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Schedule of Events<br />

Thursday, February 10th, 2011<br />

7:00pm Happy Hour Off Campus<br />

Sponsored by Postdoctoral Association Social Committee<br />

Friday, February 11th, 2011<br />

2:00-3:00pm Transferable Skills Workshop (By RSVP only) NB11.120<br />

Sponsored by the PDA Career Development Committee<br />

5:00pm Posters on display 3rd Floor Commons (NG3)<br />

Postdoctoral scholars display their posters.<br />

Monday, February 14th, 2011<br />

2:00-3:00pm CV/Resume Workshop (All welcome) EEF Auditorium (NB2)<br />

Sponsored by the PDA Career Development Committee<br />

Wednesday, February 16th, 2011<br />

1:30-3:30pm Poster Session 3rd Floor Commons (NG3)<br />

Postdoctoral scholars will be present at their posters to discuss their research. Refreshments will<br />

be served.<br />

4:00-5:00pm University Lecture Series EEF Auditorium (NB2)<br />

Speaker: Ruslan Medzhitov, Ph.D. Yale University School of Medicine, New Haven, CT<br />

Sponsored by the Postdoctoral Association at <strong>UT</strong> <strong>Southwestern</strong><br />

5:15-7:00pm Reception and Awards Ceremony 14th floor (ND14)<br />

Join us immediately following the ULS for a reception and presentation of awards, including:<br />

- Award for Excellence in Postdoctoral Research ($2000)<br />

- Best posters<br />

- Award for Excellence in Postdoctoral Mentoring<br />

- Distinguished Service Award<br />

Food & cash bar provided (one complimentary drink ticket for participants & judges).<br />

2010 Postdoctoral Research Symposium Poster Session


UNIVERSITY LECTURE<br />

Host Defense: Mechanisms and Pathways<br />

Ruslan Medzhitov, Ph.D.<br />

Professor, Howards Hughes Investigator, National Academy of Sciences<br />

Yale University School of Medicine, New Haven, CT<br />

Professor Medzhitov is the David W. Wallace Professor of Immunobiology at Yale and a Howard Hughes<br />

Medical Institute investigator. Dr. Medzhitov is a pioneering researcher in the field of the innate immune<br />

system and along with Dr. Charles Janeway made the groundbreaking discovery that Toll-like receptors,<br />

a component of the innate system, provide the adaptive system with the necessary information to create<br />

custom-made B and T cells that target specific bacterial or viral invaders. Dr. Medzhitov’s lab is continuing<br />

to investigate the role of Toll-like receptors in how the innate immune system controls the adaptive system<br />

– particularly their role in autoimmune disorders, inflammation and allergy – with the goal of developing<br />

new strategies for vaccine design. In recognition of his prolific contributions to the field of immunological<br />

research, in 2010 Dr. Medzhitov was elected to the National Academy of Sciences and was awarded the<br />

prestigious Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Science.<br />

Previous University Lecture speakers sponsored by the Postdoctoral Symposium:<br />

2010 Huda Zoghbi, M.D. Baylor College of Medicine<br />

2008 Tom Maniatis, Ph.D. Harvard University<br />

2007 Joan Massagué, Ph.D. Memorial Sloan-Kettering Cancer Center<br />

2006 Kathryn Anderson, Ph.D. Memorial Sloan-Kettering Cancer Center<br />

2005 Rama Ranganathan, M.D., Ph.D. <strong>UT</strong> <strong>Southwestern</strong> Medical Center<br />

2004 Suzanne Pfeffer, Ph.D. Stanford University


Acknowledgments<br />

The Postdoctoral Association at <strong>UT</strong> <strong>Southwestern</strong> medical center is proud to host the 8th Annual Postdoctoral<br />

Research Symposium. This symposium provides a platform for postdoctoral scholars from across the<br />

campus to present their research, and is a showcase for the outstanding work done at <strong>UT</strong> <strong>Southwestern</strong>.<br />

Over a hundred postdoctoral fellows will be presenting their work in this year’s symposium.<br />

An event of this scale is possible only due to the efforts of numerous people. The PDA received generous<br />

funding and administrative support from the former Dean, Dr. Melanie Cobb, as well as the Graduate<br />

School of Biomedical Sciences, who made this symposium possible. Our special thanks go out to Dr. Deirdre<br />

Brekken, Adjunct Assistant Professor and Michelle Greer, Administrative Associate in the Postdoctoral<br />

Affairs Office for their tireless efforts in organizing and coordinating this event. We also thank Dr. Susanne<br />

