IonWorks Quattro Assay - Molecular Devices
IonWorks Quattro Assay - Molecular Devices
IonWorks Quattro Assay - Molecular Devices
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Screening Nav1.7 State-Dependent Blockers<br />
using <strong>Quattro</strong><br />
Prepulse Vh = -140 mV<br />
Prepulse Vh = -70 mV<br />
Columns<br />
1 (R,R)-reboxetine<br />
2 dibucaine<br />
3 (+/-)-fluoxetine<br />
4 vinpocetine<br />
5 verapamil<br />
6 propafenone<br />
7 lamotrigine<br />
8 riluzole<br />
9 (S)-(-)bupivacaine<br />
10 imipramine<br />
11 tetracaine<br />
12 ambroxol<br />
10ms<br />
-20mV<br />
> 50% Block<br />
10ms<br />
-20mV<br />
3000ms<br />
-140mV<br />
3000ms<br />
-70mV<br />
-140mV<br />
50ms<br />
-140mV<br />
50ms
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