Serum ALP & GGT Levels in HIV Positive Patients - Statperson

International Journal of Recent Trends in Science And Technology, ISSN 2277-2812 E-ISSN 2249-8109, Volume 5, Issue 3, 2013 pp 155-157
Serum ALP & GGT Levels in HIV Positive
Patients
Ranjit Patil 1 , Prathamesh Kamble 2* , Uplabdhi Raghuwanshi 3
1 Professor, Department of Medical Biochemistry, Dr. Ulhas Patil Medical College, Jalgaon, Maharashtra, INDIA.
2 Assistant Professor, Department of Physiology, B. J. Government Medical College, Pune, Maharashtra, INDIA.
3
Ph.D. Student, B. J. Government Medical College, Pune, Maharashtra, INDIA.
* Corresponding Address:
dr.prathamesh81@gmail.com
Research Article
Abstract: Analysis of liver-associated enzymes may also help
focus the diagnostic workup. The present study attempts to
assess the following in HIV positive patients – (1) To study
whether the liver functions are deranged in HIV positive
patients by estimating the serum ALP & GGT levels. (2)
Whether or not it can be used as a diagnostic & prognostic tool.
The mean ± SD serum ALP & GGT in control group was
demonstrated to be 43.12 ± 4.13 IU/L & 19.52 ± 2.93 IU/L,
according to the present study, which was found to be increased
to 129.5 ± 126.12 IU/L (p < 0.01) & 57.27 ± 26.35 IU/L
(p

Ranjit Patil, Prathamesh Kamble, Uplabdhi Raghuwanshi
3. Results
Table 1: Mean Age & Sex differentiation in Control & Morbid
Group
Group
Mean Age No. of No. of
(Years) Males Females
Control 35.17 28 12
HIV Positive
Cases
34.65 27 13
The mean age of the control group including morbid
group was calculated to be 35.17 years (22 to 53 years)
& 34.65 years (22 to 55 years) [table 1]. The mean ±
SD serum ALP & GGT level was found to be increased
in HIV positive patients. The increase was statistically
significant (p < 0.01).
Table 2: ALP and GGT levels (Mean ± SD) in Control &
Morbid Group
Mean ± SD
Paramete Range Range
Control Morbid
r [Control] [Morbid]
Group Group
ALP
43.12 ± 129.5 ±
52-35 782-45
[IU/L]
4.13 126.12*
GGT
19.52 ± 57.27 ±
25-15 154-32
[IU/L]
2.93 26.35*
* p < 0.01 (significant when compared to control group)
4. Discussion
According to the present study mean ± SD serum ALP
& GGT in control group was found to be 43.12 ± 4.13
IU/L & 19.52 ± 2.93 IU/L which was increased to 129.5
± 126.12 IU/L (p < 0.01) [Max range = 782 IU/L] &
57.27 ± 26.35 IU/L (p

International Journal of Recent Trends in Science And Technology, ISSN 2277-2812 E-ISSN 2249-8109, Volume 5, Issue 3, 2013 pp 155-157
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Copyright © 2013, Statperson Publications, International Journal of Recent Trends in Science And Technology, ISSN 2277-2812 E-ISSN 2249-8109, Volume 5, Issue 3, 2013