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Continuous Micro Reactor Technology for Drug Substance Synthesis:

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Project Summary and Future Directions<br />

• Data collected and organized<br />

17 days in Toulouse France<br />

• Analysis and Modeling<br />

Evaluation of various modeling<br />

protocols<br />

• PCA, MCR, ALS<br />

Calibrate to GC results (PLS)<br />

• Phase 2 of project<br />

Acquire reactor at CPAC<br />

Focus on reactor control<br />

Implement more sensors<br />

Scale-up vs. scale-out<br />

Real-time product work-up<br />

• Implement Models <strong>for</strong> Process<br />

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