> the project will be turning it<br />
into a global epigenetic analysis, she said.<br />
The preliminary results <strong>of</strong> her work have already been<br />
presented at the Georgia Veterinary Scholars Program<br />
Research Day in July 2011, the Merial/NIH National<br />
Veterinary Scholars Symposium in Orlando, Fla., in<br />
August 2011, and the Science <strong>of</strong> Veterinary Medicine<br />
Symposium at UGA in October 2011. All were great<br />
opportunities to network, show others what the team has<br />
been doing in the lab, and to see what others are working<br />
on in the field, Noland said.<br />
After her time at the UGA CVM, Noland says the<br />
window <strong>of</strong> opportunity is wide open for what the future<br />
may hold. She’s interested in a career in laboratory animal<br />
medicine and also has a strong interest in pathology.<br />
<strong>Aesculapian</strong> <strong>Fall</strong> <strong>2012</strong>/<strong>Winter</strong> <strong>2013</strong> 30