ARCHITECT® HIV Ag/Ab Combo: Moving HIV ... - The AIDS Institute
ARCHITECT® HIV Ag/Ab Combo: Moving HIV ... - The AIDS Institute
ARCHITECT® HIV Ag/Ab Combo: Moving HIV ... - The AIDS Institute
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ARCHITECT <strong>HIV</strong> <strong>Combo</strong> Seroconversion Sensitivity<br />
• Based on 31 panels, <strong>Combo</strong> reduced window period a median of 7 days<br />
relative to 3 rd generation <strong>Ab</strong> assay; range 0-20 days 1<br />
Seroconversion Panel <strong>HIV</strong> 9079 (Vendor data: ZeptoMetrix Corp)<br />
Roche Cobas ARCHITECT BioRad<br />
Days RNA copies/mL <strong>Combo</strong> BioRad 1/2/O Unigold Multispot Oraquick <strong>HIV</strong>-1 WB<br />
0 not detected 0.12 0.648 - - -<br />
2 not detected 0.07 0.133 - - -<br />
9 not detected 0.15 2.116 - - -<br />
18 not detected 0.10 0.580 - - -<br />
20 not detected 0.10 0.177 - - -<br />
28 not detected 0.11 0.222 - - -<br />
33 not detected 0.08 0.102 - - -<br />
35 >400 0.15 0.352 - - -<br />
40 271,000 3.58 0.287 - - - -<br />
42 >750,000 23.85 0.119 - - - -<br />
47 >750,000 43.06 1.065 - - - -<br />
49 >750,000 68.68 2.679 - - - ind<br />
55 211,000 34.81 9.689 - + - ind<br />
57 46,300 3.78 9.949 - + - ind<br />
62 11,000 4.13 10.239 - + - +<br />
64 11,500 8.38 10.239 - + - +<br />
69 21,700 12.83 10.239 - + - +<br />
71 20,400 13.51 10.239 - + - +<br />
76 18,800 19.63 10.239 + + + +<br />
78 26,500 20.99 10.239 + + + +<br />
83 18,700 24.17 10.239 + + + +<br />
85 29,600 24.23 10.239 + + + +<br />
90 23,800 25.15 10.239 + + + +<br />
92 21,100 27.52 10.239 + + + +<br />
97 15,400 29.39 10.239 + + + +<br />
1<br />
ARCHITECT <strong>HIV</strong> <strong>Ag</strong>/<strong>Ab</strong> <strong>Combo</strong> Package Insert<br />
14
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