Cancer Pain Management: An Overview - Palliative.info

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Fentanyl and Sufentanil • synthetic µ agonist opioids • highly lipid soluble → » transmucosal absorption » rapid redistribution, including in / out of CSF • fentanyl ≈ 100x stronger than morphine • sufentanil ≈ 1000x stronger than morphine 10 mg morphine ≈ 10 µg g sufentanil ≈ 100 µg g fentanyl 50
Comparison of Fentanyl and Sufentanil 3.5 3 2.5 2 Fentanyl Sufentanil 1.5 1 0.5 0 Onset (min) Peak (min) Duration (hr) 51
Page 1 and 2: Cancer Pain Management: An Overview
Page 3 and 4: PHYSICAL PSYCHOSOCIAL SUFFERING EMO
Page 5 and 6: Symptoms At The End of Life in Chil
Page 7 and 8: Somatic Pain • Aching, often cons
Page 9 and 10: Special Considerations in Bone Pain
Page 11 and 12: FEATURES OF NEUROPATHIC PAIN COMPON
Page 13 and 14: Assessment of Bone Pain History: Ph
Page 15 and 16: W.H.O. . ANALGESIC LADDER By the Cl
Page 17 and 18: OPIOIDS and INCOMPLETE CROSS-TOLERA
Page 19 and 20: CONVERTING OPIOIDS NB: Does not con
Page 24 and 25: TOLERANCE PHYSICAL DEPENDENCE PSYCH
Page 26 and 27: PHYSICAL DEPENDENCE Inturrisi C, Ha
Page 28 and 29: In chronic opioid dosing: po / subl
Page 30 and 31: Management of Bone Pain Pharmacolog
Page 32 and 33: Treatment of Neuropathic Pain Pharm
Page 34 and 35: CORTICOSTEROIDS AS ADJUVANTS •
Page 36 and 37: DEXAMETHASONE: DOSING • minimal m
Page 38 and 39: Opioid Side Effects • Constipatio
Page 40: OIN: Recognition • Myoclonus - tw
Page 43 and 44: The Management of Incident Pain in
Page 45 and 46: Circumstances In Which Incident Pai
Page 47 and 48: Having a steady level of enough opi
Page 49: Approach to Incident Pain • treat
Page 53: INCIDENT PAIN PROTOCOL ctd... • f

Cancer Pain Management: An Overview - Palliative.info

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