Mumby, Assistant Dean of Postdoctoral Affairs for her continued support.<br />

We would like to thank Dr. Steven McKnight, Professor and Chair of the Department of Biochemistry,<br />

who kindly agreed to be the symposium faculty chair this year. Dr. McKnight played an important role<br />

in the symposium, encouraging faculty involvement, coordinating poster judging and hosting the awards<br />

reception. We especially thank the faculty who participated in the symposium and served as judges for the<br />

posters submitted. Their support was critical towards the success of this event.<br />

As always we are grateful for the support from all our sponsors, listed in this symposium booklet, for<br />

providing funding to help make the Awards Reception a very special event.<br />

This event is unique in that it is organized and executed largely by the postdoctoral fellows themselves.<br />

This year was also special in that we have extended the symposium to include a postdoc mixer organized by<br />

the PDA Social Committee, as well as a workshop on transferable skills and CV/Resume seminar organized<br />

by the PDA Career Develeopment Committee. These efforts significantly increase the scope and breadth<br />

of the PDA symposium, and also speak of the strong collaborative efforts within the PDA community. A<br />

big thank you to these PDA committees. We hope to see more such participation next year. Finally, we<br />

would like to acknowledge our vibrant and ever-enthusiastic symposium committee members who took<br />

out time from their hectic schedules to help with the tremendous planning involved in making this event a<br />

successful one. We really appreciate all the time you put into this event.<br />

Finally, and most importantly, thank you to all the postdoctoral scholars at <strong>UT</strong>SW for their continuing<br />

commitment and dedication to science and discovery.<br />

Sincerely,<br />

Pavan Battiprolu, Ph.D. and Sunil Laxman, Ph.D.<br />

Co-Chairs, Eighth Annual Postdoctoral Research Symposium


The Annual Postdoctoral Research Symposium has become a keystone event that provides a wonderful<br />

platform for our postdoctoral community to showcase their scientific research and promotes the free<br />

exchange of scientific ideas of things yet to come. It also serves the stated mission of the Postdoctoral<br />

Association, “to develop a sense of community throughout our institution”. The Postdoctoral Association<br />

grows increasingly proud of the research accomplished by postdoctoral scholars here at <strong>UT</strong> <strong>Southwestern</strong>.<br />

Our postdoctoral community continues making milestone contributions to a wide variety of science fields.<br />

On behalf of the Postdoctoral Association I would like to thank all of the participants who have graciously<br />

agreed to share their work with the university as a whole. I would also like to thank the organizers who<br />

have volunteered their time and efforts to making the annual Postdoctoral Research Symposium a successful<br />

event.<br />

Thank you and congratulations,<br />

Jose A. Barrera, Ph.D.<br />

President, Postdoctoral Association<br />

2010 Symposium Committee<br />

Back row: Jill Larsen, Elhadji Dioum, Sunil Laxman, Steve McKnight, Wen-Huang (Lisa) Ko, Jyh-Yeuan<br />

(Eric) Lee, Pavan Battiprolu, Houda Benlhabib. Front row: Daniela Derderian, Brett Pickett, Charlene<br />

Supnet, Diana Canseco, Myriam Iglewski, Deirdre Brekken. Not pictured: Michelle Greer, Sohini<br />

Mukherjee.


AWARDS<br />

Distinguished Service Award<br />

This award honors a <strong>UT</strong> <strong>Southwestern</strong> postdoctoral fellow, faculty, or staff member who has shown<br />

extraordinary dedication to helping <strong>UT</strong> <strong>Southwestern</strong> postdoctoral scholars. The Postdoctoral Association<br />

(PDA) is proud to announce that the recipients for this year’s award are Cathy Cavins and Cory Blaiss,<br />

Ph.D.<br />

Cathy Cavins joined the Graduate School staff in November 2004. With<br />

Cathy’s assistance, both the Postdoctoral Affairs Office and the PDA at <strong>UT</strong><br />

<strong>Southwestern</strong> were established. Cathy was a dedicated advocate for the<br />

postdoctoral scholars by providing them guidance in both their training<br />

and along their career path. Her support of postdoctoral training greatly<br />

enhanced the experience of postdoctoral scholars at <strong>UT</strong> <strong>Southwestern</strong>.<br />

Since June 2009, Cathy has been serving the Postdoctoral Affairs Office<br />

as a Subject Matter Expert for the Campus Solutions PeopleSoft project,<br />

which will replace the current postdoctoral certificate registration system<br />

next year.<br />

Dr. Cory Blaiss joined the lab of Dr. Craig Powell in the Department of<br />

Cathy Cavins<br />

Neurology as a postdoctoral scholar in 2008. Shortly after coming to <strong>UT</strong><br />

