A Case Review Obesity and Effective Ventilation Strategies

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Effective ventilation vs. prevention of injury Ventilation – SpO 2 , PaO 2 , PaCO 2 , ETCO 2 Repetitive opening and closing of unstable lung units – cyclic stretch-------- INJURY Effects of injury- Neutrophil infiltration , rupture of alveolar bronchial attachment, formation of reactive oxygen / nitrogen intermediates, cell death ( necrosis and apoptosis), alteration in alveolar capillary barrier Up regulation of pro inflammatory mediators like TNF-α and interleukin 8 in rabbits given large TV and moderate hyperoxia
Modes and settings Volume Control/Pressure Control Pressure /volume / rate Peak inspiratory pressure / mean peak pressure Plateau pressure I:E ratio Use of PEEP
Page 1 and 2: A Case Review Obesity and Effective
Page 3 and 4: Case Scenario 42 year old female p
Page 5 and 6: How will you ventilate
Page 8 and 9: Respiratory Physiology in Obesity
Page 10 and 11: During Anesthesia (continued) Decr
Page 14 and 15: Peak pressure vs. plateau pressure
Page 16 and 17: Volume control
Page 18 and 19: PEEP In a meta-analysis of eight R
Page 20 and 21: Protective ventilation strategies
Page 22 and 23: Summary Was the pressure control
Page 24 and 25: Treat the cause / Change the settin
Page 26 and 27: References: Pelosi P and Greforett

A Case Review Obesity and Effective Ventilation Strategies

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