Rheumatoid Arthritis
Rheumatoid Arthritis
Rheumatoid Arthritis
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<strong>Rheumatoid</strong> <strong>Arthritis</strong>: Epidemiology<br />
• Systemic inflammatory arthritis than can also involve<br />
internal organs<br />
• Female: male ratio = 2.5:1<br />
• Prevalence ~ 1%, peak 30 – 55 years old<br />
• Genetic predisposition (HLA-DRB1)<br />
• Environmental risk factors: cigarette smoking, infection<br />
• Shortens life span, causes disability<br />
de Vries N, et al. <strong>Arthritis</strong> Rheum 2002 Apr;46(4):921-8. Pincus T, et al. J Rheumatol. 1989<br />
Klareskog L , et al. <strong>Arthritis</strong> Rheum. 2006;54:38-46. Pincus T, et al. J Rheumatol. 1987.
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