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History of S. aureus Resistance • 1988 2% MRSA • 1991 29% MRSA • Today ~ 70% of S. aureus in USA is MRSA 70 60 % Resistant 50 40 30 20 10 0 1960 1967 1974 1981 1988 1995 2002 USA
Prevalence of MRSA Colonization • Carriage rates in the general population range from 2 to 10% • Recent pediatric study: 36% s. aureus in nares (9% were MRSA) • Higher rates among certain populations – Old (nursing home residents) – Sick (hosp<strong>it</strong>alized, dialysis) – Health care workers (ICU, surgical wards) • One study showed up to 70% colonized
Page 1 and 2: Understanding and Fighting Methicil
Page 3 and 4: Understanding and Fighting Methicil
Page 5 and 6: What is MRSA Methicillin-resistant
Page 7: History of S. aureus Resistance •
Page 11 and 12: Invasive MRSA Infection Incidence
Page 13 and 14: • CDC definitions CA vs. HA MRSA
Page 15 and 16: CA MRSA “Four Pediatric Deaths fr
Page 17 and 18: CA MRSA Outbreaks • Saint Louis R
Page 20 and 21: CA vs. HA MRSA Genetics • Communi
Page 22 and 23: CA MRSA in the hospital USA300 acco
Page 24 and 25: MRSA in the ED • MRSA the most co
Page 26 and 27: How bad can it get • Higher fatal
Page 28 and 29: MRSA Pneumonia • S. aureus is mos
Page 30 and 31: Treatment of MRSA Pneumonia • Van
Page 32 and 33: Treatment of MRSA Pneumonia • No
Page 34 and 35: Management of SSTI Infections • R
Page 36 and 37: • Clindamycin Antibiotic Options
Page 38 and 39: Newer Agents • Linezolid (Zyvox)
Page 40 and 41: • Ceftobiprole Newer Agents - “
Page 42 and 43: Controlling the Spread of MRSA % Re
Page 44 and 45: HA MRSA Risk Factors • Previous a
Page 46: Questions

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