<strong>Southwestern</strong>, Cory enthusiastically volunteered for many PDA committees. Her most prominent and<br />

passionate involvements include, President (2008-2009), Co-chair of the Career Development Committee<br />

(2008-2010), Treasurer (2009-2010), and postdoctoral departmental representative for the Department of<br />

Neurology. Cory also demonstrated untiring dedication and enthusiasm as a member of the Symposium,<br />

Standards, and Outreach committees. Her initiative was evident in the ideas she implemented after<br />

attending the annual National Postdoc Association (NPA) meeting in<br />

2009 as well as her pioneering contributions towards workshops on<br />

negotiations skills, peer-mentoring discussions and updating the PDA<br />

travel awards. In addition to the PDA committees, Cory served on the<br />

Student/Trainee Subcommittee of the <strong>UT</strong> <strong>Southwestern</strong> Six-Year Planning<br />

Committee (2009-2010). Cory continues to be an active member of the<br />

Advocacy Committee of the NPA. It is her remarkable leadership qualities<br />

that serve as a role model for other postdoctoral scholars.<br />

Together with faculty members, both Cathy and Cory have served on the<br />

Postdoctoral Advisory Committee. We take this opportunity to thank<br />

Cathy and Cory for their dedicated and selfless efforts to advocate for<br />

all postdoctoral scholars and for their help in bringing the PDA and<br />

Postdoctoral Symposium to where they stand today.<br />

Cory Blaiss, Ph.D.<br />

Previous winners of the Distinguished Service Award:<br />

2010 Brenda Timmons, Ph.D. Postdoctoral Fellow, Dept. of Ob/Gyn (2003-2009)<br />

2008 Sue Harjo Director of Graduate and Postdoctoral Affairs (2003-2008)


AWARDS<br />

Award for Excellence in Postdoctoral Mentoring<br />

This award recognizes and honors <strong>UT</strong> <strong>Southwestern</strong> faculty who have demonstrated excellence in their<br />

ability to advise and mentor postdoctoral scholars. The finalists for this award consistently demonstrate a<br />

strong commitment to postdoctoral mentoring by providing research guidance in a healthy and collaborative<br />

working environment. They are committed to promoting career development, whether it be fostering the<br />

transition to independence or supporting the scholar in an alternative career path.<br />

Over thirty different faculty members were nominated for the award by their current postdoctoral scholars,<br />

and we thank all the postdocs who wrote such wonderful nomination letters in support of their mentors. The<br />

finalists have been notified and the two winners of the 2011 Award will be announced at the Symposium’s<br />

Reception and Awards Ceremony. We hope that everyone will be able to attend and express their support<br />

for continuing excellence in postdoctoral mentoring at <strong>UT</strong> <strong>Southwestern</strong>.<br />

Previous winners of the Award for Excellence in Postdoctoral Mentoring:<br />

2010 David Corey, Ph.D. Dept. of Pharmacology<br />

Gang Yu, Ph.D.<br />

Dept. of Neuroscience<br />

2008 Harold “Skip” R. Garner, Jr., Ph.D. Dept. of Biochemistry


AWARDS<br />

Award for Excellence in Postdoctoral Research<br />

This top award honors the outstanding accomplishments of a postdoctoral scholar participating in the<br />

Postdoctoral Certificate Training Programs of the Graduate School of Biomedical Sciences. Nominations are<br />

sought from faculty members and postdoctoral scholars and finalists are interviewed by the Committee on<br />

Graduate School Awards. The committee chooses the awardee based on the scholar’s creativity, productivity<br />

during postdoctoral training, presentation skills and potential of an outstanding independent research<br />

path and on his or her research project’s originality, depth, and documented scientific impact. The award<br />

includes $2000 and presentation of the University Lecture the week following the Awards Reception.<br />

