ELECTRIC FIELD MEASUREMENT USING MRI - UTEE

ELECTRIC FIELD MEASUREMENT USING MRI
P. Fiala 1 , K. Bartusek 2 , J. Mikulka 3
1,3
Department of Theoretical and Experimental Electrical Engineering, University of
Technology Brno, Kolejni 4, 612 00 Brno, tel. +420541149510, fax. +420541149512,
www.feec.vutbr.cz/utee, fialap@feec.vutbr.cz, xmikul16@stud.feec.vutbr.cz
2 Institute of Scientific Instruments, Academy of Sciences of the Czech Republic,
Královopolská 147, 612 64 Brno, Czech Republic bar@isibrno.cz,
http://www.feec.vutbr.cz/UTEE, http://www.isibrno.cz
ABSTRACT: The paper describes a test of an electric field on water molecules
based on the present knowledge of the problem as discussed by references [6]-
[11]. The basic configuration of the test was experimentally verified at the
Institute of Scientific Instruments, Academy of Sciences of the Czech Republic.
We also prepared other tests using a different type of substance to find the relation
between the MRI and the macroscopic electric field intensity. As a matter of fact,
it respects the classical Electrodynamics and Material Wave Theory (MWT). The
experiments are intended for future applications in the field of health service.
1 INTRODUCTION
In recent years the research in this field has been focused on the search of different ways of
treating various types of diseases like tumors, viruses, and other micro- and nanoscopic
problems [1],[2]. The papers referred to in this study analyze the impact of an external electric
field application on the development and persistence of tumor diseases. For example, paper
[3] analyzes - depending on the effect of external influences, namely electromagnetic fields -
the mechanisms of emergence of a cell and its uncontrolled development phase. The research
carried out by the laboratory specialists of Norfolk University, USA [4], [5] features the
analysis of the impact of impulse electromagnetic fields on tissue structure changes, genetic
code changes, and the types of controlled variation in selected parts of an organism. The basic
experiments and studies of the impact of electric and electromagnetic fields on the
development of tumor diseases have been presented by prof. Kikuchi [6]. The previous
published studies [2], however, had not entirely respected the complex electro- magnetohydro-
dynamic (EMHD) principles of approach. According to the data available, the phases
of a tumor disease development are classified into four stages as related to the status of a cell.
The first two of these stages are reversible; within the remaining ones, however, distinctive
changes in the cell metabolism are recorded and, given the standard weak EMHD effects in
the latter two stages, the principles of cell change become irreversible. The research
conducted by Norfolk University is markedly oriented toward analyzing the latter two stages
in the development of a cell within a tumor formation. In comparison with this research
orientation, we have focused our research distinctly on the former two development stages.
The elementary approach to the problem consists in finding a suitable numerical model to
analyze the impact of an electromagnetic field on the basic chemical structure elements.

Within the process of numerical analysis, we perform the testing of the impact of an electric
field on a small volume of purified homogeneous H 2 O water. In this respect, the
interdependence is sought between the impacts of size, direction, and instantaneous course of
the electric field intensity on the molecular properties of the material (water). Further,
experiments are performed using the Nuclear Magnetic Resonance (NMR) and the Magnetic
Resonance Imaging (MRI), and the shift and variation of the spectral line of the examined
sample are monitored. In the process of the verification of laws resulting from the MWT and
the available plus verifiable theories [7]-[13], the procedure of an electric field impact
analysis will be directed toward more complex organic structures. The elementary findings of
the sample status in the NMR testing are further completed with numerical analysis [13].
2 MRI EXPERIMENTS
In order to set the NMR method, both the impacts thereof on the resulting image and the
material in-homogeneity impact on the processing of the NMR image were examined and
numerically modeled [15]. Further, to support the analysis of the impact of an electric field
depending on the instantaneous value and size of electric field E intensity on the samples that
can be located close to the operator, we developed special controlled voltage sources with
output voltage regulation of U out =1-100kV and current limitation (to the value of current
manageable by a human organism) within the range of I out 0-1mA. Figs. 1 and 2 show the
conception of the controlled, high-voltage source. This problem is analyzed in greater detail
by the [14] reference study.
Fig.1 A High Voltage source compact conception - the model, the scheme and the experimental measurement
This work deals with the design of an electronically controlled high-voltage power source
used for special purposes. The source will be used to set up the intensity of an electric field on
predefined shapes of material samples, from simple inorganic to complex organic materials.
The design must fulfill the condition of a constant setting of the source's output current. The
regulation ranges should be: output voltage U o =1-100kV, electric current I max =10µA-10mA,
frequency f=0-1kHz. The device must satisfy safety requirements specified by Czech
standards (ČN). Several designs have been prepared on the basis of available materials, and

