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Safety Manual - Spms

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SCHOOL OF PHYSICAL & MATHEMATICAL SCIENCES<br />

LABORATORY SAFETY MANUAL<br />

We need to:<br />

<br />

<br />

<br />

Prepare ourselves for the labeling, starting from single substance.<br />

Educating/ Training lab users on the new GHS labeling system.<br />

Update our SDS database and GHS label when change(s) made.<br />

For more information, please visit:<br />

http://www.unece.org/trans/danger/publi/ghs/ghs_rev02/02files_e.html<br />

9.4 Hazardous Substances<br />

Many substances which we encounter in the laboratory are known to be toxic,<br />

corrosive or combination of both. We may also frequently encounter new and<br />

untested substances that maybe hazardous to us. Chemicals that are flammable<br />

and/or explosive pose another significant hazard. Therefore, it is essential that<br />

all laboratory users understand the types of toxicity and are familiar with the<br />

major hazard classes of chemicals. It would be important to treat all compounds<br />

as potentially harmful, especially new and unfamiliar materials, and work with<br />

them under conditions to minimize exposure by skin contact and inhalation.<br />

Hazardous Substances with Toxic Effects on Specific Organs<br />

Category Effects on organs Examples<br />

Hepatotoxins Liver damage Nitrosamines, Carbon<br />

Tetrachloride<br />

Nephrotoxins Kidneys damage Certain halogenated<br />

hydrocarbons<br />

Neurotoxins Nervous system Mercury, Acrylamide,<br />

Carbon Disulfide<br />

- Decrease haemoglobin<br />

function & deprive body<br />

tissues of oxygen<br />

Carbon monoxide and<br />

Cyanides<br />

- Damage of Lung tissue Asbestos and Silica<br />

COLLEGE OF SCIENCE 35

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