Susanne Mumby, Ph.D.<br />

Assistant Dean of Postdoctoral Affairs<br />

2011 Finalists for Excellence in Postdoctoral Research<br />

William Holland, Ph.D.<br />

Dept. of Internal Medicine<br />

Mentor: Philipp Scherer, Ph.D.<br />

Viviana Moresi, Ph.D.<br />

Dept. of Molecular Biology<br />

Mentor: Eric Olson, Ph.D.<br />

Carrie Partch, Ph.D.<br />

Dept. of Biochemistry<br />

Mentor: Kevin Gardner, Ph.D.<br />

Tongjin Zhao, Ph.D.<br />

Dept. of Molecular Genetics<br />

Mentor: Joseph Goldstein, M.D.<br />

Previous winners of the Award for Excellence in Postdoctoral Research:<br />

2010 Lit-Hsin Loo, Ph.D. Dept. of Pharmacology Mentor: Lani Wu, Ph.D. &<br />

Steven Altschuler, Ph.D.<br />

2008 Shusheng Wang, Ph.D. Dept. of Molecular Biology Mentor: Eric Olson, Ph.D.<br />

2007 Angelique Whitehurst, Ph.D. Dept. of Cell Biology Mentor: Michael White, Ph.D.


INDEX OF POSTERS<br />

BY CATEGORY<br />

Biochemistry<br />

1. Schaeffer R, Automated domain partition using evolutionary considerations<br />

2. Lee A, WNK3 is a component of RNA granules<br />

3. Yu S, Capturing O-GlcNAc’s interactions via photocrosslinkable sugar<br />

4. Hattne J, Independent component analysis of noisy data<br />

5. Stiffler M, The heterogeneity of mutational tolerance in a protein is dependent on the strength of<br />

selective pressure<br />

6. Sankella S, Determination of the sn-2 fatty acid composition of liver phospholipids in Agpat2 knockout<br />

mice<br />

7. Han Y, The facilitation of gamma-secretase proteolytic activity by the extracellular domain of Nicastrin<br />

is dependent on a major conformation change<br />

8. Kumar B, Rpt3, an ATPase subunit of PA700 (19S regulator), is essential for asymmetric assembly of<br />

26S proteasome<br />

9. Huang Y, Nutritional regulation of PNPLA3 in liver<br />

10. Li B, A two-hybrid assay to study protein interactions within the secretory pathway<br />

11. Correa F, Blue light sensing two-component systems: structural studies in a anti-antisigma factor<br />

response regulator<br />

12. Sun T, The PR70 subunit of PP2A regulates the levels of Cdc6 and DNA pre-replication complex<br />

formation in U2OS cells<br />

13. Jia D, Mechanism of retromer-coated endosomal tubulation and tubular scission<br />

14. Reynolds K, A mechanism for the evolution of allosteric control in proteins<br />

15. Annavarapu H, Hypoxia mediates cervical ripening by repressing MITF gene expression and<br />

activation of IL8 gene expression<br />

16. Kim J, Vacuum matrix sublimation for self-assembled monolayer desorption/ionization immunoassay<br />

17. Ramesh A, RNA-mediated gene regulation by bacterial two-component systems<br />

18. Dorwart M, MscL is a pentamer in vivo but of variable stoichiometries in vitro: implications for<br />

detergent-solubilized membrane proteins<br />

19. He X, A multi-layered autoinhibition mechanism of FARP2, a GEF involved in plexin signaling<br />

Cancer Biology<br />

20. Marin-Valencia I, Does the Warburg effect exist in vivo Analyzing glucose metabolism in FDG-PETpositive<br />

tumors using 13C-NMR spectroscopy<br />

21. Yaacoub R, Expression of cell cycle-related Molecular Markers in patients treated with radical<br />

cystectomy for sqamous cell carcinoma of the bladder<br />

22. Li L, Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of ß-<br />

lapachone for pancreatic cancer therapy<br />

23. Park J, PRMT1-mediated methylation of high-risk HPV-16 E6 oncoprotein derepresses p53-dependent<br />

gene transcription<br />

24. Tiwari A, Expression of SOX9 differs in esophageal squamous cells from GERD patients with and<br />

without Barrett’s esophagus<br />

25. Fattah K, Role of DNA-PK in homologous recombination<br />

26. Larsen J, Defining the role of ZEB1 in the molecular pathogenesis of lung cancer<br />

27. Alcantara Llaguno S, Hox genes are essential for glioma stem cell survival and tumorigenicity<br />

28. Potts M, Identification of genetic and chemical inhibitors of multiple cancer-related signaling<br />

pathways


Cancer Biology, continued<br />

