RAY OLIVER BAHADO-SINGH, MD, MBA - PUBLICATIONS 1 ...

RAY OLIVER BAHADO-SINGH, M.D., M.B.A. - PUBLICATIONS
1. Briggs GG, Moore BR, Bahado-Singh R, Lange S, Bogh P, Garite TJ. Cost-effectiveness
of cefonicid sodium versus cefoxitin sodium for prevention of postoperative infections
after nonelective cesarean section. Clin Pharm. 1987;6:718-21.
2. Bahado-Singh R, Luo JS, Reece EA, Nickless N, Belanger K, Hobbins JC. Correlation of
fetal breathing movement to outcome in diabetic pregnancies. J Matern Fetal Invest.
1992;2:33-36.
3. Bahado-Singh R, Schmitt R, Hobbins JC. New technique for genetic amniocentesis in
twins. Obstet Gynecol. 1992;79:304-7.
4. Bahado-Singh RO, Wyse L, Dorr MA, Copel JA, O’Connor T, Hobbins JC. Fetuses with
Down syndrome have disproportionately shortened frontal lobe dimensions on
ultrasonographic examination. Am J Obstet Gynecol. 1992;167:1009-14.
5. Bahado-Singh R, Morotti R, Copel JA, Mahoney MJ. Hyperechoic fetal bowel: The
perinatal consequences. Prenat Diagn. 1994;14:981-87.
6. Bahado-Singh RO, Kliman H, Feng TY, Hobbins J, Copel JA, Mahoney MJ. Firsttrimester
endocervical irrigation: Feasibility of obtaining trophoblast cells for prenatal
diagnosis. Obstet Gynecol. 1995;85:461-64.
7. Pirhonen JP, Grenman SA, Bredbacka AB, Bahado-Singh RO, Salmi TA. Effects of
external radiotherapy on uterine blood flow in patients with advanced cervical carcinoma
assessed by color Doppler ultrasonography. Cancer. 1995;76:67-71.
8. Bahado-Singh RO, Goldstein I, Uerpairojkit B, Copel JA, Mahoney MJ, Baumgarten A.
Normal nuchal thickness in the midtrimester indicates reduced risk of Down syndrome in
pregnancies with abnormal triple-screen results. Am J Obstet Gynecol. 1995;173:1106-
10.
9. Bahado-Singh RO, Tan A, Deren O, Hunter D, Copel J, Mahoney MJ. Risk of Down
syndrome and any clinically significant chromosome defect in pregnancies with
abnormal triple-screen and normal targeted ultrasonographic results. Am J Obstet
Gynecol. 1996;175:824-9.
10. Bahado-Singh RO, Deren O, Tan A, D’Ancona RL, Hunter D, Copel JA, Mahoney MJ.
Ultrasonographically adjusted midtrimester risk of trisomy 21 and significant
chromosomal defects in advanced maternal age. Am J Obstet Gynecol. 1996;175:1563-
8.
11. Bahado-Singh RO, Deren O, Tan A, D'Ancona RL, Hunter D, Copel JA, Mahoney MJ.
Ultrasonographically adjusted midtrimester risk of trisomy 21 and significant
chromosomal defects in advanced maternal age. Int J Gynecol Obstet. 1997;57:110-11.
12. Bahado-Singh RO, Lynch L, Deren O, Morroti R, Copel JA, Mahoney MJ, Williams III J.
First-trimester growth restriction and fetal aneuploidy: The effect of type of aneuploidy
and gestational age. Am J Obstet Gynecol. 1997;176:976-80.

13. Isozaki T, Palomaki G, Bahado-Singh RO, Cole LA. Screening for Down syndrome
pregnancy using ß-core fragment: Prospective study. Prenat Diagn. 1997; 17:407-13.
14. Cole LA, Jacobs M, Isozaki T, Palomaki GE, Bahado-Singh RO, Mahoney MJ.
Screening for Down syndrome using urine hCG free ß-subunit in the second trimester of
pregnancy. Prenat Diagn. 1997;17:1107-11.
15. Cole LA, Acuna E, Isozaki T, Palomaki GE, Bahado-Singh RO, Mahoney MJ. Combining
ß-core fragment and total oestriol measurements to test for Down syndrome
pregnancies. Prenat Diagn. 1997;17:1125-33.
16. Cole LA, Cermik D, Bahado-Singh R. Oligosaccharide variants of hCG-related
molecules: Potential screening markers for Down syndrome. Prenat Diagn. 1997;
17:1188-90.
