Substance Abuse and Nurses - the New Mexico Board of Nursing
Substance Abuse and Nurses - the New Mexico Board of Nursing
Substance Abuse and Nurses - the New Mexico Board of Nursing
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Chronic<br />
• Neurobiology <strong>of</strong> addiction<br />
• Use for pleasurable effect (reward) or positive<br />
reinforcement<br />
• Continued seeking <strong>of</strong> pleasure/reward<br />
• Sensitization or adaptation to reward (tolerance)<br />
• Use to avoid adverse effects (withdrawal) or negative<br />
reinforcement<br />
• Rewarded behavior is reinforcing behavior (operant<br />
conditioning)<br />
• Changes in brain chemistry can be permanent<br />
• Helps explain inability to reduce/control use <strong>and</strong> relapse<br />
after abstinence (Koob & Le Moal, 2008)