29. Park J, Adipocyte-derived Type VI Collagen A3-C5 promotes mammary tumor growth and metastasis<br />

in vivo<br />

30. Rabellino A, The SUMO ligase PIAS1 promotes tumorigenesis through regulation of PML protein<br />

levels<br />

31. Schuster K, Lung cancer initiating cells in a mouse model deficient in Cdkn2ab<br />

32. Cheng T, Pyruvate carboxylase catalyzes an alternative metabolic strategy allowing tumor cells to<br />

escape glutamine dependence<br />

33. Galindo K, D-Mef2 studies in a drosophila model of rhabdomyosarcoma<br />

34. Dellinger M, Inhibition of VEGF-A activation of VEGFR2 blocks lymphangiogenesis by preventing<br />

LEC proliferation and migration<br />

35. Sun J, Ku Blocking on Exo1-mediated end resection is not resolved by Mre11<br />

Cardiology<br />

36. Iglewski M, Developing an in vitro model for studying cardiomyocyte mitophagy<br />

37. Burchfield J, Induction of cardiac myocyte phenotype in adipose-derived stem cells by a novel<br />

cardiogenic small molecule<br />

38. Nemchenko A, AMPK suppresses autophagy in redox-stressed cardiomyocytes<br />

39. Rotter D, What are the relevant targets of circadian calcineurin/NFAT activity in the heart<br />

40. Battiprolu P, Persistent activation of FoxO transcription factors contributes to insulin resistance and<br />

diabetic cardiomyopathy<br />

41. Zhu M, The role of FoxO4 in the remodeling process after myocardial infarction<br />

42. Canseco D, Cytoglobin: a stress-responsive hemoprotein regulating cardiomyocyte homeostasis and<br />

survival<br />

43. Zhang Q, The histone trimethyl demethylase, JMJD2A, promotes pressure overload-induced cardiac<br />

hypertrophy<br />

44. Lee W, PDZK1 in vascular smooth muscle provides protection from neointima formation<br />

Cell Biology<br />

45. Saddar S, Scavenger receptor Class B Type I (SR-BI) is a plasma membrane cholesterol sensor<br />

46. Shah P, Abrogation by N-acetyl cysteine of cytotoxic and metabolic effects of silver cations on a model<br />

of respiratory epithelium<br />

47. Yarbrough M, miRNA regulation of viral infection and mRNA export pathways<br />

48. Lai H, Brd4 inhibits G9a-mediated methylation of Histone H3 and p53<br />

49. Morales J, Linking transcription termination and DNA damage response through KUB5 function<br />

50. Song K, Cardiac repair by reprogramming fibroblasts to cardiomyocytes by defined factors<br />

51. Herrera-Herrera M, Role of DDR2 in adhesion, contraction and migration of fibroblasts<br />

52. Han S, A human SPO7 candidate that forms a phosphatase complex with CTPNEP1 (formerly<br />

Dullard) to activate lipin<br />

53. Wu Q, Identification of point mutations of estrogen receptor a (ERa) that provide genetic segregation<br />

of nuclear versus non-nuclear receptor function<br />

54. Tomimatsu N, DNA resection by Exo1 dictates critical DNA repair and damage signaling decisions in<br />

response to DNA double-strand breaks<br />

55. Ning J, CrGex1 is a gamete-specific protein required for zygote germination<br />

Chemistry<br />

56. Hu Y, Biologically active natural products from marine microorganisms


Chemistry, continued<br />

57. Soheili A, Synthesis of unnatural amino acids from glycine<br />

Computational and Systems Biology<br />

58. Cheng H, Detecting remote protein homologs using structures and sequences<br />

59. Artyukhin A, Quorum sensing in C. elegans starvation<br />

60. Jilkine A, A density-dependent switch for controlling the onset of stochastic cell polarization and<br />

formation of signalling clusters<br />

61. Poelwijk F, The evolutionary design of proteins<br />

Developmental Biology<br />

62. Gao Z, REST/NRSF: Guardian of the neuronal genome in quiescent stem cells to controls adult<br />

neurogenesis<br />

63. Mogami H, Thrombin - a pathologic factor in preterm labor and preterm rupture of membranes<br />

64. Moon J, Systematic analysis of Wnt/Hh small molecule inhibitors in zebrafish<br />

65. Meadows S, Neuronal guidance cues direct dorsal aortae formation during vasculogenesis<br />

66. Deering T, Genome-wide ChIP-seq analysis of the components of the PTF1 complex in the mouse<br />

