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treatment-emergent ars reported in ≥10%<br />
oF patients Who reCeived sutent or iFnα*<br />
Results of the phase 3, randomized, 1st-line mRCC trial (N=750;<br />
50-mg SUTENT vs 9 MIU IFNα)...<br />
ARs, n (%)<br />
SUTENT (n=375)<br />
IFNα (n=360)<br />
ALL GRADES GRADE 3/4 † ALL GRADES GRADE 3/4 ‡<br />
ARs, n (%)<br />
SUTENT (n=375)<br />
IFNα (n=360)<br />
ALL GRADES GRADE 3/4 † ALL GRADES GRADE 3/4 ‡<br />
CONSTITUTIONAL<br />
Fatigue<br />
Asthenia<br />
Fever<br />
Weight decreased<br />
Chills<br />
Chest pain<br />
Influenza-like illness<br />
GASTROINTESTINAL<br />
Diarrhea<br />
Nausea<br />
Mucositis/stomatitis<br />
Vomiting<br />
Dyspepsia<br />
Abdominal pain §<br />
Constipation<br />
Oral pain<br />
Flatulence<br />
Dry mouth<br />
GERD/reflux esophagitis<br />
Glossodynia<br />
Hemorrhoids<br />
233 (62)<br />
96 (26)<br />
84 (22)<br />
60 (16)<br />
53 (14)<br />
50 (13)<br />
18 (5)<br />
246 (66)<br />
216 (58)<br />
178 (47)<br />
148 (39)<br />
128 (34)<br />
113 (30)<br />
85 (23)<br />
54 (14)<br />
52 (14)<br />
50 (13)<br />
47 (12)<br />
40 (11)<br />
38 (10)<br />
55 (15)<br />
42 (11)<br />
3 (1)<br />
1 (
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