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Issue 1 - San Antonio Breast Cancer Symposium

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<strong>Issue</strong> 1, December 10, 2009<br />

Brinker Awards Go to Researchers in Endocrine Therapy<br />

Susan G. Komen for the Cure® Brinker Awards for Scientific Distinction (continued)<br />

Genomics of Estrogen Receptor Signaling in <strong>Breast</strong> <strong>Cancer</strong> and Endocrine Resistance<br />

Thursday, December 10, 4:45 pm<br />

Benita katzenellenbogen, PhD<br />

University of Illinois-Urbana Champaign, Urbana, IL<br />

Benita S. Katzenellenbogen, PhD, will also receive an award for basic science research.<br />

Dr Katzenellenbogen, PhD, is the Swanlund Professor of Molecular and Integrative Physiology,<br />

Cell and Developmental Biology at the University of Illinois Urbana-Champaign. She is a world expert<br />

on nuclear hormone receptors, especially on estrogen receptors and their actions in breast cancer.<br />

Her work has elucidated fundamental aspects of structure-function relationships and mechanisms of<br />

action of the estrogen receptors, and has provided a framework for the development of anti-hormonal<br />

treatments that are used in breast cancer treatment and prevention. Dr Katzenellenbogen has trained<br />

many young investigators who have gone on to successful careers, and she has served on many important<br />

committees and review panels and as President of the Endocrine Society from 2000-2001. Her research<br />

contributions have been recognized by multiple prestigious awards and honors from professional<br />

societies and foundations.<br />

Getting the Best Out of Neoadjuvant Therapy<br />

Thursday, December 10, 5:00 pm<br />

Professor Ian Smith<br />

Royal Marsden Hospital, London, United Kingdom<br />

Professor Ian Smith is Professor of <strong>Cancer</strong> Medicine at the Institute of <strong>Cancer</strong> Research and the Royal<br />

Marsden Hospital, London, where he is also the Head of the <strong>Breast</strong> Unit. His principal research interests<br />

have been in the biology and treatment of breast cancer and lung cancer, and in new drug development. He<br />

was involved in the early clinical development of several successful anti-cancer drugs, including letrozole<br />

and carboplatin. One of his main interests is in neoadjuvant and short-term preoperative treatments<br />

and in the molecular changes associated with these therapies. He is Chief Investigator of 2 international<br />

neoadjuvant endocrine therapy trials, IMPACT and IRESSA 223, and the UK Principal Investigator for<br />

several international multicenter adjuvant trials, including HERA (trastuzumab), BIG1-98 (letrozole), and<br />

ALTTO (lapatinib). He is the first chairman of the recently formed UK <strong>Breast</strong> Trials Intergroup and recent<br />

past chairman of the British <strong>Breast</strong> Group. He has also been Chairman of several national professional<br />

bodies, including the Association of the <strong>Cancer</strong> Physicians, the Royal College of Physicians Specialist Advisory Committee for<br />

Medical Oncology, and the NCRI Lung <strong>Cancer</strong> Clinical Studies Group. He is a member of numerous international cancer societies<br />

and has over 300 peer-reviewed publications.<br />

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