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Medical Emergencies in the Dental Office, Tomas ... - Dmcnet.org

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Gell & Coombs Classification<br />

• Type 1 ( IgE – Mediated Hypersensitivity)<br />

most life threaten<strong>in</strong>g<br />

few m<strong>in</strong>utes<br />

• Type 2 ( Cytotoxic / Cytolytic antibody<br />

mediated) IgM or IgG antibodies mediate<br />

• Type 3 ( Immnune complex mediated )<br />

1- 4 weeks, IgM – IgG soluble metabolite<br />

• Type 4 (delayed Hypersensitivity )<br />

sensitized T cell lymphocytes

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