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Material safety data sheet CREMOPHOR RH 40 - Lex doo

Material safety data sheet CREMOPHOR RH 40 - Lex doo

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<strong>Material</strong> <strong>safety</strong> <strong>data</strong> <strong>sheet</strong><br />

Data of edition (edition 2010):06.07.2010<br />

<strong>CREMOPHOR</strong> <strong>RH</strong> <strong>40</strong><br />

1. Identification of the substance/preparation and of the company/undertaking<br />

Product name: <strong>CREMOPHOR</strong> <strong>RH</strong> <strong>40</strong><br />

Company:<br />

<strong>Lex</strong> d.o.o., Vanganelska c. 26, 6000 Koper<br />

Telephone: 05 625-18-10<br />

Telefax: 05 625-18-12<br />

E-mail address:<br />

lex.koper@siol.net<br />

Emergency telephone number: In case of the poisoning consult your doctor or call a poison centre, phone: 112.<br />

2. Hazards identification<br />

Specific hazards:<br />

Not a hazardous substance or preparation.<br />

3. Composition/information on ingredients<br />

Product code: 0237<br />

Use of the substance/preparation:<br />

pharmaceutical substance<br />

Chemical proprieties:<br />

From castor oil, hydrogenated, ethoxylated.<br />

CAS-No.: 61788-85-0<br />

EINECS-No.: 500-147-5<br />

4. First aid measures<br />

General:<br />

After skin contact:<br />

Immediately remove any clothing soiled by the product.<br />

Wash with water and soap and rinse thoroughly.<br />

After eye contact: Wash immediately and thoroughly with running water, keeping eyelids open for at least 15<br />

minutes.<br />

After swallowing:<br />

Rinse mouth and drink with plenty of water.<br />

After inhalation:<br />

Advice to doctor:<br />

Take affected persons out of danger area and lay down. Supply fresh air.<br />

Symptomatic treatment (decontamination, vital functions).<br />

5. Fire-fighting measures<br />

Suitable extinguishing agents:<br />

Special protective equipment for fire-fighters:<br />

Further information:<br />

6. Accidental release measures<br />

Person <strong>safety</strong> precautions:<br />

Environmental precautions:<br />

Methods for cleaning/collecting:<br />

7. Handling and storage<br />

Information for safe handling:<br />

Information about storage in one common storage<br />

facility:<br />

Water, carbon dioxide, foam, dry extinguishing powder.<br />

Use breathing apparatus.<br />

The debris and contaminated extinguishing water must be disposed according to local<br />

regulations.<br />

None in particular.<br />

Do not empty into drains.<br />

Small quantities: collect with appropriate means and wash thoroughly with water.<br />

Large quantities: collect with appropriate means and wash thoroughly with water.<br />

Avoid contact with skin and eyes. It is necessary to observe the usual precautionary measures<br />

for handling the chemicals.<br />

Further information about storage conditions: Store containers tightly closed in a cool and dry<br />

place.<br />

8. Exposure controls/personal protection<br />

Skin protection:<br />

You should select the appropriate protective clothing for the activity and exposure, for<br />

example. Apron, boots and clothing (DIN-EN 465).<br />

Hand protection:<br />

Suitable protective gloves for chemicals (EN 374) even for prolonged direct contact<br />

(Recommendation: protection index 6, corresponding to a breakthrough time > 480 minutes<br />

according to EN 374): e.g. nitrilocaucciù (0.4 mm), chlorinated rubber (0.5 mm), PVC (0.7<br />

mm) and more.<br />

Further information: Data are based on our test <strong>data</strong> and bibliographic information from<br />

glove manufacturers or derive from substances similar in composition. We must also consider<br />

that several factors (e.g. temperature) that impact during the use of a glove protection<br />

against chemical agents, may affect to much lower breakthrough time than the established<br />

one.<br />

Eye protection: Safety glasses with side shields (goggles cage) (e.g. EN 166).<br />

