URSODIOL FOR PRIMARY BILIARY CIRRHOSIS - AASLD

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<strong>PRIMARY</strong> SCLEROSING CHOLANGITIS Management of specific complications • Dominant biliary strictures – uncommon – cytology insensitive for cancer • other methods (DIA & FISH) being evaluated – long-term stents may cause problems – dilatation alone seems preferable
<strong>PRIMARY</strong> SCLEROSING CHOLANGITIS Specific Therapy • Medical therapy tested to date Penicillamine Colchicine Mycophenolate Mofetil Cyclosporine Methotrexate Silymarin Pentoxifylline Budesonide Tacrolimus Nicotine Pirfenidone Ursodeoxycholic acid Azathioprine Etanercept _____ = possible benefit
Page 1 and 2: Keith D. Lindor, MD Cholestatic Dis
Page 3 and 4: UPDATE • PBC • PSC • Complica
Page 5 and 6: EPIDEMIOLOGY OF PBC Changes Over Ti
Page 7 and 8: PROGNOSTIC MODELS IN PBC Dickson et
Page 9 and 10: OVERLAP FEATURES • IgG > 2.0 mg/d
Page 11: PRIMARY BILIARY CIRRHOSIS • DIAGN
Page 14: DIAGNOSIS OF AMA PBC • Compatible
Page 18 and 19: PREDICTED SURVIVAL RATES Corpechot
Page 20 and 21: SURVIVAL TO DEATH OR LIVER TRANSPLA
Page 22 and 23: COMBINATION THERAPY FOR PBC • Urs
Page 24 and 25: THERAPY FOR PBC - CURRENT RECOMMEND
Page 26 and 27: PRIMARY SCLEROSING CHOLANGITIS •
Page 28: PRIMARY SCLEROSING CHOLANGITIS •
Page 32 and 33: PRIMARY SCLEROSING CHOLANGITIS •
Page 34 and 35: SURVIVAL IN PSC - SMALL DUCT VS. LA
Page 36 and 37: PSC SURVIVAL IN OLMSTED COUNTY MINN
Page 40 and 41: AUTOIMMUNE PANCREATITIS/ CHOLANGITI
Page 42 and 43: HIGH DOSE URSO IN PSC Primary Endpo
Page 44 and 45: Incidence of Cholangiocarcinoma Cum
Page 46 and 47: LIVER TRANSPLANTATION Cholestatic L

URSODIOL FOR PRIMARY BILIARY CIRRHOSIS - AASLD

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