pancreas<br />

Imaging and Nanomedicine<br />

67. Zhou K, Selective “ON/OFF” activation of tunable and pH-responsive fluorescence nanoprobes in<br />

different endocytic organelles<br />

68. Huang X, “On-Off” pH-responsive 19F imaging nanoprobes for MRI<br />

69. Zhou Y, Evaluation of pH-sensitive linkers for the development of ß-lapachone prodrug Micelles<br />

70. Huang G, Multifunctional polymeric Micelles for MR imaging and targeted chemotherapy on lung<br />

cancer<br />

Immunology<br />

71. Zhou X, The two Ig gene enhancers, E3 and Ed, are essential for triggering transcription1<br />

72. Patel D, FcRn blockade by Fc engineering ameliorates arthritis in a murine model<br />

73. Qin Z, Antibody against nucleolin in organ transplant recipients<br />

74. Guidry P, An HLA allele frequency-based approach to resolving allelic and genotypic ambiguity in<br />

HLA typing data and its implementation in ImmPort<br />

Microbiology<br />

75. Krachler A, A new class of gram-negative adhesins mediates multivalent, high-affinity binding to<br />

mammalian cells<br />

76. Reddick L, Biophysical characterization of an E. coli secreted effector protein reveals a mechanism of<br />

virulence<br />

77. Parker C, The possible roles of conserved amino acids in the periplasmic domain of<br />

enterohemorrhagic Escherichia coli sensor kinase QseC<br />

Molecular Genetics<br />

78. Aurora A, Protection of the heart against stress-induced calcium overload by microRNA-214<br />

79. Li B, Stable suppression of Glis2/Nephrocystin-7 results in aberrant centrosome duplication and<br />

nuclear division in kidney tubular cells in vitro<br />

80. Zhao T, Ghrelin secretion and its role in survival of famine


Neuroscience<br />

81. Tseng B, Life-long aerobic training preserves white matter integrity: a first look in the masters athlete’s<br />

brain<br />

82. Masiulis Bowen I, How does morphine influence the maturation and dendritic arborization of adultgenerated<br />

dentate gyrus granule cells<br />

83. Xu Y, Self-modulating of Mint1 in its interaction with amyloid precursor protein<br />

84. Petrik D, Small-molecule upregulation of adult neurogenesis in vivo through Mef2-dependent<br />

mechanisms<br />

85. Smith L, Fragile-X mental retardation protein (FMRP) is required for cocaine-induced behavioral<br />

plasticity<br />

86. Taniguchi M, Histone deacetylase 5 limits cocaine reward through cAMP signaling<br />

87. Niu W, Nuclear receptor TLX controls adult neural stem cell activation and positioning<br />

88. Speed H, Impaired synaptic connectivity in the Neuroligin3 R451C mouse model of autism<br />

89. Sephton C, Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes<br />

90. Torres-Altoro M, Neuroprotective strategies for traumatic brain injury<br />

91. Lai H, In vivo cell-type specific targets of Atoh1 (Math1) in dorsal spinal cord interneurons<br />

92. Jakkamsetti V, In vivo induction of ARC mRNA primes CA1 pyramidal cells for MGLUR dependent<br />

ltd<br />

93. Tsai N, Protocadherin-10 mediates MEF2- and FMRP-dependent synapse elimination<br />

94. Amiri A, Mouse model of human autism spectrum disorder: gene targeting in specific brain regions<br />

95. Cui H, Melanocortin-4 receptor signaling in the lateral hypothalamic area regulates acute responses to<br />

high fat diet<br />

96. Chan C, Functional profiling of Rab GTPases in the drosophila nervous system<br />

97. Kumar R, Loss of acetylation at H4k16 in purkinje cells results in Ataxia-Telangiectasia-Like<br />

neurological phenotype<br />

Pharmacology<br />

98. Potthoff M, Molecular and metabolic basis of bile acid sequestrant action on cholesterol and glucose<br />

metabolism<br />

99. Ellison T, Determining the functions and partners of insulin and LXR regulated proteins that control<br />

lipogenesis<br />

100. Owen B, The fasting hormone, FGF21, causes female infertility in mice<br />

101. Holmstrom S, LRH-1 cooperates with PTF1 to regulate exocrine pancreas function<br />

102. Wauson E, The G protein coupled taste receptor T1R1/T1R3 is a novel regulator of mTOR and<br />

