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11<br />
The <strong>Royal</strong> <strong>Marsden</strong><br />
Octreotide vs Hyoscine Butylbromide<br />
– Mystakidou et al (2002)<br />
– 68 patients with inoperable bowel obstruction<br />
– Randomised to receive hyoscine butylbromide or<br />
octreotide<br />
– Significant improvement in octreotide arm with<br />
respect to:<br />
– Nausea<br />
– Vomiting<br />
– Fatigue<br />
– Anorexia<br />
– No difference in relation to pain<br />
– BUT low doses of hyoscine butylbromide used
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