17. Deren O, Mahoney MJ, Copel JA, Bahado-Singh RO. Subtle ultrasonographic
anomalies: Do they improve Down syndrome detection rate Am J Obstet Gynecol.
1997;178:441-45.
18. Bahado-Singh RO, Dashe J, Deren O, Daftary G, Copel JA, Ehrenkranz RA. Prenatal
prediction of neonatal outcome in the extremely low-birth-weight infant. Am J Obstet
Gynecol. 1998;178:462-8.
19. Bahado-Singh RO, Oz U, Deren O, Acuna E, Cermik D, Mahoney MJ, Cole L. A new
screening protocol combining urine ß-core fragment and ultrasonography for Down
syndrome detection. Am J Obstet Gynecol. 1998;178:779-82.
20. Bahado-Singh RO, Oz U, Kovanci E, Cermik D, Flores D, Copel J, Mahoney M, Cole L.
New triple screen test for Down syndrome: Combined urine analytes and serum AFP. J
Matern Fetal Med. 1998;7:111-14.
21. Bahado-Singh R, Deren O, Oz U, Tan A, Hunter D, Copel J, Mahoney MJ. An alternative
for women initially declining genetic amniocentesis: Individual Down syndrome odds on
the basis of maternal age and multiple ultrasonographic markers. Am J Obstet Gynecol.
1998;179:514-19.
22. Bahado-Singh RO, Oz U, Isozaki T, Seli E, Kovanci E, Hsu CD, Cole L. Midtrimester
urine human chorionic gonadotropin ß-subunit core fragment levels and the subsequent
development of preeclampsia. Am J Obstet Gynecol. 1998;179:738-41.
23. Cole LA, Omrani A, Cermik D, Bahado-Singh RO, Mahoney MJ. Hyperglycosylated
hCG, a potential alternative to hCG in Down syndrome screening. Prenat Diagn. 1998;
18:926-33.
24. Bahado-Singh R, Oz U, Mari G, Jones D, Paidas M, Onderoglu L. Fetal splenic size in
anemia due to Rh-alloimmunization. Obstet Gynecol. 1998;92:828-32.
25. Bahado-Singh RO, Oz AU, Kovanci E, Deren O, Copel J, Baumgarten A, Mahoney J.
New Down syndrome screening algorithm: Ultrasonographic biometry and multiple
serum markers combined with maternal ages. Am J Obstet Gynecol. 1998;179:1627-31.

26. Hsu CD, Meaddough E, Aversa K, Hoing SF, Bahado-Singh R, Copel JA. Dual roles of
amniotic fluid nitric oxide and prostaglandin E 2 in preterm labor with intra-amniotic
infection. Am J Perinatol. 1998;15:683-87.
27. Bahado-Singh R, Oz U, Deren O, Pirhonen J, Kovanci E, Copel J, Onderoglu L. A new
splenic artery Doppler velocimetric index for the prediction of severe fetal anemia
associated with Rh alloimmunization. Am J Obstet Gynecol. 1999;180:49-54.
28. Bahado-Singh R, Oz U, Kovanci E, Cermik D, Copel J, Mahoney MJ, Cole L. A highsensitivity
alternative to “routine” genetic amniocentesis: Multiple urinary analytes,
nuchal thickness, and age. Am J Obstet Gynecol. 1999;180:169-73.
29. Bahado-Singh RO, Oz AU, Flores D, Cermik D, Acuna E, Mahoney MJ, Cole L. Nuchal
thickness, urine -core fragment level, and maternal age for Down syndrome screening.
Am J Obstet Gynecol. 1999;180:491-95.
30. Bahado-Singh RO, Kovanci E, Jeffres A, Oz U, Deren O, Copel J, Mari G. The Doppler
cerebroplacental ratio and perinatal outcome in intrauterine growth restriction. Am J
Obstet Gynecol. 1999;180:750-56.
31. Bahado-Singh RO, Oz AU, Kovanci E, Deren O, Feather M, Hsu CD, Copel JA,
Mahoney MJ. Gestational age standardized nuchal thickness values for estimating midtrimester
Down’s syndrome risk. J Matern Fetal Med. 1999;8:37-43.
32. Cole LA, Rinne KM, Mahajan SM, Oz UA, Shahabi S, Mahoney MJ, Bahado-Singh RO.
Urinary screening tests for fetal Down syndrome: I. Fresh ß-core fragment. Prenat
Diagn. 1999;19:340-50.
