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Appendix table - Harvard Medical School - Health Care Policy

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<strong>Appendix</strong> Table 2. Individual-level consistency of DSM-IV diagnoses of GAD based on dichotomized screening scales with gold<br />

standard diagnoses in key validation studies a<br />

AUC SN LR+ SP LR- (n) Sample b Clinical Outcome<br />

I. CIDI-SC<br />

.81 .68 11.1 .94 0.3 (206) PC SCID (First et al., 2002)<br />

II. GAD-7 (Spitzer et al., 2006)<br />

.85 .89 4.9 .82 0.1 (2,740) PC (Kroenke et al., 2007) SCID (First et al., 2002)<br />

.74 .83 2.4 .65 0.3 (157) INT (Donker et al., 2011) CIDI (Robins et al., 1988)<br />

.79 .83 3.3 .75 0.2 (343) PC (Houston et al., 2011) SCID (First et al., 2002)<br />

III. Other<br />

WB-DAT .78 .63 10.5 .94 0.4 (193) MHS (Farvolden et al., 2003) SCID (First et al., 2002)<br />

SDDS-PC .83 .90 3.9 .77 0.1 (635) PC (Broadhead et al., 1995) SCID (First et al., 2002)<br />

WSQ .78 .93 1.7 .45 0.2 (157) INT (Donker et al., 2009) CIDI (Robins et al., 1988)<br />

a SN = Sensitivity of the screening scale; LR+ = likelihood ratio positive of the screening scale; SP = specificity of the<br />

screening scale; LR- = likelihood ratio negative of the screening scale.<br />

b<br />

PC = Primary care screening sample; MHS = Mental health specialty screening sample; COM = Community survey; INT =<br />

Internet screening sample<br />

2

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