autophagy<br />

103. Dioum E, Small molecule regulating pancreatic beta cell function<br />

104. Thomas J, Fully human anti-phosphatidylserine monoclonal antibodies capable of direct and indirect<br />

antiviral activity protects guinea pigs from hemorrhagic arenaviruses<br />

105. Ding X, Beta-Klotho in adipose tissue is required for the anti-obesity effect of Fibroblast Growth<br />

Factor 21 in mice<br />

Physiology<br />

106. Fujimoto N, Effect of aging on left ventricular compliance and distensibility in healthy sedentary<br />

humans<br />

107. Carrick-Ranson G, Left ventricular mass increases with life-long training volume irrespective of<br />

scaling unit<br />

108. Berglund E, Targeted reactivation of leptin receptors in POMC neurons improves glucose


Physiology, continued<br />

homeostasis and hepatic insulin action in the mouse<br />

109. Akgul Y, Changes in glycosaminoglycan (GAG) composition in the cervix during normal pregnancy<br />

and preterm labor<br />

110. Okada Y, Effects of sex on sympathetic neural and hemodynamic responses to head-up tilt in<br />

hypertensive seniors<br />

111. Chang A, Zipper-Interacting Protein Kinase phosphorylates myosin and is associated with<br />

maintenance of cardiac function<br />

112. Piper P, Studying physiologic signals for ghrelin secretion using a novel genetic mouse model of<br />

hyperghrelinemia<br />

113. Mari Y, HDAC inhibitors exert dramatic effects on cholesterol homeostasis in the central nervous<br />

system, but fail to affect the progression of Niemann-Pick type C disease<br />

114. Wernstedt Asterholm I, Fasting-induced changes in the acute-phase response in adipose tissue<br />

115. Kusminski C, MitoNEET: a major regulator of mitochondrial function and lipid homeostasis<br />

116. Jarvis S, Racial differences in neural and humoral control of blood pressure during early pregnancy<br />

117. Zhu Y, Impact of aging and life-long exercise on cerebrovascular CO2 reactivity<br />

Psychiatry<br />

118. Guzman D, Transient inactivation of NMDA receptors in the ventral tegmental area enhances the<br />

incentive motivational properties of cocaine<br />

119. Chuang J, Ghrelin mediates stress-induced food reward behaviors<br />

120. Shukla A, Molecular alterations associated with the COMT val158met polymorphism in<br />

schizophrenia<br />

121. Yanagi M, Immunoquantification of Kv3.2, GAD67 and GAD65 in prefrontal cortex of schizophrenia<br />

and antipsychotics-treated rats<br />

Radiological Sciences<br />

122. Lin C, Detection of paraCEST agents with reduced MT interference using Frequency Labeled<br />

Exchange Transfer (FLEX)<br />

123. Kim S, Bardoxolone methyl, a novel EGFR activator that protects human colonic epithelial cells<br />

against radiation<br />

124. Wang Y, Ultra-pH responsive micellar nanoprobes for cancer molecular imaging<br />

125. Chiguru S, Synthesis and evaluation of F-18 labeled hydroxyquinoline derivatives as PET imaging<br />

agents for early detection of Alzheimer’s plaques<br />

126. Hao G, Dual molecule presentation on a multifunctional scaffold for specific prostate cancer imaging<br />

127. Lumata L, Generating >60,000-fold room-temperature yttrium-89 NMR signal enhancement for<br />

magnetic resonance imaging<br />

Surgery<br />

128. Oni G, A histological comparison of fractional ablative laser treatment in human facial and<br />

abdominal skin - the effect of double pulsing<br />

129. Arain N, A randomized comparison of laparoscopic, magnetically anchored, and flexible endoscopic<br />

cameras on ex-vivo and in-vivo performance and workload for laparoscopic and single incision<br />

surgery


The Symposium Committee acknowledges<br />

the generous support of our corporate sponsors:<br />

Bio-Rad<br />

Clontech<br />

Corning<br />

Crystal Chem<br />

eBioscience<br />

Life Technologies<br />

Miltenyi Biotech<br />

New England Biolabs<br />

Qiagen<br />

Reata<br />

Teklad-Harlan<br />

VWR<br />

Zhang and Associates, P.C.


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Q111006-More-<strong>UT</strong>SW.indd 1<br />

