IonWorks Quattro Assay - Molecular Devices
IonWorks Quattro Assay - Molecular Devices
IonWorks Quattro Assay - Molecular Devices
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FLIPR-384: ΔVm Can Identify Blockers<br />
Na +<br />
12 known<br />
blockers<br />
A<br />
B<br />
C<br />
Na +<br />
-- channel<br />
-50mV<br />
opener<br />
Baseline<br />
fluorescence<br />
+ +<br />
+10mV<br />
Increased<br />
fluorescence<br />
Concentration (µM)<br />
0<br />
D<br />
E<br />
0.14<br />
F<br />
G<br />
0.41<br />
H<br />
I<br />
1.23<br />
J<br />
K<br />
3.70<br />
L<br />
M<br />
11.11<br />
N<br />
O<br />
33.33<br />
P<br />
100.00<br />
Range = ( -2000, 60000 )