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Multiple Alignment - Bioinformatics and Biological Computing

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ClustalX<br />

ClustalX<br />

<strong>Multiple</strong> alignment in GCG<br />

• The program available in GCG for multiple<br />

alignment is Pileup.<br />

• Pileup does global alignment very similar to<br />

clustalw.<br />

• The input file for Pileup is a list of sequence<br />

file_names or sequence codes in the<br />

database. The list is created by a text<br />

editor.<br />

<strong>Multiple</strong> alignment in GCG<br />

• Pileup creates a multiple sequence<br />

alignment from a group of related<br />

sequences using progressive, pairwise<br />

alignments. It can also plot a tree showing<br />

the clustering relationships used to create<br />

the alignment.

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