33. Cole LA, Shahabi S, Oz UA, Rinne KM, Omrani A, Bahado-Singh RO, Mahoney MJ.
Urinary screening tests for fetal Down syndrome: II. Hyperglycosylated hCG. Prenat
Diagn. 1999;19:351-59.
34. Shahabi S, Oz UA, Bahado-Singh RO, Mahoney MJ, Omrani A, Baumgarten A, Cole LA.
Serum hyperglycosylated hCG: A potential screening test for Down syndrome. Prenat
Diagn. 1999;19:488-89.
35. Copel JA, Bahado-Singh RO. Prenatal screening for Down’s syndrome – A search for the
family’s values. N Engl J Med. 1999;341:521-22.
36. Hsu CD, Aversa KR, Lu LC, Meaddough E, Jones D, Bahado-Singh RO, Copel JA, Lee
IS. Nitric oxide: A clinically important amniotic fluid marker to distinguish between intraamniotic
mycoplasma and non-mycoplasma infections. Am J Perinatol. 1999;16:161-66.
37. Bahado-Singh R, Oz U, Rinne K, Hunter D, Cole L, Mahoney MJ, Baumgarten A.
Elevated maternal urine level of -core fragment of human chorionic gonadotropin versus
serum triple test in the second-trimester detection of Down syndrome. Am J Obstet
Gynecol. 1999;181:929-33.

38. Cole LA, Shahabi S, Oz UA, Bahado-Singh RO, Mahoney MJ. Hyperglycosylated human
chorionic gonadotropin (invasive trophoblast antigen) immunoassay: A new basis for
gestational Down syndrome screening. Clin Chem 1999;45:2109-19.
39. Prapas N, Liang R, Parkash V, Copel J, Bahado-Singh R, Mari G. Color Doppler imaging
of placental masses: Differential diagnosis and fetal outcome. J Ultrasound Med
1999;18:831-5.
40. Mari G, Deter RL, Carpenter RL, Rahman F, Zimmerman R, Moise Jr. KJ, Dorman KF,
Ludomirsky A, Gonzalez R, Gomez R, Oz U, Detti L, Copel JA, Bahado-Singh R, Berry S,
Martinez-Poyer J, Blackwell SC, for the Collaborative Group for Doppler Assessment of
the Blood Velocity in Anemic Fetuses. Noninvasive diagnosis by Doppler ultrasonography
of fetal anemia due to maternal red-cell alloimmunization. N Engl J Med. 2000;342:9-14.
41. Bahado-Singh R, Oz U, Deren O, Kovanchi E, Hsu CD, Copel J, Mari G. Splenic artery
Doppler peak systolic velocity predicts severe fetal anemia in rhesus disease. Am J
Obstet Gynecol. 2000;182:1222-26.
42. Bahado-Singh R, Oz U, Flores D, Hsu C, Mari G, Cole L. Maternal urine -core hCG
fragment level and small for gestational age neonates. Obstet Gynecol. 2000;95:662-66.
43. Hsu CD, Hong SF, Harirah H, Bahado-Singh R, Lu LC. Amniotic fluid soluble fas levels
in intra-amniotic infection. Obstet Gynecol. 2000;95:667-70.
44. Bahado-Singh R, Oz U, Shahabi S, Omrani A, Mahoney M, Cole L. Urine
hyperglycosylated hCG plus ultrasound biometry for detection of Down syndrome in the
second trimester in a high-risk population. Obstet Gynecol. 2000;95:889-94.
45. Bahado-Singh RO, Oz AU, Gomez K, Hunter D, Copel J, Baumgarten A, Mahoney MJ.
Combined ultrasound biometry, serum markers and age for Down syndrome risk
estimation. Ultrasound Obstet Gynecol. 2000;15:199-204.
46. Bahado-Singh RO, Oz UA, Hsu CD, Kovanci E, Deren O, Onderoglu L, Mari G. Middle
cerebral artery Doppler velocimetric deceleration angle as a predictor of fetal anemia in
Rh-alloimmunized fetuses without hydrops. Am J Obstet Gynecol. 2000;183:746-51.
47. Bahado-Singh RO, Oz U, Shahabi S, Mahoney MJ, Baumgarten A, Omrani A, Cole LA.
Comparison of urinary hyperglycosylated human chorionic gonadotropin concentration
with the serum triple screen for Down syndrome detection in high-risk pregnancies. Am J
Obstet Gynecol. 2000;183:1114-18.
