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Olyset Plus – meeting the world’s changing needs. Contents Introduction and Background....................................................................1 Controlled Release Technology ................................................................5 Biological Efficacy ......................................................................................6 Technical Specifications ..........................................................................10 Usage and Safety ......................................................................................12
Introduction and Background Introduction Mosquito nets have a long history of protecting people from malarial mosquitoes but it was not until the introduction of treating nets with pyrethroid insecticides that bed nets changed from being a physical barrier to being an insecticidally active tool which both deters and kills mosquitoes. The original method of dipping nets in insecticide solution was very labour intensive and logistically difficult in the field and the treatment rarely survived more than three washes. The situation changed dramatically with the introduction of factory-treated, wash-proof, long lasting insecticide treated nets (LLINs) in which the insecticide is either bound to the surface of the net fibre or incorporated inside the fibre itself. Olyset ® Net – Pioneering Technology with Added Durability Sumitomo Chemical was the first company to develop and pioneer fibre incorporation technology. We realised that incorporation of insecticide into the fibre, using controlled release technology that allows insecticide to migrate to the surface and maintain a regular supply, is better than `gluing` to the fibre surface which leaves the insecticide vulnerable to removal by abrasion or washing. In addition, the use of high-density polyethylene (HDPE) rather than polyester as the fibre material gives major advantages in both the strength and durability of the net. Olyset Plus, like the original Olyset Net, has a denier of >150 whereas commonly available polyester nets are 75 – 100 denier. As denier is one of the major contributors to strength and durability in the field, Olyset Plus is therefore approximately 1.5 - 2 times stronger than typical 75 – 100 denier polyester LLINs. Olyset Net was the first LLIN to pass the World Health Organization Pesticide Evaluation Scheme (WHOPES). Since then, many more nets have passed WHOPES with either interim or full recommendation. However, all these nets—including Olyset Net—are manufactured using a single class of insecticides known as pyrethroids, on account of their excellent activity against mosquitoes and low mammalian toxicity. Emerging insecticide resistance – a real threat Due to the excellent results from using LLINs, donors campaigned and advocated for mass distribution of bednets throughout Africa and in many other endemic countries. Universal coverage (at least 80% coverage with LLINs of at-risk populations) was achieved in many African countries by early 2011. The pressure of only using pyrethroids in LLINs, and their extensive use in indoor residual spraying programs as well as in agriculture, has resulted in insecticide resistance in mosquito vector populations in some parts of the world, particularly in Africa. ‘At the time of this report, resistance to at least one insecticide has been identified in 64 countries with on-going malaria transmission. Resistance to pyrethroids Key Features • Fine mesh. • Softer feel. • Excellent biological performance against mosquitoes. • Enhanced knockdown and kill against pyrethroid-resistant mosquitoes. • Contains the synergist – piperonyl butoxide (PBO) on all surfaces. • Insecticide and synergist incorporated inside fibres. • Insecticide and synergist migrate to fibre surface continuously over many years. • Re-generation of both active ingredients. • Unique to market. • A second generation of the well proven Olyset Net. • Japanese technology. seems to be the most widespread.*’ The extent and threat of resistance to the use of LLINs and on actual malaria cases is not well understood and there are large programmes planned to monitor and check the impact on transmission. * WHO Global Plan for Insecticide Resistance Management in malaria vectors (GPIRM), 2012 1
Page 1: Registered trademark of Sumitomo Ch
Page 5 and 6: y extensive use and misuse of the s
Page 7 and 8: Controlled Release Technology Incor
Page 9 and 10: or killing effect. Blood Feeding In
Page 11 and 12: Olyset Plus gave very good BFI that
Page 13 and 14: Structural formula: Piperonyl Butox
Page 15 and 16: Olyset Plus nets are ready to use.

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