Staphylococcus aureus

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PFGE‐MRSA USA types USA 400 epidemic from 1998‐2003 PVL, SEB, SEC, Type IV mec element
Prevalence of CA‐MRSA ~2003‐present • Survey of 11 EDs throughout US in Aug 2004 • 422 pts with skin & soft tissue infection • 320/422 (75%) caused by S. <strong>aureus</strong> • MRSA 59% (15% ‐ 74%), USA300 strain 97% • KC 74%; Atlanta 72%, Charlotte NC 68%, New Orleans 67%, Albuquerque 60%, Phoenix 60%, Philadelphia 55%, Portland dO OR 54%, Los Angeles 51%, Minneapolis 39%, New York 15%
Page 1 and 2: Staphylococcus aureus • Significa
Page 3 and 4: Goals • What are the differences
Page 6 and 7: S. aureus lineages (e.g. clonal bac
Page 8: 1999 MMWR • Four Pediatric deaths
Page 11: Superantigen Production CA-MRSA n=3
Page 15 and 16: • USA 300 MRSA most prominent S.
Page 17 and 18: Panton Valentine Leukocidin • Dat
Page 19 and 20: Enhanced or found in USA300 Common
Page 21 and 22: How does the Clinical Microbiology
Page 23: Conclusions • S. aureus USA300 is

Staphylococcus aureus

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