48. Bahado-Singh RO, Oz U, Hsu CD, Deren O, Copel JA, Mahoney MJ. Ratio of nuchal
thickness to humerus length for Down syndrome detection. Am J Obstet Gynecol.
2001;184:1284-88.
49. Mari G, Roberts A, Detti L, Kovanci E, Stefos T, Bahado-Singh RO, Deter RL, Fisk NM.
Perinatal morbidity and mortality rates in severe twin-twin transfusion syndrome: Results
of the International Amnioreduction Registry. Am J Obstet Gynecol. 2001;185:708-15.
50. Detti L, Oz U, Guney I, Ferguson JE, Bahado-Singh RO, Mari G, for the Collaborative
Group for Doppler Assessment of the Blood Velocity in Anemic Fetuses. Doppler

ultrasound velocimetry for timing the second intrauterine transfusion in fetuses with
anemia from red cell alloimmunization. Am J Obstet Gynecol. 2001;185:1048-51.
51. Deren Ö, Karaer C, Önderoğlu L, Yigit N, Durukan T, Bahado-Singh RO. The effect of
steroids on the biophysical profile and Doppler indices of umbilical and middle cerebral
arteries in healthy preterm fetuses. Eur J Obstet Gynecol Reprod Biol. 2001; 99:72-6.
52. Bahado-Singh R, Shahabi S, Karaca M, Mahoney MJ, Cole L, Oz UA. The
comprehensive midtrimester test: High-sensitivity Down syndrome test. Am J Obstet
Gynecol. 2002;186:803-8.
53. Bahado-Singh RO, Oz AU, Kingston JM, Shahabi S, Hsu CD, Cole L. The role of
hyperglycosylated hCG in trophoblast invasion and the prediction of subsequent preeclampsia.
Prenat Diagn. 2002;22:478-81.
54. Oz AU, Holub B, Mendilcioglu I, Mari G, Bahado-Singh RO. Renal artery Doppler
investigation of the etiology of oligohydramnios in postterm pregnancy. Obstet Gynecol.
2002;100:715-18.
55. Oz U, Kovanci E, Jeffress A, Mendilicioglu I, Mari G, Bahado-Singh RO. Splenic artery
Doppler in the prediction of the small-for-gestational age infant. Ultrasound Obstet
Gynecol. 2002;20:346-50.
56. Bahado-Singh RO, Mendilcioglu I, Rowther M, Choi SJ, Oz U, Yousefi NF, Mahoney MJ.
Early genetic sonogram for Down syndrome detection. Am J Obstet Gynecol. 2002;
187:1235-38.
57. Bahado-Singh RO, Rowther M, Bailey J, Mendilcioglu I, Choi SJ, Oz U, Copel J.
Midtrimester nuchal thickness and the prediction of postnatal congenital heart defect. Am
J Obstet Gynecol. 2002;187:1250-53.
58. Cosmi E, Mari G, Delle Chiaie L, Detti L, Akiyama M, Murphy J, Stefos T, Ferguson II JE,
Hunter D, Hsu CD, Abuhamad A, Bahado-Singh R. Noninvasive diagnosis by Doppler
ultrasonography of fetal anemia resulting from parvovirus infection. Am J Obstet Gynecol.
2002;187:1290-93.
59. Hobbins JC, Lezotte DC, Persutte WH, DeVore GR, Benacerraf BR, Nyberg DA,
Vintzileos AM, Platt LD, Carlson DE, Bahado-Singh RO, Abuhamad AZ. An 8-center
study to evaluate the utility of mid-term genetic sonograms among high-risk pregnancies.
J Ultrasound Med. 2003;22:33-38.
60. Bahado-Singh RO, Choi SJ, Oz U, Mendilcioglu I, Rowther M, Persutte W. Early secondtrimester
individualized estimation of trisomy 18 risk by ultrasound. Obstet Gynecol.
2003;101:463-68.
61. Platt LD, Greene N, Johnson A, Zachary J, Thom E, Krantz D, Simpson JL, Silver RK,
Snijders RJ, Goetzl L, Pergament E, Filkins K, Mahoney MJ, Hogge WA, Wilson RD,
Mohide P, Hershey D, MacGregor S, Bahado-Singh R, Jackson LG, Wapner R, First
Trimester Maternal Serum Biochemistry and Fetal Nuchal Translucency Screening (BUN)

Study Group. Sequential pathways of testing after first-trimester screening for trisomy 21.
Obstet Gynecol. 2004 Oct;104(4):661-6.
