Pharmaceutical Additives

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<strong>Pharmaceutical</strong> <strong>Additives</strong> n n Propylene glycol n IV preps pushed rapidly n Hypotension, bradycardia, asystole n Prolonged infusions n Lactic acid production Polyethylene glycol n Toxicity concern with low MWs (< 400) n Risk of renal tubular necrosis 0
Gasping Syndrome n n n n In 1981 16 neonatal deaths occurred in a NICU All were pre-term neonates < 2500 gm Symptoms included severe AGMA, respiratory depression with gasping, and encephalopathy All neonates had received bacteriostatic NaCl or water flushes containing 0.9% benzyl alcohol 0
Page 1 and 2: Pharmaceutical Additives G. Patrick
Page 3: Pharmaceutical Additives n n n n n
Page 7 and 8: DEG and Sulfanilamide n September-O
Page 9 and 10: Eosinophilia Myalgia Syndrome n n n
Page 11 and 12: Pharmaceutical Additives n Thorotra
Page 13 and 14: Question Which of the following pha
Page 15 and 16: Vitamin A n n n n Binds retinal bin
Page 17 and 18: Vitamin E n n n n Antioxidant Defic
Page 19 and 20: Vitamin B1 (Thiamine) n n n Coenzym
Page 21 and 22: Vitamin B3 (Niacin or Nicotinic aci
Page 23 and 24: Vitamin B12 (Cyanocobalamin) n Coen
Page 25 and 26: Question Which of the following cli
Page 27 and 28: Food Additives 0
Page 29 and 30: Food Additives n n n Sulfites (red
Page 31 and 32: Question A young boy presents to th
Page 33: Questions Good Luck!! 0

Pharmaceutical Additives

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