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From primordial germ cells to oogonia - eshre

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Lateral foldings of the human embryo<br />

from day 24 pc <strong>to</strong> day 28 pc<br />

http://www.indiana.edu/%7eanat550/genanim/latfold/latfold.swf<br />

<strong>From</strong>: Car<strong>to</strong>on of Indiana University Educational System<br />

The yolk sac containing the<br />

PGCs lines the developing gut<br />

during early development<br />

35 410<br />

2 13<br />

Thus, PGCs are part of the<br />

89 16<br />

developing gut at all times<br />

before and during the lateral<br />

folding.<br />

Therefore, PGCs just have <strong>to</strong><br />

be translocated from the gut<br />

through the dorsal mesentery<br />

<strong>to</strong> the gonadal ridges – not<br />

from the yolk-sac

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