62. Cheng CC, Bahado-Singh RO, Chen SC, Tsai MS. Pregnancy outcomes with increased
nuchal translucency after routine Down syndrome screening. Int J Gynaecol Obstet.
2004;84:5-9.
63. Detti L, Mari G, Cheng CC, Bahado-Singh RO. Fetal Doppler velocimetry.
Obstet Gynecol Clin North Am. 2004 Mar;31(1):201-14.
64. Bahado-Singh, RO, Cheng CS. First trimester prenatal diagnosis. Curr Opin Obstet
Gynecol. 2004 Apr;16(2):177-81.
65. Doubilet PM, Copel JA, Benson CB, Bahado-Singh RO, Platt LD. Choroid plexus cyst
and echogenic intracardiac focus in women at low risk for chromosomal anomalies: the
obligation to inform the mother. J Ultrasound Med. 2004 Jul;23(7):883-5.
66. Preciado DA, Rutter MJ, Greenberg JM, Bahado-Singh RO, Lambers D, Willging JP.
Intrapartum management of severe fetal airway obstruction. J Otolaryngol. 2004
Oct;33(5):283-8.
67. Bahado-Singh RO, Choi SJ, Cheng CC. First- and midtrimester Down syndrome
screening and detection. Clin Perinatol. 2004 Dec;31(4):677-94.
68. Bahado-Singh, RO, Sutton-Riley J. Biochemical screening for congenital defects. Obstet
Gynecol Clin North Am. 2004 Dec;31(4):857-72.
69. Bahahdo-Singh RO, Wapner R, Thom E, Zachary J, Platt L, Mahoney MJ, Johnson A,
Silver RK, Pergament E, Filkins K, Hogge WA, Wilson RD, Jackson LG; First Trimester
Maternal Serum Biochemistry and Fetal Nuchal Translucency Screening Study Group.
Elevated first-trimester nuchal translucency increases the risk of congenital heart defects
Am J Obstet Gynecol. 2005 May; 192(5):1357-61.
70. Bahado-Singh RO, Oz UA, Mendilcioglu I, Mahoney MJ. The mid-trimester genetic
sonogram. Semin Perinatol. 2005 Aug; 29(4):209-14.
71. Nien JK, Yoon BH, Espinoza J, Kusanovic JP, Erez O, Soto E, Richani K, Gomez R,
Hassan S, Mazor M, Edwin S, Bahado-Singh R, Romero R. A rapid MMP-8
bedside test for the detection of intra-amniotic inflammation identifies patients at
risk for imminent preterm delivery. Am J Obstet Gynecol. 2006 Oct;195(4):1025-
30.
72. Bahado-Singh R, Driscoll D. ACOG Practice Bulletin. Clinical Management
Guidelines for Obstetrics-Gynecologists. Screening for Fetal Chromosomal
Abnormalities. Number 77, January 2007.
73. Segata M, Chaoui R, Khalek N, Bahado-Singh R, Paidas MJ, Mari G. Fetal
thrombocytopenia secondary to parvovirus infection. Am J Obstet Gynecol 2007
Jan;196(1):1-4.

74. Bahado-Singh R, Raymond M. The 20-week scan: Beyond biometry and
anatomy. Clin Obstet Gynecol 2007; 50(2): 478-486.
75. Crombleholme T, Bahado-Singh R, and TTT Study Team. A prospective
randomized multicenter trial of amnioreduction versus selective fetoscopic laser
photocoagulation for the treatment of severe twin-twin transfusion syndrome. Am
J Obstet Gynecol 2007 Oct;197(4):396.e1-9.
76. Bahado-Singh RO, Khalek N, Short A. Ultrasound technology for the accurate
detection of fetal anomalies, US Obstetrics and Gynecology 2007.
77. Imudia AN, Awonuga AO, Dbouk T, Kumar S, Cordoba M, Diamond MP,
Bahado-Singh RO. Incidence, trends, risk factors, indications for, and
complications associated with cesarean hysterectomy: A 17-year experience
from a single Institution. Arch Gynecol Obstet 2009 (in press)
78. Imudia AN, Awonuga AO, Dbouk T, Kumar S, Cordoba M, Diamond MP,
Bahado-Singh RO. Racial disparity in the clinical determinants and outcomes of
cesarean hysterectomy. J Natl Med Assoc 2009; 101:565-568.
79. Bahado-Singh RO, Barbu D, Mert I. Congenital heart defect and the effect on
fetal brain growth. Am J Obstet Gynecol (in press)