one was selected and realized: a circuit with an offline fly-back regulator, regulated with
pulse-width modulation frequency f m =30 kHz. The power source was realized and its
specifications were experimentally verified. The electronic control wiring diagram of the
high-voltage source with current limitation is shown in fig. 3. The numerical analysis results
were experimentally verified using the 200 MHz/75 mm MR tomograph at the ISI, AS CR (fig. 9).
The tomograph elementary magnetic field B 0 = 4,7000 T is generated by a superconducting horizontal
magnet produced by the Magnex Scientific company. The resonance frequency for the cores 1 H is
200 MHz. From the measurements performed using the MRI we obtained the results of the electric
field intensity E impact on the cores of the H 2 O sample; an overview of these results is provided in
tab. 1. Further, experiments were carried out on the H 2 O sample using a device with a system of
electrodes. There was a distance of 20mm between the electrodes, which were fixed to a laboratory
beaker containing the water sample. The fixation was realized in such a manner as to eliminate the
displacement current effects on all the surfaces and dielectric volumes. Leakage current was secured,
with the resulting assurance of operator safety. Then, the first measurement without the electric field
intensity E impact on the examined sample showed the centre on the frequency of f 0 =184Hz. After
connecting voltage to the electrodes and producing the electric field intensity of 50kV/m-4050kV/m,
we managed repeatedly to measure the resonance line shift of ∆f = 4 Hz. Thus, the influence was
experimentally proved of the electric field static intensity on the motion and behavior of water
molecule cores. According to the well-known relation between the change of frequency and the
change of magnetic induction [15], the change of magnetic induction is
Fig.2 High Voltage source component conception and one module of the source
Fig.3 High Voltage source diagram of electronic control

2π
∆f
2π
∆f
∆ B = = (1)
8
γ 2,6710
where f [Hz] is the frequency, γ [T -1 .s -1 ] is the gyro-magnetic ratio of water, and ∆B [T] is
the change of magnetic flux density module distribution in the sample. Then, the change of
magnetic induction corresponds with ∆B= 94.1 nT.
Tab. 1 The measured resonance frequency shifts
Electric Field Intensity Ez [kV/m]
Resonance frequency offset
[Hz]
+4050 +4
+2025 +4
0 0
-2025 +3
-4050 +3
Fig. 4 Elementary configuration
of the MR magnet for the
200MHz tomograph, ISI ASCR
Fig.5 MR experimental workplace and equipment

20 15 10 5 0 -5 -10 -15 -20
∆f=4Hz
Fig. 6. The measured spectral characteristics of the water sample, ∆f = 4 Hz (resonance frequency
without the electric field is f 0 =184 Hz)
3 CONCLUSION
The presented paper contains the results of experiments analyzing the impact of an electric
(static) field on the behaviour of elementary compounds cores. The study represents a step
forward in the analysis of the more complex chemical substances behaviour as related to the
impact of an electric field. The results of EMHD theories were taken into account in studying
the task, and an MWT-based model was used for the numerical support thereof.
6 ACKNOWLEDGMENTS
The research described in the paper were financially supported by FRVŠ by research plan
No. MSM 0021630516, ELCOM-No. MSM 0021630513 , grant GAAV No. B208130603 and
prof. H. Kikuchi for the consultations and advises.
7 REFERENCES
[1] Schoelkopf R.J, Girvin S.M "Wiring up quantum systems", NATURE, The
international weekly journal of science, 7-th of February 2008
[2] The European Journal of Surgery, Supplement 574, Proceedings of the IABC
International association for Biologically closed electric circuits (BCEC) in Medicine
and Biology, Scandinavian University press, Oslo-Cpenhagen-Stockholm, 1994
[3] Daivid E. Effectiveness and risk during application of NLW from the medical point of
view, Non-lethal options enhancing security and stability, 3 rd European Symposium on
Non-lethal Weapons , May 10-12, 2005, Ettlingen, SRN
[4] Tammo Heeren, J. Thomas Camp, Juergen F. Kolb, Karl H. Schoenbach, Sunao
Katsuki, and Hidenori Akiyama, 250 kV Subnanosecond Pulse Generator with
Adjustable Pulsewidth, IEEE Trans. Diel. Electr. Insul. 14, pp. 884-888 (2007).
[5] Y. Sun, S. Xiao, J. A. White, J. F. Kolb, M. Stacey, and K H. Schoenbach, Compact,
Nanosecond, High Repetition-Rate, Pulse Generator for Bioelectric Studies, IEEE
Trans. Diel. Electr. Insul. 14, pp. 863-870 (2007).

[6] Kikuchi, H. Electro-Plasma Macrostructure and Functioning of a Mono-Cancer-
Tumor or Scatered Fine-Grained Tumors Analogous to a Dust Grain or Grains in
Dusty Plasmas PIERS 1999, March, USA, 1999.
[7] van Vlaenderen K.J. and A.Waser,“Electrodynamics with the scalar field,” Physics,
Vol.2, 1-13, 2001.
[8] Kikuchi H Electrohydrodynamics in dusty and dirty plasmas, gravito-electrodynamics
and EHD, Kluwer academic publishers, Dordrecht/Boston/London, 2001.
[9] van Vlaenderen K.J. A charge space as the orogin of sources, fields and potentials,
Physics, arXiv:physics/9910022 v1 16 Oct 1999, 1-13, 1999.
[10] Hofer W.A. “A charge space as the origin of sources, fields and potentials,” Physics,
arXiv: quant-ph/ 9611009 v3 17 Apr 1997, 1997.
[11] Prosser V a kolektiv . Experimentální metody biofyziky, Academia, Praha, 1989.
Delong A. “Verbal information” Czech Academy of Science, ISI Brno, 7.2.2006 Brno,
2006.
[12] Bartusek K.-Fiala P. A simple numerical simulation of internal structure of particles
test PIERS 2007, BEIJING, China, 2007.
[13] FIALA, J. Special electronics controlled HV sources, Diploma Thesis, Brno: FEEC
BUT v Brno, Czech Republic, 2007. pp73.
[14] Bartusek K.-Fiala P. Experiments with the effect of non-homogenous parts into
materials PIERS 2008, Hangzhou, March, China, 2008.