Body protection:<br />

Please observe the usual precautionary measures for handling the chemicals.<br />

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9. Physical and chemical properties<br />

Form:<br />

past<br />

Colour:<br />

white to yellowish<br />

Odour:<br />

almost odourless<br />

pH value: (20 °C, 100 g/l) 6,0 – 7,0<br />

Melting point: 16-26 °C<br />

Flesh point: 242 °C<br />

Auto-ignition temperature: 375 °C<br />

Density: (60 °C) 1,03 kg/cm 3<br />

Solubility in water: (23 °C) > 490 g/l<br />

Solubility in solvents:<br />

Soluble in organic solvents.<br />

Coefficient n-octanol/water (log Pow): -0,76<br />

Viscosity (dynamic): (60 °C) 176 mPa.s<br />

10. Stability and reactivity<br />

Thermal decomposition: 300 °C<br />

Reactions to avoid:<br />

There are no known hazardous reactions if substance is used and stored appropriately.<br />

Hazardous decomposition products:<br />

There are no known hazardous decomposition products.<br />

11. Toxicological information<br />

Irritation:<br />

Sensitization:<br />

Acute toxicity:<br />

Mutagenicity:<br />

Eyes: not irritant (rabbit).<br />

Skin: not irritant (rabbit).<br />

Not sensitizing.<br />

Oral: LD-50: > 20000 mg/kg (rat)<br />

Inhalat.: LC-50: > 2,06 mg/kg (rat), 4 h<br />

Inhalation risk test (IRT): inhalation of a vapour-air mixture has not a highly saturated acute risk<br />

(no mortality within 8 hours).<br />

There was no mutagenic effect in various experiments on bacteria and in on most<br />

mammalian cell cultures that were examined. Even in experiments on animals was no<br />

mutagenic effect. Animal tests have shown no fetal damage.<br />

12. Ecological information<br />

Use product with good working habits and do not allow it, to reach ground water, water course or sewage system.<br />

Persistence and degradability:<br />

BOD (ThOD): 80 -90 % (28 days) - readily biodegradable.<br />

Eco-toxicity: LC50: Oryzias latipes: > 10000 mg / l (48 h)<br />

The test was performed above the maximum solubility. Signs of toxic action are refered to the<br />

nominal concentration.<br />

EC50: Desmodesmus subspicatus: > 100 mg/l (72 h)<br />

Microorganisms / Effect on activated sludge:<br />

EC50: active sludge: > 700 mg (0.5 h / l),<br />

Probably the product is not harmful to aquatic organisms.<br />

The correct placing of low concentrations in biological treatment plant should not affect the<br />

activity of degradation of activated sludge.<br />

13. Disposal considerations<br />

Follow with local officials. Recover if possible. Send to authorized disposal plants or for incineration under controlled conditions. Operate according to<br />

existing local and national regulations.<br />

The unclean packaging must be disposed of as the product.<br />

14. Transport information<br />

Not classified as dangerous in the meaning of transport regulations.<br />

15. Regulatory information<br />

Legislation:<br />

• Official gazette RS, nr. 110/2003, 47/2004)<br />

• Official gazette RS, nr. 35/2005)<br />

• Official gazette RS, nr. 67/2005)<br />

• Official gazette RS, nr. 84/1998, 45/2000, 20/2001, 13/2003, 41/2004)<br />

• Official gazette RS, nr. 104/2000, 12/2002,41/2004)<br />

• Official gazette RS, nr. 9/2003, 66/2003)<br />

• Official gazette RS, nr. 100/2001)<br />

16. Other information<br />

NIOSH -Registry of toxic effects of chemicals substances ( 1983)<br />

I.N.R.S. -Fiche toxicologique<br />

CESIO -Classification and labelling of anionic, nonionic surfactants ( 1990 )<br />

This version replaces all previous versions.<br />

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