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Psychiatric Diagnosis and Classification - ResearchGate

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<strong>Psychiatric</strong> <strong>Diagnosis</strong> <strong>and</strong> <strong>Classification</strong>. Edited by Mario Maj, Wolfgang Gaebel, Juan Jose LoÂpez-Ibor <strong>and</strong> Norman Sartorius<br />

Copyright # 2002, John Wiley & Sons, Ltd. ISBNs: 0±471±49681±2 Hardback); 0±470±84647±X Electronic)<br />

Preface<br />

The next editions of the two main systems for the diagnosis <strong>and</strong> classification<br />

of mental disorders, the ICD <strong>and</strong> the DSM, are not expected before the<br />

year 2010. The most frequently alleged reasons for this long interval are: 1)<br />

the satisfaction with the performance of the systems as they are now, since<br />

they are achieving their goals of improving communication among clinicians<br />

<strong>and</strong> ensuring comparability of research findings; 2) the concern that<br />

frequent revisions of diagnostic systems may undermine their assimilation<br />

by clinicians, damage the credibility of our discipline, <strong>and</strong> hamper the<br />

progress of research by making the comparison between old <strong>and</strong> new<br />

data more difficult, impeding the collection of large patient samples, <strong>and</strong><br />

requiring a ceaseless update of diagnostic interviews <strong>and</strong> algorithms); 3)<br />

the presentiment that we are on the eve of major research breakthroughs,<br />

which may have a significant impact on nosology. There is a further reason,<br />

however, for the current hesitation to produce a new edition of the above<br />

diagnostic systems, which is seldom made explicit, but is probably not the<br />

least important: i.e. the gradually spreading perception that there may have<br />

been something incorrect in the assumptions put forward by the neo-Kraepelinian<br />

movement at the beginning of the 1970s, which have guided the<br />

development of the modern generation of diagnostic systems.<br />

That current diagnostic categories really correspond to discrete natural<br />

disease entities is appearing now more <strong>and</strong> more questionable. <strong>Psychiatric</strong><br />

``comorbidity'', i.e. the coexistence of two or more psychiatric diagnoses in<br />

the same individual, seems today the rule rather than the exception. Thirty<br />

years of biological research have not been able to identify a specific marker<br />

for any of the current diagnostic categories <strong>and</strong> genetic research is now<br />

providing evidence for the possible existence of vulnerability loci which are<br />

common to schizophrenia <strong>and</strong> bipolar disorder). Also the therapeutic profile<br />

of newly developed psychotropic drugs clearly crosses old <strong>and</strong> new<br />

diagnostic boundaries e.g. new generation antipsychotics appear to be as<br />

effective in schizophrenia <strong>and</strong> in bipolar disorder, <strong>and</strong> new generation<br />

antidepressants are effective in all the various disorders identified by current<br />

classification systems in the old realm of neuroses).<br />

The fact that current diagnostic categories are unlikely to correspond to<br />

discrete natural disease entities has been taken as evidence that the neo-<br />

Kraepelinian or neo-Pinelian) model was intrinsically faulty, i.e. that psychopathology<br />

does not consist of discrete disease entities. This has been

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