1/14/11 4:28 PM


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A<br />

Akgul, Yucel 109<br />

Alcantara Llaguno, Sheila 27<br />

Amiri, Anahita 94<br />

Annavarapu, Hari Kishore 15<br />

Arain, Nabeel 129<br />

Artyukhin, Alex 59<br />

Aurora, Arin 78<br />

B<br />

Battiprolu, Pavan 40<br />

Berglund, Eric 108<br />

Burchfield, Jana 37<br />

C<br />

Canseco, Diana 42<br />

Carrick-Ranson, Graeme 107<br />

Chan, Chih-Chiang 96<br />

Chang, Audrey 111<br />

Cheng, Hua 58<br />

Cheng, Tzuling 32<br />

Chiguru, Srinivas 125<br />

Chuang, Jen-Chieh 119<br />

Correa, Fernando 11<br />

Cui, Huxing 95<br />

D<br />

Deering, Tye 66<br />

Dellinger, Michael 34<br />

Ding, Xunshan 105<br />

Dioum, Elhadji M 103<br />

Dorwart, Michael 18<br />

E<br />

Ellison, Tara 99<br />

F<br />

Fattah, Kazi 25<br />

Fujimoto, Naoki 106<br />

G<br />

Galindo, Kathleen 33<br />

Gao, Zhengliang 62<br />

Guidry, Paula 74<br />

Guzman , Daniel 118<br />

Alphabetical index of Poster presenters<br />

H<br />

Han, Sungwon 52<br />

Han, Yuhong 7<br />

Hao, Guiyang 126<br />

Hattne, Johan 4<br />

He, Xiaojing 19<br />

Herrera-Herrera, Mireya 51<br />

Holmstrom, Sam 101<br />

Hu, Youcai 56<br />

Huang, Gang 70<br />

Huang, Xiaonan 68<br />

Huang, Yongcheng 9<br />

I<br />

Iglewski, Myriam 36<br />

J<br />

Jakkamsetti, Vikram 92<br />

Jarvis, Sara 116<br />

Jia, Da 13<br />

Jilkine, Alexandra 60<br />

K<br />

Kim, Jaekuk 16<br />

Kim, Sang Bum 123<br />

Krachler, Anne-Marie 75<br />

Kumar, Brajesh 8<br />

Kumar, Rakesh 97<br />

Kusminski, Christine 115<br />

L<br />

Lai, Helen 91<br />

Lai, Hsien-Tsung 48<br />

Larsen, Jill 26<br />

Lee, A-Young 2<br />

Lee, Wan-Ru 44<br />

Li, Bin 10<br />

Li, Binghua 79<br />

Li, Long Shan 22<br />

Lin, Chien-Yuan 122<br />

Lumata, Lloyd 127<br />

M<br />

Mari, Yelenis 113<br />

Marin-Valencia, Isaac 20


Masiulis Bowen, Irene 82<br />

Meadows, Stryder 65<br />

Mogami, Haruta 63<br />

Moon, Jesung 64<br />

Morales, Julio 49<br />

N<br />

Nemchenko, Andriy 38<br />

Ning, Jue 55<br />

Niu, Wenze 87<br />

O<br />

Okada, Yoshiyuki 110<br />

Oni, Georgette 128<br />

Owen, Bryn 100<br />

P<br />

Park, Jangwon 23<br />

Park, Jiyoung 29<br />

Parker, Christopher 77<br />

Patel, Dipesh 72<br />

Petrik, David 84<br />

Piper, Paul 112<br />

Poelwijk, Frank 61<br />

Potthoff, Matthew 98<br />

Potts, Malia 28<br />

Q<br />

Qin, Zhiqiang 73<br />

R<br />

Rabellino, Andrea 30<br />

Ramesh, Arati 17<br />

Reddick, Lovett Evan 76<br />

Reynolds, Kimberly 14<br />

Rotter, David 39<br />

S<br />

Saddar, Sonika 45<br />

Sankella, Shireesha 6<br />

Schaeffer, R. Dustin 1<br />

Schuster, Katja 31<br />

Sephton, Chantelle 89<br />

Shah, Parth 46<br />

Shukla, Abhay 120<br />

Smith, Laura N. 85<br />

Soheili, Arash 57<br />

Song, Kunhua 50<br />

Speed, Haley 88<br />

Stiffler, Michael 5<br />

Sun, Jingxin 35<br />

Sun, Tingwan 12<br />

T<br />

Taniguchi, Makoto 86<br />

Thomas, John 104<br />

Tiwari, Anjana 24<br />

Tomimatsu, Nozomi 54<br />

Torres-Altoro, Melissa I. 90<br />

Tsai, Nien-Pei 93<br />

Tseng, Benjamin 81<br />

W<br />

Wang, Yiguang 124<br />

Wauson, Eric 102<br />

Wernstedt Asterholm, Ingrid 114<br />

Wu, Qian 53<br />

X<br />

Xu, Yibin 83<br />

Y<br />

Yaacoub, Ramy 21<br />

Yanagi, Masaya 121<br />

Yarbrough, Melanie 47<br />

Yu, Seok-Ho 3<br />

Z<br />

Zhang, Qingjun 43<br />

Zhao, Tongjin 80<br />

Zhou, Kejin 67<br />

Zhou, Xiaorong 71<br />

Zhou, Yinjian 69<br />

Zhu, Min 41<br />

Zhu, Yongsheng 117

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