Tumor Necrosis Factor

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RESULTS COMBINATION TREATMENTS: TNF , INF-γ , Melphalan (TIM-ILP) Efficacy of TIM-ILP on bulky melanoma metastasis TNF , Melphalan (TM-ILP) Melphalan (M-ILP)
ISOLATED LIMB PERFUSION ADVANTAGES - 80-90% Complete Response - Avoid amputation of the limb - Used in Sarcoma, Melanoma and liver with Hepatic Perfusion - No toxicity of TNF - Selective accumulation of drugs inside the tumor DISADVANTAGES - In metastatic stage the patient dies - Only local administration - Low concentration of TNF promotes angiogenesis - Surgical Approach
Page 1 and 2: Immunologia Ilaria Pelassa Tumor Ne
Page 3 and 4: LIFE OR DEATH Remco v. H. et al.,T
Page 5 and 6: TRAFs Wajant H. et al. TNF receptor
Page 7 and 8: TNF ANTI-NEOPLASTIC EFFECTS ANTITUM
Page 9 and 10: TNF VASCULAR EFFECTS
Page 11 and 12: HYPOTHETICAL MECHANISM OF TNF-α TN
Page 13: ISOLATED LIMB PERFUSION WITH ANTICA
Page 17 and 18: Smyth M.J. et al.,Nature’s TRAIL
Page 19 and 20: WHAT HAPPENS TRAIL TNF TNFR TRAILR
Page 21 and 22: BIBLIOGRAPHY Remco v. H. et al.,TNF

Tumor Necrosis Factor

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