URSODIOL FOR PRIMARY BILIARY CIRRHOSIS - AASLD

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HIGH DOSE URSO IN PSC Primary Endpoints UDCA Placebo Death 3 4 Liver Transplant 9 3 Minimal Listing Criteria for Liver 12 10 Transplant Cirrhosis 5 3 Esophageal and/or Gastric Varices 14 6 Cholangiocarcinoma 2 1
<strong>PRIMARY</strong> SCLEROSING CHOLANGITIS Management of specific complications • Cholangiocarcinoma – may occur in 7-15% – incidence 0.5 to 1% per year – Smoking and IBD risks – Also at risk for liver cell, pancreatic, and colon cancer
Page 1 and 2: Keith D. Lindor, MD Cholestatic Dis
Page 3 and 4: UPDATE • PBC • PSC • Complica
Page 5 and 6: EPIDEMIOLOGY OF PBC Changes Over Ti
Page 7 and 8: PROGNOSTIC MODELS IN PBC Dickson et
Page 9 and 10: OVERLAP FEATURES • IgG > 2.0 mg/d
Page 11: PRIMARY BILIARY CIRRHOSIS • DIAGN
Page 14: DIAGNOSIS OF AMA PBC • Compatible
Page 18 and 19: PREDICTED SURVIVAL RATES Corpechot
Page 20 and 21: SURVIVAL TO DEATH OR LIVER TRANSPLA
Page 22 and 23: COMBINATION THERAPY FOR PBC • Urs
Page 24 and 25: THERAPY FOR PBC - CURRENT RECOMMEND
Page 26 and 27: PRIMARY SCLEROSING CHOLANGITIS •
Page 28: PRIMARY SCLEROSING CHOLANGITIS •
Page 32 and 33: PRIMARY SCLEROSING CHOLANGITIS •
Page 34 and 35: SURVIVAL IN PSC - SMALL DUCT VS. LA
Page 36 and 37: PSC SURVIVAL IN OLMSTED COUNTY MINN
Page 38 and 39: PRIMARY SCLEROSING CHOLANGITIS Mana
Page 40 and 41: AUTOIMMUNE PANCREATITIS/ CHOLANGITI
Page 44 and 45: Incidence of Cholangiocarcinoma Cum
Page 46 and 47: LIVER TRANSPLANTATION Cholestatic L

URSODIOL FOR PRIMARY BILIARY CIRRHOSIS - AASLD

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